Flemming Pociot

Flemming Pociot

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2024
  2. E-pub ahead of print

    Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data

    Teixeira, P. F., Battelino, T., Carlsson, A., Gudbjörnsdottir, S., Hannelius, U., von Herrath, M., Knip, M., Korsgren, O., Elding Larsson, H., Lindqvist, A., Ludvigsson, J., Lundgren, M., Nowak, C., Pettersson, P., Pociot, Flemming, Sundberg, F., Åkesson, K., Lernmark, Å. & Forsander, G., 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    A Gluten-Free Diet during Pregnancy and Early Life Increases Short Chain Fatty Acid-Producing Bacteria and Regulatory T Cells in Prediabetic NOD Mice

    Johansen, Valdemar Brimnes Ingemann, Færø, D., Buschard, K., Kristiansen, Karsten, Pociot, Flemming, Kiilerich, P., Josefsen, K., Haupt-jorgensen, M. & Antvorskov, J. C., 2023, In: Cells. 12, 12, 15 p., 1567.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

    Frørup, C., Gerwig, R., Svane, C. A. S., Mendes Lopes de Melo, J., Henriksen, K., Fløyel, T., Pociot, Flemming, Kaur, S. & Størling, Joachim, 2023, In: Frontiers in Endocrinology. 14, 15 p., 1128523.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis

    Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Svane, C. A. S., Mirza, A. H., Litman, Thomas, Holmskov, U., Bang-Berthelsen, C. H., Vilien, M., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2023, In: Frontiers in Molecular Biosciences. 9, 1081176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Gene expression signature predicts rate of type 1 diabetes progression

    Suomi, T., Starskaia, I., Kalim, U. U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S., Overbergh, L., Dunger, D., Peakman, M., Chmura, P., Brunak, S., Schulte, A. M., Mathieu, C., Knip, M., Lahesmaa, R., Elo, L. L. & 4 others, Pociot, Flemming, Johannesen, Jesper, Rossing, Peter & INNODIA consortium, I. C., 2023, In: EBioMedicine. 92, 18 p., 104625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the development of type 1 diabetes

    Rudman, N., Kaur, S., Simunović, V., Kifer, D., Šoić, D., Keser, T., Štambuk, T., Klarić, L., Pociot, Flemming, Morahan, G. & Gornik, O., 2023, In: Diabetologia. 66, 6, p. 1071-1083 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    β Cell and Autophagy: What Do We Know?

    Mohammadi-Motlagh, H. R., Sadeghalvad, M., Yavari, Niloofar, Primavera, R., Soltani, S., Chetty, S., Ganguly, A., Regmi, S., Fløyel, T., Kaur, S., Mirza, A. H., Thakor, A. S., Pociot, Flemming & Yarani, R., 2023, In: Biomolecules. 13, 4, 649.

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2022
  11. Published

    Anti-diabetic potential of Urtica Dioica: current knowledge and future direction

    Chehri, A., Yarani, R., Yousefi, Z., Novin Bahador, T., Shakouri, S. K., Ostadrahimi, A., Mobasseri, M., Pociot, Flemming & Araj-Khodaei, M., 2022, In: Journal of Diabetes and Metabolic Disorders. 21, 1, p. 931-940 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Children at onset of type 1 diabetes show altered N-glycosylation of plasma proteins and IgG

    Rudman, N., Kifer, D., Kaur, S., Simunović, V., Cvetko, A., Pociot, Flemming, Morahan, G. & Gornik, O., 2022, In: Diabetologia. 65, 8, p. 1315-1327 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Diabetes complications and extracellular vesicle therapy

    Soltani, S., Mansouri, K., Parvaneh, S., Thakor, A. S., Pociot, Flemming & Yarani, R., 2022, In: Reviews in Endocrine and Metabolic Disorders. 23, p. 357–385

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Differences in insulin sensitivity in the partial remission phase of childhood type 1 diabetes: a longitudinal cohort study

    Mørk, F. C. B., Madsen, J. O. B., Jensen, Andreas Kryger, van Hall, Gerrit, Pilgaard, Kasper Ascanius, Pociot, Flemming & Johannesen, Jesper, 2022, In: Diabetic Medicine. 39, 2, 9 p., 14702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Differentially Expressed miRNAs in Ulcerative Colitis and Crohn's Disease

    Yarani, R., Shojaeian, A., Palasca, Oana, Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2022, In: Frontiers in Immunology. 13, 21 p., 865777.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Does rapid sequence divergence preclude RNA structure conservation in vertebrates?

