Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

Publication year:
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1 - 50 out of 203Page size: 50
  1. 2024
  2. Published

    Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry

    Bock, F., Dong, X., Li, S., Viquez, O. M., Sha, E., Tantengco, M., Hennen, E. M., Plosa, E., Ramezani, A., Brown, K. L., Whang, Y. M., Terker, A. S., Arroyo, J. P., Harrison, D. G., Fogo, A., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2024, In: Science Advances. 10, 6, eadi7840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    A RhoA-mediated biomechanical response in Schwann cells modulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2023, In: Progress in Neurobiology. 227, 13 p., 102481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

    Martínez-Sánchez, L. D. C., Ngo, P. A., Pradhan, R., Becker, L-S., Boehringer, D., Soteriou, D., Kubankova, M., Schweitzer, C., Koch, T., Thonn, V., Erkert, L., Stolzer, I., Günther, C., Becker, C., Weigmann, B., Klewer, M., Daniel, C., Amann, K., Tenzer, S., Atreya, R. & 8 others, Bergo, M., Brakebusch, Cord Herbert, Watson, A. J. M., Guck, J., Fabry, B., Atreya, I., Neurath, M. F. & López-Posadas, R., 2023, In: Gut. 72, 2, p. 275-294 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

    Socodato, R., Almeida, T. O., Portugal, C. C., Santos, E. C. S., Tedim-Moreira, J., Galvão-Ferreira, J., Canedo, T., Baptista, F. I., Magalhães, A., Ambrósio, A. F., Brakebusch, Cord Herbert, Rubinstein, B., Moreira, I. S., Summavielle, T., Pinto, I. M. & Relvas, J. B., 2023, In: Cell Reports. 42, 12, 28 p., 113447.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    RhoB promotes Salmonella survival by regulating autophagy

    Kirchenwitz, M., Halfen, J., von Peinen, K., Prettin, S., Kollasser, J., zur Lage, S., Blankenfeldt, W., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, In: European Journal of Cell Biology. 102, 4, 17 p., 151358.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    RhoB promotesSalmonellasurvival by regulating autophagy

    Kirchenwitz, M., Halfen, J., Peinen, K. V., Prettin, S., Kollasser, J., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, bioRxiv, 52 p.

    Research output: Working paper › Preprint › Research

  9. Published

    Two Transient Receptor Potential Channels at Focal Adhesions

    Mitsou, I., Carlson, C. R., Multhaupt, Hinke Arnolda B V H, Brakebusch, Cord Herbert & Couchman, John Robert, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 9, p. 495-508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2022
  11. Published

    Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo

    Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

    Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Control of cortical cytoskeleton-membrane interaction by RhoA regulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2022, Cold Spring Harbor Laboratory, 15 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  14. Published

    The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition

    Petersen, L., Stroh, S., Schöttelndreier, D., Grassl, G. A., Rottner, K., Brakebusch, Cord Herbert, Fahrer, J. & Genth, H., 2022, In: Frontiers in Microbiology. 13, 11 p., 846215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells

    Vadakumchery, A., Faraidun, H., Ayoubi, O. E., Outaleb, I., Schmid, V., Abdelrasoul, H., Amendt, T., Khadour, A., Setz, C., Göhring, K., Lodd, K., Hitzing, C., Alkhatib, A., Bilal, M., Benckendorff, J., Al Shugri, A. K., Brakebusch, C. H., Engels, N., Datta, M., Hobeika, E. & 2 others, Alsadeq, A. & Jumaa, H., 2022, In: Frontiers in Immunology. 13, 19 p., 842340.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2021
  17. Published

    ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Brandao, R., Kwa, M. Q., Yarden, Y. & Brakebusch, Cord Herbert, 2021, In: FEBS Open Bio. 11, 6, p. 1579-1592 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells

    Xu, L., Zu, T., Li, T., Li, M., Mi, J., Bai, F., Liu, G., Wen, J., Li, H., Brakebusch, Cord Herbert, Wang, X. & Wu, X., 2021, In: PLOS Genetics. 17, 2, p. 1-25 e1009283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Analyzing skin tumor development in mice by the DMBA/TPA model

    Li, H. & Brakebusch, Cord Herbert, 2021, Carcinogen-driven mouse models of oncogenesis. Galluzzi, L. & Buqué, A. (eds.). Elsevier, Vol. 163. p. 113-121 9 p. (Methods in Cell Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  20. Published

    CRISPR Genome Editing: How to Make a Fantastic Method Even Better

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-2 408.

