Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

Publication year:
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1 - 125 out of 125Page size: 500
  1. 2024
  2. Published

    BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis

    Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

    Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2023
  5. Published

    Overall Survival in Patients with Ccus Depends on Presence of Anemia

    Træden, D., Tulstrup, Morten Rytter, Johansen, Morten Munk, mxz703, mxz703, Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-Mønch, Kim, Jespersen, J., Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, Jakob Werner, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 1864-1864

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of IL9 during Allergic Lung Inflammation

    Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., Birdsey, G. M., Porse, Bo Torben, Randi, A. M. & Kaplan, M. H., 2023, In: Journal of Immunology. 210, 5, p. 537-546

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition

    Petrosius, V., Aragon-Fernandez, P., Üresin, Nil, Kovacs, G., Phlairaharn, T., Furtwängler, Benjamin, Op De Beeck, J., Skovbakke, S. L., Goletz, S., Thomsen, Simon Francis, Keller, U. A. D., Natarajan, K. N., Porse, Bo Torben & Schoof, E. M., 2023, In: Nature Communications. 14, 16 p., 5910.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis

    Nørgaard, Steffen, Tapia, Marta Cecylia, Zeijdner, Mandoh Johannes Seydin, Kim, J. H., Won, K. J., Porse, Bo Torben & Salcini, Anna Elisabetta, 2023, In: Life Science Alliance. 6, 8, 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

    Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

    Pundhir, Sachin, Su, Jinyu, Tapia, Marta Cecylia, Hansen, A. M., Haile, James Seymour, Hansen, K. & Porse, Bo Torben, 2023, In: Genome Research. 33, 3, p. 332-345 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2022
  14. Published

    Dynamic intron retention modulates gene expression in the monocytic differentiation pathway

    Song, R., Tikoo, S., Jain, R., Pinello, N., Au, A. Y. M., Nagarajah, R., Porse, Bo Torben, Rasko, J. E. J. & J.-L. Wong, J., 2022, In: Immunology. 165, 2, p. 274-286

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis

    Grigoryan, A., Zacharaki, D., Balhuizen, A., Côme, C. R., Garcia, A. G., Hidalgo Gil, D., Frank, A. K., Aaltonen, K., Mañas, A., Esfandyari, J., Kjellman, P., Englund, E., Rodriguez, C., Sime, W., Massoumi, R., Kalantari, N., Prithiviraj, S., Li, Y., Dupard, S. J., Isaksson, H. & 4 others, Madsen, C. D., Porse, Bo Torben, Bexell, D. & Bourgine, P. E., 2022, In: Science Translational Medicine. 14, 666, 16 p., eabm6391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target

    Vanner, R. J., Dobson, S. M., Gan, O. I., McLeod, J., Schoof, E. M., Grandal, I., Wintersinger, J. A., Garcia-Prat, L., Hosseini, M., Xie, S. Z., Jin, L., Mbong, N., Voisin, V., Chan-Seng-Yue, M., Kennedy, J. A., Waanders, E., Morris, Q., Porse, B., Chan, S. M., Guidos, C. J. & 4 others, Danska, J. S., Minden, M. D., Mullighan, C. G. & Dick, J. E., 2022, In: Blood cancer discovery. 3, 1, p. 16-31 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents

    Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Progression of the pluripotent epiblast depends upon the NMD factor UPF2

    Chousal, J. N., Sohni, A., Vitting-Seerup, K., Cho, K., Kim, M., Tan, K., Porse, Bo Torben, Wilkinson, M. F. & Cook-Andersen, H., 2022, In: Development. 149, 21, 15 p., dev200764.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

    Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, K., Huguet, R., Lopez-Ferrer, D., Zabrouskov, V., Porse, Bo Torben & Schoof, E. M., 2022, In: Molecular and Cellular Proteomics. 21, 4, 100219.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome

    Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  22. Published

    Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

    Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2021
  24. Published

    Quantitative single-cell proteomics as a tool to characterize cellular hierarchies

    Schoof, E. M., Furtwängler, Benjamin, Üresin, Nil, Rapin, N., Savickas, S., Gentil, C., Lechman, E., Keller, U. A. D., Dick, J. E. & Porse, Bo Torben, 7 Jun 2021, In: Nature Communications. 12, 1, p. 3341

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Basement membrane stiffness determines metastases formation

    Reuten, R., Zendehroud, S., Nicolau, M., Fleischhauer, L., Laitala, A., Kiderlen, S., Nikodemus, D., Wullkopf, L., Nielsen, S. R., Mcneilly, S., Prein, C., Rafaeva, M., Schoof, E. M., Furtwängler, B., Porse, B. T., Kim, H., Won, K. J., Sudhop, S., Zornhagen, K. W., Suhr, F. & 11 others, Maniati, E., Pearce, O. M. T., Koch, M., Oddershede, L. B., Van Agtmael, T., Madsen, C. D., Mayorca Guiliani, Alejandro Enrique, Bloch, W., Netz, R. R., Clausen-schaumann, H. & Erler, Janine, 2021, In: Nature Materials. 20, p. 892–903

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy

    Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia

    D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The eha research roadmap: normal hematopoiesis

    Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, Kleanthous, M., Klump, H., Kouskoff, V., Krause, D., Lacaud, G., Lo Celso, C., Martens, J. H. A., Méndez-Ferrer, S., Menendez, P., Oostendorp, R., Philipsen, S., Porse, Bo Torben, Raaijmakers, M., Robin, C., Stunnenberg, H., Theilgaard-Mønch, Kim, Touw, I., Vainchenker, W., Corrons, J. L. V., Yvernogeau, L. & Schuringa, J. J., 2021, In: HemaSphere. 5, 12, e669.

    Research output: Contribution to journal › Review › Research › peer-review

  29. 2020
  30. Published

    CCAAT enhancer binding protein alpha (CEBPA) biallelic acute myeloid leukaemia: cooperating lesions, molecular mechanisms and clinical relevance

    Wilhelmson, Anna & Porse, Bo Torben, 2020, In: British Journal of Haematology. 190, 4, p. 495-507

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Myelodysplastic syndrome patient-derived xenografts: from no options to many

    Côme, Christophe Roger Michel, Balhuizen, Alexander, Bonnet, D. & Porse, Bo Torben, 2020, In: Haematologica. 105, 4, p. 864-869

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2019
  33. Published

    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination

    Søndergaard, E., Rauch, A., Michaut, Magali, Rapin, N., Rehn, M., Wilhelmson, Anna, Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L. & Porse, Bo Torben, 26 Nov 2019, In: Cell Reports. 29, 9, p. 2756-2769.e6 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

    Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, Bo Torben, Enright, A. J. & O'Carroll, D., 2019, In: Cell Research. p. 221–232

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes

    D'Altri, T., Schuster, Mikkel Bruhn, Wenzel, Anne & Porse, Bo Torben, 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    Johnson, J. L., Stoica, L., Liu, Y., Zhu, P. J., Bhattacharya, A., Buffington, S., Huq, R., Eissa, N. T., Larsson, O., Porse, B. T., Domingo, D., Nawaz, U., Carroll, R., Jolly, L., Scerri, T. S., Kim, H-G., Brignell, A., Coleman, M. J., Braden, R., Kini, U. & 11 others, Jackson, V., Baxter, A., Bahlo, M., Scheffer, I. E., Amor, D. J., Hildebrand, M. S., Bonnen, P. E., Beeton, C., Gecz, J., Morgan, A. T. & Costa-Mattioli, M., 2019, In: Neuron. 104, 4, p. 665-679 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

    Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2018
  40. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, Anna, Pundhir, Sachin, Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, Palle, Amit, I. & Porse, Bo Torben, 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

    Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates

    Gu, X., Ebrahem, Q., Mahfouz, R. Z., Hasipek, M., Enane, F., Radivoyevitch, T., Rapin, N., Przychodzen, B., Hu, Z., Balusu, R., Cotta, C. V., Wald, D., Argueta, C., Landesman, Y., Martelli, M. P., Falini, B., Carraway, H., Porse, B. T., Maciejewski, J., Jha, B. K. & 1 others, Saunthararajah, Y., 2018, In: The Journal of Clinical Investigation. 128, 10, p. 4260-4279 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    SinaPlot: an enhanced chart for simple and truthful representation of single observations over multiple classes

    Sidiropoulos, N., Sohi, S. H., Pedersen, T. L., Porse, Bo Torben, Winther, Ole, Rapin, N. & Bagger, F. O., 2018, In: Journal of Computational and Graphical Statistics. 27, 3, p. 673-676 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Testosterone is an endogenous regulator of BAFF and splenic B cell number

    Wilhelmson, A. S., Lantero Rodriguez, M., Stubelius, A., Fogelstrand, P., Johansson, I., Buechler, M. B., Lianoglou, S., Kapoor, V. N., Johansson, M. E., Fagman, J. B., Duhlin, A., Tripathi, P., Camponeschi, A., Porse, B. T., Rolink, A. G., Nissbrandt, H., Turley, S. J., Carlsten, H., Mårtensson, I-L., Karlsson, M. C. I. & 1 others, Tivesten, Å., 2018, In: Nature Communications. 9, p. 1-13 13 p., 2067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2017
  48. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2016

  50. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Stunnenberg, H. G., Hirst, M., International Human Epigenome Consortium, I. H. E. C., Helin, K. & Porse, Bo Torben, 17 Nov 2016, In: Cell. 167, 5, p. 1145-1149 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia

    O'Connor, C., Lohan, F., Campos, J., Ohlsson, E., Salomè, M., Forde, C., Artschwager, R., Liskamp, R. M., Cahill, M. R., Kiely, P. A., Porse, Bo Torben & Keeshan, K., 6 Oct 2016, In: Oncogene. 35, 40, p. 5272-5281 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4

    Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

    Ohlsson, E., Schuster, Mikkel Bruhn, Hasemann, M. & Porse, Bo Torben, Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

    Bagger, F. O., Sasivarevic, D., Hadi Sohi, S., Laursen, L. G., Pundhir, Sachin, Sønderby, C. K., Winther, Ole, Rapin, N. & Porse, Bo Torben, 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D917-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

    Pundhir, Sachin, Bagger, F. O., Lauridsen, F. K. B., Rapin, N. P. J. & Porse, Bo Torben, 2016, In: Nucleic Acids Research. 44, 9, p. 4037-4051 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts

    Bao, J., Vitting-Seerup, K., Waage, J. E., Tang, C., Ge, Y., Porse, Bo Torben & Yan, W., 2016, In: P L o S Genetics. 12, 5, 24 p., e1005863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2015
  58. Published

    Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F. K. B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B. T. & 2 others, Tanay, A. & Amit, I., 17 Dec 2015, In: Cell. 163, 7, p. 1663-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Disease evolution and outcomes in familial AML with germline CEBPA mutations

    Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F. W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K. & 21 others, Bullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, Anne-Katrine, Lauridsen, F. B., Porse, Bo Torben, Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. & Fitzgibbon, J., 3 Sep 2015, In: Blood. 126, 10, p. 1214-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

    Rasmussen, K. D., Jia, G., Johansen, Jens Vilstrup, Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, Bo Torben, Bernard, O. A., Christensen, J. & Helin, K., 17 Apr 2015, In: Genes & Development. p. 910-922 13 p., 29.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Cellular origin of prognostic chromosomal aberrations in AML patients

