Gitta Wörtwein

Gitta Wörtwein

Associate Professor

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    ORCID: 0000-0001-6981-7885

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    1. Published

      Time course and duration of changes in Kv7.2 and Kv11.1 mRNA expression in the hippocampus and piriform cortex following electroconvulsive stimulations

      Hjaeresen, M., Hageman, I., Wörtwein, Gitta & Jørgensen, Martin Balslev, 2012, In: Brain Stimulation. 5, 1, p. 55-60 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      The role of glucagon-like peptide 1 (GLP-1) in addictive disorders

      Kruse Klausen, M., Thomsen, Morgane, Wörtwein, Gitta & Fink-Jensen, Anders, 2022, In: British Journal of Pharmacology. 179, 4, p. 625-641 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      The impact of maternal separation on adult mouse behaviour and on the total neuron number in the mouse hippocampus

      Fabricius, K., Wörtwein, Gitta & Pakkenberg, B., 2008, In: Brain Structure and Function (Print Edition). 212, 5, p. 403-416 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice

      Sorensen, G., Reddy, I. A., Weikop, Pia, Graham, D. L., Stanwood, G. D., Wörtwein, Gitta, Galli, A. & Fink-Jensen, Anders, 1 Oct 2015, In: Physiology & Behavior. 149, p. 262-268 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      The effect of subchronic fluoxetine treatment on learning and memory in adolescent rats

      Sass, A. & Wörtwein, Gitta, 2012, In: Behavioural Brain Research. 228, 1, p. 169-75 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The effect of erythropoietin on electroconvulsive stimulation induced cognitive impairment in rats

      Kjær, K., Jørgensen, Martin Balslev, Hageman, Ida, Miskowiak, Kamilla & Wörtwein, Gitta, 2020, In: Behavioural Brain Research. 382, 112484.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      The circadian oscillator of the cerebral cortex: molecular, biochemical and behavioral effects of deleting the Arntl clock gene in cortical neurons

      Bering, Tenna, Carstensen, M. B., Wörtwein, Gitta, Weikop, Pia & Rath, Martin Fredensborg, Feb 2018, In: Cerebral Cortex. 28, 2, p. 644–657

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Subjective perception of cocaine reward in mice assessed by a single exposure place preference (sePP) paradigm

      Runegaard, A. H., Jensen, Kathrine Louise, Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2017, In: Journal of Neuroscience Methods. 289, p. 85-92 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Socially isolated rats exhibit changes in dopamine homeostasis pertinent to schizophrenia

      Fabricius, K., Steiniger-Brach, B., Helboe, L., Fink-Jensen, Anders & Wörtwein, Gitta, 2011, In: International Journal of Developmental Neuroscience. 29, 3, p. 347-50 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      SUBCHRONIC LOW DOSE EXENDIN-4 PRETREATMENT INHIBITS RELAPSE TO ALCOHOL DRINKING IN HIGH ALCOHOL PREFERING C57BL6 MICE

      Dencker, D., Egecioglu, E., Jerlhag, E., Wörtwein, Gitta, Weikop, Pia, Fink-Jensen, Anders & Molander, A., 2015, In: Alcohol and Alcoholism. 50, suppl 1, p. i17-i18 2 p., SY15-2.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    11. Published

      Role for M5 muscarinic acetylcholine receptors in cocaine addiction

      Fink-Jensen, A., Fedorova, I., Wörtwein, Gitta, Woldbye, David Paul Drucker, Rasmussen, T., Thomsen, M., Bolwig, T. G., Knitowski, K. M., McKinzie, D. L., Yamada, M., Wess, J. & Basile, A., 2003, In: Journal of Neuroscience Research. 74, 1, p. 91-6

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Retention and relearning of spatial delayed alternation in rats after combined or sequential lesions of the prefrontal and parietal cortex

      Wörtwein, Gitta, Mogensen, J. & Divac, I., 1993, In: Acta Neurobiologiae Experimentalis. 53, p. 357-366

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Retention and relearning of spatial delayed alternation in rats after ablation of the prefrontal or total non-prefrontal isocortex

