Chuna Ram Choudhary
Professor, Group Leader, Professor
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DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988Research output: Contribution to journal › Journal article › Research › peer-review
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Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-Treated Yeast Cells
Iesmantavicius, V., Weinert, B. T. & Choudhary, Chunaram, 24 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1979-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Avoiding abundance bias in the functional annotation of posttranslationally modified proteins
Schölz, C., Lyon, D., Refsgaard, J. C., Jensen, Lars Juhl, Choudhary, Chunaram & Weinert, B. T., Nov 2015, In: Nature Methods. 12, p. 1003-4 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation
Hansen, B. K., Gupta, R., Baldus, L., Lyon, D., Narita, Takeo, Lammers, M., Choudhary, Chunaram & Weinert, B. T., 2019, In: Nature Communications. 10, 11 p., 1055.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions
Weinert, B. T., Moustafa, T., Iesmantavicius, V., Zechner, R. & Choudhary, Chunaram, 3 Nov 2015, In: E M B O Journal. 34, 21, p. 2620-2632 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry
Prus, Gabriela Zofia, Hoegl, A., Weinert, B. T. & Choudhary, Chunaram, 2019, In: Trends in Biochemical Sciences. 44, 11, p. 943-960Research output: Contribution to journal › Review › Research › peer-review
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Acetylation site specificities of lysine deacetylase inhibitors in human cells
Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, Lars Juhl, Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, Chunaram, 2015, In: Nature Biotechnology. 33, p. 415–423Research output: Contribution to journal › Journal article › Research › peer-review
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Acetylation of intrinsically disordered regions regulates phase separation
Saito, M., Hess, D., Eglinger, J., Fritsch, A. W., Kreysing, M., Weinert, B. T., Choudhary, Chunaram & Matthias, P., Jan 2019, In: Nature Chemical Biology. 15, 1, p. 51-61Research output: Contribution to journal › Journal article › Research › peer-review
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Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes
Narita, Takeo, Higashijima, Y., Kilic, Sinan, Liebner, Tim, Walter, Jonas & Choudhary, Chunaram, 2023, In: Nature Genetics. 55, p. 679-692Research output: Contribution to journal › Journal article › Research › peer-review
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Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae
Weinert, B. T., Iesmantavicius, V., Moustafa, T., Schölz, C., Wagner, S. A., Magnes, C., Zechner, R. & Choudhary, Chunaram, 31 Jan 2014, In: Molecular Systems Biology. 10, 1, p. 716 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli
Weinert, B. T., Iesmantavicius, V., Wagner, S. A., Schölz, C., Gummesson, Bertil, Beli, P., Nyström, T. & Choudhary, Chunaram, 25 Jul 2013, In: Molecular Cell. 51, 2, p. 265-272 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli acetylome
Weinert, B. T., Satpathy, S., Hansen, B. K., Lyon, D., Jensen, Lars Juhl & Choudhary, Chunaram, May 2017, In: Molecular and Cellular Proteomics. 16, p. 759-769Research output: Contribution to journal › Journal article › Research › peer-review
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A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response
Blasius, M., Wagner, S. A., Choudhary, Chunaram, Bartek, J. & Jackson, S. P., 4 Sep 2014, In: Genes & Development. 28, 18, p. 1977-1982 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1
Blasius, M., Forment, J. V., Thakkar, N., Wagner, S. A., Choudhary, Chunaram & Jackson, S. P., 2011, In: Genome Biology (Online Edition). 12, 8, p. R78Research output: Contribution to journal › Journal article › Research › peer-review
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A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis
Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040Research output: Contribution to journal › Journal article › Research › peer-review
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A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles
Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chunaram, 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284Research output: Contribution to journal › Journal article › Research › peer-review
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A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex
Starnes, L. M., Su, D., Pikkupeura, L. M., Weinert, B. T., Santos, M. A., Mund, A., Soria, R., Cho, Y-W., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J-E., Peng, W., Yuan, J., Ge, K., Montoya, G., Nussenzweig, A., Choudhary, C. R. & 1 others, , 15 Jan 2016, In: Genes & Development. 30, 2, p. 149-163 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13781159
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Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
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Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover
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Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
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