    Mora-Jensen, H., Jendholm, L. J., Rapin, N. P. J., Andersen, M. K., Roug, A. S., Bagger, F. O., Bullinger, L., Winther, Ole, Borregaard, N., Porse, Bo Torben & Theilgaard-Mønch, Kim, 11 Feb 2015, In: Leukemia. 29, p. 1785-1789 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: A critical role for IL-6/STAT3

    Xu, M., Feng, D., Wu, H., Wang, H., Chan, Y., Kolls, J., Borregaard, N., Porse, Bo Torben, Berger, T., Mak, T. W., Cowland, J. B., Kong, X. & Gao, B., Feb 2015, In: Hepatology. 61, 2, p. 692-702 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

    Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Waage, J., Vitting-Seerup, K. & Porse, Bo Torben, 2015, In: BMC Genomics. 16, p. 46

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

    Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, Anne-Katrine, Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, Kim & Porse, Bo Torben, 2015, In: Genes & Development. 29, p. 1915-1929 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia

    Willer, A., Jakobsen, J. S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. & Porse, Bo Torben, 2015, In: Leukemia. 29, p. 1018-31 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome

    Bao, J., Tang, C., Yuan, S., Porse, Bo Torben & Yan, W., 2015, In: Development (Cambridge, England). 142, p. 352-362 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. 2014
  68. Published

    Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation

    Rishi, L., Hannon, M., Salomè, M., Hasemann, M., Frank, Anne-Katrine, Campos, J., Timoney, J., O'Connor, C., Cahill, M. R., Porse, Bo Torben & Keeshan, K., 10 Apr 2014, In: Blood. 123, 15, p. 2389-400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients

    Rapin, N. P. J., Bagger, F. O., Jendholm, L. J., Mora-Jensen, H., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 6 Feb 2014, In: Blood (online). 123, 6, p. 894-904 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    shRNA screening identifies JMJD1C as being required for leukemia maintenance

    Sroczynska, P., Cruickshank, V. A., Bukowski, J., Miyagi, S., Bagger, F. O., Walfridsson, J., Schuster, Mikkel Bruhn, Porse, Bo Torben & Helin, K., 5 Feb 2014, In: Blood (online).

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Integrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models

    Klein, H., Schäfer, M., Porse, Bo Torben, Hasemann, M. S., Ickstadt, K. & Dugas, M., 22 Jan 2014, In: Bioinformatics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Initiation of MLL-rearranged AML is dependent on C/EBPα

    Ohlsson, E., Hasemann, M. S., Willer, A., Lauridsen, F. K. B., Rapin, N. P. J., Jendholm, L. J. & Porse, Bo Torben, 13 Jan 2014, In: The Journal of Experimental Medicine. 211, 1, p. 5-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

    Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Rapin, N. P. J., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, Bo Torben, Jan 2014, In: P L o S Genetics (Online). 10, 1, p. 1-10 10 p., e1004079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner

    Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML

    Rapin, N. & Porse, Bo Torben, 2014, In: Oncogenesis. 3, p. 1-5 5 p., e106.

    Research output: Contribution to journal › Letter › Research › peer-review

  76. Published

    spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data

    Vitting-Seerup, K., Porse, Bo Torben, Sandelin, Albin Gustav & Waage, J., 2014, In: B M C Bioinformatics. 15, p. 1-7 7 p., 81.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. 2013
  78. Published

    The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression

    Ge, Y. & Porse, Bo Torben, 18 Dec 2013, In: BioEssays.

