Hans K Hasselbalch

Hans K Hasselbalch

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2024
  2. Published

    JAK2V617F drives gut microbiota differences in patients with myeloproliferative neoplasms

    Eickhardt-Dalbøge, C. S., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Andersen, L. O., Lilje, B., Larsen, Morten Kranker, Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Sørensen, A. L., Ellervik, Christina, Olsen, L. R., Christensen, J. J. E., Nielsen, X. C., Hasselbalch, Hans Carl & Ingham, A. C., 2024, In: European Journal of Haematology. 112, 5, p. 776-787 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    CHIP-JAK2V617F, chronic inflammation, abnormal megakaryocyte morphology, organ failure, and multimorbidties

    Hasselbalch, Hans Carl, Kristiansen, M. H., Kjær, L., Skov, V., Larsen, Morten Kranker, Ellervik, Christina & Wienecke, Troels, 2024, In: Blood advances. 8, 3, p. 681-682 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  4. Published

    Neutrophil-to-lymphocyte ratio and all-cause mortality with and without myeloproliferative neoplasms-a Danish longitudinal study

    Larsen, Morten Kranker, Skov, V., Kjær, L., Eickhardt-Dalbøge, C. S., Knudsen, T. A., Kristiansen, M. H., Sørensen, A. L., Wienecke, Troels, Andersen, M., Ottesen, J. T., Gudmand-Høyer, J., Snyder, J. A., Andersen, M. P., Torp-Pedersen, Christian, Poulsen, Henrik Enghusen, Stiehl, T., Hasselbalch, Hans Carl & Ellervik, Christina, 2024, In: Blood Cancer Journal. 14, 1, 12 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms

    Gotfredsen, K., Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 11 Mar 2023, In: Scientific Reports. 13, 1, p. 4077 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon-alpha2

    Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Ellervik, Christina, Larsen, Morten Kranker, Kjær, L., Skov, V., Hasselbalch, Hans Carl & Ottesen, J. T., 2023, In: Cancer Medicine. 12, 4, p. 4218-4226

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    An arginase1- and PD-L1-derived peptide-based vaccine for myeloproliferative neoplasms: A first-in-man clinical trial

    Grauslund, J. H., Holmström, M. O., Martinenaite, E., Lisle, T. L., Glöckner, H. J., Fassi, Daniel El , Klausen, U., Mortensen, R. E. J., Jørgensen, N., Kjær, L., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1117466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Case Report: First longitudinal study of a patient with CALR positive clonal hematopoiesis of indeterminate potential developing into pre-fibrotic myelofibrosis

    Kjær, L., Skov, V., Larsen, Morten Kranker, Boklund, T. I., Andersen, M., Kefala, Maria, Knudsen, T. A., Schjellerup Eickhardt-Dalbøge, C., Stiehl, T., Gudmand-Høyer, J., Snyder, J., Holmström, M., Andersen, M. H., Ottesen, J. T., Ellervik, Christina & Hasselbalch, Hans Carl, 2023, In: Frontiers in Oncology. 13, 8 p., 1176173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Elevated white blood cell counts in ischemic stroke patients are associated with increased mortality and new vascular events

    Vo, T. P., Kristiansen, M. H., Hasselbalch, Hans Carl & Wienecke, Troels, 2023, In: Frontiers in Neurology. 14, 8 p., 1232557.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Event-free survival in patients with polycythemia vera treated with ropeginterferon alfa-2b versus best available treatment

    the PROUD-PV Study Group, T. P. S. G., 2023, In: Leukemia. 37, 10, p. 2129-2132 4 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Published

    High JAK2V617F variant allele frequency is associated with coronary artery but not aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms

    Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, Christina, Hasselbalch, Hans Carl & Bruun, Niels Eske, 2023, In: European Journal of Haematology. 111, 3, p. 400-406 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Interferon alpha-2 treatment reduces circulating neutrophil extracellular trap levels in myeloproliferative neoplasms

    Massarenti, Laura, Knudsen, T. A., Enevold, Christian, Skov, V., Kjær, L., Larsen, M. K., Larsen, T. S., Hansen, D. L., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, 2023, In: British Journal of Haematology. 202, 2, p. 318-327 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study

    Kristiansen, M. H., Kjær, L., Skov, V., Larsen, Morten Kranker, Ellervik, Christina, Hasselbalch, Hans Carl & Wienecke, Troels, 2023, In: Blood advances. 7, 19, p. 5825-5834 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Pronounced gut microbiota signatures in patients with JAK2V617F-positive essential thrombocythemia

    Eickhardt-Dalbøge, C. S., Ingham, A. C., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Andersen, L. O., Larsen, Morten Kranker, Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Ellervik, Christina, Olsen, L. R., Hasselbalch, Hans Carl, Elmer Christensen, J. J. & Nielsen, X. C., 2023, In: Microbiology Spectrum. 11, 5, 19 p., e0066223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms

    Hasselbalch, Hans Carl, Junker, P., Skov, V., Kjær, L., Knudsen, T. A., Larsen, Morten Kranker, Holmström, M. O., Andersen, Mads Hald, Jensen, C., Karsdal, M. A. & Willumsen, N., 2023, In: Cancers. 15, 17, 47 p., 4323.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    The gut microbiota in patients with polycythemia vera is distinct from that of healthy controls and varies by treatment

