Clare Louise Hawkins
Professor MSO
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion
Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael J., Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In: Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?
Ismael, F. O., Barrett, T. J., Sheipouri, D., Brown, B. E., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: P L o S One. 11, 12, 16 p., e0168844.Research output: Contribution to journal › Journal article › Research › peer-review
The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study
Jansson, P. J., Hawkins, Clare Louise, Lovejoy, D. B. & Richardson, D. R., Nov 2010, In: Journal of Inorganic Biochemistry. 104, 11, p. 1224-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ROLE OF EXTRACELLULAR TRAP RELEASE BY MACROPHAGES DURING THE DEVELOPMENT OF CHRONIC INFLAMMATION.
Jensen, M., Hägglund, Per Mårten, Zhang, Y., Rayner, B. & Hawkins, Clare Louise, 2021, In: Atherosclerosis. 331, p. E72-E72 PO51.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers
Jensen, M., Thorsen, N. W., Hallberg, L. A. E., Hägglund, Per Mårten & Hawkins, Clare Louise, 2023, In: Free Radical Biology and Medicine. 202, p. 97-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis
Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael J. & Siebuhr, A. S., 2020, In: Scientific Reports. 10, 1, 10 p., 17300.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides
Kajer, T. B., Fairfull-Smith, K. E., Yamasaki, T., Yamada, K., Fu, S., Bottle, S. E., Hawkins, Clare Louise & Davies, Michael J., May 2014, In: Free Radical Biology & Medicine. 70, p. 96-105 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
β3 Adrenergic Stimulation Restores Nitric Oxide/Redox Balance and Enhances Endothelial Function in Hyperglycemia
Karimi Galougahi, K., Liu, C., Garcia, A., Gentile, C., Fry, N. A., Hamilton, E. J., Hawkins, Clare Louise & Figtree, G. A., 19 Feb 2016, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 5, 2, e002824.Research output: Contribution to journal › Journal article › Research › peer-review
Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations
Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 15 Apr 2010, In: Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages
Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase
Lim, Y. J., Foo, T. C., Yeung, A. W. S., Tu, X., Ma, Y., Hawkins, Clare Louise, Witting, P. K., Jameson, G. N. L., Terentis, A. C. & Thomas, S. R., 2019, In: Biochemistry. 58, 7, p. 974-986Research output: Contribution to journal › Journal article › Research › peer-review
Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells
Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael J. & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid
Lloyd, M. M., van Reyk, D. M., Davies, Michael J. & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity
Lok, H. C., Sahni, S., Jansson, P. J., Kovacevic, Z., Hawkins, Clare Louise & Richardson, D. R., 30 Dec 2016, In: The Journal of Biological Chemistry. 291, 53, p. 27042-27061 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes
Lok, H. C., Suryo Rahmanto, Y., Hawkins, Clare Louise, Kalinowski, D. S., Morrow, C. S., Townsend, A. J., Ponka, P. & Richardson, D. R., 2 Jan 2012, In: The Journal of Biological Chemistry. 287, 1, p. 607-18 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages
Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: Free Radical Biology & Medicine. 94, p. 88-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages
Love, D. T., Guo, C., Nikelshparg, E. I., Brazhe, N. A., Sosnovtseva, Olga & Hawkins, Clare Louise, 2020, In: Redox Biology. 36, 12 p., 101602.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
8-chloroadenosine alters the metabolic profile and downregulates antioxidant and DNA damage repair pathways in macrophages
Macer-Wright, J., Sileikaite, I., Rayner, B. & Hawkins, Clare Louise, 2020, In: Chemical Research in Toxicology. 33, 2, p. 402-413Research output: Contribution to journal › Journal article › Research › peer-review
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A Role for Chlorinated Nucleosides in the Perturbation of Macrophage Function and Promotion of Inflammation
Macer-Wright, J. L., Stanley, N. R., Portman, N., Tan, J. T., Bursill, C., Rayner, B. S. & Hawkins, Clare Louise, 2019, In: Chemical Research in Toxicology. 32, 6, p. 1223-1234Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins
Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New roles of neutrophils and granulocytic MDSC in autoimmune diseases, inflammation, and anti-microbial immunity
Odobasic, D., Hawkins, Clare Louise & Radic, M., 2022, In: Frontiers in Immunology. 13, 2 p., 974062.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid
Pan, G., Rayner, B., Zhang, Y., van Reyk, D. & Hawkins, Clare Louise, 2018, In: Archives of Biochemistry and Biophysics. 642, p. 23-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids
Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 173742266
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
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Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
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