Birgitte Holst
Guest Researcher
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor
Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 22, p. 12322-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conversion of agonist site to metal-ion chelator site in the ¿2-adrenergic receptor
Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, no. 22, p. 12322-12327Research output: Contribution to journal › Journal article › Research › peer-review
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Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism
Petersen, P. S., Jin, C., Madsen, A. N., Rasmussen, M., Kuhre, Rune Ehrenreich, Egerod, Kristoffer Lihme, Nielsen, L. B., Schwartz, Thue W. & Holst, Birgitte, 22 Jul 2011, In: FASEB Journal. p. 3803-3814 12 p., 4.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of potent and proteolytically stable human neuromedin U receptor agonists
De Prins, A., Martin, C., Van Wanseele, Y., Skov, Louise Julie, Tömböly, C., Tourwé, D., Caveliers, V., Van Eeckhaut, A., Holst, Birgitte, Rosenkilde, Mette, Smolders, I. & Ballet, S., 20 Jan 2018, In: European Journal of Medicinal Chemistry. 144, p. 887-897 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor
Diep, T. A., Madsen, A. N., Holst, Birgitte, Kristiansen, M. M., Andersen, N. W., Hansen, S. H. & Hansen, Harald S., 2011, In: The FASEB Journal. 25, 2, p. 765-774Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary non-esterified oleic Acid decreases the jejunal levels of anorectic N-acylethanolamines
Diep, T. A., Madsen, A. N., Krogh-Hansen, S., Al-Shahwani, M., Al-Sabagh, L., Holst, Birgitte & Hansen, Harald S., 2014, In: PloS one. 9, 6, p. 1-7 7 p., e100365.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting
Heydorn, A., Søndergaard, B. P., Hadrup, N., Holst, Birgitte, Haft, C. R. & Schwartz, Thue W., 2004, In: FEBS Letters. 556, 1-3, p. 276-80 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines
Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, , 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery
Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Estrous Cycle Modulation of Feeding and Relaxin-3/Rxfp3 mRNA Expression: Implications for Estradiol Action
de Avila, C., Chometton, S., Calvez, J., Guevremont, G., Kania, A., Pedersen, Lola Julie Torz, Lenglos, C., Blasiak, A., Rosenkilde, Mette, Holst, Birgitte, Conrad, C. D., Fyer, J. D., Timofeeva, E., Gundlach, A. L. & Cifani, C., 2021, In: Neuroendocrinology. 111, 12, p. 1201–1218Research output: Contribution to journal › Journal article › Research › peer-review
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Exogenous LEAP2 improves postprandial glucose tolerance and reduces ad libitum food intake in men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Heimburger, S. M. N., Dela, Flemming, Vilsbøll, Tina, Holst, Birgitte & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 23-23 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area
Skov, Louise Julie, Jensen, M., Christiansen, S. H., Ratner, C., Woldbye, David Paul Drucker & Holst, Birgitte, 26 Apr 2017, In: International Journal of Molecular Sciences. 18, 5, 17 p., 914.Research output: Contribution to journal › Journal article › Research › peer-review
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FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver
von Holstein-Rathlou, S., BonDurant, L. D., Peltekian, L., Naber, M. C., Yin, T. C., Claflin, K. E., Urizar, A. I., Madsen, A. N., Ratner, C., Holst, B., Karstoft, K., Vandenbeuch, A., Anderson, C. B., Cassell, M. D., Thompson, A. P., Solomon, T. P., Rahmouni, K., Kinnamon, S. C., Pieper, A. A., Gillum, M. P. & 1 others, , 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 335-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, , 2010, In: P L o S One. 5, 4, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus
de Guia, R. M., Hassing, Anna Skab, Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4Research output: Contribution to journal › Journal article › Research › peer-review
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Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population
Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor
Sivertsen, B., Holliday, N., Madsen, A. N. & Holst, Birgitte, Dec 2013, In: British Journal of Pharmacology. 170, 7, p. 1349-62 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction
Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)
Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 (zinc receptor) knockout mice exhibit depression-like behavior and CREB/BDNF down-regulation in the hippocampus
Młyniec, K., Budziszewska, B., Holst, Birgitte, Ostachowicz, B. & Nowak, G., 2015, In: International Journal of Neuropsychopharmacology. 18, 3, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 signaling is stimulated by zinc ions but not by obestatin
Holst, Birgitte, Egerod, Kristoffer Lihme, Schild, E., Vickers, S. P., Cheetham, S., Gerlach, L., Storjohann, L., Stidsen, C. E., Jones, R., Beck-Sickinger, A. G. & Schwartz, Thue W., 2006, In: Endocrinology. 148, 1, p. 13-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue.
Egerod, Kristoffer Lihme, Holst, Birgitte, Petersen, P. S., Hansen, Jacob B., Mulder, J., Hökfelt, T. & Schwartz, Thue W., 2007, In: Molecular Endocrinology. 21, 7, p. 1685-98 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo
Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 Zn2+-sensing receptor: a new target in antidepressant development?
Młyniec, K., Singewald, N., Holst, Birgitte & Nowak, G., 15 Mar 2015, In: Journal of Affective Disorders. 174, p. 89-100 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ghrelin
Mueller, T. D., Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., Batterham, R. L., Benoit, S. C., Bowers, C. Y., Broglio, F., Casanueva, F. F., D'Alessio, D., Depoortere, I., Geliebter, A., Ghigo, E., Cole, P. A., Cowley, M., Cummings, D. E., Dagher, A., Diano, S. & 37 others, , Jun 2015, In: Molecular Metabolism. 4, 6, p. 437-460 24 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 9886
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4607
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Dietary non-esterified oleic Acid decreases the jejunal levels of anorectic N-acylethanolamines
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
4511
downloads
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2903
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PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance
Research output: Contribution to journal › Journal article › Research › peer-review
Published