    Research output: Contribution to journal › Editorial › Research › peer-review

  21. Published

    MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model

    Kwa, M. Q., Brandao, R., Phung, T. H., Ge, J., Scieri, G. & Brakebusch, Cord Herbert, 2021, In: Cells. 10, 4, 942.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity

    Bock, F., Elias, B. C., Dong, X., Parekh, D. V., Mernaugh, G., Viquez, O. M., Hassan, A., Amara, V. R., Liu, J., Brown, K. L., Terker, A. S., Chiusa, M., Gewin, L. S., Fogo, A. B., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2021, In: Journal of Cell Biology. 220, 11, 28 p., e202103080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-3 401.

    Research output: Contribution to journal › Editorial › Research › peer-review

  24. Published

    RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury

    Stern, S., Hilton, B. J., Burnside, E. R., Dupraz, S., Handley, E. E., Gonyer, J. M., Brakebusch, Cord Herbert & Bradke, F., 2021, In: Neuron. 109, 21, p. 3436-3455 30 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

    Heib, T., Hermanns, H. M., Manukjan, G., Englert, M., Kusch, C., Becker, I. C., Gerber, A., Wackerbarth, L. M., Burkard, P., Dandekar, T., Balkenhol, J., Jahn, D., Beck, S., Meub, M., Dütting, S., Stigloher, C., Sauer, M., Cherpokova, D., Schulze, H., Brakebusch, C. & 3 others, Nieswandt, B., Nagy, Z. & Pleines, I., 2021, In: Cell Reports. 35, 6, p. 109102 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2020
  27. Published

    Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

    Bischoff, N., Wimberger, S., Maresca, M. & Brakebusch, Cord Herbert, 2020, In: Cells. 9, 5

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

    Gilles, G., McCulloch, A. D., Brakebusch, Cord Herbert & Herum, K. M., 2020, In: PLoS ONE. 15, 10, p. 1-13 e0241390.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

    Socodato, R., Portugal, C. C., Canedo, T., Rodrigues, A., Almeida, T. O., Henriques, J. F., Vaz, S. H., Magalhães, J., Silva, C. M., Baptista, F. I., Alves, R. L., Coelho-Santos, V., Silva, A. P., Paes-de-Carvalho, R., Magalhães, A., Brakebusch, Cord Herbert, Sebastião, A. M., Summavielle, T., Ambrósio, A. F. & Relvas, J. B., 2020, In: Cell Reports. 31, 12, p. 1-29 107796.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    PATHBIO: an international training program for precision mouse phenotyping

    Ruberte, J., Schofield, P. N., Brakebusch, Cord Herbert, Vogel, P., Herault, Y., Gracia, G., McKerlie, C., Hrabĕ de Angelis, M., Hagn, M. & Sundberg, J. P., 2020, In: Mammalian Genome. 31, p. 49-53

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

    Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, Cord Herbert, McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020, In: Journal of the American Heart Association. 9, 3, 31 p., e013518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway

    Zu, T., Wen, J., Xu, L., Li, H., Mi, J., Brakebusch, Cord Herbert, Fisher, D. E. & Wu, X., 2020, In: Frontiers in Oncology. 10, 15 p., 624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2019
  34. Published

    Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 26 Nov 2019, In: Scientific Reports. 9, 1, p. 18008 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  35. Published

    RhoA Controls Axon Extension Independent of Specification in the Developing Brain

    Dupraz, S., Hilton, B. J., Husch, A., Santos, T. E., Coles, C. H., Stern, S., Brakebusch, Cord Herbert & Bradke, F., 18 Nov 2019, In: Current biology : CB. 29, 22, p. 3874-3886 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice

    López-Posadas, R., Fastancz, P., Martínez-Sánchez, L. D. C., Panteleev-Ivlev, J., Thonn, V., Kisseleva, T., Becker, L. S., Schulz-Kuhnt, A., Zundler, S., Wirtz, S., Atreya, R., Carlé, B., Friedrich, O., Schürmann, S., Waldner, M. J., Neufert, C., Brakebusch, Cord Herbert, Bergö, M. O., Neurath, M. F. & Atreya, I., Nov 2019, In: Gastroenterology. 157, 5, p. 1293-1309 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

    Akula, M. K., Ibrahim, M. X., Ivarsson, E. G., Khan, O. M., Kumar, I. T., Erlandsson, M., Karlsson, C., Xu, X., Brisslert, M., Brakebusch, Cord Herbert, Wang, D., Bokarewa, M., Sayin, V. I. & Bergo, M. O., 4 Sep 2019, In: Nature Communications. 10, 1, p. 1-13 13 p., 3975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Senescence regulation by nuclear N-WASP: a role in cancer?

