Catharina Margrethe Lerche

Catharina Margrethe Lerche

Associate Professor


Publication year:
  1. 2024
  2. Published

    Ablative fractional laser treatment reduces hedgehog pathway gene expression in murine basal cell carcinomas

    Pedersen, K. K., Granborg, J. R., Lerche, Catharina Margrethe, Litman, Thomas, Olesen, U. H. & Hædersdal, Merete, 2024, In: Lasers in Medical Science. 39, 1, 9 p., 55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Anti-PD-1 immunotherapy with adjuvant ablative fractional laser displays increased tumour clearance of squamous cell carcinoma, a murine study

    Christensen, R. L., Wiinberg, M., Lerche, Catharina Margrethe, Demehri, S., Olesen, U. H. & Hædersdal, Merete, 2024, In: Experimental Dermatology. 33, 2, 9 p., e15013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Oral administration of quercetin and fisetin potentiates photocarcinogenesis in UVR-exposed hairless mice

    Pihl, Celina, Granborg, J. R., Pinto, F. E., Bjerring, P., Andersen, F., Janfelt, Christian, Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Phytomedicine Plus. 4, 2, 8 p., 100547.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Oral intake of bucillamine, carvedilol, metformin, or phenformin does not protect against UVR-induced squamous cell carcinomas in hairless mice

    Pihl, Celina, Bjerring, P., Andersen, F., Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Photochemical and Photobiological Sciences. 23, p. 517-526

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Accepted/In press

    Urinary thymidine dimer excretion reflects personal ultraviolet radiation exposure levels

    Lerche, Catharina Margrethe, Frederiksen, N. J. S., Thorsteinsson, I. S., Køster, B., Nybo, Lars, Flouris, A. D., Heydenreich, J., Philipsen, P. A., Hædersdal, Merete, Wulf, H. C. & Granborg, J. R., 2024, (Accepted/In press) In: Photochemical and Photobiological Sciences.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2023
  8. Published

    A randomized, placebo-controlled, trial to assess the photosensitizing, phototoxic and carcinogenic potential of hydrochlorothiazide in healthy volunteers

    Götzinger, F., Hohl, M., Lauder, L., Millenaar, D., Kunz, M., Meyer, M. R., Ukena, C., Lerche, Catharina Margrethe, Philipsen, P. A., Reichrath, J., Böhm, M. & Mahfoud, F., 2023, In: Journal of Hypertension. 41, 11, p. 1853-1862

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis

    Meyer, Olivia Luxford, Andersen, M. M., Børsting, Claus, Morling, Niels, Wulf, H. C., Philipsen, P. A., Lerche, Catharina Margrethe & Andersen, Jeppe Dyrberg, 2023, In: Epigenetics. 18, 1, 10 p., 2144574 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Does systemic hydrochlorothiazide increase the risk of developing ultraviolet radiation-induced skin tumours in hairless mice?

    Lerche, Catharina Margrethe, Al-Chaer, R. N. & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 4, p. 341-347

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Experimental and approved treatments for skin photosensitivity in individuals with erythropoietic protoporphyria or X-linked protoporphyria: A systematic review

    Heerfordt, I. M., Lerche, Catharina Margrethe, Philipsen, P. A. & Wulf, H. C., 2023, In: Biomedicine and Pharmacotherapy. 158, 11 p., 114132.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Improving the efficacy of photodynamic therapy for actinic keratosis: A comprehensive review of pharmacological pretreatment strategies

    Pihl, Celina, Lerche, Catharina Margrethe, Andersen, F., Bjerring, P. & Hædersdal, Merete, 2023, In: Photodiagnosis and Photodynamic Therapy. 43, 8 p., 103703.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid

    Pihl, Celina, Bendtsen, K. M. S., Jensen, Henrik Elvang, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2023, In: Journal of Photochemistry and Photobiology B: Biology. 246, 112760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Phototesting in erythropoietic protoporphyria trials: A systematic review

    Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Experimental Dermatology. 32, 7, p. 1042-1047

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Protection against visible light by dihydroxyacetone in erythropoietic protoporphyria

    Heerfordt, I. M., Philipsen, P. A., Lerche, Catharina Margrethe & Wulf, H. C., 2023, In: Photodiagnosis and Photodynamic Therapy. 41, 5 p., 103302.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Repeated exposure to fractional CO2 laser delays squamous cell carcinoma formation and prevents clinical and subclinical photodamage visualized by line-field confocal optical coherence tomography and histology

    Olesen, U. H., Jacobsen, K., Lerche, Catharina Margrethe & Hædersdal, Merete, 2023, In: Lasers in Surgery and Medicine. 55, 1, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2022
  18. Published

    A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars: A blinded randomized controlled trial

    Erlendsson, A. M., Rosenberg, L. K., Lerche, Catharina Margrethe, Togsverd-Bo, K., Wiegell, Stine Regin, Karmisholt, Katrine Elisabeth, Philipsen, P. A., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Holmes, J., Rossi, A. & Hædersdal, Merete, 2022, In: Lasers in Surgery and Medicine. 54, 5, p. 663-671

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cimetidine for erythropoietic protoporphyria

    Heerfordt, I. M., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 38, 5 p., 102793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Detection of cutaneous malignant melanoma using RNA sampled by tape strips: A study protocol

