Birgitte Rahbek Kornum

Birgitte Rahbek Kornum

Guest Researcher, Associate Professor - Promotion Programme


  1. 2024
  2. Published

    The immunopathogenesis of narcolepsy type 1

    Liblau, R. S., Latorre, D., Kornum, Birgitte Rahbek, Dauvilliers, Y. & Mignot, E. J., 2024, In: Nature Reviews Immunology. 24, p. 33-48

    Research output: Contribution to journalReviewpeer-review

  3. Published

    Downregulation of hypocretin/orexin after H1N1 Pandemrix vaccination of adolescent mice

    Pagh-Berendtsen, Nicolai, Pavlovskyi, A., Flores Téllez, D., Jensen, Christine Egebjerg, Pedersen, Mie Gunni Kolmos, Justinussen, Jessica & Kornum, Birgitte Rahbek, 2024, In: Sleep.

    Research output: Contribution to journalJournal articlepeer-review

  4. 2023
  5. Published

    How hypocretin agonists may improve the quality of wake in narcolepsy

    Justinussen, Jessica, Jensen, Christine Egebjerg & Kornum, Birgitte Rahbek, 2023, In: Trends in Molecular Medicine. 29, 1, p. 61-69 9 p.

    Research output: Contribution to journalReviewpeer-review

  6. Published

    Experimental sickness reduces hypocretin receptor 1 expression in the lateral hypothalamus and ventral tegmental area of female mice

    Pedersen, Mie Gunni Kolmos, Arribas, A. P., Kornum, Birgitte Rahbek & Justinussen, Jessica, 2023, In: European Journal of Neuroscience. 58, 9, p. 4002-4010 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published
  8. Published
  9. Published

    Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

    Ollila, H. M., Sharon, E., Lin, L., Sinnott-Armstrong, N., Ambati, A., Yogeshwar, S. M., Hillary, R. P., Jolanki, O., Faraco, J., Einen, M., Luo, G., Zhang, J., Han, F., Yan, H., Dong, X. S., Li, J., Zhang, J., Hong, S. C., Kim, T. W., Dauvilliers, Y. & 31 others, Barateau, L., Lammers, G. J., Fronczek, R., Mayer, G., Santamaria, J., Arnulf, I., Knudsen-Heier, S., Bredahl, M. K. L., Thorsby, P. M., Plazzi, G., Pizza, F., Moresco, M., Crowe, C., Van den Eeden, S. K., Lecendreux, M., Bourgin, P., Kanbayashi, T., Martínez-Orozco, F. J., Peraita-Adrados, R., Benetó, A., Montplaisir, J., Desautels, A., Huang, Y. S., Jennum, Poul, Nevsimalova, S., Kemlink, D., Iranzo, A., Overeem, S., Wierzbicka, A., Kornum, Birgitte Rahbek & FinnGen, F., 2023, In: Nature Communications. 14, 1, 13 p., 2709.

    Research output: Contribution to journalJournal articlepeer-review

  10. Published
  11. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Repeated measures of hypocretin-1 in Danish and Italian patients with narcolepsy and in controls

    Torstensen, E. W., Haubjerg Østerby, N. C., Pizza, F., Plazzi, G., Antelmi, E., Moresco, M., Mignot, E., Jørgensen, Niklas Rye, Christensen, G. L., Wanscher, B., Kornum, Birgitte Rahbek & Jennum, Poul, 2023, In: Sleep Medicine. 101, p. 213-220 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published

    Repeated polysomnography and multiple sleep latency test in narcolepsy type 1 and other hypersomnolence disorders

    Torstensen, E. W., Haubjerg Østerby, N. C., Kornum, Birgitte Rahbek, Wanscher, B., Mignot, E., Barløse, Mads Christian Johannes & Jennum, Poul, 2023, In: Sleep Medicine. 110, p. 91-98 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  14. Published

    Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings

    Viste, R., Follin, L. F., Kornum, Birgitte Rahbek, Lie, B. A., Viken, M. K., Thorsby, P. M., Rootwelt, T., Christensen, J. A. E. & Knudsen-Heier, S., 2023, In: Sleep. 46, 3, 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published

    Emerging therapeutic targets for narcolepsy

    Vringer, M. & Kornum, Birgitte Rahbek, 2023, In: Expert Opinion On Therapeutic Targets. 25, 7, p. 559-572 14 p.