    Research output: Contribution to journal › Review › Research › peer-review

  79. Published

    Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors

    Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Bagger, F. O., Rapin, N., Vikesaa, J. & Porse, Bo Torben, Oct 2013, In: Experimental Hematology. 41, 10, p. 882-893 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus

    Leucci, E., Patella, F., Waage, J., Holmstrøm, K., Lindow, M., Porse, Bo Torben, Kauppinen, S. & Lund, Anders H., 29 Aug 2013, In: Scientific Reports. 3, p. 2535

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells

    Thoren, L. A., Fog, C. K., Jensen, K. T., Buza-Vidas, N., Côme, Christophe Roger Michel, Lund, Anders H. & Porse, Bo Torben, 9 Aug 2013, In: Stem Cell Research. 11, 3, p. 1129-1136 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

    Jakobsen, J. S., Waage, J., Rapin, N., Bisgaard, Hanne Cathrine, Larsen, F. S. & Porse, Bo Torben, Apr 2013, In: Genome Research. 23, 4, p. 592-603 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis

    Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Improving The Analysis Of Gene Expression Profiles By Comparing AML Blasts With Their Nearest Normal Counterparts

    Rapin, N., Bagger, F. O., Jendholm, J., Mora-Jensen, H. I., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 2013, In: Blood. 122, 21

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  85. Published

    Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay

    Colak, D., Ji, S., Porse, Bo Torben & Jaffrey, S. R., 2013, In: Cell. 153, 6, p. 1252-65 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. 2012
  87. Published

    PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

    Zheng, S., Gray, E. E., Chawla, G., Porse, Bo Torben, O'Dell, T. J. & Black, D. L., Mar 2012, In: Nature Neuroscience. 15, 3, p. 381-8, S1

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

    Treppendahl, M. B., Qiu, X., Søgaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Möllgård, L., Möllgaard, L., Hellström-Lindberg, E., Jendholm, L. J., Porse, Bo Torben, Jones, P. A., Liang, G. & Grønbæk, Kirsten, 5 Jan 2012, In: Blood. 119, 1, p. 206-16 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    BLUEPRINT to decode the epigenetic signature written in blood

    Adams, D., Altucci, L., Antonarakis, S. E., Ballesteros, J., Beck, S., Bird, A., Bock, C., Boehm, B., Campo, E., Caricasole, A., Dahl, F., Dermitzakis, E. T., Enver, T., Esteller, M., Estivill, X., Ferguson-Smith, A., Fitzgibbon, J., Flicek, P., Giehl, C., Graf, T. & 37 others, Grosveld, F., Guigo, R., Gut, I., Helin, K., Jarvius, J., Küppers, R., Lehrach, H., Lengauer, T., Lernmark, Å., Leslie, D., Loeffler, M., Macintyre, E., Mai, A., Martens, J. H. A., Minucci, S., Ouwehand, W. H., Pelicci, P. G., Pendeville, H., Porse, Bo Torben, Rakyan, V., Reik, W., Schrappe, M., Schübeler, D., Seifert, M., Siebert, R., Simmons, D., Soranzo, N., Spicuglia, S., Stratton, M., Stunnenberg, H. G., Tanay, A., Torrents, D., Valencia, A., Vellenga, E., Vingron, M., Walter, J. & Willcocks, S., 2012, In: Nature Biotechnology. 30, 3, p. 224-6 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  90. Published

    HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis

    Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Jendholm, L. J., Winther, O. & Porse, Bo Torben, 2012, In: Blood. 119, 26, p. 6394-6395 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  91. Published

    Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

    Weischenfeldt, Joachim Lütken, Waage, J. E., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, Karsten, Krogh, Anders, Wang, J. & Porse, Bo Torben, 2012, In: Genome Biology (Online Edition). 13, 5, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

    Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Theilgaard-Mønch, Kim, Pedersen, T. Å., Nerlov, C. & Porse, Bo Torben, 2012, In: P L o S One. 7, 6, p. e38841

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. 2011
  94. Published

    Immunophenotypical characterization of human neutrophil differentiation

    Jensen, H. M., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaad, N. & Theilgaard-Mønch, Kim, 7 Jun 2011, In: Journal of Leukocyte Biology. p. 629-634 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Gene expression profiling in MDS and AML: potential and future avenues

    Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A., Morgan, M., Porse, B., Tagliafico, E., Zwaan, C. M., Wainscoat, J., Van den Heuvel-Eibrink, M. M., Mills, K., Bullinger, L., Theilgaard-Mönch, K., Boultwood, J., Ferrari, S., Giannopoulos, K., Hernandez-Rivas, J. M., Kohlmann, A. & 8 others, Morgan, M., Porse, Bo Torben, Tagliafico, E., Zwaan, C. M., Wainscoat, J., Van den Heuvel-Eibrink, M. M., Mills, K. & Bullinger, L., 2011, In: Leukemia. 25, 6, p. 909-20 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Technical advance: immunophenotypical characterization of human neutrophil differentiation

    Mora-Jensen, H. I., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaard, N. & Theilgaard-Mönch, K., 2011, In: Journal of Leukocyte Biology. 90, 3, p. 629-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. 2010
  98. Published

    Basal stamcellebiologi og cancer

    Porse, Bo Torben, Petersen, Ole William & Helin, K., 20 Sep 2010, In: Ugeskrift for læger. 172, 38, p. 2600-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

    Pasini, D., Malatesta, M., Jung, H. R., Valfridsson, J. O. A., Willer, A., Olsson, L., Skotte, J., Wutz, A., Porse, Bo Torben, Jensen, O. N. & Helin, K., Aug 2010, In: Nucleic Acids Research. 38, 15, p. 4958-69 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Lipocalin 2 is protective against E. coli pneumonia

    Wu, H., Santoni Rugiu, Eric, Ralfkiaer, E., Porse, Bo Torben, Moser, C., Høiby, Niels, Borregaard, N., Cowland, J. B., Wu, H., Santoni Rugiu, Eric, Ralfkiær, E., Porse, B. T., Moser, C. E., Høiby, N., Borregaard, N. & Cowland, J., 15 Jun 2010, In: Respiratory research (Online). 11, 96, 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Lipocalin 2 is protective against E. coli pneumonia

    Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, Bo Torben, Moser, Claus Ernst, Høiby, Niels, Borregaard, N. & Cowland, J. B., 2010, In: Respiratory research. 11, p. 96

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    UPF2 is a critical regulator of liver development, function and regeneration

    Thoren, L. A., Nørgaard, G. A., Weischenfeldt, Joachim Lütken, Waage, J., Jakobsen, J. S., Damgaard, I., Bergström, F. C., Blom, A. M., Borup, R., Bisgaard, Hanne Cathrine & Porse, Bo Torben, 2010, In: PLoS ONE. 5, 7, p. e11650

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. 2009
  105. Published

    C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2009, In: BioFactors. 35, 3, p. 227-31 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Leukemia - methods and protocols

    Porse, Bo Torben, 2009, In: European Journal of Haematology. 84, 1, p. 94

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. 2008
  108. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.

    Research output: Contribution to journal › Journal article › Research

  109. Published

    Bone Marrow-derived Macrophages (BMMs): Isolation and applications.

    Weischenfeldt, Joachim Lütken & Porse, Bo Torben, 2008, In: Cold Spring Harbor Protocols.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, C., Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlback, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 4, p. 1839-1847 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  111. Published

    Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.

    Kirstetter, P., Schuster, Mikkel Bruhn, Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mønch, Kim, Månsson, R., Pedersen, T. A., Pabst, T., Schrock, E., Porse, Bo Torben, Jacobsen, S. E. W., Bertone, P., Tenen, D. G. & Nerlov, C., 2008, In: Cancer Cell. 13, 4, p. 299-310 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.

    Hasemann, M. S., Damgaard, I., Schuster, Mikkel Bruhn, Theilgaard-Mønch, Kim, Sørensen, A. B., Mrsic, A., Krugers, T., Ylstra, B., Pedersen, F. S., Nerlov, C. & Porse, Bo Torben, 2008, In: Blood. 111, 8, p. 4309-21 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. Published

    NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements.