    Heerfordt, I. M., Andersen, Jeppe Dyrberg, Philipsen, P. A., Langhans, L., Tvedebrink, Torben, Schmidt, G., Poulsen, T., Lerche, Catharina Margrethe, Morling, Niels & Wulf, H. C., 2022, In: PLoS ONE. 17, 9 , 11 p., e0274413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Distribution of protoporphyrin IX in erythrocytes in a case of acquired erythropoietic protoporphyria

    Heerfordt, I. M., Fontenete, S., Lerche, Catharina Margrethe & Wulf, H. C., 2022, In: Photodiagnosis and Photodynamic Therapy. 37, 3 p., 102629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    High Oral Vitamin D3 Intake Does Not Protect Against UVR-induced Squamous Cell Carcinoma in Mice

    Lerche, Catharina Margrethe, Pinto, F. E., Philipsen, P. A., Bech, E. S., Jakobsen, J., Hædersdal, Merete & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5083-5090

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    High oral vitamin D intake does not protect against UVR-induced squamous cell carcinoma in hairless mice

    Lerche, Catharina Margrethe, Pinto, F. E., Philipsen, P. A., Bech, E., Jakobsen, J., Hædersdal, Merete & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2205-2205

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    In vivo dermal delivery of bleomycin with electronic pneumatic injection: drug visualization and quantification with mass spectrometry

    Bik, L., van Doorn, M., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Olesen, U. H., Hædersdal, Merete, Lerche, Catharina Margrethe & Hendel, K., 2022, In: Expert Opinion on Drug Delivery. 19, 2, p. 213-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Nicotinamide and phytochemicals phloroglucinol and syringic acid delay uvr-induced squamous cell carcinoma onset in hairless mice

    Pihl, Celina, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2022, In: Anticancer Research. 42, 4, p. 2207-2207

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Quantification of Urinary Thymidine Dimers in Volunteers After Ultraviolet Radiation Using a New UPLC-MS/MS-based Method

    Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5069-5076

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Quantifying urinary thymine dimers based on LC-MS/MS

    Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2204-2204 22.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. Published

    Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration

    Traberg, A., Pinto, F. E., Hansen, Anders Christian Nørgaard, Hædersdal, Merete, Lerche, Catharina Margrethe & Janfelt, Christian, 2022, In: Pharmaceuticals. 15, 12, 15 p., 1583.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Topical Brimonidine Delays Ultraviolet Radiation-Induced Squamous Cell Carcinoma in Hairless Mice

    Pinto, F. E., Olsen, P., Glud, M., Wulf, H. C. & Lerche, Catharina Margrethe, 2022, In: Photochemistry and Photobiology. 98, 6, p. 1390-1394

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2021
  31. Published

    A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy

    Wulf, H. C., Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Lerche, Catharina Margrethe, May 2021, In: Pharmaceuticals. 14, 5, 11 p., 433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging

    Hendel, K., Hansen, Anders Christian Nørgaard, Bik, L., Bagger, C., van Doorn, M. B. A., Janfelt, Christian, Olesen, U. H., Hædersdal, Merete & Lerche, Catharina Margrethe, 1 Jan 2021, In: Drug Delivery. 28, 1, p. 1141-1149 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    A Comparison of Human and Porcine Skin in Laser-Assisted Drug Delivery of Chemotherapeutics

    Rosenberg, L. K., Bagger, C., Janfelt, Christian, Hædersdal, Merete, Olesen, U. H. & Lerche, Catharina Margrethe, 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 162-170 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Anti-pd-1 therapy with adjuvant ablative fractional laser improves anti-tumor response in basal cell carcinomas

    Olesen, U. H., Wiinberg, M., Lerche, Catharina Margrethe, Jæhger, D. E., Andresen, T. L. & Hædersdal, Merete, 2021, In: Cancers. 13, 24, 14 p., 6326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice

    Lerche, Catharina Margrethe, Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Wulf, H. C., 2021, In: Photochemical and Photobiological Sciences. 20, 10, p. 1299-1307

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Keratinocyte Carcinoma and Photoprevention: The Protective Actions of Repurposed Pharmaceuticals, Phytochemicals and Vitamins

    Pihl, Celina, Togsverd-Bo, K., Andersen, F., Hædersdal, Merete, Bjerring, P. & Lerche, Catharina Margrethe, 2021, In: Cancers. 13, 15, 29 p., 3684.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Tumor Clearance and Immune Cell Recruitment in UV-Induced Murine Squamous Cell Carcinoma Exposed to Ablative Fractional Laser and Imiquimod Treatment

    Fontenete, S., Lerche, Catharina Margrethe, Paasch, U., Perez-Moreno, Mirna, Olesen, U. H. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 9, p. 1227-1237 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2020
  39. Published

    Enhanced and Sustained Cutaneous Delivery of Vismodegib by Ablative Fractional Laser and Microemulsion Formulation

    Olesen, U. H., Clergeaud, G., Hendel, K. K., Yeung, Kelvin, Lerche, Catharina Margrethe, Andresen, T. L. & Hædersdal, Merete, 2020, In: Journal of Investigative Dermatology. 140, 10, p. 2051-2059 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 250642459