Benjamin Skov Kaas-Hansen

Benjamin Skov Kaas-Hansen

Assistant lecturer


  1. 2024
  2. Published

    Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock—Bayesian analyses of the CLASSIC trial

    Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Kaas-Hansen, Benjamin Skov, Kjær, M. B. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 2, p. 236-246 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. 2023
  4. Published

    Abnormal serum levels of magnesium, phosphate, and zinc in ICU patients—Characteristics, management, and outcomes: The WhyTrace cohort study

    Vesterlund, G. K., Thorsen-Meyer, H. C., Møller, Morten Hylander, Brunak, Søren, Strøm, T., Perner, Anders & Kaas-Hansen, Benjamin Skov, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 925-935 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    An overview of methodological considerations regarding adaptive stopping, arm dropping and randomisation in clinical trials

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Schjørring, O. L., Andersen, L. W., Perner, Anders, Jensen, Aksel Karl Georg & Møller, Morten Hylander, 2023, In: Journal of Clinical Epidemiology. 153, p. 45-54 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Association between days alive without life support/out of hospital and health-related quality of life

    Granholm, A., Schjorring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strom, T., Lange, Theis, Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 762-771 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Development of a dynamic prediction model for unplanned ICU admission and mortality in hospitalized patients

    Placido, Davide, Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, Reguant, R. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 6, 18 p., e0000116.

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    Effects of duration of follow-up and lag in data collection on the performance of adaptive clinical trials

    Granholm, A., Lange, Theis, Harhay, M. O., Jensen, Aksel Karl Georg, Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2023, In: Pharmaceutical Statistics. 23, 2, p. 138-150 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Exploratory pharmacovigilance with machine learning in big patient data: a focused scoping review

    Kaas-Hansen, Benjamin Skov, Gentile, S., Caioli, A. & Andersen, Stig Ejdrup, 2023, In: Basic & clinical pharmacology & toxicology. 132, 3, p. 233-241 9 p.

    Research output: Contribution to journalReviewpeer-review

  10. Published

    Health-related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study

    Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Møller, Morten Hylander, Jensen, Aksel Karl Georg, Larsen, M. E., Cuthbertson, B. H., Perner, Anders & Granholm, A., 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Platform trials: Platformsforsøg

    Perner, A., Kjær, M. B. N., Thorsen-Meyer, H. C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. R., Jensen, A. K., Lange, T., Albertsen, T., Pedersen, C. D., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., Rasmussen, B. S., Schjørring, O. L., Maagaard, M. & 2 others, Møller, Morten Hylander & Granholm, A., 2023, In: Ugeskrift for Laeger. 185, 41, 10 p.

    Research output: Contribution to journalReviewpeer-review

  12. Published

    Real-world causal evidence for planned predictive enrichment in critical care trials: A scoping review

    Kaas-Hansen, Benjamin Skov, Granholm, A., Sivapalan, P., Anthon, C. T., Schjørring, O. L., Maagaard, M., Kjaer, M. N., Mølgaard, J., Ellekjaer, K. L., Fagerberg, S. K., Lange, Theis, Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 16-25 10 p.

    Research output: Contribution to journalReviewpeer-review

  13. Published

    Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Munch, M. W., Harhay, M. O., Zampieri, F. G., Perner, Anders, Møller, Morten Hylander & Jensen, Aksel Karl Georg, 2023, In: BMC Medical Research Methodology. 23, 1, 12 p., 139.

    Research output: Contribution to journalJournal articlepeer-review

  14. 2022
  15. Published

    Causal inference for planning randomised critical care trials: protocol for a scoping review

    Kaas-Hansen, Benjamin Skov, Granholm, A., Anthon, C. T., Kjær, M. N., Sivapalan, P., Maagaard, M., Schjørring, O. L., Fagerberg, S. K., Ellekjær, K. L., Mølgaard, J., Ekstrøm, Claus Thorn, Møller, Morten Hylander & Perner, Anders, Oct 2022, In: Acta Anaesthesiologica Scandinavica. 66, 10, p. 1274–1278 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  16. Published

    Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?

    Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.

    Research output: Contribution to journalJournal articlepeer-review

  17. Published
  18. Published

    Design considerations in clinical trials with adaptive stopping, arm-dropping and randomisation

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, T., Schjorring, O., Andersen, L., Perner, Anders, Jensen, A. & Møller, M., 2022, p. S88-S89. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  19. Published
  20. Published

    Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data

    Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, Annelaura Bach, Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.

