Flemming Pociot

Flemming Pociot

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2024
  2. E-pub ahead of print

    Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data

    Teixeira, P. F., Battelino, T., Carlsson, A., Gudbjörnsdottir, S., Hannelius, U., von Herrath, M., Knip, M., Korsgren, O., Elding Larsson, H., Lindqvist, A., Ludvigsson, J., Lundgren, M., Nowak, C., Pettersson, P., Pociot, Flemming, Sundberg, F., Åkesson, K., Lernmark, Å. & Forsander, G., 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2023
  4. Published

    A Gluten-Free Diet during Pregnancy and Early Life Increases Short Chain Fatty Acid-Producing Bacteria and Regulatory T Cells in Prediabetic NOD Mice

    Johansen, Valdemar Brimnes Ingemann, Færø, D., Buschard, K., Kristiansen, Karsten, Pociot, Flemming, Kiilerich, P., Josefsen, K., Haupt-jorgensen, M. & Antvorskov, J. C., 2023, In: Cells. 12, 12, 15 p., 1567.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

    Frørup, C., Gerwig, R., Svane, C. A. S., Mendes Lopes de Melo, J., Henriksen, K., Fløyel, T., Pociot, Flemming, Kaur, S. & Størling, J., 2023, In: Frontiers in Endocrinology. 14, 15 p., 1128523.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis

    Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Svane, C. A. S., Mirza, A. H., Litman, Thomas, Holmskov, U., Bang-Berthelsen, C. H., Vilien, M., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2023, In: Frontiers in Molecular Biosciences. 9, 1081176.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Gene expression signature predicts rate of type 1 diabetes progression

    Suomi, T., Starskaia, I., Kalim, U. U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S., Overbergh, L., Dunger, D., Peakman, M., Chmura, P., Brunak, S., Schulte, A. M., Mathieu, C., Knip, M., Lahesmaa, R., Elo, L. L. & 4 others, Pociot, Flemming, Johannesen, Jesper, Rossing, Peter & INNODIA consortium, I. C., 2023, In: EBioMedicine. 92, 18 p., 104625.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the development of type 1 diabetes

    Rudman, N., Kaur, S., Simunović, V., Kifer, D., Šoić, D., Keser, T., Štambuk, T., Klarić, L., Pociot, Flemming, Morahan, G. & Gornik, O., 2023, In: Diabetologia. 66, 6, p. 1071-1083 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    β Cell and Autophagy: What Do We Know?

    Mohammadi-Motlagh, H. R., Sadeghalvad, M., Yavari, Niloofar, Primavera, R., Soltani, S., Chetty, S., Ganguly, A., Regmi, S., Fløyel, T., Kaur, S., Mirza, A. H., Thakor, A. S., Pociot, Flemming & Yarani, R., 2023, In: Biomolecules. 13, 4, 649.

    Research output: Contribution to journalReviewpeer-review

  10. 2022
  11. Published

    Anti-diabetic potential of Urtica Dioica: current knowledge and future direction

    Chehri, A., Yarani, R., Yousefi, Z., Novin Bahador, T., Shakouri, S. K., Ostadrahimi, A., Mobasseri, M., Pociot, Flemming & Araj-Khodaei, M., 2022, In: Journal of Diabetes and Metabolic Disorders. 21, 1, p. 931-940 10 p.

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Children at onset of type 1 diabetes show altered N-glycosylation of plasma proteins and IgG

    Rudman, N., Kifer, D., Kaur, S., Simunović, V., Cvetko, A., Pociot, Flemming, Morahan, G. & Gornik, O., 2022, In: Diabetologia. 65, 8, p. 1315-1327 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Diabetes complications and extracellular vesicle therapy

    Soltani, S., Mansouri, K., Parvaneh, S., Thakor, A. S., Pociot, Flemming & Yarani, R., 2022, In: Reviews in Endocrine and Metabolic Disorders. 23, p. 357–385

    Research output: Contribution to journalReviewpeer-review

  14. Published

    Differences in insulin sensitivity in the partial remission phase of childhood type 1 diabetes: a longitudinal cohort study

    Mørk, F. C. B., Madsen, J. O. B., Jensen, Andreas Kryger, van Hall, Gerrit, Pilgaard, Kasper Ascanius, Pociot, Flemming & Johannesen, Jesper, 2022, In: Diabetic Medicine. 39, 2, 9 p., 14702.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Differentially Expressed miRNAs in Ulcerative Colitis and Crohn's Disease

    Yarani, R., Shojaeian, A., Palasca, Oana, Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2022, In: Frontiers in Immunology. 13, 21 p., 865777.