    Seemann, Ernst Stefan, Mirza, A. H., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Workman, C. T., Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan & Ruzzo, W. L., 2022, In: Nucleic Acids Research. 50, 5, p. 2452-2463 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes

    Wegeberg, A. M., Okdahl, T., Riahi, S., Ejskjaer, N., Pociot, Flemming, Størling, Joachim, Brock, Birgitte & Brock, C., 2022, In: Cardiovascular Diabetology. 21, 1, 10 p., 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Extracellular Vesicle Therapy for Type 1 Diabetes

    Soltani, S., Mansouri, K., Emami Aleagha, M. S., Moasefi, N., Yavari, Niloofar, Shakouri, S. K., Notararigo, S., Shojaeian, A., Pociot, Flemming & Yarani, R., 2022, In: Frontiers in Immunology. 13, 865782.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Genetic Variants Associated with Neuropeptide Y Autoantibody Levels in Newly Diagnosed Individuals with Type 1 Diabetes

    Mansachs, S. J., Villumsen, S. O., Johannesen, Jesper, Lind, A., Kaur, S. & Pociot, Flemming, 2022, In: Genes. 13, 5, 869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci

    Hajdarevic, R., Lande, A., Mehlsen, J., Rydland, A., Sosa, D. D., Strand, E. B., Mella, O., Pociot, Flemming, Fluge, Ø., Lie, B. A. & Viken, M. K., 2022, In: Brain, Behavior, and Immunity. 102, p. 362-369 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    High-Throughput Human Complement C3 N-Glycoprofiling Identifies Markers of Early Onset Type 1 Diabetes Mellitus in Children

    Šoić, D., Keser, T., Štambuk, J., Kifer, D., Pociot, Flemming, Lauc, G., Morahan, G., Novokmet, M. & Gornik, O., 2022, In: Molecular and Cellular Proteomics. 21, 10, 100407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Low-grade inflammation in type 2 diabetes: A cross-sectional study from a Danish diabetes outpatient clinic

    Okdahl, T., Wegeberg, A. M., Pociot, Flemming, Brock, Birgitte, Størling, Joachim & Brock, C., 2022, In: BMJ Open. 12, 12, 10 p., e062188.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    PDE12 in type 1 diabetes

    Tekin, H., Josefsen, K., Krogvold, L., Dahl-Jørgensen, K., Gerling, I., Pociot, Flemming & Buschard, K., 2022, In: Scientific Reports. 12, 18149.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes

    Al-Sari, N., Kutuzova, Svetlana, Suvitaival, T., Henriksen, P., Pociot, Flemming, Rossing, Peter, McCloskey, D. & Legido-Quigley, C., 2022, In: EBioMedicine. 80, 104032.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells

    Kaur, S., Frørup, C., Mirza, A. H., Fløyel, T., Yarani, R., Colli, M. L., Johannesen, Jesper, Størling, Joachim, Eizirik, D. L. & Pociot, Flemming, 2022, In: Non-coding RNA. 8, 5, 19 p., 69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Reference serum percentile values of adiponectin, leptin, and adiponectin/leptin ratio in healthy Danish children and adolescents

    Hamann, T. V., Mørk, F. C. B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Heidemann, M. S., Schou, A. J., Mølgaard, Christian, Pociot, Flemming, Wedderkopp, N. & Johannesen, Jesper, 2022, In: Scandinavian Journal of Clinical and Laboratory Investigation. 82, 4, p. 267-276 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The effect of saffron supplementation on glycemic parameters: An overview of systematic reviews

    Sadigi, B., Yarani, R., Mirghafourvand, M., Travica, N., Yousefi, Z., Shakouri, S. K., Ostadrahimi, A., Mobasseri, M., Pociot, Flemming, Sanaie, S. & Araj-Khodaei, M., 2022, In: Phytotherapy Research. 36, 9, p. 3444-3458 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    The metabolic syndrome is frequent in children and adolescents with type 1 diabetes compared to healthy controls

