Birgitte Holst
Guest Researcher
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- Published
Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery
Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway
Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340Research output: Contribution to journal › Journal article › peer-review
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Anorexia and fat aversion induced by vertical sleeve gastrectomy is attenuated in neurotensin receptor 1–Deficient mice
Ratner, C., Shin, J. H., Dwibedi, C., Tremaroli, V., Bjerregaard, Anette, Hartmann, Bolette, Bäckhed, F., Leinninger, G., Seeley, R. J. & Holst, Birgitte, 2021, In: Endocrinology. 162, 9, 12 p., bqab130.Research output: Contribution to journal › Journal article › peer-review
- Published
The metabolic actions of neurotensin secreted from the gut
Ratner, C., Johnsen, Cecilie Hundahl & Holst, Birgitte, Sep 2016, In: Cardiovascular Endocrinology. 5, 3, p. 102-111Research output: Contribution to journal › Review › peer-review
- Published
Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity
Ratner, C., Madsen, A. N., Kristensen, L. V., Skov, Louise Julie, Pedersen, K. S., Mortensen, Ole Hartvig, Knudsen, Gitte Moos, Raun, K. & Holst, Birgitte, 8 Apr 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 308, 11, p. R973-R982 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor
Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.Research output: Contribution to journal › Journal article › peer-review
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Ghrelin-mediated improvements in the metabolic phenotype in the R6/2 mouse model of Huntington's disease
Rudenko, Olga, Springer, C., Skov, Louise Julie, Madsen, A. N., Hasholt, Lis Frydenreich, Nørremølle, Anne & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7 (SI), 14 p., e12699.Research output: Contribution to journal › Conference article › peer-review
- Published
Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors
Schwartz, Thue W. & Holst, Birgitte, 2006, In: Journal of Receptors and Signal Transduction. 26, 1-2, p. 107-28 21 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Allosteric enhancers, allosteric agonists and ago-allosteric modulators: where do they bind and how do they act?
Schwartz, Thue W. & Holst, Birgitte, 2007, In: TIPS - Trends in Pharmacological Sciences. 28, 8, p. 366-73 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Molecular mechanism of 7TM receptor activation--a global toggle switch model
Schwartz, Thue W., Frimurer, T. M., Holst, Birgitte, Rosenkilde, Mette & Elling, C. E., 2006, In: Annual Review of Pharmacology and Toxicology. 46, p. 481-519 38 p.Research output: Contribution to journal › Journal article › peer-review
- Published
An enteroendocrine full package solution
Schwartz, Thue W. & Holst, Birgitte, 2010, In: Cell Metabolism. 11, 6, p. 445-7 2 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Molecular structure and function of 7TM/G-protein coupled receptors
Schwartz, Thue W. & Holst, Birgitte, 2002, Textbook of receptor Pharmacology. p. 65-84Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- Published
Risperidone treatment increases CB1 receptor binding in rat brain
Secher, A., Husum, H., Holst, Birgitte, Egerod, Kristoffer Lihme & Mellerup, Erling Thyge, 2010, In: Neuroendocrinology. 91, 2, p. 155-68 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A systematic review and meta-analysis finds increased blood levels of all forms of ghrelin in both restricting and binge-eating/purging subtypes of anorexia nervosa
Seidel, M., Jensen, S. M., Healy, D., Dureja, A., Watson, H. J., Holst, Birgitte, Bulik, C. M. & Sjögren, J. M., 2021, In: Nutrients. 13, 2, p. 1-19 19 p., 709.Research output: Contribution to journal › Review › peer-review
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Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor
Sivertsen, B., Holliday, N., Madsen, A. N. & Holst, Birgitte, Dec 2013, In: British Journal of Pharmacology. 170, 7, p. 1349-62 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Unique interaction pattern for a functionally biased ghrelin receptor agonist
Sivertsen, B. B., Lang, M., Frimurer, T. M., Holliday, N. D., Bach, Anders, Els, S., Engelstoft, M. S., Petersen, P. S., Madsen, A. N., Schwartz, Thue W., Beck-Sickinger, A. G. & Holst, Birgitte, 10 Jun 2011, In: The Journal of Biological Chemistry. 286, 23, p. 20845-20860 16 p.Research output: Contribution to journal › Journal article › peer-review
- Published
RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › peer-review
- Published
Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area
Skov, Louise Julie, Jensen, M., Christiansen, S. H., Ratner, C., Woldbye, David Paul Drucker & Holst, Birgitte, 26 Apr 2017, In: International Journal of Molecular Sciences. 18, 5, 17 p., 914.Research output: Contribution to journal › Journal article › peer-review
- Published
Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes
Steenberg, V. R., Jensen, S. M., Pedersen, Jens, Madsen, A. N., Windeløv, Johanne Agerlin, Holst, Birgitte, Quistorff, B., Poulsen, Steen Seier & Holst, Jens Juul, 2016, In: Diabetologia. 59, 2, p. 363-370 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39
Storjohann, L., Holst, Birgitte & Schwartz, Thue W., 2008, In: FEBS Letters. 582, 17, p. 2583-8 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39
Storjohann, L., Holst, Birgitte & Schwartz, Thue W., 2008, In: Biochemistry. 47, 35, p. 9198-207 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
New potential agents for cryopreservation of hematopoietic and adipose stromal cells
Svalgaard, J., Haastrup, E., Brink, A., Clausen, C., Holst, Birgitte, Theilgaard-Mønch, Kim, Reckzeh, K. & Fischer-Nielsen, A., Apr 2014, In: Cytotherapy. 16, Supplement 4, p. S58Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Physiological and Pathological Impact of Blood Sampling by Retro-Bulbar Sinus Puncture and Facial Vein Phlebotomy in Laboratory Mice
Teilmann, A. C., Nygaard Madsen, A., Holst, Birgitte, Hau, Jann, Rozell, B. & Abelson, Klas, 26 Nov 2014, In: PloS one. 9, 11, p. 1-19 19 p., e113225.Research output: Contribution to journal › Journal article › peer-review
- Published
High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice
Thieme, V., Jolly, N., Madsen, A. N., Bellmann-Sickert, K., Schwartz, Thue W., Holst, Birgitte, Cox, H. M. & Beck-Sickinger, A. G., Nov 2016, In: British Journal of Pharmacology. 173, 22, p. 3208-3221 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Metabolic insights from a GHSR-A203E mutant mouse model
Pedersen, Lola Julie Torz, Osborne-Lawrence, S., Rodriguez, J., He, Z., Paula Cornejo, M., Roman Mustafa, E., Jin, C., Petersen, N., Hedegaard, M. A., Nybo, Maja Lind, Martinez Damonte, V., Metzger, N. P., Mani, B. K., Williams, K. W., Raingo, J., Perello, M., Holst, Birgitte & Zigman, J. M., 2020, In: Molecular Metabolism. 39, 16 p., 101004.Research output: Contribution to journal › Journal article › peer-review
ID: 9886
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Dietary non-esterified oleic Acid decreases the jejunal levels of anorectic N-acylethanolamines
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance
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