    Research output: Contribution to journalReviewpeer-review

  16. Published

    Does rapid sequence divergence preclude RNA structure conservation in vertebrates?

    Seemann, Ernst Stefan, Mirza, A. H., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Workman, C. T., Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan & Ruzzo, W. L., 2022, In: Nucleic Acids Research. 50, 5, p. 2452-2463 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes

    Wegeberg, A. M., Okdahl, T., Riahi, S., Ejskjaer, N., Pociot, Flemming, Størling, J., Brock, Birgitte & Brock, C., 2022, In: Cardiovascular Diabetology. 21, 1, 10 p., 5.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    Extracellular Vesicle Therapy for Type 1 Diabetes

    Soltani, S., Mansouri, K., Emami Aleagha, M. S., Moasefi, N., Yavari, Niloofar, Shakouri, S. K., Notararigo, S., Shojaeian, A., Pociot, Flemming & Yarani, R., 2022, In: Frontiers in Immunology. 13, 865782.

    Research output: Contribution to journalReviewpeer-review

  19. Published

    Genetic Variants Associated with Neuropeptide Y Autoantibody Levels in Newly Diagnosed Individuals with Type 1 Diabetes

    Mansachs, S. J., Villumsen, S. O., Johannesen, Jesper, Lind, A., Kaur, S. & Pociot, Flemming, 2022, In: Genes. 13, 5, 869.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci

    Hajdarevic, R., Lande, A., Mehlsen, J., Rydland, A., Sosa, D. D., Strand, E. B., Mella, O., Pociot, Flemming, Fluge, Ø., Lie, B. A. & Viken, M. K., 2022, In: Brain, Behavior, and Immunity. 102, p. 362-369 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    High-Throughput Human Complement C3 N-Glycoprofiling Identifies Markers of Early Onset Type 1 Diabetes Mellitus in Children

    Šoić, D., Keser, T., Štambuk, J., Kifer, D., Pociot, Flemming, Lauc, G., Morahan, G., Novokmet, M. & Gornik, O., 2022, In: Molecular and Cellular Proteomics. 21, 10, 100407.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Low-grade inflammation in type 2 diabetes: A cross-sectional study from a Danish diabetes outpatient clinic

    Okdahl, T., Wegeberg, A. M., Pociot, Flemming, Brock, Birgitte, Størling, J. & Brock, C., 2022, In: BMJ Open. 12, 12, 10 p., e062188.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    PDE12 in type 1 diabetes

    Tekin, H., Josefsen, K., Krogvold, L., Dahl-Jørgensen, K., Gerling, I., Pociot, Flemming & Buschard, K., 2022, In: Scientific Reports. 12, 18149.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes

    Al-Sari, N., Kutuzova, Svetlana, Suvitaival, T., Henriksen, P., Pociot, Flemming, Rossing, Peter, McCloskey, D. & Legido-Quigley, C., 2022, In: EBioMedicine. 80, 104032.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells

    Kaur, S., Frørup, C., Mirza, A. H., Fløyel, T., Yarani, R., Colli, M. L., Johannesen, Jesper, Størling, J., Eizirik, D. L. & Pociot, Flemming, 2022, In: Non-coding RNA. 8, 5, 19 p., 69.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    Reference serum percentile values of adiponectin, leptin, and adiponectin/leptin ratio in healthy Danish children and adolescents

    Hamann, T. V., Mørk, F. C. B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Heidemann, M. S., Schou, A. J., Mølgaard, Christian, Pociot, Flemming, Wedderkopp, N. & Johannesen, Jesper, 2022, In: Scandinavian Journal of Clinical and Laboratory Investigation. 82, 4, p. 267-276 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    The effect of saffron supplementation on glycemic parameters: An overview of systematic reviews

    Sadigi, B., Yarani, R., Mirghafourvand, M., Travica, N., Yousefi, Z., Shakouri, S. K., Ostadrahimi, A., Mobasseri, M., Pociot, Flemming, Sanaie, S. & Araj-Khodaei, M., 2022, In: Phytotherapy Research. 36, 9, p. 3444-3458 15 p.

