Arne Schousboe
Professor, emeritus
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- 2023
- Accepted/In press
A tribute to Leif Hertz: The historical context of his pioneering studies of the roles of astrocytes in brain energy metabolism, neurotransmission, cognitive functions, and pharmacology identifies important, unresolved topics for future studies
Dienel, G. A., Schousboe, Arne, McKenna, M. C. & Rothman, D. L., 2023, (Accepted/In press) In: Journal of Neurochemistry.Research output: Contribution to journal › Review › peer-review
- Published
Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling
Andersen, Jens Velde, Schousboe, Arne & Wellendorph, Petrine, 2023, In: Essays in Biochemistry. 67, 1, p. 77-91Research output: Contribution to journal › Journal article › peer-review
- Accepted/In press
Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex
Andersen, Jens Velde, Westi, Emil Winther, Griem-Krey, Nane, Skotte, Niels Henning, Schousboe, Arne, Aldana, Blanca & Wellendorph, Petrine, 2023, (Accepted/In press) In: Journal of Neurochemistry.Research output: Contribution to journal › Journal article › peer-review
- Published
Glial Glutamine Homeostasis in Health and Disease
Andersen, J. V. & Schousboe, Arne, 2023, In: Neurochemical Research. 48, p. 1100–1128Research output: Contribution to journal › Review › peer-review
- Published
Glutamate Neurotoxicity Related to Energy Failure
Schousboe, Arne, 2023, Handbook of Neurotoxicity. 2 ed. Springer, p. 803-815 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Milestone Review: Metabolic dynamics of glutamate and GABA mediated neurotransmission — The essential roles of astrocytes
Andersen, Jens Velde & Schousboe, Arne, 2023, In: Journal of Neurochemistry. 166, 2, p. 109-137Research output: Contribution to journal › Review › peer-review
- Published
The history of Danish neuroscience
Paulson, Olaf B., Schousboe, Arne & Hultborn, Hans, 2023, In: European Journal of Neuroscience. 58, 4, p. 2893-2960Research output: Contribution to journal › Editorial › peer-review
- 2022
- Published
Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: Integration of the glutamate/GABA-glutamine cycle
Andersen, Jens Velde, Schousboe, Arne & Verkhratsky, A., 2022, In: Progress in Neurobiology. 217, 24 p., 102331.Research output: Contribution to journal › Review › peer-review
- Published
Low cerebral energy metabolism in hepatic encephalopathy reflects low neuronal energy demand. Role of ammonia-induced increased GABAergic tone
Sorensen, M., Walls, Anne Byriel, Dam, G., Bak, Lasse Kristoffer, Andersen, Jens Velde, Ott, P., Vilstrup, H. & Schousboe, Arne, 2022, In: Analytical Biochemistry. 654, 4 p., 114766.Research output: Contribution to journal › Journal article › peer-review
- 2021
- Published
Amino acids: Glutamate dehydrogenase: An anaplerotic enzyme in neurons and an energy producing enzyme in astrocytes
Schousboe, Arne & Aldana, Blanca, 29 Jul 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 51-55 5 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease
Andersen, Jens Velde, Christensen, S. K., Westi, Emil Winther, Diaz-delcastillo, M., Tanila, H., Schousboe, Arne, Aldana, Blanca & Waagepetersen, Helle S., 2021, In: Neurobiology of Disease. 148, 13 p., 105198.Research output: Contribution to journal › Journal article › peer-review
- Published
Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease
Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia
Voss, C. M., Arildsen, L., Nissen, J. D., Waagepetersen, Helle S., Schousboe, Arne, Maechler, P., Ott, P., Vilstrup, H. & Walls, Anne Byriel, 2021, In: Frontiers in Neuroscience. 15, 18 p., 646291.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration
Andersen, Jens Velde, Markussen, K. H., Jakobsen, Emil, Schousboe, Arne, Waagepetersen, Helle S., Rosenberg, P. A. & Aldana, Blanca, 2021, In: Neuropharmacology. 196, 14 p., 108719.Research output: Contribution to journal › Review › peer-review
- Published
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease
Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .Research output: Contribution to journal › Journal article › peer-review
- Published
Preface for the Vladimir Parpura Honorary Issue of Neurochemical Research
Verkhratsky, A., Schousboe, Arne & Zorec, R., 2021, In: Neurochemical Research. 46, 10, p. 2507-2511Research output: Contribution to journal › Editorial
- Published
Two Metabolic Fuels, Glucose and Lactate, Differentially Modulate Exocytotic Glutamate Release from Cultured Astrocytes
Montana, V., Flint, D., Waagepetersen, Helle S., Schousboe, Arne & Parpura, V., 2021, In: Neurochemical Research. 46, p. 2551–2579Research output: Contribution to journal › Journal article › peer-review
- 2020
- Published
Astrocytic Metabolism Focusing on Glutamate Homeostasis: A Short Review Dedicated to Vittorio Gallo
Schousboe, Arne, 2020, In: Neurochemical Research. 45, 3, p. 522-525Research output: Contribution to journal › Journal article › peer-review
- Published
Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex
Andersen, Jens Velde, Jakobsen, Emil, Westi, Emil Winther, Lie, M. E. K., Voss, C. M., Aldana, Blanca, Schousboe, Arne, Wellendorph, Petrine, Bak, Lasse Kristoffer, Pinborg, Lars Hageman & Waagepetersen, Helle S., 2020, In: Glia. 68, 12, p. 2601-2612Research output: Contribution to journal › Journal article › peer-review
- Published
Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects
Lie, M. E. K., Kickinger, S., Skovgaard-Petersen, J., Ecker, G. F., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Wellendorph, Petrine, 2020, In: Neurochemical Research. 45, p. 1551–1565Research output: Contribution to journal › Journal article › peer-review
- Published
Preface for the Vittorio Gallo Honorary Issue of Neurochemical Research
Schousboe, Arne, 2020, In: Neurochemical Research. 45, 3, p. 519-521Research output: Contribution to journal › Editorial › peer-review
- 2019
- Published
Astrocytic pyruvate carboxylation: Status after 35 years
Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 1 Jan 2019, In: Journal of Neuroscience Research. 97, p. 890-896Research output: Contribution to journal › Review › peer-review
- Published
Metabolic signaling in the brain and the role of astrocytes in control of glutamate and GABA neurotransmission
Schousboe, Arne, 2019, In: Neuroscience Letters. 689, p. 11-13 3 p.Research output: Contribution to journal › Review › peer-review
- Published
Preface: Special issue on neurotransmitter transporters
Chaudhry, F. A., Loland, Claus Juul, Ortega, A. & Schousboe, Arne, 2019, In: Neuropharmacology. 161, 1 p., 107859.Research output: Contribution to journal › Editorial › peer-review
- Published
Special Issue in Honor of Dr. Elias K. Michaelis
Choi, I. & Schousboe, Arne, 2019, In: Neurochemical Research. 44, 1, p. 1-4Research output: Contribution to journal › Journal article › peer-review
- Published
State-Dependent Changes in Brain Glycogen Metabolism
DiNuzzo, M., Walls, Anne Byriel, Öz, G., Seaquist, E. R., Waagepetersen, Helle S., Bak, Lasse Kristoffer, Nedergaard, Maiken & Schousboe, Arne, 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (eds.). Springer, p. 269-309 41 p. (Advances in Neurobiology, Vol. 23).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Structural and molecular aspects of betaine-GABA transporter 1 (BGT1) and its relation to brain function
Kickinger, S., Hellsberg, E., Frølund, Bente, Schousboe, Arne, Ecker, G. F. & Wellendorph, Petrine, 2019, In: Neuropharmacology. 161, 14 p., 107644.Research output: Contribution to journal › Review › peer-review
- Published