    Research output: Contribution to journalReviewpeer-review

  16. 2022
  17. Published

    Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

    Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

    Research output: Contribution to journalJournal articlepeer-review

  18. Published

    The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio

    Holm, A., Possovre, M. L., Bandarabadi, M., Moseholm, Kristine Frøsig, Justinussen, Jessica, Bozic, I., Lemcke, René, Arribat, Y., Amati, F., Silahtaroglu, Asli, Juventin, M., Adamantidis, A., Tafti, M. & Kornum, Birgitte Rahbek, 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 17, 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  19. Published

    Neurobioloy of sleep and circadian disorders

    Kornum, Birgitte Rahbek & Mignot, E., 2022, Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition. M. J. Z., C. A. W. & M-F. C. (eds.). 2 ed. Elsevier, p. 635-658 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Sex-related differences within sleep-wake dynamics, cataplexy, and EEG fast-delta power in a narcolepsy mouse model

    Petersen, Louise Piilgaard, Rose, Laura, Hviid, C. G., Kohlmeier, Kristi Anne & Kornum, Birgitte Rahbek, 2022, In: Sleep. 45, 7, 15 p., zsac058.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients have increased muscle activity during REM and nrem sleep compared with their non-narcoleptic siblings

    Viste, R., Lie, B. A., Kornum, Birgitte Rahbek, Rootwelt, T. & Knudsen-Heier, S., 2022, In: Journal of Sleep Research. 31, Supplement 1, 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  22. 2021
  23. Published

    Pre-treatment of blood samples reveal normal blood hypocretin/orexin signal in narcolepsy type I

    Aegidius, H. M., Kruse, L., Christensen, G. L., Lorentzen, M. P., Jørgensen, Niklas Rye, Moresco, M., Pizza, F., Plazzi, G., Jennum, Poul & Kornum, Birgitte Rahbek, 2021, In: Brain Communications. 3, 2, 13 p., 050.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Narcolepsy Type I as an autoimmune disorder

    Kornum, Birgitte Rahbek, 2021, Handbook of Clinical Neurology. 1 ed. Elsevier, p. 161-172 12 p. (Handbook of Clinical Neurology, Vol. 181).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  25. Published

    GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

    Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    GABAA receptor β1-subunit knock-out mice show increased delta power in NREM sleep and decreased theta power in REM sleep

    Lie, M. E. K., Falk-Petersen, C. B., Petersen, Louise Piilgaard, Griem-Krey, Nane, Wellendorph, Petrine & Kornum, Birgitte Rahbek, 2021, In: European Journal of Neuroscience. 54, 2, p. 4445-4455 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Diagnostic value of actigraphy in hypersomnolence disorders

    Torstensen, E. W., Pickering, L., Kornum, Birgitte Rahbek, Wanscher, B., Baandrup, Lone & Jennum, Poul, 2021, In: Sleep Medicine. 85, p. 1-7 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published

    High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11protein levels in narcolepsy type 1

    Viste, R., Viken, M. K., Lie, B. A., Juvodden, H. T., Nordstrand, S. E. H., Thorsby, P. M., Rootwelt, T., Kornum, Birgitte Rahbek & Knudsen-Heier, S., 2021, In: Sleep. 44, 8, 12 p., zsab062.

    Research output: Contribution to journalJournal articlepeer-review

  29. Published

    Narcolepsy type 1 patients have lower levels of effector memory CD4+ T cells compared to their siblings when controlling for H1N1-(Pandemrix™)-vaccination and HLA DQB1∗06:02 status

    Viste, R., Lie, B. A., Viken, M. K., Rootwelt, T., Knudsen-Heier, S. & Kornum, Birgitte Rahbek, 2021, In: Sleep Medicine. 85, p. 271-279 9 p.

    Research output: Contribution to journalJournal articlepeer-review

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ID: 143987587