    Mork, F. B., Madsen, J. O. B., Pilgaard, Kasper Ascanius, Jensen, Andreas Kryger, Klakk, H., Tarp, J., Bugge, A., Heidemann, M., van Hall, Gerrit, Pociot, Flemming, Wedderkopp, N. & Johannesen, Jesper, 2022, In: Pediatric Diabetes. 23, 7, p. 1064-1072 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2021
  30. Published

    Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity

    Pedersen, K., Haupt-Jorgensen, M., Krogvold, L., Kaur, S., Gerling, I. C., Pociot, Flemming, Dahl-Jørgensen, K. & Buschard, K., Aug 2021, In: Diabetologia. 64, 8, p. 1805-1815 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Skap2, a candidate gene for type 1 diabetes, regulates b-cell apoptosis and glycemic control in newly diagnosed patients

    Fløyel, T., Meyerovich, K., Prause, Michala Cecilie Burstein, Kaur, S., Frørup, C., Mortensen, H. B., Nielsen, L. B., Pociot, Flemming, Cardozo, A. K. & Størling, Joachim, 2021, In: Diabetes. 70, 2, p. 464-476 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

    Kaur, S., Mirza, A. H., Overgaard, A. J., Pociot, Flemming & Størling, Joachim, 2021, In: Frontiers in Genetics. 12, 630109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Cathepsin c regulates cytokine-induced apoptosis in β-cell model systems

    Fløyel, T., Frørup, C., Størling, Joachim & Pociot, Flemming, 2021, In: Genes. 12, 11, 1694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post-hoc analysis of a randomized crossover trial

    Al-Sari, N., Schmidt, S., Suvitaival, T., Kim, M., Trošt, K., Ranjan, A. G., Christensen, M. B., Overgaard, A. J., Pociot, Flemming, Nørgaard, Kirsten & Legido-Quigley, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 2, e00213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes

    Robertson, C. C. & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., 2021, In: Nature Genetics. 53, 7, p. 962-971 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Human pathways in animal models: possibilities and limitations

    Doncheva, Nadezhda Tsankova, Palasca, Oana, Yarani, R., Litman, Thomas, Anthon, Christian, Groenen, M. A. M., Stadler, P. F., Pociot, Flemming, Jensen, Lars Juhl & Gorodkin, Jan, 2021, In: Nucleic Acids Research. 49, 4, p. 1859-1871 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Plasma Exosome-Enriched Extracellular Vesicles From Lactating Mothers With Type 1 Diabetes Contain Aberrant Levels of miRNAs During the Postpartum Period

    Frørup, C., Mirza, A. H., Yarani, R., Nielsen, L. B., Mathiesen, Elisabeth, Damm, Peter, Svare, J., Engelbrekt, C., Størling, Joachim, Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Kaur, S., 2021, In: Frontiers in Immunology. 12, 744509.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2020
  39. Published

    Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives

    Rasouli, H., Yarani, R., Pociot, Flemming & Popović-Djordjević, J., May 2020, In: Pharmacological Research. 155, 15 p., 104723.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Svensson, Jannet, Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 2, p. 366-376 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Characterization of plasma lipidomics in adolescent subjects with increased risk for type 1 diabetes in the DiPiS cohort

    Andersson Svärd, A., Kaur, S., Trôst, K., Suvitaival, T., Lernmark, Å., Maziarz, M., Pociot, Flemming, Overgaard, A. J. & DiPiS Study Group, D. S. G., 2020, In: Metabolomics : Official journal of the Metabolomic Society. 16, 10, 14 p., 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

    Wegeberg, A. L., Okdahl, T., Fløyel, T., Brock, C., Ejskjaer, N., Riahi, S., Pociot, Flemming, Størling, Joachim & Brock, Birgitte, 2020, In: Mediators of Inflammation. 2020, 10 p., 3590389.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Decreased markers of bone turnover in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Pediatric Diabetes. 21, 3, p. 505-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes

    Okdahl, T., Brock, C., Floyel, T., Wegeberg, A. L., Jakobsen, P. E., Ejskjaer, N., Pociot, Flemming, Brock, Birgitte & Størling, Joachim, 2020, In: Clinical Endocrinology. 93, 4, p. 419-428