      Wörtwein, Gitta, Mogensen, J. & Divac, I., 1994, In: Behavioural Brain Research. 63, p. 127-131

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Responses of young and aged rat CNS to partial cholinergic immunolesions and NGF treatment

      Wörtwein, Gitta, Yu, J., Toliver-Kinsky, T. & Perez-Polo, J., 1998, In: Journal of Neuroscience Research. Vol. 52, p. 322-333

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice

      Thomsen, M. M., Woldbye, David Paul Drucker, Wörtwein, Gitta, Fink-Jensen, A., Wess, J. & Caine, S. B., 2005, In: Journal of Neuroscience. Vol. 25, p. 8141-49

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Proinflammatory biomarkers are associated with prediabetes in patients with schizophrenia

      Mller, M., Fredholm, S., Jensen, M. E., Wörtwein, Gitta, Larsen, J. R., Vilsbøll, Tina, Ødum, Niels & Fink-Jensen, Anders, 2022, In: CNS Spectrums. 27, 3, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Place learning in scolopamine-treated rats: the role of distal cues and catecholaminergic mediation

      Mogensen, J., Christensen, L. H., Johansson, A., Wörtwein, Gitta, Bang, L. E. & Holm, S., 2002, In: Neurobiology of Learning and Memory. 78(1), p. 139-66

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Place learning during inhibition of nitric oxide synthase in the rat

      Mogensen, J., Hasman, A. & Wörtwein, Gitta, 1995, In: Homeostasis. 36, p. 12-18

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Place learning by fimbria-fornix transected rats in a modified water maze

      Wörtwein, Gitta, Særup, L. H., Charlottenfeld-Starpov, D. & Mogensen, J., 1995, In: International Journal of Neuroscience. 82, p. 71-81

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Place learning and object recognition by rats subjected to transection of the fimbria-fornix and/or ablation of the prefrontal cortex

      Mogensen, J., Lauritsen, K. T., Elvertorp, S., Hasman, A., Moustgaard, A. & Wörtwein, Gitta, 2004, In: Brain Research Bulletin. Vol. 63, no. 3, p. 217-36

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Pharmacological characterization of social isolation-induced hyperactivity

      Fabricius, K., Helboe, L., Fink-Jensen, Anders, Wörtwein, Gitta & Steiniger-Brach, B., 2011, In: Psychopharmacology. 215, 2, p. 257-66 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

      Jensen, Kathrine Louise, Sørensen, G., Dencker, D., Owens, W. A., Rahbek-Clemmensen, T., Brett Lever, M., Runegaard, A. H., Riis Christensen, N., Weikop, Pia, Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth Lindegaard, Daws, L., Gether, Ulrik & Rickhag, Karl Mattias, 2018, In: eNeuro. 5, 3

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Nortriptyline mediates behavioral effects without affecting hippocampal cytogenesis in a genetic rat depression model

      Petersén, A., Wörtwein, Gitta, Gruber, S. H. M., El-Khoury, A. & Mathé, A. A., 2009, In: Neuroscience Letters. 451, 2, p. 148-51 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice

      Elbrønd-Bek, H., Olling, J. D., Gøtzsche, C. R., Waterfield, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, 9 Jul 2014, In: Synapse. 68, 10, p. 427-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine

      Sørensen, G., Wegener, G., Hasselstrøm, J., Hansen, T. V. O., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2009, In: NeuroReport. 20, 11, p. 1023-6 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference

      Sørensen, G., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, Apr 2013, In: Pharmacology, Biochemistry and Behavior. 105, p. 151-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.