    Eickhardt-dalbøge, C. S., Ingham, A. C., Andersen, L. O., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Larsen, M. K., Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Ellervik, C., Olsen, L. R., Hasselbalch, Hans Carl, Nielsen, X. C. & Christensen, J. J. E., 2023, In: Blood advances. 7, 13, p. 3326-3337 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Therapeutic cancer vaccination against mutant calreticulin in myeloproliferative neoplasms induces expansion of specific T cells in the periphery but specific T cells fail to enrich in the bone marrow

    Holmström, M. O., Andersen, M., Traynor, S., Ahmad, S. M., Lisle, T. L., Handlos Grauslund, J., Skov, V., Kjær, L., Ottesen, J. T., Gjerstorff, M. F., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1240678.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2022
  20. Published

    Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, Jun 2022, In: PLoS ONE. 17, 6, 16 p., e0269960.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b

    PROUD-PV Study Grp, P. S. G., May 2022, In: Leukemia. 36, 5, p. 1408-1411 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  22. Published

    Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

    Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, Ho, V. T., Hobbs, G. S., Knudsen, T. A., Skov, V., Kjær, L., Larsen, T. S., Hansen, D. L., Lindsley, R. C., Hasselbalch, Hans Carl, Grauslund, J. H., Lisle, T. L., Met, Özcan, Wilkinson, P., Greenbaum, B., Sepulveda, M. A., Chan, T., Rampal, R., Andersen, Mads Hald, Abdel-Wahab, O., Bhardwaj, N., Wolchok, J. D., Mullally, A. & Merghoub, T., 2022, In: Science Translational Medicine. 14, 649, eaba4380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Clonal haematopoiesis of indeterminate potential and impaired kidney function—A Danish general population study with 11 years follow-up

    Larsen, Morten Kranker, Skov, V., Kjær, L., Møller-Palacino, N. A., Pedersen, R. K., Andersen, M., Ottesen, J. T., Cordua, S., Poulsen, Henrik Enghusen, Dahl, Morten, Knudsen, T. A., Eickhardt-Dalbøge, C. S., Koschmieder, S., Pedersen, K. M., Çolak, Y., Bojesen, Stig Egil, Nordestgaard, Børge, Stiehl, T., Hasselbalch, Hans Carl & Ellervik, Christina, 2022, In: European Journal of Haematology. 109, 5, p. 576-585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Coronary artery- and aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms

    Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, Christina, Fuchs, A., Sigvardsen, P. E., Kühl, J. T., Kofoed, Klaus Fuglsang, Nordestgaard, Børge, Hasselbalch, Hans Carl & Bruun, Niels Eske, 2022, In: International Journal of Cardiology. 364, p. 112-118 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genomic profiling of a randomized trial of interferon-a vs hydroxyurea in MPN reveals mutation-specific responses

    Knudsen, T. A., Skov, V., Stevenson, K., Werner, L., Duke, W., Laurore, C., Gibson, C. J., Nag, A., Thorner, A. R., Wollison, B., Hansen, D. L., Ellervik, C., Fassi, D. E., de Stricker, K., Ocias, L. F., Brabrand, M., Bjerrum, O. W., Overgaard, U. M., Frederiksen, M., Kristensen, T. K. & 12 others, Kruse, T. A., Thomassen, M., Mourits-Andersen, T., Severinsen, M. T., Stentoft, J., Starklint, J., Neuberg, D. S., Kjaer, L., Larsen, T. S., Hasselbalch, Hans Carl, Lindsley, R. C. & Mullally, A., 2022, In: Blood advances. 6, 7, p. 2107-2119 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Healthcare resource utilization in patients with myeloproliferative neoplasms: A Danish nationwide matched cohort study

    Christensen, S. F., Svingel, L. S., Kjaersgaard, A., Stenling, A., Darvalics, B., Paulsson, B., Andersen, Christen Bertel L, Christiansen, C. F., Stentoft, J., Starklint, J., Severinsen, M. T., Clausen, M. B., Hilsoe, M. H., Hasselbalch, Hans Carl, Frederiksen, H., Mikkelsen, E. M. & Bak, M., 2022, In: European Journal of Haematology. 109, 5, p. 526-541 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms favorably impacts deregulation of oxidative stress genes and antioxidative defense mechanisms

    Skov, V., Thomassen, M., Kjær, L., Ellervik, Christina, Larsen, Morten Kranker, Knudsen, T. A., Kruse, T. A. & Hasselbalch, Hans Carl, 2022, In: PLoS ONE. 17, 6 , e0270669.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression

    Carnaz Simões, A. M., Holmström, M. O., Aehnlich, P., Rahbech, A., Radziwon-Balicka, A., Zamora, C., Wirenfeldt Klausen, T., Skov, V., Kjær, L., Ellervik, Christina, Fassi, Daniel El , Vidal, S., Hasselbalch, Hans Carl, Andersen, Mads Hald & thor Straten, P., 2022, In: Frontiers in Immunology. 13, 866610.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 2849472