    Weischenfeldt, Joachim Lütken, Damgaard, I., Bryder, D., Theilgaard-Mønch, Kim, Thoren, L. A., Nielsen, F. C., Jacobsen, S. E. W., Nerlov, C. & Porse, Bo Torben, 2008, In: Genes & Development. 22, 10, p. 1381-96 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  114. 2007
  115. Published

    Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.

    Pedersen, T. A., Bereshchenko, O., Garcia-Silva, S., Ermakova, O., Kurz, E., Mandrup, S., Porse, Bo Torben & Nerlov, C., 2007, In: EMBO Journal. 26, 4, p. 1081-93 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  116. Published

    The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.

    Bracken, A. P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Mønch, Kim, Minucci, S., Porse, Bo Torben, Marine, J., Hansen, K. H. & Helin, K., 2007, In: Genes & Development. 21, 5, p. 525-30 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  117. 2006
  118. Published

    Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

    Kirstetter, P., Anderson, K., Porse, Bo Torben, Jacobsen, S. E. W. & Nerlov, C., 2006, In: Nature Immunology. 7, 10, p. 1048-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    C/EBPalpha: a tumour suppressor in multiple tissues?

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2006, In: BBA General Subjects. 1766, 1, p. 88-103 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  120. Published

    Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation.

    Theilgaard-Mønch, Kim, Jacobsen, L. C., Nielsen, M. J., Rasmussen, T., Udby, L., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Moestrup, S. K., Porse, Bo Torben & Borregaard, N., 2006, In: Blood. 108, 1, p. 353-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  121. Published

    The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo.

    Porse, Bo Torben, Pedersen, T. A., Hasemann, M. S., Schuster, Mikkel Bruhn, Kirstetter, P., Luedde, T., Damgaard, I., Kurz, E., Schjerling, C. K. & Nerlov, C., 2006, In: Molecular and Cellular Biology. 26, 3, p. 1028-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  122. 2005
  123. Published

    Highly glycosylated alpha1-acid glycoprotein is synthesized in myelocytes, stored in secondary granules, and released by activated neutrophils.

    Theilgaard-Mønch, Kim, Jacobsen, L. C., Rasmussen, T., Niemann, C. U., Udby, L., Borup, R., Gharib, M., Arkwright, P. D., Gombart, A. F., Calafat, J., Porse, Bo Torben & Borregaard, N., 2005, In: Journal of Leukocyte Biology. 78, 2, p. 462-70 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  124. Published

    Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage.

    Porse, Bo Torben, Bryder, D., Theilgaard-Mønch, Kim, Hasemann, M. S., Anderson, K., Damgaard, I., Jacobsen, S. E. W. & Nerlov, C., 2005, In: Journal of Experimental Medicine. 202, 1, p. 85-96 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  125. Published

    Messenger RNA surveillance: neutralizing natural nonsense.

    Weischenfeldt, Joachim Lütken, Lykke-Andersen, J. & Porse, Bo Torben, 2005, In: Current Biology. 15, 14, p. R559-62

    Research output: Contribution to journal › Journal article › Research › peer-review

  126. Published

    Systems biology of neutrophil differentiation and immune response.

    Theilgaard-Mønch, Kim, Porse, Bo Torben & Borregaard, N., 2005, In: Current Opinion in Immunology. 18, 1, p. 54-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  127. 2004
  128. Published

    A novel partial modification at C2501 in Escherichia coli 23S ribosomal RNA

    Andersen, T., Porse, Bo Torben & Kirpekar, F., 1 Jun 2004, In: RNA. 10, 6, p. 907-913 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  129. 2003
  130. Published

    A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel.

    Long, K. S. & Porse, Bo Torben, 2003, In: Nucleic Acids Research. 31, 24, p. 7208-15 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  131. Published

    Transgene mus som sygdomsmodeller.

