Gitta Wörtwein
Associate Professor
Section of Environmental Health
Ãster Farimagsgade 5, 1014 København K, 05 Ãster Farimagsgade 5, Building: 05-1-08
Member of:
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5-HT2A Receptor Binding in the Frontal Cortex of Parkinson's Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study
Rasmussen, N. B., Olesen, M. V., Brudek, T., Plenge, P., Klein, A. B., Westin, J. E., Fog, K., Wörtwein, Gitta & Aznar, S., 2016, In: Parkinson’s Disease. 2016, 8 p., 3682936.Research output: Contribution to journal › Journal article › Research › peer-review
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A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter
Rickhag, Karl Mattias, Herborg, Freja, Sørensen, G., Strandfelt, K. N., Andresen, B., Gotfryd, K., Madsen, Kenneth Lindegaard, Vestergaard-Klewe, I., Ammendrup-Johnsen, I., Eriksen, J., Newman, A. H., Füchtbauer, E., Gomeza, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Gether, Ulrik, 2013, In: Nature Communications. 4, p. 1-13 13 p., 1580.Research output: Contribution to journal › Journal article › Research › peer-review
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A chronic increase of corticosterone age-dependently reduces systemic DNA damage from oxidation in rats
Jørgensen, Anders, Kalliokoski, Otto, Forsberg, K., Breitenstein, K., Weimann, A., Henriksen, T., Hau, Jann, Wörtwein, Gitta, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, Mar 2017, In: Free Radical Biology & Medicine. 104, p. 64-74 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors
Jeon, J., Dencker, D., Wörtwein, Gitta, Woldbye, David Paul Drucker, Cui, Y., Davis, A. A., Levey, A. I., Schütz, G., Sager, T. N., Mørk, A., Li, C., Deng, C., Fink-Jensen, Anders, Wess, J., Jeon, J., Nielsen, D. D., Wörtwein, G., Woldbye, D. P. D., Cui, Y., Davis, A. A., Levey, A. I., Schütz, G., Sager, T. N., Mørk, A., Li, C., Deng, C., Fink-Jensen, Anders & Wess, J., 10 Feb 2010, In: Journal of Neuroscience. 30, 6, p. 2396-405 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels
Christensen, R., Marcussen, A. B., Wörtwein, Gitta, Knudsen, G. M. & Aznar, S., 2008, In: Experimental Neurology. 210, 1, p. 164-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Addiction-Related Effects of DOV 216,303 and Cocaine: A Comparative Study in the Mouse
Sørensen, G., Husum, H., Brennum, L. T., Bundgaard, C., Montezinho, L. C. P., Mørk, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, Jun 2014, In: Basic & Clinical Pharmacology & Toxicology. 114, 6, p. 451-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adult Brain and Behavioral Effect of Early Life Maternal Deprivation
Mathe, A. A., El Khoury, A., Gruber, S. H. M., Husum, H., Wörtwein, Gitta & Arlinde, C., 2009, Beyond neuropsychiatric diagnostics: Symptoms not disorders. Palomo, T., Beninger, R. J., Kostzewa, R. M. & Archer, T. (eds.). Mountain Home, TN, USA: F. P. Graham Publishing Co.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine
Nielsen, D. D., Weikop, Pia, Sørensen, G., Woldbye, David Paul Drucker, Wörtwein, Gitta, Wess, J. & Fink-Jensen, Anders, 2012, In: Psychopharmacology. 224, 2, p. 277-87 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of response patterns during prefrontally ablated rats acquisition of an egocentric spatial task in an 8-arm radialmaze
Mogensen, J., Montero, A. & Wörtwein, Gitta, 2003, In: Homeostasis. Vol. 42, no.1-2, p. 52-59Research output: Contribution to journal › Journal article › Research › peer-review
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Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.