    Research output: Contribution to journalReviewpeer-review

  28. Published

    The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls

    Mork, F. B., Madsen, J. O. B., Pilgaard, Kasper Ascanius, Jensen, Andreas Kryger, Klakk, H., Tarp, J., Bugge, A., Heidemann, M., van Hall, Gerrit, Pociot, Flemming, Wedderkopp, N. & Johannesen, Jesper, 2022, In: Pediatric Diabetes. 23, 7, p. 1064-1072 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  29. 2021
  30. Published

    Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity

    Pedersen, K., Haupt-Jorgensen, M., Krogvold, L., Kaur, S., Gerling, I. C., Pociot, Flemming, Dahl-Jørgensen, K. & Buschard, K., Aug 2021, In: Diabetologia. 64, 8, p. 1805-1815 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Skap2, a candidate gene for type 1 diabetes, regulates b-cell apoptosis and glycemic control in newly diagnosed patients

    Fløyel, T., Meyerovich, K., Prause, Michala Cecilie Burstein, Kaur, S., Frørup, C., Mortensen, H. B., Nielsen, L. B., Pociot, Flemming, Cardozo, A. K. & Størling, J., 2021, In: Diabetes. 70, 2, p. 464-476 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

    Kaur, S., Mirza, A. H., Overgaard, A. J., Pociot, Flemming & Størling, J., 2021, In: Frontiers in Genetics. 12, 630109.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Cathepsin c regulates cytokine-induced apoptosis in β-cell model systems

    Fløyel, T., Frørup, C., Størling, J. & Pociot, Flemming, 2021, In: Genes. 12, 11, 1694.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post-hoc analysis of a randomized crossover trial

    Al-Sari, N., Schmidt, S., Suvitaival, T., Kim, M., Trošt, K., Ranjan, A. G., Christensen, M. B., Overgaard, A. J., Pociot, Flemming, Nørgaard, Kirsten & Legido-Quigley, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 2, e00213.

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

    Robertson, C. C. & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., 2021, In: Nature Genetics. 53, 7, p. 962-971 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Human pathways in animal models: possibilities and limitations

    Doncheva, Nadezhda Tsankova, Palasca, Oana, Yarani, R., Litman, Thomas, Anthon, Christian, Groenen, M. A. M., Stadler, P. F., Pociot, Flemming, Jensen, Lars Juhl & Gorodkin, Jan, 2021, In: Nucleic Acids Research. 49, 4, p. 1859-1871 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period

    Frørup, C., Mirza, A. H., Yarani, R., Nielsen, L. B., Mathiesen, Elisabeth, Damm, Peter, Svare, J., Engelbrekt, C., Størling, J., Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Kaur, S., 2021, In: Frontiers in Immunology. 12, 744509.

    Research output: Contribution to journalJournal articlepeer-review

  38. 2020
  39. Published

    Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives

    Rasouli, H., Yarani, R., Pociot, Flemming & Popović-Djordjević, J., May 2020, In: Pharmacological Research. 155, 15 p., 104723.

    Research output: Contribution to journalReviewpeer-review

  40. Published

    Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Svensson, Jannet, Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 2, p. 366-376 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Characterization of plasma lipidomics in adolescent subjects with increased risk for type 1 diabetes in the DiPiS cohort

    Andersson Svärd, A., Kaur, S., Trôst, K., Suvitaival, T., Lernmark, Å., Maziarz, M., Pociot, Flemming, Overgaard, A. J. & DiPiS Study Group, D. S. G., 2020, In: Metabolomics : Official journal of the Metabolomic Society. 16, 10, 14 p., 10.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