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2003, In: Ugeskrift for læger. 165, 8, p. 793-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  132. 2001
  133. Published

    E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

    Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  134. 2000
  135. Published

    Puromycin-rRNA interaction sites at the peptidyl transferase center

    Rodriguez-Fonseca, C., Phan, H., Long, K. S., Porse, Bo Torben, Kirilov, S. V., Amils, R. & Garrett, Roger Antony, 2000, In: RNA: A publication of the RNA Society. 6, 5, p. 744-754 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  136. 1999
  137. Published

    Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.

    Porse, Bo Torben, Kirillov, S. V., Awayez, M. J., Ottenheijm, H. C. & Garrett, R. A., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, 16, p. 9003-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  138. Published

    Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome

    Kirillov, S. V., Porse, Bo Torben & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 8, p. 1003-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  139. Published

    Ribosomal mechanics, antibiotics, and GTP hydrolysis.

    Porse, Bo Torben & Garrett, R. A., 1999, In: Cell. 97, 4, p. 423-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  140. Published

    Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their binding mechanisms

    Porse, Bo Torben & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 286, p. 375-387

    Research output: Contribution to journal › Journal article › Research › peer-review

  141. Published

    Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms.

    Porse, Bo Torben & Garrett, R. A., 1999, In: Journal of Molecular Biology. 286, 2, p. 375-87 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  142. Published

    The antibiotic micrococcin acts on protein L11 at the ribosomal GTPase centre.

    Porse, Bo Torben, Cundliffe, E. & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 287, 1, p. 33-45 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  143. Published

    UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA.

    Porse, Bo Torben, Kirillov, S. V., Awayez, M. J. & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 4, p. 585-95 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  144. 1998
  145. Published

    Assembly of proteins and 5S rRNA to transcripts of the major structural domains of 23S rRNA

    Østergaard, P., Phan, H., Johansen, L. B., Egebjerg, J., Østergaard, L., Porse, Bo Torben & Garrett, Roger Antony, 1 Nov 1998, In: Journal of Molecular Biology. 284, 2, p. 227-240 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  146. Published

    The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre

    Porse, Bo Torben, Leviev, I., Mankin, A. S. & Garrett, R. A., 1998, In: Journal of Molecular Biology. 276, 2, p. 391-404 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  147. 1997
  148. Published

    Movement of the 3'-end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics

    Kirillov, S., Porse, Bo Torben, Vester, B., Woolley, P. & Garrett, Roger Antony, 1997, In: FEBS Letters. 406, 3, p. 223-233 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  149. 1996
  150. Published

    A sparsomycin-resistant mutant of Halobacterium salinarium lacks a modification at nucleotide U2603 in the peptidyl transferase centre of 23 S rRNA

    Lázaro, E., Rodriguez-Fonseca, C., Porse, Bo Torben, Ureña, D., Garrett, Roger Antony & Ballesta, J. P. G., 16 Aug 1996, In: Journal of Molecular Biology. 261, 2, p. 231-238 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  151. Published

    Antibiotic inhibition of the movement of tRNA substrates through a peptidyl transferase cavity.

    Porse, Bo Torben, Rodriguez-Fonseca, C., Leviev, I. & Garrett, R. A., 1996, In: Biochemistry and Cell Biology. 73, 11-12, p. 877-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  152. Published

    The donor substrate site within the peptidyl transferase loop of 23 S rRNA and its putative interactions with the CCA-end of N-blocked aminoacyl-tRNA(Phe).

    Porse, Bo Torben, Thi-Ngoc, H. P. & Garrett, R. A., 1996, In: Journal of Molecular Biology. 264, 3, p. 472-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  153. 1995
  154. Published

    Mapping important nucleotides in the peptidyl transferase centre of 23 S rRNA using a random mutagenesis approach.

    Porse, Bo Torben & Garrett, R. A., 1995, In: Journal of Molecular Biology. 249, 1, p. 1-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 4985646