Chuna Ram Choudhary

Chuna Ram Choudhary

professor, group leader

  • Choudhary Group

    Blegdamsvej 3, 2200 København N., Bygning 6, Building: 06-6-14

    Phone: +45 35 32 50 20Mobile: +45 24 42 66 43

  1. Published

    Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

    Lasko, L. M., Jakob, C. G., Edalji, R. P., Qiu, W., Montgomery, D., Digiammarino, E. L., Hansen, T. M., Risi, R. M., Frey, R., Manaves, V., Shaw, B., Algire, M., Hessler, P., Lam, L. T., Uziel, T., Faivre, E., Ferguson, D., Buchanan, F. G., Martin, R. L., Torrent, M., Chiang, G. G., Karukurichi, K., Langston, J. W., Weinert, B. T., Choudhary, Chuna Ram, de Vries, P., Van Drie, J. H., McElligott, D., Kesicki, E., Marmorstein, R., Sun, C., Cole, P. A., Rosenberg, S. H., Michaelides, M. R., Lai, A. & Bromberg, K. D., 5 Oct 2017, In : Nature. 550, 7674, p. 128-132 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Functions and mechanisms of non-histone protein acetylation

    Narita, Takeo, Weinert, B. T. & Choudhary, Chuna Ram, 2019, In : Nature Reviews. Molecular Cell Biology. 20, p. 156-174 19 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    HBO1 is required for the maintenance of leukaemia stem cells

    MacPherson, L., Anokye, J., Yeung, M. M., Lam, E. Y. N., Chan, Y., Weng, C., Yeh, P., Knezevic, K., Butler, M. S., Hoegl, A., Chan, K., Burr, M. L., Gearing, L. J., Willson, T., Liu, J., Choi, J., Yang, Y., Bilardi, R. A., Falk, H., Nghi Nguyen, Stupple, P. A., Peat, T. S., Zhang, M., De Silva, M., Carrasco-Pozo, C., Avery, V. M., Khoo, S., Dolezal, O., Dennis, M. L., Nuttall, S., Surjadi, R., Newman, J., Ren, B., Leaver, D. J., Sun, Y., Baell, J. B., Dovey, O., Vassiliou, G. S., Grebien, F., Dawson, S., Street, I. P., Monahan, B. J., Burns, C. J., Choudhary, Chuna Ram, Blewitt, M. E., Voss, A. K., Thomas, T. & Dawson, M. A., 2020, In : Nature. 577, 7789, p. 266-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation

    Khoa, L. T. P., Tsan, Y., Mao, F., Kremer, D. M., Sajjakulnukit, P., Zhang, L., Zhou, B., Tong, X., Bhanu, N. V., Choudhary, Chuna Ram, Garcia, B. A., Yin, L., Smith, G. D., Saunders, T. L., Bielas, S. L., Lyssiotis, C. A. & Dou, Y., 24 Jun 2020, In : Cell Stem Cell.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chuna Ram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In : Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  6. Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML)

    Kindler, T., Breitenbuecher, F., Kasper, S., Estey, E., Giles, F., Feldman, E., Ehninger, G., Schiller, G., Klimek, V., Nimer, S. D., Gratwohl, A., Choudhary, Chuna Ram, Mueller-Tidow, C., Serve, H., Gschaidmeier, H., Cohen, P. S., Huber, C. & Fischer, T., 2005, In : Blood. 105, 1, p. 335-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Lysine acetylation targets protein complexes and co-regulates major cellular functions

    Choudhary, Chuna Ram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In : Science. 325, 5942, p. 834-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

    Weinert, B. T., Schölz, C., Wagner, S. A., Iesmantavicius, V., Su, D., Daniel, J. A. & Choudhary, Chuna Ram, 29 Aug 2013, In : Cell Reports. 4, 4, p. 842-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

    Choudhary, Chuna Ram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In : Molecular Cell. 36, 2, p. 326-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance

    Pinela da Silva, S. C., Altmannova, V., Luke-Glaser, S., Henriksen, P., Gallina, Irene, Yang, X., Choudhary, Chuna Ram, Luke, B., Krejci, L. & Lisby, Michael, 2016, In : Genes & Development. 30, 6, p. 700-717 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13781159