Birgitte Brock

Birgitte Brock

Clinical Associate Professor


  1. Published

    Cardiac vagal tone, a non-invasive measure of parasympathetic tone, is a clinically relevant tool in Type 1 diabetes mellitus

    Brock, C., Jessen, N., Brock, Birgitte, Jakobsen, P. E., Hansen, T. K., Rantanen, Jukka, Riahi, S., Dimitrova, Y. K., Dons-Jensen, A., Aziz, Q., Drewes, A. M. & Farmer, A. D., Oct 2017, In: Diabetic Medicine. 34, 10, p. 1428-1434 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Vagal Nerve Stimulation-Modulation of the Anti-Inflammatory Response and Clinical Outcome in Psoriatic Arthritis or Ankylosing Spondylitis

    Brock, C., Rasmussen, S. E., Drewes, A. M., Møller, H. J., Brock, Birgitte, Deleuran, B., Farmer, A. D. & Pfeiffer-Jensen, M., 2021, In: Mediators of Inflammation. 2021, 9 p., 9933532.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Liraglutide treatment reduced interleukin-6 in adults with type 1 diabetes but did not improve established autonomic or polyneuropathy

    Brock, C., Hansen, C. S., Karmisholt, J., Møller, H. J., Juhl, A., Farmer, A. D., Drewes, A. M., Riahi, S., Lervang, H. H., Jakobsen, P. E. & Brock, Birgitte, 2019, In: British Journal of Clinical Pharmacology. 85, 11, p. 2512-2523 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Oral administration of sitagliptin activates CREB and is neuroprotective in murine model of brain trauma

    Della Valle, B. W., Brix, G. S., Brock, Birgitte, Geji, M., Rungby, J. & Larsen, A., 1 Dec 2016, In: Frontiers in Pharmacology. 7, 8 p., 450.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Short-term transcutaneous non-invasive vagus nerve stimulation may reduce disease activity and pro-inflammatory cytokines in rheumatoid arthritis: results of a pilot study

    Drewes, A., Brock, C., Rasmussen, S., Møller, H., Brock, Birgitte, Deleuran, B., Farmer, A. & Pfeiffer-jensen, M., 2 Jan 2021, In: Scandinavian Journal of Rheumatology. 50, 1, p. 20-27 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial

    Egefjord, L., Gejl, M., Møller, P. A., Brændgaard, H., Gottrup, H., Antropova, O., Møller, N., Poulsen, Henrik Enghusen, Gjedde, Albert, Brock, Birgitte & Rungby, J., Oct 2012, In: Danish Medical Bulletin (Online). 59, 10, p. A4519

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Diabetes

    Felding, P., Jensen, I., Manford, G., Linnet, Kristian, Stahl, M., Jørgensen, L. G. M., Hyltoft Petersen, P., Brandslund, I., Olivarius de Fine, N., Borch-Johnsen, K., Ivanov, A., Zemtsovskaja, G., Nerhus, K., Kristensen, G., Sandberg, S., Brock, Birgitte, Gregersen, S. & Hermansen, K., 1 Jan 2000, In: Scandinavian Journal of Clinical and Laboratory Investigation, Supplement. 60, 232, p. 96-98 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    In Alzheimer's disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: Randomized, placebo-controlled, double-blind clinical trial

    Gejl, M., Gjedde, Albert, Egefjord, L., Møller, A., Hansen, S. B., Vang, K., Rodell, A., Brændgaard, H., Gottrup, H., Schacht, A. C., Møller, N., Brock, Birgitte & Rungby, Jørgen, 2016, In: Frontiers in Aging Neuroscience. 8, 10 p., 108.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia

    Gejl, M., Lerche, S., Mengel, A., Møller, N., Bibby, B. M., Smidt, K., Brock, Birgitte, Søndergaard, H., Bøtker, H. E., Gjedde, Albert, Holst, Jens Juul, Hansen, S. B. & Rungby, J., 2014, In: PLOS ONE. 9, 1, p. 1-10 10 p., e83758.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    At the centennial of Michaelis and Menten, competing Michaelis-Menten steps explain effect of GLP-1 on blood-brain transfer and metabolism of glucose

    Gejl, M., Rungby, J., Brock, Birgitte & Gjedde, Albert, Aug 2014, In: Basic & Clinical Pharmacology & Toxicology. 115, 2, p. 162-71 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial

    Gejl, M., Gjedde, Albert, Brock, Birgitte, Møller, A., van Duinkerken, E., Haahr, H. L., Hansen, C. T., Chu, P. L., Stender-Petersen, K. L. & Rungby, Jørgen, Mar 2018, In: Diabetologia. 61, 3, p. 551–561

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Glucagon-like peptide-1 (GLP-1) raises blood-brain glucose transfer capacity and hexokinase activity in human brain