    Wegeberg, A. L., Okdahl, T., Fløyel, T., Brock, C., Ejskjaer, N., Riahi, S., Pociot, Flemming, Størling, J. & Brock, Birgitte, 2020, In: Mediators of Inflammation. 2020, 10 p., 3590389.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Decreased markers of bone turnover in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 3, p. 505-514

    Research output: Contribution to journalJournal articlepeer-review

  44. Published

    Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes

    Okdahl, T., Brock, C., Floyel, T., Wegeberg, A. L., Jakobsen, P. E., Ejskjaer, N., Pociot, Flemming, Brock, Birgitte & Storling, J., 2020, In: Clinical Endocrinology. 93, 4, p. 419-428

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    Lipidomics of human adipose tissue reveals diversity between body areas

    Al-Sari, N., Suvitaival, T., Mattila, I., Ali, A., Ahonen, L., Trost, K., Henriksen, T. F., Pociot, Flemming, Dragsted, Lars Ove & Legido-Quigley, C., 2020, In: P L o S One. 15, 6, 15 p., e0228521.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Long Noncoding RNAs in Diabetes and β-Cell Regulation

    Kaur, S., Frørup, C., Jensen, V. H., Mirza, A. H., de Melo, J. M. L., Yarani, R., Overgaard, A. J., Størling, J. & Pociot, Flemming, 2020, The Chemical Biology of Long Noncoding RNAs: RNA Technologies. Jurga, S. & Barciszewski, J. (eds.). Springer, Vol. 11. p. 523-544

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  47. Published

    Systemic TNF alpha correlates with residual beta-cell function in children and adolescents newly diagnosed with type 1 diabetes

    Overgaard, A. J., Madsen, J. O. B., Pociot, Flemming, Johannesen, Jesper & Storling, J., 2020, In: BMC Pediatrics. 20, 1, 6 p., 446.

    Research output: Contribution to journalJournal articlepeer-review

  48. Published

    The Rac2 GTPase contributes to cathepsin H-mediated protection against cytokine-induced apoptosis in insulin-secreting cells

    Floyel, T., Mirza, A. H., Kaur, S., Frorup, C., Yarani, R., Storling, J. & Pociot, Flemming, 2020, In: Molecular and Cellular Endocrinology. 518, 11 p., 110993.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Unaffected bone mineral density in Danish children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Journal of Bone and Mineral Metabolism. p. 328–337 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. 2019
  51. Published

    miRNA-27a-3p and miRNA-222-3p as Novel Modulators of Phosphodiesterase 3a (PDE3A) in Cerebral Microvascular Endothelial Cells

    Yasmeen, S., Kaur, S., Mirza, A. H., Larsen, Birger Brodin, Pociot, Flemming & Kruuse, Christina Rostrup, Aug 2019, In: Molecular Neurobiology. 56, 8, p. 5304–5314

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Tu1766 – Dysregulated Lncrnas in Inflammatory Bowel Disease Demonstrate Immune System Related Association Through Guilt-By Association Analysis

    Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 1 May 2019, In: Gastroenterology. 156, 6, p. S-1116 1 p.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins

    Thorsen, S. U., Pipper, C. B., Ellervik, Christina, Pociot, Flemming, Kyvsgaard, J. N. & Svensson, Jannet, 2019, In: Nutrients. 11, 3, 12 p., 543.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Bone turnover markers in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Jørgensen, N. R., Pociot, Flemming & Johannesen, Jesper, 2019, In: Pediatric Diabetes. 20, 5, p. 510-522

    Research output: Contribution to journalReviewpeer-review

  55. Published

    Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs

    Mirza, A. H., Kaur, S., Nielsen, L. B., Størling, J., Yarani, R., Roursgaard, Martin, Mathiesen, Elisabeth, Damm, Peter, Svare, J., Mortensen, H. B. & Pociot, Flemming, 2019, In: Frontiers in Immunology. 10, p. 2543

    Research output: Contribution to journalJournal articlepeer-review

  56. Published

    Capturing residual beta cell function in type 1 diabetes

    Pociot, Flemming, 2019, In: Diabetologia. 62, 1, p. 28-32 5 p.

    Research output: Contribution to journalJournal articlepeer-review

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