      Sørensen, G., Jensen, M., Weikop, Pia, Nielsen, D. D., Christiansen, S. H. O., Loland, Claus Juul, Bengtsen, C. H., Petersen, Jørgen Holm, Fink-Jensen, Anders, Wörtwein, Gitta & Woldbye, David Paul Drucker, Feb 2012, In: Psychopharmacology. 222, p. 565-577 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Muscarinic Acetylcholine Receptor Subtypes as Potential Drug Targets for the Treatment of Schizophrenia, Drug Abuse and Parkinson's Disease

      Dencker, D., Thomsen, M., Wörtwein, Gitta, Weikop, Pia, Cui, Y., Jeon, J., Wess, J. & Fink-Jensen, Anders, 22 Nov 2011, In: ACS Chemical Neuroscience. 3, 2, p. 80-89 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Model for aging inthe basal forebrain cholinergic system

      Wörtwein, Gitta, Gu, Z., Yu, J. & Perez-Polo, J. R., 2000, In: Antioxidants & Redox Signaling. 2,3, p. 437-447

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Membrane permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

      Rickhag, Karl Mattias, Owens, W., Winkler, M., Strandfelt, K. N., Rathje, Mette, Sørensen, G., Andresen, B., Madsen, Kenneth Lindegaard, Nygaard Jørgensen, T., Wörtwein, Gitta, Woldbye, David Paul Drucker, Sitte, H. H., Daws, L. C. & Gether, Ulrik, 2013, In: Journal of Biological Chemistry. 288, p. 27534-44 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Mekanismer ved funktionel restitution efter hjerneskader

      Wörtwein, Gitta, 2009, Klinisk neuropsykologi. Gade, A., Gerlach, C., Starrfelt, R. & Møller Pedersen, P. (eds.). København: Frydenlund Academic, p. 480-488

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    32. Published

      Maternal separation affects male rat copulatory behaviour and hypothalamic corticotropin releasing factor in concert

      Greisen, M. H., Bolwig, T. G., Husum, H., Nedergaard, P. & Wörtwein, Gitta, 2005, In: Behavioural Brain Research. 158(2), p. 367-375

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Markers of HPA-axis activity and nucleic acid damage from oxidation after electroconvulsive stimulations in rats

      Jørgensen, Anders, Breitenstein, K., Kalliokoski, Otto, Weimann, A., Henriksen, T., Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev & Wörtwein, Gitta, 2019, In: Acta Neuropsychiatrica. 31, 6, p. 287-293 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

      Runegaard, A. H., Sørensen, Andreas Toft, Fitzpatrick, C. M., Jørgensen, Søren Heide, Petersen, A. V., Hansen, Nikolaj Winther, Weikop, Pia, Andreasen T., Jesper, Mikkelsen, Jens D., Perrier, Jean-Francois Marie, Woldbye, David Paul Drucker, Rickhag, Karl Mattias, Wörtwein, Gitta & Gether, Ulrik, 2018, In: eNeuro. 5, 3, 26 p., e0345.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      L-Nitroarginine reduces hippocampal mediation of place learning in the rat

      Mogensen, J., Wörtwein, Gitta, Gustafson, B. & Ermens, P., 1995, In: Neurobiology of Learning and Memory. 64, p. 17-24

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Ketogenic Diet suppresses Alcohol Withdrawal Syndrome in Rats

      Dencker, D., Molander, A., Thomsen, M., Schlumberger, C., Wörtwein, Gitta, Weikop, P., Benveniste, H., Volkow, N. D. & Fink-Jensen, Anders, Feb 2018, In: Alcoholism: Clinical and Experimental Research. 42, 2, p. 270-277

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline

      Dencker, D., Wörtwein, Gitta, Weikop, Pia, Jeon, J., Thomsen, M., Sager, T. N., Mørk, A., Woldbye, David Paul Drucker, Wess, J. & Fink-Jensen, Anders, 2011, In: Journal of Neuroscience. 31, 16, p. 5905-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Involvement of Y5 receptors in neuropeptide Y agonist-induced analgesic-like effect in the rat hot plate test

      Thomsen, M., Wörtwein, Gitta, Olesen, M. V., Begtrup, M., Havez, S., Bolwig, T. G. & Woldbye, David Paul Drucker, 2007, In: Brain Research. 1155, p. 49-55

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Initial rewarding effects of cocaine and amphetamine assessed in a day using the single-exposure place preference protocol

