Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2024
  2. Published

    BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis

    Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells

    Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Published

    Overall Survival in Patients with Ccus Depends on Presence of Anemia

    Træden, D., Tulstrup, Morten Rytter, Johansen, Morten Munk, mxz703, mxz703, Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-Mønch, Kim, Jespersen, J., Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, Jakob Werner, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 1864-1864

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    ERG Functionally Overlaps with Other Ets Proteins in Promoting TH9 Cell Expression of IL9 during Allergic Lung Inflammation

    Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., Birdsey, G. M., Porse, Bo Torben, Randi, A. M. & Kaplan, M. H., 2023, In: Journal of Immunology. 210, 5, p. 537-546

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Exploration of cell state heterogeneity using single-cell proteomics through sensitivity-tailored data-independent acquisition

    Petrosius, V., Aragon-Fernandez, P., Üresin, Nil, Kovacs, G., Phlairaharn, T., Furtwängler, Benjamin, Op De Beeck, J., Skovbakke, S. L., Goletz, S., Thomsen, Simon Francis, Keller, U. A. D., Natarajan, K. N., Porse, Bo Torben & Schoof, E. M., 2023, In: Nature Communications. 14, 16 p., 5910.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Inter and transgenerational impact of H3K4 methylation in neuronal homeostasis

    Nørgaard, Steffen, Tapia, Marta Cecylia, Zeijdner, Mandoh Johannes Seydin, Kim, J. H., Won, K. J., Porse, Bo Torben & Salcini, Anna Elisabetta, 2023, In: Life Science Alliance. 6, 8, 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

    Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

    Pundhir, Sachin, Su, Jinyu, Tapia, Marta Cecylia, Hansen, A. M., Haile, James Seymour, Hansen, K. & Porse, Bo Torben, 2023, In: Genome Research. 33, 3, p. 332-345 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2022
  14. Published

    Dynamic intron retention modulates gene expression in the monocytic differentiation pathway

    Song, R., Tikoo, S., Jain, R., Pinello, N., Au, A. Y. M., Nagarajah, R., Porse, Bo Torben, Rasko, J. E. J. & J.-L. Wong, J., 2022, In: Immunology. 165, 2, p. 274-286

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis

    Grigoryan, A., Zacharaki, D., Balhuizen, A., Côme, C. R., Garcia, A. G., Hidalgo Gil, D., Frank, A. K., Aaltonen, K., Mañas, A., Esfandyari, J., Kjellman, P., Englund, E., Rodriguez, C., Sime, W., Massoumi, R., Kalantari, N., Prithiviraj, S., Li, Y., Dupard, S. J., Isaksson, H. & 4 others, Madsen, C. D., Porse, Bo Torben, Bexell, D. & Bourgine, P. E., 2022, In: Science Translational Medicine. 14, 666, 16 p., eabm6391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target

    Vanner, R. J., Dobson, S. M., Gan, O. I., McLeod, J., Schoof, E. M., Grandal, I., Wintersinger, J. A., Garcia-Prat, L., Hosseini, M., Xie, S. Z., Jin, L., Mbong, N., Voisin, V., Chan-Seng-Yue, M., Kennedy, J. A., Waanders, E., Morris, Q., Porse, B., Chan, S. M., Guidos, C. J. & 4 others, Danska, J. S., Minden, M. D., Mullighan, C. G. & Dick, J. E., 2022, In: Blood cancer discovery. 3, 1, p. 16-31 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents

    Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Progression of the pluripotent epiblast depends upon the NMD factor UPF2

    Chousal, J. N., Sohni, A., Vitting-Seerup, K., Cho, K., Kim, M., Tan, K., Porse, Bo Torben, Wilkinson, M. F. & Cook-Andersen, H., 2022, In: Development. 149, 21, 15 p., dev200764.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics

    Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, K., Huguet, R., Lopez-Ferrer, D., Zabrouskov, V., Porse, Bo Torben & Schoof, E. M., 2022, In: Molecular and Cellular Proteomics. 21, 4, 100219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome

    Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  22. Published

    Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

    Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2021
  24. Published

    Quantitative single-cell proteomics as a tool to characterize cellular hierarchies

    Schoof, E. M., Furtwängler, Benjamin, Üresin, Nil, Rapin, N., Savickas, S., Gentil, C., Lechman, E., Keller, U. A. D., Dick, J. E. & Porse, Bo Torben, 7 Jun 2021, In: Nature Communications. 12, 1, p. 3341

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Basement membrane stiffness determines metastases formation

    Reuten, R., Zendehroud, S., Nicolau, M., Fleischhauer, L., Laitala, A., Kiderlen, S., Nikodemus, D., Wullkopf, L., Nielsen, S. R., Mcneilly, S., Prein, C., Rafaeva, M., Schoof, E. M., Furtwängler, B., Porse, B. T., Kim, H., Won, K. J., Sudhop, S., Zornhagen, K. W., Suhr, F. & 11 others, Maniati, E., Pearce, O. M. T., Koch, M., Oddershede, L. B., Van Agtmael, T., Madsen, C. D., Mayorca Guiliani, Alejandro Enrique, Bloch, W., Netz, R. R., Clausen-schaumann, H. & Erler, Janine, 2021, In: Nature Materials. 20, p. 892–903

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy

    Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia

    D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The eha research roadmap: normal hematopoiesis

    Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, Kleanthous, M., Klump, H., Kouskoff, V., Krause, D., Lacaud, G., Lo Celso, C., Martens, J. H. A., Méndez-Ferrer, S., Menendez, P., Oostendorp, R., Philipsen, S., Porse, Bo Torben, Raaijmakers, M., Robin, C., Stunnenberg, H., Theilgaard-Mønch, Kim, Touw, I., Vainchenker, W., Corrons, J. L. V., Yvernogeau, L. & Schuringa, J. J., 2021, In: HemaSphere. 5, 12, e669.

    Research output: Contribution to journalReviewResearchpeer-review

  29. 2020
  30. Published

    CCAAT enhancer binding protein alpha (CEBPA) biallelic acute myeloid leukaemia: cooperating lesions, molecular mechanisms and clinical relevance

    Wilhelmson, Anna & Porse, Bo Torben, 2020, In: British Journal of Haematology. 190, 4, p. 495-507

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Myelodysplastic syndrome patient-derived xenografts: from no options to many

    Côme, Christophe Roger Michel, Balhuizen, Alexander, Bonnet, D. & Porse, Bo Torben, 2020, In: Haematologica. 105, 4, p. 864-869

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2019
  33. Published

    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination

    Søndergaard, E., Rauch, A., Michaut, Magali, Rapin, N., Rehn, M., Wilhelmson, Anna, Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L. & Porse, Bo Torben, 26 Nov 2019, In: Cell Reports. 29, 9, p. 2756-2769.e6 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

    Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, Bo Torben, Enright, A. J. & O'Carroll, D., 2019, In: Cell Research. p. 221–232

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes

    D'Altri, T., Schuster, Mikkel Bruhn, Wenzel, Anne & Porse, Bo Torben, 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Inhibition of Upf2-Dependent Nonsense-Mediated Decay Leads to Behavioral and Neurophysiological Abnormalities by Activating the Immune Response

    Johnson, J. L., Stoica, L., Liu, Y., Zhu, P. J., Bhattacharya, A., Buffington, S., Huq, R., Eissa, N. T., Larsson, O., Porse, B. T., Domingo, D., Nawaz, U., Carroll, R., Jolly, L., Scerri, T. S., Kim, H-G., Brignell, A., Coleman, M. J., Braden, R., Kini, U. & 11 others, Jackson, V., Baxter, A., Bahlo, M., Scheffer, I. E., Amor, D. J., Hildebrand, M. S., Bonnen, P. E., Beeton, C., Gecz, J., Morgan, A. T. & Costa-Mattioli, M., 2019, In: Neuron. 104, 4, p. 665-679 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

    Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2018
  40. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, Anna, Pundhir, Sachin, Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, Palle, Amit, I. & Porse, Bo Torben, 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

    Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates

    Gu, X., Ebrahem, Q., Mahfouz, R. Z., Hasipek, M., Enane, F., Radivoyevitch, T., Rapin, N., Przychodzen, B., Hu, Z., Balusu, R., Cotta, C. V., Wald, D., Argueta, C., Landesman, Y., Martelli, M. P., Falini, B., Carraway, H., Porse, B. T., Maciejewski, J., Jha, B. K. & 1 others, Saunthararajah, Y., 2018, In: The Journal of Clinical Investigation. 128, 10, p. 4260-4279 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    SinaPlot: an enhanced chart for simple and truthful representation of single observations over multiple classes

    Sidiropoulos, N., Sohi, S. H., Pedersen, T. L., Porse, Bo Torben, Winther, Ole, Rapin, N. & Bagger, F. O., 2018, In: Journal of Computational and Graphical Statistics. 27, 3, p. 673-676 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Testosterone is an endogenous regulator of BAFF and splenic B cell number

    Wilhelmson, A. S., Lantero Rodriguez, M., Stubelius, A., Fogelstrand, P., Johansson, I., Buechler, M. B., Lianoglou, S., Kapoor, V. N., Johansson, M. E., Fagman, J. B., Duhlin, A., Tripathi, P., Camponeschi, A., Porse, B. T., Rolink, A. G., Nissbrandt, H., Turley, S. J., Carlsten, H., Mårtensson, I-L., Karlsson, M. C. I. & 1 others, Tivesten, Å., 2018, In: Nature Communications. 9, p. 1-13 13 p., 2067.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2017
  48. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2016
  50. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Stunnenberg, H. G., Hirst, M., International Human Epigenome Consortium, I. H. E. C., Helin, K. & Porse, Bo Torben, 17 Nov 2016, In: Cell. 167, 5, p. 1145-1149 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia

    O'Connor, C., Lohan, F., Campos, J., Ohlsson, E., Salomè, M., Forde, C., Artschwager, R., Liskamp, R. M., Cahill, M. R., Kiely, P. A., Porse, Bo Torben & Keeshan, K., 6 Oct 2016, In: Oncogene. 35, 40, p. 5272-5281 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4

    Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

    Ohlsson, E., Schuster, Mikkel Bruhn, Hasemann, M. & Porse, Bo Torben, Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

    Bagger, F. O., Sasivarevic, D., Hadi Sohi, S., Laursen, L. G., Pundhir, Sachin, Sønderby, C. K., Winther, Ole, Rapin, N. & Porse, Bo Torben, 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D917-24 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

    Pundhir, Sachin, Bagger, F. O., Lauridsen, F. K. B., Rapin, N. P. J. & Porse, Bo Torben, 2016, In: Nucleic Acids Research. 44, 9, p. 4037-4051 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts

    Bao, J., Vitting-Seerup, K., Waage, J. E., Tang, C., Ge, Y., Porse, Bo Torben & Yan, W., 2016, In: P L o S Genetics. 12, 5, 24 p., e1005863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2015
  58. Published

    Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F. K. B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B. T. & 2 others, Tanay, A. & Amit, I., 17 Dec 2015, In: Cell. 163, 7, p. 1663-77 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Disease evolution and outcomes in familial AML with germline CEBPA mutations

    Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F. W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K. & 21 others, Bullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, Anne-Katrine, Lauridsen, F. B., Porse, Bo Torben, Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. & Fitzgibbon, J., 3 Sep 2015, In: Blood. 126, 10, p. 1214-23 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

    Rasmussen, K. D., Jia, G., Johansen, Jens Vilstrup, Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, Bo Torben, Bernard, O. A., Christensen, J. & Helin, K., 17 Apr 2015, In: Genes & Development. p. 910-922 13 p., 29.

    Research output: Contribution to journalJournal articleResearchpeer-review

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