Axel Kornerup Hansen

Axel Kornerup Hansen

Professor

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    ORCID: 0000-0003-1575-2507

    Publication year:
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    1 - 50 out of 334Page size: 50
    1. 2024
    2. Published

      High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs

      Lützhøft, Ditte Olsen, Bækgård, Cecilie, Wimborne, E., Straarup, E. M., Pedersen, K. M., Swann, J. R., Pedersen, H. D., Kristensen, K., Morgills, L., Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Bracken, M. K., Cirera, Susanna & Christoffersen, B. Ø., 2024, In: PLoS ONE. 19, 3, 27 p., e0298602.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Induction of CD8+ immune memory and enhanced inflammation in a skin inflammation model through pre-immunization with inactivated pathogens

      Falkenberg, C., Bartholdy, C., Koch, J., Toft, M., Skov, Søren, Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2024, In: Clinical and Translational Science. 17, 1, 14 p., e13697.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2023
    5. Published

      CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice

      Rasmussen, Torben Sølbeck, Koefoed, A. K., Deng, Ling, Muhammed, Musemma Kedir, Rousseau, G. M., Kot, Witold, Sprotte, S., Neve, H., Franz, C. M. A. P., Hansen, Axel Kornerup, Vogensen, Finn Kvist, Moineau, S. & Nielsen, Dennis Sandris, 2023, In: ISME Journal. 17, p. 432–442

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Fecal virome transfer improves proliferation of commensal gut Akkermansia muciniphila and unexpectedly enhances the fertility rate in laboratory mice

      Rasmussen, Torben Sølbeck, Mentzel, Caroline M. Junker, Danielsen, M. R., Jakobsen, Rasmus Riemer, Zachariassen, L. S. F., Castro Mejia, J. L., Brunse, Anders, Hansen, Lars Hestbjerg, Hansen, Camilla Hartmann Friis, Hansen, Axel Kornerup & Nielsen, Dennis Sandris, 2023, In: Gut Microbes. 15, 1, 21 p., 2208504.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Imiquimod induces skin inflammation in humanized BRGSF mice with limited human immune cell activity

      Christensen, P. K. F., Hansen, Axel Kornerup, Skov, Søren, Martel, B. C., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: PLoS ONE. 18, e0281005.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition

      Stensballe, A., Bennike, T. B., Ravn-Haren, G., Mortensen, A., Aboo, C., Knudsen, L. A., Rühlemann, M. C., Birkelund, S., Bang, C., Franke, A., Vogel, U., Hansen, Axel Kornerup & Andersen, V., 2023, In: Frontiers in Medicine. 10, 1200317.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Inulin Supplementation Modulates the Hepatic Transcriptome, Metabolome, and Ferritin Content in Ovariectomized Rats

      Zhao, X., He, W., Jakobsen, L. M. A., Zachariassen, L. F., Hansen, Axel Kornerup, Rasmussen, M. K. & Bertram, H. C., 2023, In: Molecular Nutrition and Food Research. 67, 23, 10 p., 2300372.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

      Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.

      Research output: Contribution to journal › Review › Research › peer-review

    11. Published

      Maternal antibiotic exposure increases total islet number and volume in the neonatal pancreas and reduces HbA1c and insulitis in adult female non-obese diabetic mice

      Hansen, Camilla Hartmann Friis, Haupt-Jorgensen, M., Buschard, K., Pakkenberg, B., Krych, Lukasz & Hansen, Axel Kornerup, 2023, In: Clinical and Translational Discovery. 3, 2, 13 p., e188.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic Syndrome

      von Münchow, Alexandra, Torp Yttergren, S., Jakobsen, Rasmus Riemer, Luthersson, N., Hansen, Axel Kornerup & Lindenberg, F., 2023, In: Frontiers in Microbiomes. 2, p. 1194705 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Sustaining the T-cell activity in xenografted psoriasis skin