    Gejl, M., Lerche, S., Egefjord, L., Brock, Birgitte, Møller, N., Vang, K., Rodell, A., Bibby, B. M., Holst, Jens Juul, Rungby, J. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-9 10 p., 2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Blood-Brain Glucose Transfer in Alzheimer's disease: Effect of GLP-1 Analog Treatment

    Gejl, M., Brock, Birgitte, Egefjord, L., Vang, K., Rungby, Jørgen & Gjedde, Albert, Dec 2017, In: Scientific Reports. 7, 1, 10 p., 17490.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Impact of glucagon-like peptide-1 on myocardial glucose metabolism revisited

    Hansen, J., Brock, Birgitte, Bøtker, H. E., Gjedde, Albert, Rungby, J. & Gejl, M., Sep 2014, In: Reviews in Endocrine and Metabolic Disorders. 15, 3, p. 219-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes

    Hansen, T. M., Brock, Birgitte, Juhl, A., Drewes, A. M., Vorum, H., Andersen, C. U., Jakobsen, P. E., Karmisholt, J., Frokjaer, J. B. & Brock, C., Apr 2019, In: Journal of Diabetes and its Complications. 33, 4, p. 323-328

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells

    Maxel, T., Smidt, K., Petersen, C. C., Honoré, B., Christensen, A. K., Jeppesen, P. B., Brock, Birgitte, Rungby, Jørgen, Palmfeldt, J. & Larsen, A., 2019, In: Scientific Reports. 9, 1, 15 p., 8589.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Pathophysiology and management of diabetic gastroenteropathy

    Meldgaard, T., Keller, J., Olesen, A. E., Olesen, S. S., Krogh, K., Borre, M., Farmer, A., Brock, Birgitte, Brock, C. & Drewes, A. M., Jun 2019, In: Therapeutic Advances in Gastroenterology. 12, p. 1-17

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    The effects of incretin hormones on cerebral glucose metabolism in health and disease

    Nilsson, M., Gjedde, Albert, Brock, Birgitte, Gejl, M. & Rungby, Jørgen, 2018, In: Neuropharmacology. 136, Part B, p. 243-250 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Peripheral, synaptic and central neuronal transmission is affected in type 1 diabetes

    Nissen, T. D., Meldgaard, T., Nedergaard, R. W., Juhl, A. H., Jakobsen, P. E., Karmisholt, J., Drewes, A. M., Brock, Birgitte & Brock, C., 2020, In: Journal of Diabetes and its Complications. 34, 9, 107614.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes

    Okdahl, T., Brock, C., Floyel, T., Wegeberg, A. L., Jakobsen, P. E., Ejskjaer, N., Pociot, Flemming, Brock, Birgitte & Størling, Joachim, 2020, In: Clinical Endocrinology. 93, 4, p. 419-428

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Study protocol for a multicentre, randomised, parallel group, sham-controlled clinical trial investigating the effect of transcutaneous vagal nerve stimulation on gastrointestinal symptoms in people with diabetes complicated with diabetic autonomic neuropathy: The DAN-VNS Study

    Okdahl, T., Bertoli, D., Brock, Birgitte, Krogh, K., Krag Knop, F., Brock, C. & Drewes, A. M., 2021, In: BMJ Open. 11, 1, e038677.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen

    Thorsted, A., Kristoffersson, A. N., Maarbjerg, S. F., Schrøder, H., Wang, M., Brock, Birgitte, Nielsen, E. I. & Friberg, L. E., 2019, In: The Journal of antimicrobial chemotherapy. 74, 10, p. 2984-2993 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Cardiac vagal tone as a novel screening tool to recognize asymptomatic cardiovascular autonomic neuropathy: Aspects of utility in type 1 diabetes

    Wegeberg, A. M., Lunde, E. D., Riahi, S., Ejskjaer, N., Drewes, A. M., Brock, Birgitte, Pop-Busui, R. & Brock, C., 2020, In: Diabetes Research and Clinical Practice. 170, 108517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Quantities of comorbidities affects physical, but not mental health related quality of life in type 1 diabetes with confirmed polyneuropathy

    Wegeberg, A. L., Meldgaard, T., Hyldahl, S., Jakobsen, P. E., Drewes, A. M., Brock, Birgitte & Brock, C., 2019, In: World Journal of Diabetes. 10, 2, p. 87-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes

    Wegeberg, A. L., Okdahl, T., Fløyel, T., Brock, C., Ejskjaer, N., Riahi, S., Pociot, Flemming, Størling, Joachim & Brock, Birgitte, 2020, In: Mediators of Inflammation. 2020, 10 p., 3590389.

    Research output: Contribution to journalJournal articleResearchpeer-review

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