Flemming Steen Jørgensen
Professor
Structural Biology
Universitetsparken 2
2100 København Ø
- 2017
- Published
Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions
Bonomo, S., Jørgensen, Flemming Steen & Olsen, L., 22 May 2017, In: Journal of Chemical Information and Modeling. 57, 5, p. 1123-1133 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors
Larsen, M., Hansen, C. H., Rasmussen, T. B., Styrishave, Bjarne, Olsen, L. & Jørgensen, Flemming Steen, 28 Feb 2017, In: Chemical Communications. 53, 3118, 4 p., 3118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism
Montefiori, M., Jørgensen, Flemming Steen & Olsen, L., Aug 2017, In: ACS Omega. 2, 8, p. 4237-4244Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region
Tapken, D., Steffensen, T. B., Leth, R., Kristensen, L. B., Gerbola, A., Gajhede, Michael, Jørgensen, Flemming Steen, Olsen, L. & Kastrup, Jette Sandholm Jensen, 7 Apr 2017, In: Scientific Reports. 7, 12 p., 46145.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors
Bonomo, S., Hansen, C. H., Petrunak, E. M., Scott, E. E., Styrishave, Bjarne, Jørgensen, Flemming Steen & Olsen, L., 12 Jul 2016, In: Scientific Reports. 6, 11 p., 29468.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations
Capoferri, L., Leth, R., Ter Haar, E., Mohanty, A. K., Grootenhuis, P. D. J., Vottero, E., Commandeur, J. M. N., Vermeulen, N. P. E., Jørgensen, Flemming Steen, Olsen, L. & Geerke, D. P., Mar 2016, In: Proteins: Structure, Function, and Bioinformatics. 84, 3, p. 383-96 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytochrome P450 Mediated Drug Metabolism
Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Enantioselective endocrine disrupting effects of omeprazole studied in the H295R cell assay and by molecular modeling
Sørensen, A. M., Hansen, C. H., Bonomo, S., Olsen, L., Jørgensen, Flemming Steen, Weisser, J. J., Kretschmann, A. C. & Styrishave, Bjarne, 19 Mar 2016, In: Toxicology in Vitro. 34, p. 71-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters
Aduri, N. G., Prabhala, B. K., Ernst, H. A., Jørgensen, Flemming Steen, Olsen, L. & Mirza, Osman Asghar, 2015, In: The Journal of Biological Chemistry. 290, 50, p. 29931-29940 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction
Leth, R., Rydberg, P., Jørgensen, Flemming Steen & Olsen, L., 23 Mar 2015, In: Journal of Chemical Information and Modeling. 55, 3, p. 660-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302104
Most downloads
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2005
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Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1967
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Forbedret optagelse af lægemidler i organismen: computeren viser vejen
Research output: Contribution to journal › Journal article › Research
Published -
1525
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Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published