    Research output: Contribution to journalJournal articlepeer-review

  21. Published

    Drug interactions in hospital prescriptions in Denmark: Prevalence and associations with adverse outcomes

    Rodríguez, C. L., Kaas-Hansen, Benjamin Skov, Eriksson, R., Biel, J. H., Belling, K. G., Andersen, Stig Ejdrup & Brunak, Søren, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 6, p. 632-642 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Eliciting drug safety signals from patient records: a language-agnostic approach

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodriguez, C., Thorsen-Meyer, H., Gentile, S., Nielsen, A., Brunak, Søren, Jürgens, Gesche & Andersen, S., 2022, p. S15-S16. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  23. Published

    Health-related quality of life and days alive without life support or out of hospital: protocol

    Granholm, A., Schjørring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strøm, T., Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 2, p. 295-301 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodríguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, In: Basic & clinical pharmacology & toxicology. 131, 4, p. 282-293 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Language-agnostic pharmacovigilant text mining to elicit side effects from clinical notes and hospital medication records

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodrìguez, C. L., Thorsen-Meyer, H., Gentile, S., Nielsen, A. P., Brunak, Søren, Jürgens, Gesche & Andersen, Stig Ejdrup, 2022, Authorea, (Authorea Preprints).

    Research output: Working paperPreprintResearch

  26. Published

    Machine Learning to Identify Patients at Risk of Inappropriate Dosing for Renal Risk Medications: A Critical Comment on Kaas-Hansen et al [Response to Letter]

    Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 765-766 2 p.

    Research output: Contribution to journalComment/debate

  27. Published

    Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review

    Granholm, A., Anthon, C. T., Kjær, M. N., Maagaard, M., Kaas-Hansen, Benjamin Skov, Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2022, In: Critical Care Medicine. 50, 10, p. e759-e771 13 p.

    Research output: Contribution to journalReviewpeer-review

  28. Published

    Pharmacovigilant Machine Learning in Big Data?

    Kaas-Hansen, Benjamin Skov, 2022

    Research output: Book/ReportPh.D. thesis

  29. Published

    Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international network

    Williams, R. D., Markus, A. F., Yang, C., Duarte-Salles, T., DuVall, S. L., Falconer, T., Jonnagaddala, J., Kim, C., Rho, Y., Williams, A. E., Machado, A. A., An, M. H., Aragón, M., Areia, C., Burn, E., Choi, Y. H., Drakos, I., Abrahão, M. T. F., Fernández-Bertolín, S., Hripcsak, G. & 28 others, Kaas-Hansen, Benjamin Skov, Kandukuri, P. L., Kors, J. A., Kostka, K., Liaw, S., Lynch, K. E., Machnicki, G., Matheny, M. E., Morales, D., Nyberg, F., Park, R. W., Prats-Uribe, A., Pratt, N., Rao, G., Reich, C. G., Rivera, M., Seinen, T., Shoaibi, A., Spotnitz, M. E., Steyerberg, E. W., Suchard, M. A., You, S. C., Zhang, L., Zhou, L., Ryan, P. B., Prieto-Alhambra, D., Reps, J. M. & Rijnbeek, P. R., 2022, In: BMC Medical Research Methodology. 22, 13 p., 35.

    Research output: Contribution to journalJournal articlepeer-review

  30. Published

    Using Machine Learning to Identify Patients at High Risk of Inappropriate Drug Dosing in Periods with Renal Dysfunction

    Kaas-Hansen, Benjamin Skov, Leal Rodríguez, C., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2022, In: Clinical Epidemiology. 14, p. 213-223 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    adaptr: an R package for simulating and comparing adaptive clinical trials

    Granholm, A., Jensen, Aksel Karl Georg, Lange, Theis & Kaas-Hansen, Benjamin Skov, 2022, In: Journal of Open Source Software. 7, 72, 1 p., 4284.