      Christensen, P. K. F., Hansen, Axel Kornerup, Skov, Søren, Engkilde, K., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: PLoS ONE. 18, e0278390.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      The impact of bacterial exposure in early life on lung surfactant gene expression, function and respiratory rate in germ-free mice

      Barfod, Kenneth Klingenberg, Lui, J. C., Hansen, Signe Schmidt Kjølner, Sengupta, S., Zachariassen, L. S. F., Hansen, Axel Kornerup & Sørli, J. B., 2023, In: Frontiers in Microbiomes. 2, 12 p., 1085508.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

      Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. 2022
    17. Published

      Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

      Bondarenko, V., Løkke, Cecillie Reynolds, Dobrowolski, P., Mentzel, Caroline M. Junker, Castro-Mejia, J. L., Hansen, Camilla Hartmann Friis, Sørensen, Dorte Bratbo, Nielsen, Dennis Sandris, Krych, Lukasz & Hansen, Axel Kornerup, 2022, In: Scientific Reports. 12, 12 p., 13767.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Dual nuclear magnetic resonance for probing intrinsic bone structure and a potential gut–bone axis in ovariectomized rats

      He, W., Jakobsen, L. M. A., Zachariassen, L. F., Hansen, Axel Kornerup, Andersen, H. J. & Bertram, H. C., 2022, In: Magnetic Resonance in Chemistry. 60, 7, p. 651-658

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Dyreforsøg

      Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2022, Veterinær Retsmedicin. Agger, J. F. G., Houe, H. & Otten, N. D. (eds.). 1 ed. Frederiksberg, Denmark: Biofolia

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

    20. Published

      Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

      Kihl, Pernille, Krych, Lukasz, Deng, Ling, Hansen, Lars Hestbjerg, Buschard, K., Skov, Søren, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: Plos One. 17, 4, 21 p., e0266719.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Effects of Calcium Source, Inulin, and Lactose on Gut-Bone Associations in an Ovarierectomized Rat Model

      He, W., Xie, Zhuqing, Thøgersen, R., Rasmussen, M. K., Zachariassen, L. F., Jørgensen, Niklas Rye, Nørgaard, J. V., Andersen, H. J., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Bertram, H. C., 2022, In: Molecular Nutrition and Food Research. 66, 8, 12 p., 2100883.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Gluten-free diet reduces autoimmune diabetes mellitus in mice across multiple generations in a microbiota-independent manner

      Hansen, Camilla Hartmann Friis, Larsen, C. S., Zachariassen, L. F., Mentzel, Caroline M. Junker, Laigaard, A., Krych, Lukasz, Nielsen, Dennis Sandris, Gobbi, Alex, Haupt-Jorgensen, M., Buschard, K. & Hansen, Axel Kornerup, 2022, In: Journal of Autoimmunity. 127, 102795.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function

      Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Ind- og udførsel af levende dyr

      Nielsen, Søren Saxmose & Hansen, Axel Kornerup, 2022, Veterinær Retsmedicin. Agger, J. F. G., Houe, H. & Otten, N. D. (eds.). 1 ed. Frederiksberg, Denmark: Biofolia

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

    25. Published

      Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

      Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Oligosaccharide equine feed supplement, Immulix, has minor impact on vaccine responses in mice

      Henriksen, Ida Wang , Mejia, J. L. C., Mentzel, Caroline M. Junker, Lindenberg, F. & Hansen, Axel Kornerup, 2022, In: Scientific Reports. 12, 582.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Pre-immunization with inactivated pathogens recapitulates adult human immune traits in laboratory mice

      Falkenberg, C., Toft, M. F., Skov, Søren & Hansen, Axel Kornerup, 2022, In: Laboratory Animals. 56, S1, p. 25-25 S2A5.3.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    28. Published

      Yogurt Benefits Bone Mineralization in Ovariectomized Rats with Concomitant Modulation of the Gut Microbiome

      He, W., Xie, Zhuqing, Wittig, N. K., Zachariassen, L. F., Andersen, A., Andersen, H. J., Birkedal, H., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Bertram, H. C., 2022, In: Molecular Nutrition and Food Research. 66, 20, 10 p., 2200174.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. 2021
    30. Published