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Lipidomics of human adipose tissue reveals diversity between body areas

    Al-Sari, N., Suvitaival, T., Mattila, I., Ali, A., Ahonen, L., Trost, K., Henriksen, T. F., Pociot, Flemming, Dragsted, Lars Ove & Legido-Quigley, C., 2020, In: P L o S One. 15, 6, 15 p., e0228521.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Long Noncoding RNAs in Diabetes and β-Cell Regulation

    Kaur, S., Frørup, C., Jensen, V. H., Mirza, A. H., de Melo, J. M. L., Yarani, R., Overgaard, A. J., Størling, J. & Pociot, Flemming, 2020, The Chemical Biology of Long Noncoding RNAs: RNA Technologies. Jurga, S. & Barciszewski, J. (eds.). Springer, Vol. 11. p. 523-544

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  47. Published

    Systemic TNF alpha correlates with residual beta-cell function in children and adolescents newly diagnosed with type 1 diabetes

    Overgaard, A. J., Madsen, J. O. B., Pociot, Flemming, Johannesen, Jesper & Størling, Joachim, 2020, In: BMC Pediatrics. 20, 1, 6 p., 446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The Rac2 GTPase contributes to cathepsin H-mediated protection against cytokine-induced apoptosis in insulin-secreting cells

    Floyel, T., Mirza, A. H., Kaur, S., Frorup, C., Yarani, R., Størling, Joachim & Pociot, Flemming, 2020, In: Molecular and Cellular Endocrinology. 518, 11 p., 110993.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Unaffected bone mineral density in Danish children and adolescents with type 1 diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Jensen, Andreas Kryger, Jørgensen, Niklas Rye, Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2020, In: Journal of Bone and Mineral Metabolism. p. 328–337 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2019
  51. Published

    miRNA-27a-3p and miRNA-222-3p as Novel Modulators of Phosphodiesterase 3a (PDE3A) in Cerebral Microvascular Endothelial Cells

    Yasmeen, S., Kaur, S., Mirza, A. H., Larsen, Birger Brodin, Pociot, Flemming & Kruuse, Christina Rostrup, Aug 2019, In: Molecular Neurobiology. 56, 8, p. 5304–5314

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Tu1766 – Dysregulated Lncrnas in Inflammatory Bowel Disease Demonstrate Immune System Related Association Through Guilt-By Association Analysis

    Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 1 May 2019, In: Gastroenterology. 156, 6, p. S-1116 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins

    Thorsen, S. U., Pipper, C. B., Ellervik, Christina, Pociot, Flemming, Kyvsgaard, J. N. & Svensson, Jannet, 2019, In: Nutrients. 11, 3, 12 p., 543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Bone turnover markers in children and adolescents with type 1 diabetes

    Madsen, J. O. B., Jørgensen, N. R., Pociot, Flemming & Johannesen, Jesper, 2019, In: Pediatric Diabetes. 20, 5, p. 510-522

    Research output: Contribution to journalReviewResearchpeer-review

  55. Published

    Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs

    Mirza, A. H., Kaur, S., Nielsen, L. B., Størling, J., Yarani, R., Roursgaard, Martin, Mathiesen, Elisabeth, Damm, Peter, Svare, J., Mortensen, H. B. & Pociot, Flemming, 2019, In: Frontiers in Immunology. 10, p. 2543

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Capturing residual beta cell function in type 1 diabetes

    Pociot, Flemming, 2019, In: Diabetologia. 62, 1, p. 28-32 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

    Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Perinatal Whole Blood Zinc Status and Cytokines, Adipokines, and Other Immune Response Proteins

    Kyvsgaard, J. N., Ellervik, Christina, Lindkvist, E. B., Pipper, C. B., Pociot, Flemming, Svensson, Jannet & Thorsen, S. U., 2019, In: Nutrients. 11, 11 p., 1980.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Transcriptome landscape of protein-coding genes and long noncoding RNAs in the colon and blood of DSS-induced mouse model of Acute ulcerative colitis

    Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Litman, Thomas, Holmskov, U., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2019, In: Journal of Crohn's and Colitis. 13, p. S129-S130

