Christoffer Clemmensen

Christoffer Clemmensen

Associate Professor


  1. 2024
  2. Published

    An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity

    Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Atlas of exercise-induced brain activation in mice

    Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. Published

    Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

    Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. 2023
  8. Published

    Cross-species comparison of pregnancy-induced GDF15

    Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Do psychedelics have therapeutic potential for obesity?

    Fadahunsi, N., Knudsen, Gitte Moos & Clemmensen, Christoffer, 2023, In: Nature Reviews Endocrinology. 19, p. 1-2

    Research output: Contribution to journalComment/debateResearch

  11. Published
  12. Published

    GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism

    Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity

    Falk, S., Petersen, Jonas Odgaard, Svendsen, C. S. A., Leguizamon, Cesar Ramon Romero, Jørgensen, Søren Heide, Krauth, Nathalie, Ludwig, M. Q., Jørgensen, Kathrine Lundø, Roostalu, U., Hjort-Gregersen, G. S., Nielsen, D. A. G., Ejdrup, Aske Lykke, Pers, Tune H, Dmytriyeva, O., Hecksher-Soerensen, J., Gether, Ulrik, Kohlmeier, Kristi Anne & Clemmensen, Christoffer, 2023, In: Cell Reports. 42, 5, 18 p., 112466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journalComment/debateResearch

  16. Published

    Ketone monoester increases circulating levels of LEAP2 and decreases appetite in healthy men

    Holm, Stephanie Kjærulff, Vestergaard, E. T., Zubanovic, N. B., Byberg, Sarah, Clemmensen, Christoffer, Holst, Birgitte & Thomsen, H. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 7, p. :2023–2027

    Research output: Contribution to journalLetterResearchpeer-review

  17. Published

    Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice

    Rial-Pensado, E., Canaple, L., Guyot, R., Clemmensen, Christoffer, Wiersema, J., Wu, S., Richard, S., Boelen, A., Müller, T. D., López, M., Flamant, F. & Gauthier, K., 2023, In: Endocrinology. 164, 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Overlooked confounding in studies of metabolite salts

    Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.

    Research output: Contribution to journalComment/debateResearch

  19. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.

    Research output: Working paperPreprintResearch

  22. Published

    Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

    Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, Kahkoska, A. R., Kettunen, J. L. T., Kreienkamp, R. J., Lim, L. L., Männistö, J. M. E., Massey, R., Mclennan, N. M., Miller, R. G., Morieri, M. L., Most, J., Naylor, R. N., Ozkan, B., Patel, K. A., Pilla, S. J., Prystupa, K., Raghavan, S., Rooney, M. R., Schön, M., Semnani-Azad, Z., Sevilla-Gonzalez, M., Svalastoga, P., Takele, W. W., Tam, C. H. T., Thuesen, Anne Cathrine Baun, Tosur, M., Wallace, A. S., Wang, C. C., Wong, J. J., Yamamoto, J. M., Young, K., Amouyal, C., Lepola, Mette Andersen, Bonham, M. P., Chen, M., Cheng, F., Chikowore, T., Chivers, S. C., Clemmensen, Christoffer, Dabelea, D., Dawed, A. Y., Deutsch, A. J., Dickens, L. T., DiMeglio, L. A., Dudenhöffer-Pfeifer, M., Evans-Molina, C., Fernández-Balsells, M. M., Fitipaldi, H., Fitzpatrick, S. L., Gitelman, S. E., Goodarzi, M. O., Grieger, J. A., Guasch Ferre, Marta, Habibi, N., Hansen, Torben, Huang, C., Harris-Kawano, A., Ismail, H. M., Hoag, B., Johnson, R. K., Jones, A. G., Koivula, R. W., Leong, A., Leung, G. K. W., Libman, I. M., Liu, K., Long, S. A., Lowe, W. L., Morton, R. W., Motala, A. A., Onengut-Gumuscu, S., Pankow, J. S., Pathirana, M., Pazmino, S., Perez, D., Petrie, J. R., Powe, C. E., Quinteros, A., Jain, R., Ray, D., Ried-Larsen, M., Saeed, Z., Santhakumar, V., Kanbour, S., Sarkar, S., Monaco, G. S. F., Scholtens, D. M., Selvin, E., Sheu, W. H. H., Speake, C., Stanislawski, M. A., Steenackers, N., Steck, A. K., Stefan, N., Støy, J., Taylor, R., Tye, S. C., Ukke, G. G., Urazbayeva, M., Van der Schueren, B., Vatier, C., Wentworth, J. M., Hannah, W., White, S. L., Yu, G., Zhang, Y., Zhou, S. J., Beltrand, J., Polak, M., Aukrust, I., de Franco, E., Flanagan, S. E., Maloney, K. A., McGovern, A., Molnes, J., Nakabuye, Mariam, Njølstad, P. R., Pomares-Millan, H., Provenzano, M., Saint-Martin, C., Zhang, C., Zhu, Y., Auh, S., de Souza, R., Fawcett, A. J., Gruber, C., Mekonnen, E. G., Mixter, E., Sherifali, D., Eckel, R. H., Nolan, J. J., Philipson, L. H., Brown, R. J., Billings, L. K., Boyle, K., Costacou, T., Dennis, J. M., Florez, J. C., Gloyn, A. L., Gomez, M. F., Gottlieb, P. A., Greeley, S. A. W., Griffin, K., Hattersley, A. T., Hirsch, I. B., Hivert, M. F., Hood, K. K., Josefson, J. L., Kwak, S. H., Laffel, L. M., Lim, S. S., Loos, Ruth, Ma, R. C. W., Mathieu, C., Mathioudakis, N., Meigs, J. B., Misra, S., Mohan, V., Murphy, R., Oram, R., Owen, K. R., Ozanne, S. E., Pearson, E. R., Perng, W., Pollin, T. I., Pop-Busui, R., Pratley, R. E., Redman, L. M., Redondo, M. J., Reynolds, R. M., Semple, R. K., Sherr, J. L., Sims, E. K., Sweeting, A., Tuomi, T., Udler, M. S., Vesco, K. K., Vilsbøll, Tina, Wagner, R., Rich, S. S. & Franks, P. W., 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Uncovering CNS access of lipidated exendin-4 analogues by quantitative whole-brain 3D light sheet imaging

    Skovbjerg, G., Roostalu, U., Salinas, C. G., Skytte, J. L., Perens, J., Clemmensen, Christoffer, Elster, L., Frich, C. K., Hansen, H. H. & Hecksher-Sørensen, J., 2023, In: Neuropharmacology. 238, 109637.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2022
  26. Published

    Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice

    Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

    Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice

    Breum, Alberte Wollesen, Falk, S., Svendsen, C. S. A., Nicolaisen, T. S., Mathiesen, C. V., Maskos, U. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 7, 9 p., bqac079.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 16824492