      Administration of bovine milk oligosaccharide to weaning gnotobiotic mice inoculated with a simplified infant type microbiota

      Jakobsen, L. M. A., Sundekilde, U. K., Andersen, H. J., Kot, Witold, Mejia, J. L. C., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Bertram, H. C., 2021, In: Microorganisms. 9, 5, 1003.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

      Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Delayed Gut Colonization Shapes Future Allergic Responses in a Murine Model of Atopic Dermatitis

      Arildsen, A. W., Zachariassen, L. F., Krych, Lukasz, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2021, In: Frontiers in Immunology. 12, 650621.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Effects of delivery mode on behavior in mouse offspring

      Zachariassen, L. F., Sørensen, Dorte Bratbo, Krych, Lukasz, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2021, In: Physiology and Behavior. 230, 113285.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Inter-vendor variance of enteric eukaryotic DNA viruses in specific pathogen free C57BL/6N mice

      Rasmussen, Torben Sølbeck, Jakobsen, Rasmus Riemer, Castro-Mejía, J. L., Kot, Witold, Thomsen, Allan Randrup, Vogensen, Finn Kvist, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Research in Veterinary Science. 136, p. 1-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Partial substitution of meat with insect (Alphitobius diaperinus) in a carnivore diet changes the gut microbiome and metabolome of healthy rats

      Lanng, S. K., Zhang, Yichang, Christensen, K. R., Hansen, Axel Kornerup, Nielsen, Dennis Sandris, Kot, Witold & Bertram, H. C., 2021, In: Foods. 10, 8, 14 p., 1814.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Systems-wide effects of short-term feed deprivation in obese mice

      Andersen, D., Roager, Henrik Munch, Zhang, L., Moll, J. M., Frandsen, H. L., Danneskiold-Samsøe, Niels Banhos, Hansen, Axel Kornerup, Kristiansen, Karsten, Licht, T. R. & Brix, Susanne, 2021, In: Scientific Reports. 11, 11 p., 5716.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The microbiome and rodent models of immune mediated diseases

      Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2021, In: Mammalian Genome. 32, p. 251–262

      Research output: Contribution to journal › Review › Research › peer-review

    38. 2020
    39. Published

      In vivo fluorescence molecular tomography of induced haemarthrosis in haemophilic mice: link between bleeding characteristics and development of bone pathology

      Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 14 Apr 2020, In: BMC Musculoskeletal Disorders. 21, 1, 10 p., 241.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      A Humanized Diet Profile May Facilitate Colonization and Immune Stimulation in Human Microbiota-Colonized Mice

      Moreno-Indias, I., Lundberg, R., Krych, Lukasz, Metzdorff, S. B., Kot, Witold, Sørensen, Dorte Bratbo, Nielsen, Dennis Sandris, Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2020, In: Frontiers in Microbiology. 11, 15 p., 1336.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Betamethasone Treatment for Atopic Dermatitis in Gut Microbiota Transplanted Mice

      Debes, Karina Poulsdóttir, Evdina, N. A., Laigaard, A., Larsen, J. M., Zachariassen, L. F., Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2020, In: Comparative Medicine. 70, 1, p. 6-15 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      C57BL/6J substrain differences in response to high-fat diet intervention

      Siersbæk, M. S., Ditzel, N., Hejbøl, E. K., Præstholm, S. M., Markussen, L. K., Avolio, F., Li, L., Lehtonen, L., Hansen, Axel Kornerup, Schrøder, H. D., Krych, Lukasz, Mandrup, S., Langhorn, L., Bollen, Peter & Grøntved, L., 2020, In: Scientific Reports. 10, 1, 15 p., 14052.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Dietary prebiotics promote intestinal Prevotella in association with a low-responding phenotype in a murine oxazolone-induced model of atopic dermatitis

      Laigaard, A., Krych, Lukasz, Zachariassen, L. F., Ellegaard-Jensen, L., Nielsen, Dennis Sandris, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: Scientific Reports. 10, 1, 11 p., 21204.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model