Fink-Jensen, Anders, Schmidt, L. S., Dencker, D., Schülein, C., Wess, J., Wörtwein, Gitta & Woldbye, David Paul Drucker, 10 Apr 2011, In: European Journal of Pharmacology. 656, 1-3, p. 39-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aripiprazole blocks acute self-administration of cocaine and is not self-administered in mice
Sørensen, G., Sager, T. N., Petersen, Jørgen Holm, Brennum, L. T., Thøgersen, P., Hee Bengtsen, C., Thomsen, M., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2008, In: Psychopharmacology. 199, 1, p. 37-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat
Madsen, T. M., Kristjansen, P. E. G., Bolwig, T. G. & Wörtwein, Gitta, 2003, In: Neuroscience. Vol. 119, p. 635-42Research output: Contribution to journal › Journal article › Research › peer-review
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Associative an nonassociative learning after chronic imipramine in rats
Mogensen, J., Svendsen, G., Tølbøll Lauritsen, K., Ermens, P., Hasman, A., Elvertorp, S., Plenge, P. K., Mellerup, Erling Thyge & Wörtwein, Gitta, 2003, In: Pharmacology, Biochemistry and Behavior. Vol. 76, p. 197-212Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of epibatidine binding to medial habenula: potential role in analgesia
Plenge, P. K., Mellerup, Erling Thyge & Wörtwein, Gitta, 2002, In: Journal of Pharmacology and Experimental Therapeutics. vol. 302, p. 759-65Research output: Contribution to journal › Journal article › Research › peer-review
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Cholecystokinin tetrapeptide effects on HPA axis function and elevated plus maze behaviour in maternally separated and handled rats
Greisen, M. H., Bolwig, T. G. & Wörtwein, Gitta, 2005, In: Behavioural Brain Research. Vol 161, p. 204-12Research output: Contribution to journal › Journal article › Research › peer-review
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Cholinergic control of nerve growth factor in adult rats: evidence from cortical cholinergic deafferentation and chronic drug treatment
Rossner, S., Wörtwein, Gitta, Gu, Z., Yu, J., Schliebs, R., Bigl, V. & Perez-Polo, J., 1998, In: Journal of Neurochemistry. Vol. 69, p. 947-953Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic electroconvulsive stimulation but not chronic restraint stress modulates mRNA expression of voltage-dependent potassium channels Kv7.2 and Kv11.1 in the rat piriform cortex.
Hjæresen, M., Hageman, Ida, Wörtwein, Gitta, Plenge, P., Jørgensen, Martin Balslev & Wörtwein, Gitta, 2008, In: Brain Research. 1217C, p. 179-184 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic restraint stress in rats causes sustained increase in urinary corticosterone excretion without affecting cerebral or systemic oxidatively generated DNA/RNA damage
Jorgensen, A., Maigaard, K., Wörtwein, Gitta, Hageman, I., Henriksen, T., Weimann, A., Møller, Peter, Loft, Steffen, Hau, Jann, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 10 Jan 2013, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 40, p. 30-37Research output: Contribution to journal › Journal article › Research › peer-review
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Cortical area in the rat that mediates visual pattern discrimination
Wörtwein, Gitta, Mogensen, J., Williams, G., Carlos, J. H. & Divac, I., 1994, In: Acta Neurobiologiae Experimentalis. 54, p. 365-376Research output: Contribution to journal › Journal article › Research › peer-review
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Delayed restraint procedure enhances cognitive recovery of spatial function after fimbria-fornix transection
Gram, M. G., Wogensen, E., Wörtwein, Gitta, Mogensen, J. & Rytter, Hana Malá, 2015, In: Restorative Neurology and Neuroscience. 34, 1, p. 1-17Research output: Contribution to journal › Journal article › Research › peer-review
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Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation
Sørensen, G., Lindberg, C., Wörtwein, Gitta, Bolwig, T. G., Woldbye, David Paul Drucker & Sørensen, G., 1 Sep 2004, In: Journal of Neuroscience Research. 77, 5, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation
Sørensen, G., Rickhag, Karl Mattias, Leo, D., Lycas, M. D., Ridderstrøm, P. H., Weikop, P., Lilja, J. H., Rifes, P., Herborg, Freja, Woldbye, David Paul Drucker, Wörtwein, Gitta, Gainetdinov, R. R., Fink-Jensen, Anders & Gether, Ulrik, 2021, In: Journal of Biological Chemistry. 297, 6, 101361.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic regulation of cerebral DNA repair genes by psychological stress
Forsberg, K., Aalling, Nadia, Wörtwein, Gitta, Loft, Steffen, Møller, Peter, Hau, Jann, Hageman, I., Jørgensen, M. B. & Jørgensen, Anders, 15 Jan 2015, In: Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 778, p. 37-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dyremodeller i neuropsykiatrisk forskning
Mogensen, J. & Wörtwein, Gitta, 1999, Neuropsykiatriske Aspekter. Danmark, p. 116-123Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
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Effects of acute and chronic aripiprazole treatment on choice between cocaine self-administration and food under a concurrent schedule of reinforcement in rats
Thomsen, M., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wörtwein, Gitta, Sager, T., Holm, R., Pepe, L. & Barak Caine, S., 2008, In: Psychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12474
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Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
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PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis
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Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels
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