The 13th International Conference on Brain Energy Metabolism: "How Metabolism Dictates Neurotransmission, Function and Behavior"
Barros, L. F., Schousboe, Arne & McKenna, M. C., 2019, In: Journal of Neuroscience Research. 97, 8, p. 849-853 5 p.Research output: Contribution to journal › Journal article
- 2018
- Published
Astrocytic glycogen metabolism in the healthy and diseased brain
Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne & Waagepetersen, Helle S., 11 May 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7108-7116 9 p.Research output: Contribution to journal › Review › peer-review
- 2017
- Published
Misconceptions regarding basic thermodynamics and enzyme kinetics have led to erroneous conclusions regarding the metabolic importance of lactate dehydrogenase isoenzyme expression
Bak, Lasse Kristoffer & Schousboe, Arne, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2098-2102 5 p.Research output: Contribution to journal › Review › peer-review
- Published
The 12th International Conference on Brain Energy Metabolism (ICBEM): "Energy Metabolism and Neuron-Glia Interactions in Brain: From Molecular Mechanisms to Novel Therapeutic Approaches"
Yu, A. C. H., Schousboe, Arne & McKenna, M. C., Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2095-2097 3 p.Research output: Contribution to journal › Journal article
- Published
The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells
Aldana, Blanca, Waagepetersen, Helle S., Schousboe, Arne, White, H. S., Bulaj, G. & Walls, Anne Byriel, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2286-2296 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1)
Jørgensen, L., Al-Khawaja, A., Kickinger, S., Vogensen, S. B., Skovgaard-Petersen, J., Rosenthal, E., Borkar, N., Löffler, R., Madsen, K. K., Bräuner, Hans, Schousboe, Arne, Ecker, G. F., Wellendorph, Petrine & Clausen, Rasmus Prætorius, 9 Oct 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8834-8846Research output: Contribution to journal › Journal article › peer-review
- Published
Glycogen Shunt Activity and Glycolytic Supercompensation in Astrocytes May Be Distinctly Mediated via the Muscle Form of Glycogen Phosphorylase
Jakobsen, Emil, Bak, Lasse Kristoffer, Walls, Anne Byriel, Christiansen, Ann-Kathrin Lindahl, Schousboe, Arne & Waagepetersen, Helle S., Sep 2017, In: Neurochemical Research. 42, 9, p. 2490-2494 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Delineation of the Role of Astroglial GABA Transporters in Seizure Control
Schousboe, Arne & Madsen, K. K., Jul 2017, In: Neurochemical Research. 42, 7, p. 2019-2023Research output: Contribution to journal › Journal article › peer-review
- Published
Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS
Westergaard, N., Waagepetersen, Helle S., Belhage, B. & Schousboe, Arne, Jun 2017, In: Neurochemical Research. 42, 6, p. 1583-1588 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A Tribute to Mary C. McKenna: Glutamate as Energy Substrate and Neurotransmitter-Functional Interaction Between Neurons and Astrocytes
Schousboe, Arne, Jan 2017, In: Neurochemical Research. 42, 1, p. 4-9 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs
Schousboe, Arne, Wellendorph, Petrine, Frølund, Bente, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 283-296 14 p. (Advances in Neurobiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes
Nissen, J. D., Lykke, K., Bryk, J., Stridh, M. H., Zaganas, I., Jensen, Dorte Skytt, Schousboe, Arne, Bak, Lasse Kristoffer, Enard, W., Pääbo, S. & Waagepetersen, Helle S., 2017, In: Glia. 65, 3, p. 474–488Research output: Contribution to journal › Journal article › peer-review
- Published
Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke
Lie, M. E. K., Al-Khawaja, A., Damgaard, M., Haugaard, A. S., Schousboe, Arne, Clarkson, A. N. & Wellendorph, Petrine, 2017, Advances in Neurobiology. Vol. 16. p. 137-167 31 p. (Advances in Neurobiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology
Parpura, V., Fisher, E. S., Lechleiter, J. D., Schousboe, Arne, Waagepetersen, Helle S., Brunet, S., Baltan, S. & Verkhratsky, A., 2017, In: Neurochemical Research. 42, 1, p. 19-34 16 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-(13)C]Glucose and [1,2-(13)C]Acetate as Substrates
McNair, Laura M., Kornfelt, R., Walls, Anne Byriel, Andersen, Jens Velde, Aldana, B. I., Nissen, J. D., Schousboe, Arne & Waagepetersen, Helle S., 2017, In: Neurochemical Research. 42, 3, p. 810-826 17 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Preface for the Mary C. McKenna Honorary Issue of Neurochemical Research
Schousboe, Arne, 2017, In: Neurochemical Research. 42, 1, 1-3.Research output: Contribution to journal › Editorial
- Published
Preface for the Ursula Sonnewald Honorary Issue of Neurochemical Research
Schousboe, Arne, 2017, In: Neurochemical Research. 42, 6, p. 1581-1582 2 p.Research output: Contribution to journal › Editorial
- Published
Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine synthesis
Andersen, Jens Velde, McNair, Laura M., Schousboe, Arne & Waagepetersen, Helle S., 2017, In: Journal of Neuroscience Research. 95, 11, p. 2207-2216Research output: Contribution to journal › Journal article › peer-review
- Published
gamma-Aminobutyric Acid and Glycine Neurotransmitter Transporters
Wellendorph, Petrine, Jacobsen, Julie, Skovgaard-Petersen, J., Jurik, A., Vogensen, S. B., Ecker, G., Schousboe, Arne, Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 2017, Transporters As Drug Targets.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2016
- Published
Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases
McKenna, M. C., Stridh, M. H., McNair, Laura M., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 15 Sep 2016, In: Journal of Neuroscience Research. 94, 12, p. 1561-1571 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission
Walls, Anne Byriel, Flynn, S. P., West, P. J., Müller, M. S., Bak, Lasse Kristoffer, Bulaj, G., Schousboe, Arne & White, H. S., Mar 2016, In: Epilepsy Research. 121, p. 55-63 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism
Jayakumar, A. R., Bak, Lasse Kristoffer, Rama Rao, K. V., Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Feb 2016, In: Neurochemical Research. 41, 1, p. 307-15 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
40 year anniversary issue of neurochemical research
Schousboe, Arne, 2016, In: Neurochemical Research. 41, 1-2, p. 1-2 2 p.Research output: Contribution to journal › Editorial
- Published
Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood
Brekke, E., Morken, T. S., Walls, Anne Byriel, Waagepetersen, Helle S., Schousboe, Arne & Sonnewald, U., 2016, The Glutamate/ GABA- Glutamine Cycle : Amino Acid Neurotransmitter Homeostasis. Springer, Vol. 13. p. 43-58 16 p. (Advances in Neurobiology, Vol. 13).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Introduction to the Glutamate-Glutamine Cycle
Sonnewald, U. & Schousboe, Arne, 2016, 7 p. (Advances in Neurobiology).Research output: Book/Report › Anthology › peer-review
- Published
The Glutamine Transporters and Their Role in the Glutamate/GABA-Glutamine Cycle
Leke, R. & Schousboe, Arne, 2016, 35 p. (Advances in Neurobiology).Research output: Book/Report › Anthology › peer-review
- 2015
- Published
Glutamate neurotransmission is affected in prenatally stressed offspring
Adrover, E., Pallarés, M. E., Baier, C. J., Monteleone, M. C., Giuliani, F. A., Waagepetersen, Helle S., Brocco, M. A., Cabrera, R., Sonnewald, U., Schousboe, Arne & Antonelli, M. C., Sep 2015, In: Neurochemistry International. 88, p. 73-87 15 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Two isoforms of glycogen phosphorylase activated by the same signaling trains: how and why?