      Rasmussen, Torben Sølbeck, Mentzel, Caroline M. Junker, Kot, Witold, Castro-Mejiá, J. L., Zuffa, S., Swann, J. R., Hansen, Lars Hestbjerg, Vogensen, Finn Kvist, Hansen, Axel Kornerup & Nielsen, Dennis Sandris, 2020, In: Gut. 69, 12, p. 2122-2130 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Human microbiota-transplanted C57BL/6 mice and offspring display reduced establishment of key bacteria and reduced immune stimulation compared to mouse microbiota-transplantation

      Lundberg, R., Toft, M. F., Metzdorff, S. B., Hansen, Camilla Hartmann Friis, Licht, T. R., Bahl, M. I. & Hansen, Axel Kornerup, 2020, In: Scientific Reports. 10, 16 p., 7805.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Initial joint bleed volume in a delayed on-demand treatment setup correlates with subsequent synovial changes in hemophilic mice

      Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2020, In: Animal models and experimental medicine. 3, 2, p. 160-168 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Inulin and milk mineral fortification of a pork sausage exhibits distinct effects on the microbiome and biochemical activity in the gut of healthy rats

      Thøgersen, R., Castro-Mejía, J. L., Sundekilde, U. K., Hansen, Lars Hestbjerg, Gray, N., Kuhnle, G., Jørgensen, Niklas Rye, Hansen, Axel Kornerup, Nielsen, Dennis Sandris & Bertram, H. C., 2020, In: Food Chemistry. 331, 10 p., 127291.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Inulin-fortification of a processed meat product attenuates formation of nitroso compounds in the gut of healthy rats

      Thøgersen, R., Gray, N., Kuhnle, G., Van Hecke, T., De Smet, S., Young, J. F., Sundekilde, U. K., Hansen, Axel Kornerup & Bertram, H. C., 2020, In: Food Chemistry. 302, 7 p., 125339.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Proteoglycan synthesis rate as a novel method to measure blood-induced cartilage degeneration in non-haemophilic and haemophilic rats

      Pulles, A. E., Vøls, Kåre Kryger, Christensen, K. R., Coeleveld, K., Hansen, Axel Kornerup, van Vulpen, L. F. D., Petersen, M., Mastbergen, S. C., Roepstorff, K., Schutgens, R. E. G., Kjelgaard-Hansen, M. & Lafeber, F. P. J. G., 2020, In: Haemophilia. 26, 3, p. e88-e96

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

      Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Translational potential of metabolomics on animal models of inflammatory bowel disease: a systematic critical review

      Knudsen, L. A., Desdorf, R., Möller, S., Sørensen, S. B., Hansen, Axel Kornerup & Andersen, V., 2020, In: International Journal of Molecular Sciences . 21, 11, 28 p., 3856.

      Research output: Contribution to journal › Review › Research › peer-review

    52. 2019
    53. Published

      Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies

      Hu, H., Kofoed, Christian, Li, M., Gonçalves, J. P. L., Hansen, J., Wolfram, M., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis, Diness, Frederik, Schoffelen, S. & Meldal, Morten Peter, 27 Feb 2019, In: ACS Central Science. 5, 2, p. 259-269 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Bacterial species to be considered in quality assurance of mice and rats

      Hansen, Axel Kornerup, Nielsen, Dennis Sandris, Krych, Lukasz & Hansen, Camilla Hartmann Friis, 2019, In: Laboratory Animals. 53, 3, p. 281-291

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy

      Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2019, In: Haemophilia. 25, 2, p. 324-333 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Cesarean Section Induces Microbiota-Regulated Immune Disturbances in C57BL/6 Mice

      Zachariassen, L. F., Krych, Lukasz, Rasmussen, S. H., Nielsen, Dennis Sandris, Kot, W., Holm, T. L., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2019, In: Journal of Immunology. 202, 1, p. 142-150

      Research output: Contribution to journal › Journal article › Research › peer-review

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