    Research output: Contribution to journalJournal articlepeer-review

  32. 2021
  33. Published

    Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

    Jimenez-Solem, E., Petersen, T. S., Hansen, C., Hansen, C., Lioma, C., Igel, C., Boomsma, W., Krause, O., Lorenzen, S., Selvan, R., Petersen, J., Nyeland, M. E., Ankarfeldt, M. Z., Virenfeldt, G. M., Winther-Jensen, M., Linneberg, A., Ghazi, M. M., Detlefsen, N., Lauritzen, A. D., Smith, A. G. & 15 others, de Bruijne, Marleen, Ibragimov, Bulat, Petersen, Jens, Lillholm, Martin, Middleton, Jon Anthony, Mogensen, S. H., Thorsen-Meyer, H., Perner, Anders, Helleberg, M., Kaas-Hansen, Benjamin Skov, Bonde, M., Bonde, A., Pai, A., Nielsen, Mads & Sillesen, Martin Hylleholt, 2021, In: Scientific Reports. 11, 1, 12 p., 3246.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    Identifying patients at high risk of inappropriate drug dosing in periods with renal dysfunction

    Kaas-Hansen, Benjamin Skov, Rodriguez, C. L., Placido, Davide, Thorsen-Meyer, H., Nielsen, A. P., Dérian, N., Brunak, Søren & Andersen, Stig Ejdrup, 2021, medRxiv.

    Research output: Working paperPreprintResearch

  35. Published

    Implementation of the COVID-19 Vulnerability Index Across an International Network of Health Care Data Sets: Collaborative External Validation Study

    Reps, J. M., Kim, C., Williams, R. D., Markus, A. F., Yang, C., Salles, T. D., Falconer, T., Jonnagaddala, J., Williams, A., Fernández-Bertolín, S., DuVall, S. L., Kostka, K., Rao, G., Shoaibi, A., Ostropolets, A., Spotnitz, M. E., Zhang, L., Casajust, P., Steyerberg, E. W., Nyberg, F. & 16 others, Kaas-Hansen, Benjamin Skov, Choi, Y. H., Morales, D., Liaw, S., Abrahão, M. T. F., Areia, C., Matheny, M. E., Aragón, M., Park, R. W., Hripcsak, G., Reich, C. G., Suchard, M. A., You, S. C., Ryan, P. B., Prieto-Alhambra, D. & Rijnbeek, P. R., 2021, In: J M I R Medical Informatics. 9, 4, 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Patient-important outcomes other than mortality in recent ICU trials: protocol for a scoping review

    Granholm, A., Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Anthon, C. T., Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 7, p. 1002-1007 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Risk of depression, suicide and psychosis with hydroxychloroquine treatment for rheumatoid arthritis: a multinational network cohort study

    Lane, J. C. E., Weaver, J., Kostka, K., Duarte-Salles, T., Abrahao, M. T. F., Alghoul, H., Alser, O., Alshammari, T. M., Areia, C., Biedermann, P., Banda, J. M., Burn, E., Casajust, P., Fister, K., Hardin, J., Hester, L., Hripcsak, G., Kaas-Hansen, B. S., Khosla, S., Kolovos, S. & 29 others, Lynch, K. E., Makadia, R., Mehta, P. P., Morales, D. R., Morgan-Stewart, H., Mosseveld, M., Newby, D., Nyberg, F., Ostropolets, A., Woong Park, R., Prats-Uribe, A., Rao, G. A., Reich, C., Rijnbeek, P., Sena, A. G., Shoaibi, A., Spotnitz, M., Vignesh, S., Suchard, M. A., Vizcaya, D., Wen, H., de Wilde, M., Xie, J., You, S. C., Zhang, L., Lovestone, S., Ryan, P., Prieto-Alhambra, D. & OHDSI-COVID-19 consortium, O. C., 2021, In: Rheumatology. 60, 7, p. 3222–3234 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. 2020
  39. Published

    Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia: A Randomized Clinical Trial

    Jürgens, Gesche, Andersen, Stig Ejdrup, Rasmussen, H. B., Werge, Thomas, Jensen, H. D., Kaas-Hansen, Benjamin Skov & Nordentoft, Merete, 1 Dec 2020, In: JAMA Network Open. 3, 12, p. e2027909

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study

    Burn, E., You, S. C., Sena, A. G., Kostka, K., Abedtash, H., Abrahão, M. T. F., Alberga, A., Alghoul, H., Alser, O., Alshammari, T. M., Aragon, M., Areia, C., Banda, J. M., Cho, J., Culhane, A. C., Davydov, A., DeFalco, F. J., Duarte-Salles, T., DuVall, S., Falconer, T. & 49 others, Fernandez-Bertolin, S., Gao, W., Golozar, A., Hardin, J., Hripcsak, G., Huser, V., Jeon, H., Jing, Y., Jung, C. Y., Kaas-Hansen, Benjamin Skov, Kaduk, D., Kent, S., Kim, Y., Kolovos, S., Lane, J. C. E., Lee, H., Lynch, K. E., Makadia, R., Matheny, M. E., Mehta, P. P., Morales, D. R., Natarajan, K., Nyberg, F., Ostropolets, A., Park, R. W., Park, J., Posada, J. D., Prats-Uribe, A., Rao, G., Reich, C., Rho, Y., Rijnbeek, P., Schilling, L. M., Schuemie, M., Shah, N. H., Shoaibi, A., Song, S., Spotnitz, M., Suchard, M. A., Swerdel, J. N., Vizcaya, D., Volpe, S., Wen, H., Williams, A. E., Yimer, B. B., Zhang, L., Zhuk, O., Prieto-Alhambra, D. & Ryan, P., 2020, In: Nature Communications. 11, 1, 11 p., 5009.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    Dynamic and explainable machine learning prediction of mortality in patients in the intensive care unit: a retrospective study of high-frequency data in electronic patient records