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  60. 2018
  61. Published

    MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

    Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells

    Nielsen, K. O., Mirza, A. H., Kaur, S., Jacobsen, K. S., Winther, T. N., Glebe, D., Pociot, Flemming, Høgh, Birthe & Størling, J., 15 Sep 2018, In: Experimental Cell Research. 370, 2, p. 399-408 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    25-hydroxyvitamin D, autoantigenic and total antibody concentrations: Results from a Danish case-control study of newly diagnosed patients with childhood type 1 diabetes and their healthy siblings

    Thorsen, S. U., Pipper, C. B., Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2018, In: Scandinavian Journal of Immunology. 87, 1, p. 46-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Abnormal islet sphingolipid metabolism in type 1 diabetes

    Holm, L. J., Krogvold, L., Hasselby, Jane Preuss, Kaur, S., Claessens, L. A., Russell, M. A., Mathews, C. E., Hanssen, K. F., Morgan, N. G., Koeleman, B. P. C., Roep, B. O., Gerling, I. C., Pociot, Flemming, Dahl-Jørgensen, K. & Buschard, K., 2018, In: Diabetologia. 61, 7, p. 1650-1661 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Bone Mineral Density Is Increased in 276 Danish Children and Adolescents with Type-1-Diabetes

    Madsen, J. O. B., Herskin, C. W., Zerahn, B., Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2018, ESPE Abstracts. Bioscientifica, Vol. 89. p. 113 (Hormone Research in Paediatrics).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  66. Published

    Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets

    Kaur, S., Mirza, A. H. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 20 p., 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model

    Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes

    Samandari, N., Mirza, A. H., Kaur, S., Hougaard, P., Nielsen, L. B., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 12 p., 35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Plasma lipid species at type 1 diabetes onset predict residual beta-cell function after 6 months

    Overgaard, A. J., Weir, J. M., Jayawardana, K., Mortensen, H. B., Pociot, Flemming & Meikle, P. J., 2018, In: Metabolomics. 14, 12, 9 p., 158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The emerging role of lncrnas in inflammatory bowel disease

    Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 2018, In: Experimental and Molecular Medicine. 50, p. 1-14 161.

    Research output: Contribution to journalReviewResearchpeer-review

  71. Published

    miRNAs regulate development and function of regulatory T-cells in recent onset islet autoimmunity in pre-Type 1 diabetes

    Kaur, S. & Pociot, Flemming, 2018, In: Non-Coding RNA Investigation. 2, 5 p., 16.

    Research output: Contribution to journalEditorialResearch

  72. 2017
  73. Published

    Levels of soluble TREM-1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case-control study

    Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Skogstrand, K., Pociot, Flemming, Johannesen, Jesper, Svensson, Jannet & the Danish Childhood Diabetes Register, T. D. C. D. R., Dec 2017, In: Pediatric Diabetes. 18, 8, p. 749–754

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Type 1 diabetes genome-wide association studies: Not to be lost in translation

    Pociot, Flemming, Dec 2017, In: Clinical and Translational Immunology. 6, 12, 7 p., e162.

    Research output: Contribution to journalReviewResearchpeer-review

  75. Published

    Long non-coding RNAs as novel players in β cell function and type 1 diabetes

    Mirza, A. H., Kaur, S. & Pociot, Flemming, 24 Jul 2017, In: Human Genomics (Online). 11, 10 p., 17.

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts

    Thorsen, S., Pipper, C., Skogstrand, K., Pociot, Flemming & Svensson, Jannet, Apr 2017, In: Nutrients. 9, 4, 10 p., 365.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years

    Sandahl, K., Nielsen, L. B., Svensson, Jannet, Johannesen, Jesper, Pociot, Flemming, Mortensen, H. B., Hougaard, P., Broe, R., Rasmussen, M. L., Grauslund, J., Peto, T. & Olsen, B. S., Mar 2017, In: Diabetic Medicine. 34, 3, p. 380–386

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis

    Størling, J. & Pociot, Flemming, 16 Feb 2017, In: Genes. 8, 2, 12 p., 72.