      Runegaard, A. H., Jensen, Kathrine Louise, Wörtwein, Gitta & Gether, Ulrik, 2019, In: European Journal of Neuroscience. 50, 3, p. 2156-2163 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Increased numbers of orexin/hypocretin neurons in a genetic rat depression model

      Mikrouli, E., Wörtwein, Gitta, Soylu, R., Mathé, A. A. & Petersén, Å., 2011, In: Neuropeptides (Sheffield). 45, 6, p. 401-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Increased dopaminergic activity in socially isolated rats: an electrophysiological study

      Fabricius, K., Helboe, L., Fink-Jensen, Anders, Wörtwein, Gitta, Steiniger-Brach, B., Sotty, F., Fabricius, K., Helboe, L., Fink-Jensen, Anders, Wörtwein, G., Steiniger-Brach, B. & Sotty, F., 27 Sep 2010, In: Neuroscience Letters. 482, 2, p. 117-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.

      Schmidt, L. S., Thomsen, M., Weikop, Pia, Nielsen, D. D., Wess, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Fink-Jensen, Anders, 2011, In: Psychopharmacology. 216, 3, p. 367-378 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice

      Schmidt, L. S., Miller, A. D., Lester, D. B., Bay-Richter, C., Schülein, C., Frikke-Schmidt, H., Wess, J., Blaha, C. D., Woldbye, David Paul Drucker, Fink-Jensen, Anders & Wörtwein, Gitta, 2010, In: Psychopharmacology. 207, 4, p. 547-58 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats

      Greisen, M. H., Altar, C. A., Bolwig, T. G., Whitehead, R. E. & Wörtwein, Gitta, 2005, In: Journal of Neuroscience Research. 79/6, p. 772-778

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Inactivation of the cholinergic M4 receptor results in a disinhibited endophenotype predicting alcohol use

      Molander, A., Thorbek, D. D., Lysne, C., Weikop, Pia, Fink-Jensen, Anders & Wörtwein, Gitta, 2022, In: Behavioural Brain Research. 430, 10 p., 113921.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      INACTIVATION OF THE CHOLINERGIC M4 RECEPTOR RESULTS IN THE DEVELOPMENT OF A LOW ANXIETY ENDOPHENOTYPE PREDICTING FUTURE ALCOHOL CONSUMPTION

      Dencker, D., Wörtwein, Gitta, Lysne, C., Weikop, Pia, Fink-Jensen, Anders & Molander, A., 2015, In: Alcohol and Alcoholism. 50, suppl 1, p. i57-i58 2 p., P-49.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    47. Published

      Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels

      Reddy, I. A., Pino, J. A., Weikop, Pia, Osses, N., Sørensen, G., Bering, T., Valle, C., Bluett, R. J., Erreger, K., Wörtwein, Gitta, Reyes, J. G., Graham, D., Stanwood, G. D., Hackett, T. A., Patel, S., Fink-Jensen, Anders, Torres, G. E. & Galli, A., 2016, In: Translational Psychiatry. 6, 11 p., e809.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Gene-environment interaction affects substance P and neurokinin A in the entorhinal cortex and periaqueductal grey in a genetic animal model of depression: implications for the pathophysiology of depression

      Husum, H., Wörtwein, Gitta, Andersson, W., Bolwig, T. G. & Mathé, A. A., 2008, In: International Journal of Neuropsychopharmacology. 11, 1, p. 93-101 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      G protein-coupled receptor signaling in VTA dopaminergic neurons bidirectionally regulates the acute locomotor response to amphetamine but does not affect behavioral sensitization

      Runegaard, A. H., Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2019, In: Neuropharmacology. 161, 107663.

      Research output: Contribution to journal › Review › Research › peer-review

    50. Published

      Functional and neurochemical profile of place learning after L-nitro-arginine in the rat

      Mogensen, J., Wörtwein, Gitta, Hasman, A., Nielsen, P. & Wang, Q., 1995, In: Neurobiology of Learning and Memory. 63, p. 54-65

      Research output: Contribution to journal › Journal article › Research › peer-review

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