    Thorsen-Meyer, H., Nielsen, Annelaura Bach, Nielsen, A. P., Kaas-Hansen, Benjamin Skov, Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Dybdahl, L., Spangsege, L., Hulsen, P., Belling, K., Brunak, Søren & Perner, Anders, 2020, In: The Lancet Digital Health. 2, 4, p. e179–91 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  42. Published

    Heterogeneity of treatment effect of prophylactic pantoprazole in adult ICU patients: a post hoc analysis of the SUP-ICU trial

    Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, van der Horst, I. C. C., Lange, Theis, Wetterslev, J., Perner, Anders & Møller, Morten Hylander, 2020, In: Intensive Care Medicine. 46, p. 717–726 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  43. Published

    Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study

    Lane, J. C. E., Weaver, J., Kostka, K., Duarte-Salles, T., Abrahao, M. T. F., Alghoul, H., Alser, O., Alshammari, T. M., Biedermann, P., Banda, J. M., Burn, E., Casajust, P., Conover, M. M., Culhane, A. C., Davydov, A., DuVall, S. L., Dymshyts, D., Fernandez-Bertolin, S., Fišter, K., Hardin, J. & 31 others, Hester, L., Hripcsak, G., Kaas-Hansen, Benjamin Skov, Kent, S., Khosla, S., Kolovos, S., Lambert, C. G., van der Lei, J., Lynch, K. E., Makadia, R., Margulis, A. V., Matheny, M. E., Mehta, P., Morales, D. R., Morgan-Stewart, H., Mosseveld, M., Newby, D., Nyberg, F., Ostropolets, A., Park, R. W., Prats-Uribe, A., Rao, G. A., Reich, C., Reps, J., Rijnbeek, P., Sathappan, S. M. K., Schuemie, M., Seager, S., Sena, A. G., Shoaibi, A. & OHDSI-COVID-19 consortium, O. C., 2020, In: The Lancet Rheumatology. 2, 11, p. e698-e711 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  44. 2019
  45. Published

    Different Original and Biosimilar TNF Inhibitors Similarly Reduce Joint Destruction in Rheumatoid Arthritis-A Network Meta-Analysis of 36 Randomized Controlled Trials

    Graudal, N., Kaas-Hansen, Benjamin Skov, Guski, L., Hubeck-Graudal, T., Welton, N. J. & Jürgens, Gesche, 2019, In: International Journal of Molecular Sciences. 20, 18, 19 p., 4350.

    Research output: Contribution to journalReviewpeer-review

  46. Published

    Heterogeneity of treatment effect of stress ulcer prophylaxis in ICU patients: A secondary analysis protocol

    Granholm, A., Marker, S., Krag, M., Zampieri, F. G., Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, van der Horst, I. C. C., Lange, Theis, Wetterslev, J., Perner, Anders & Møller, Morten Hylander, 2019, In: Acta Anaesthesiologica Scandinavica. 63, 9, p. 1251-1256 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  47. 2016
  48. Published

    Severe Violence in Eastern Jutland 2003-2014

    Kaas-Hansen, Benjamin Skov & Hansen, O. I., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. 2015
  50. Published

    Severe violence in Eastern Jutland 2003-2014: a pilot study [v1; not peer reviewed]: A pilot study [v1; not peer reviewed]

    Kaas-Hansen, Benjamin Skov, 7 Nov 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  51. 2013
  52. Beyond access to medicines: Eliciting high-income country support for a new global health research and development paradigm

    Regmi, S., Kaas-Hansen, Benjamin Skov & Iversen, J. H., 2013, In: Journal of Global Health. 3, 2, 6 p., 020303.

    Research output: Contribution to journalReviewpeer-review

ID: 185059892