    Research output: Contribution to journalReviewResearchpeer-review

  79. Published

    Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study

    Thorsen, S. U., Pipper, C. B., Eising, S., Skogstrand, K., Hougaard, D. M., Svensson, Jannet & Pociot, Flemming, Jan 2017, In: Clinical Immunology. 174, p. 18–23 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus

    Samandari, N., Mirza, A. H., Nielsen, L. B., Kaur, S., Hougaard, P., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2017, In: Diabetologia. 60, 2, p. 354-363

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    High neonatal blood iron content is associated with the risk of childhood type 1 diabetes mellitus

    Kyvsgaard, J. N., Overgaard, A. J., Thorsen, S. U., Hansen, Thomas Hesselhøj, Pipper, C. B., Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2017, In: Nutrients. 9, 11, 10 p., 1221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Low perinatal zinc status is not associated with the risk of type 1 diabetes in children

    Kyvsgaard, J. N., Overgaard, A. J., Jacobsen, L. D., Thorsen, S. U., Pipper, C. B., Hansen, Thomas Hesselhøj, Husted, Søren, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2017, In: Pediatric Diabetes. 18, 7, p. 637–642 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

    Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts

    Kang, W., Bang-Berthelsen, C. H., Holm, A., Houben, A. J. S., Müller, A. H., Thymann, Thomas, Pociot, Flemming, Estivill, X. & Friedländer, M. R., 2017, In: RNA. 23, 4, p. 433-445 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  85. Published

    The Role of an iNOS Polymorphism at the Post-Diagnosis Diabetes Development in Children with Type 1 Diabetes

    Johannesen, J., Eriksen, V., Andersen, M. L. M., Nielsen, L. B., Svensson, Jannet, Bergholdt, R., Pociot, Flemming & Mortensen, H. B., 2017, In: Journal of Endocrinology and Diabetes Research . 2, 2, 5 p., 100114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    The identification and functional annotation of RNA structures conserved in vertebrates

    Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. 2016
  88. Published

    Metabolomic Biomarkers in the Progression to Type 1 Diabetes

    Overgaard, A. J., Kaur, S. & Pociot, Flemming, Dec 2016, In: Current Diabetes Reports. 16, 5 p., 127.

    Research output: Contribution to journalReviewResearchpeer-review

  89. Published

    GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation

    Bang-Berthelsen, C. H., Holm, T. L., Pyke, C., Simonsen, L., Søkilde, R., Pociot, Flemming, Heller, R. S., Folkersen, L., Kvist, P. H., Jackerott, M., Fleckner, J., Vilien, M., Knudsen, L. B., Heding, A. & Frederiksen, K. S., Sep 2016, In: Inflammatory Bowel Diseases. 22, 9, p. 2078-97 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Neonatal vitamin D status is not associated with later risk of type 1 diabetes: results from two large Danish population-based studies

    Jacobsen, Ramune, Thorsen, S. U., Cohen, A. S., Lundqvist, M., Frederiksen, P., Pipper, C. B., Pociot, Flemming, Thygesen, L. C., Ascherio, A., Svensson, Jannet & Heitmann, Berit, Sep 2016, In: Diabetologia. 59, 9, p. 1871-1881 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Potential beneficial effects of a gluten-free diet in newly diagnosed children with type 1 diabetes: a pilot study

    Svensson, Jannet, Sildorf, S. M., Pipper, C. B., Kyvsgaard, J. N., Bøjstrup, J., Pociot, Flemming, Mortensen, H. B. & Buschard, K., 7 Jul 2016, In: SpringerPlus. 5, 8 p., 994.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Effects of the genome on immune regulation in type 1 diabetes

    Pociot, Flemming, Kaur, S. & Nielsen, L. B., Jul 2016, In: Pediatric Diabetes. 17 , S22, p. 37-42 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Genetic risk factors for type 1 diabetes

    Pociot, Flemming & Lernmark, Å., Jun 2016, In: The Lancet. 387, 10035, p. 2331-9 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  94. Published

    MicroRNAs as regulators of beta-cell function and dysfunction

    Osmai, M., Osmai, Y., Bang-Berthelsen, C. H., Pallesen, E. M. H., Vestergaard, A. L., Novotny, G. W., Pociot, Flemming & Mandrup-Poulsen, Thomas, May 2016, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 4, p. 334–349 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line

    Jacobsen, K. S., Nielsen, K. O., Nordmann Winther, T., Glebe, D., Pociot, Flemming & Høgh, Birthe, 22 Jan 2016, In: BMC Research Notes. 9, p. 1-7 7 p., 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus

    Kaur, S., Mirza, A. H., Brorsson, C. A., Fløyel, T., Størling, Joachim, Mortensen, H. B., Pociot, Flemming & Hvidoere International Study Group, H. I. S. G., 5 Jan 2016, In: Molecular and Cellular Endocrinology. 419, p. 83-91 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes

    Fukaya, M., Brorsson, C. A., Meyerovich, K., Catrysse, L., Delaroche, D., Vanzela, E. C., Ortis, F., Beyaert, R., Nielsen, L. B., Andersen, M. L. M., Mortensen, H. B., Pociot, Flemming, van Loo, G., Størling, J. & Cardozo, A. K., Jan 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 48-61 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis

    Overgaard, A. J., Weir, J. M., De Souza, D. P., Tull, D., Haase, C., Meikle, P. J. & Pociot, Flemming, Jan 2016, In: Metabolomics. 12, p. 1-9 9 p., 13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells

    Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.

    Research output: Contribution to journalComment/debateResearchpeer-review

  100. Published

    Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control

    Brorsson, C. A., Nielsen, L. B., Andersen, M., Kaur, S., Bergholdt, R., Hansen, L., Mortensen, H. B., Pociot, Flemming, Størling, J. & Hvidoere Study Group On Childhood Diabetes, H. S. G. O. C. D., 2016, In: Journal of Diabetes Research. 2016, 8 p., 9570424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study

    Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Pociot, Flemming, Johannesen, Jesper & Svensson, Jannet, 2016, In: International Journal of Endocrinology. 2016, 7 p., 8350158.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Systematic evaluation of genes and genetic variants associated with type 1 diabetes susceptibility

    Ram, R., Mehta, M., Nguyen, T. Q., Larma, I., Boehm, B. O., Pociot, Flemming, Concannon, P. & Morahan, G., 2016, In: Journal of Immunology. 196, 7, p. 3043-3053 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. 2015
  104. Published

    Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study

    Witsø, E., Cinek, O., Tapia, G., Brorsson, C. A., Stene, L. C., Gjessing, H. K., Rasmussen, T., Bergholdt, R., Pociot, Flemming & Rønningen, K. S., Dec 2015, In: Viral Immunology. 28, 10, p. 556-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells

    Marroqui, L., Dos Santos, R. S., Fløyel, T., Grieco, F. A., Santin, I., Op de Beeck, A., Marselli, L., Marchetti, P., Pociot, Flemming & Eizirik, D. L., Nov 2015, In: Diabetes. 64, 11, p. 3808-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Genes affecting β-cell function in type 1 diabetes

    Fløyel, T., Kaur, S. & Pociot, Flemming, Nov 2015, In: Current Diabetes Reports. 15, 11, p. 1-11 15-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987)

    Thorsen, S. U., Sandahl, K., Nielsen, L. B., Broe, R., Rasmussen, M. L., Peto, T., Grauslund, J., Andersen, M. L. M., Mortensen, H. B., Pociot, Flemming, Olsen, B. S. & Brorsson, C., Nov 2015, In: Graefe's Archive for Clinical and Experimental Ophthalmology. 253, 11, p. 1959-65 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Shared Genetic Basis for Type 1 Diabetes, Islet Autoantibodies, and Autoantibodies Associated With Other Immune-Mediated Diseases in Families With Type 1 Diabetes

    Brorsson, C. A., Pociot, Flemming & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., Oct 2015, In: Diabetes Care. 38, Suppl 2, p. S8-S13

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

    Brorsson, C. A., Onengut, S., Chen, W., Wenzlau, J., Yu, L., Baker, P., Williams, A. J. K., Bingley, P. J., Hutton, J. C., Eisenbarth, G. S., Concannon, P., Rich, S. S., Pociot, Flemming & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., Aug 2015, In: Diabetes. 64, 8, p. 3017-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Residual β-cell function and the insulin-like growth factor system in Danish children and adolescents with type 1 diabetes

    Sorensen, J. S., Birkebaek, N. H., Bjerre, M., Pociot, Flemming, Kristensen, K., Hoejberg, A. S., Frystyk, J. & Danish Society for Diabetes in Childhood and Adolescence, D. S. F. D. I. C. A. A., Mar 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 3, p. 1053-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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