    Li, H. & Brakebusch, Cord Herbert, Jul 2019, In: Oncoscience. 6, 7-8, p. 354-356 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Negative regulation of p53-induced senescence by N-WASP is crucial for DMBA/TPA-induced skin tumor formation

    Li, H., Petersen, S., Garcia Mariscal, A. & Brakebusch, Cord Herbert, 1 May 2019, In: Cancer Research. 79, 9, p. 2167-2181 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Adgrf5 contributes to patterning of the endothelial deep layer in retina

    Niaudet, C., Petkova, M., Jung, B., Lu, S., Laviña, B., Offermanns, S., Brakebusch, Cord Herbert & Betsholtz, C., 2019, In: Angiogenesis. 22, 4, p. 491-505 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection

    Papareddy, P., Rossnagel, M., Doreen Hollwedel, F., Kilic, G., Veerla, S., Naudin, C., Smeds, E., Westman, J., Martinez-Martinez, I., Egesten, A., de la Morena-Barrio, M. E., Corral, J., Linder, A., Artoni, A., Abbattista, M., Novembrino, C., Brakebusch, Cord Herbert, Martinelli, I., Kasetty, G. & Herwald, H., 2019, In: Nature Microbiology. 4, 12, p. 2442-2455 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression

    Castro, M., Laviña, B., Ando, K., Álvarez-Aznar, A., Abu Taha, A., Brakebusch, Cord Herbert, Dejana, E., Betsholtz, C. & Gaengel, K. B., 2019, In: Circulation Research. 124, 8, p. 1240-1252 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Cancer-associated fibroblasts: how do they contribute to metastasis?

    Kwa, M. Q., Herum, K. M. & Brakebusch, Cord Herbert, 2019, In: Clinical and Experimental Metastasis. 36, 2, p. 71-86

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Rho GTPases in cancer: friend or foe?

    Svensmark, J. H. & Brakebusch, Cord Herbert, 2019, In: Oncogene. 38, p. 7448-7456

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones

    Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.

    Research output: Contribution to journal › Conference article › Research › peer-review

  46. Published

    The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

    Cavaco, A. C. M., Rezaei, M., Caliandro, M. F., Lima, A. M., Stehling, M., Dhayat, S. A., Haier, J., Brakebusch, Cord Herbert & Eble, J. A., 2019, In: Cancers. 11, 1, p. 1-20 20 p., 14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The small GTPase RhoA regulates the onset of myelination and myelin production during PNS development: [Meeting Abstract}

    Seixas, A., Morais, M., Pereira, J. A., Krause, S., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2019, In: Glia. 67, S1, p. E473-E474 T12-052B.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. 2018
  49. Published

    Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations

    Laviña, B., Castro, M., Niaudet, C., Cruys, B., Álvarez-Aznar, A., Carmeliet, P., Bentley, K., Brakebusch, Cord Herbert, Betsholtz, C. & Gaengel, K., 2 Jul 2018, In: Development (Cambridge, England). 145, 13, 20 p., dev161182.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

    García-Mariscal, A., Li, H., Pedersen, E., Peyrollier, K., Ryan, K. M., Stanley, A., Quondamatteo, F. & Brakebusch, Cord Herbert, 15 Feb 2018, In: Oncogene. 37, 7, p. 847-860 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

    Li, H., Yao, Q., Mariscal, A. G., Wu, X., Hülse, J., Pedersen, E., Helin, K., Waisman, A., Vinkel, C., Thomsen, Simon Francis, Avgustinova, A., Benitah, S. A., Lovato, P., Norsgaard, H., Mortensen, M. S., Veng, L., Rozell, B. & Brakebusch, Cord Herbert, 2018, In: Nature Communications. 9, 1, p. 1-18 18 p., 1420.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke

    Karabiyik, C., Fernandes, R., Figueiredo, F. R., Socodato, R., Brakebusch, Cord Herbert, Lambertsen, K. L., Relvas, J. B. & Santos, S. D., 2018, In: Brain Pathology. 28, 4, p. 569-580 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    RhoA Controls Retinoid Signaling by ROCK Dependent Regulation of Retinol Metabolism

    García-Mariscal, A., Peyrollier, K., Basse, A., Pedersen, E. D. K., Rühl, R., van Hengel, J. & Brakebusch, Cord Herbert, 2018, In: Small GTPases. 9, 5, p. 433–444

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

    Manresa-Arraut, A., Johansen, F. F., Brakebusch, Cord Herbert, Issazadeh-Navikas, Shohreh & Hasseldam, Henrik, 2018, In: Frontiers in Immunology. 9, p. 1-14 14 p., 1235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells

    Ge, J., Burnier, L., Adamopoulou, M., Kwa, M. Q., Schaks, M., Rottner, K. & Brakebusch, Cord Herbert, 2018, In: The Journal of Biological Chemistry. 293, 24, p. 9358-9369 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2017
  58. Published

    FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 17 p., 9791.

    Research output: Contribution to journal › Journal article › Research › peer-review

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