Bak, Lasse Kristoffer, Mueller, M. S., Fox, R., Pedersen, Sofie E., Walls, Anne Byriel, Christiansen, Ann-Kathrin Lindahl, Jakobsen, E., Schousboe, Arne & Waagepetersen, Helle S., Aug 2015, In: Journal of Neurochemistry. 134, suppl. 1, p. 56-56 1 p., S26-01.Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Glucose replaces glutamate as energy substrate to fuel glutamate uptake in glutamate dehydrogenase-deficient astrocytes
Pajęcka, K., Nissen, J. D., Stridh, M. H., Jensen, Dorte Skytt, Schousboe, Arne & Waagepetersen, Helle S., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 1093-100 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The 11th International Conference on Brain Energy Metabolism "how energy metabolism shapes brain function". Preface: Preface
Waagepetersen, Helle S., Schousboe, Arne & McKenna, M. C., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 985-6 2 p.Research output: Contribution to journal › Journal article
- Published
Structure activity relationship of selective GABA uptake inhibitors
Vogensen, S. B., Jørgensen, L., Madsen, K. K., Jurik, A., Borkar, N., Rosatelli, E., Nielsen, Birgitte, Ecker, G. F., Schousboe, Arne & Clausen, Rasmus Prætorius, 15 May 2015, In: Bioorganic & Medicinal Chemistry. 23, 10, p. 2480-2488 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
AMPK Activation Affects Glutamate Metabolism in Astrocytes
Voss, C. M., Pajęcka, K., Stridh, M. H., Nissen, J. D., Schousboe, Arne & Waagepetersen, Helle S., 7 Apr 2015, In: Neurochemical Research. 40, 12, p. 2431-2442 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Brain glycogen: emergency fuel and dynamic function in neurotransmission
Walls, Anne Byriel & Schousboe, Arne, Feb 2015, In: Metabolic Brain Disease. 30, 1, p. 249-249 1 p.Research output: Contribution to journal › Journal article
- Published
The Glutamine-Glutamate/GABA Cycle: Function, Regional Differences in Glutamate and GABA Production and Effects of Interference with GABA Metabolism
Walls, Anne Byriel, Waagepetersen, Helle S., Bak, Lasse Kristoffer, Schousboe, Arne & Sonnewald, U., Feb 2015, In: Neurochemical Research. 40, 2, p. 402-9 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The Subcellular Localization of GABA Transporters and Its Implication for Seizure Management
Madsen, K. K., Hansen, Gert Helge, Danielsen, E. M. & Schousboe, Arne, Feb 2015, In: Neurochemical Research. 40, 2, p. 410-419 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamine and ammonia in hepatic encephalopathy
Dadsetan, S., Waagepetersen, Helle S., Schousboe, Arne & Bak, Lasse Kristoffer, 1 Jan 2015, Glutamine in Clinical Nutrition. Springer New York LLC, p. 219-227 9 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Expression of glutamine transporter isoforms in cerebral cortex of rats with chronic hepatic encephalopathy
Leke, R., Escobar, T. D. C., Rama Rao, K. V., Silveira, T. R., Norenberg, M. D. & Schousboe, Arne, 2015, In: Neurochemistry International. 88, p. 32-37 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate and ATP: The crossroads of signaling and metabolism in the brain.
Verkhratsky, A., Schousboe, Arne & Parpura, V., 2015, Advances in Neurobiology. Schousboe, A. (ed.). USA: Springer Publishing Company, Vol. 11. p. 1-12 12 p. (Advances in Neurobiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- 2014
- Published
Introduction to special issue in honor of Professor Povl Krogsgaard-Larsen
Bräuner, Hans & Schousboe, Arne, Oct 2014, In: Neurochemical Research. 39, 10, p. 1845-6 2 p.Research output: Contribution to journal › Journal article
- Published
A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo
Walls, Anne Byriel, Eyjolfsson, E. M., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., Aug 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 8, p. 1340-6 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis
Müller, M. S., Fox, R., Schousboe, Arne, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, Apr 2014, In: Glia. 62, 4, p. 526-34 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro
Schousboe, Arne, Waagepetersen, Helle S., Leke, R. & Bak, Lasse Kristoffer, 1 Mar 2014, In: Metabolic Brain Disease. 29, 4, p. 913-917 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats
Fries, A. W., Dadsetan, S., Keiding, S., Bak, Lasse Kristoffer, Schousboe, Arne, Waagepetersen, Helle S., Simonsen, M., Ott, P., Vilstrup, H. & Sørensen, M., Mar 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 3, p. 460-6 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Metabolic mapping of astrocytes and neurons in culture using stable isotopes and gas chromatography-mass spectrometry (GC-MS)
Walls, Anne Byriel, Bak, Lasse Kristoffer, Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Jan 2014, In: Neuromethods. 90, p. 73-105 33 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Expression of glutamate decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy
Leke, R., Silveira, T., Escobar, T. & Schousboe, Arne, 2014, In: Neurochemical Research. 39, 3, p. 605-611 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization
Pajęcka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, Lasse Kristoffer, Schousboe, Arne, Plaitakis, A. & Waagepetersen, Helle S., 2014, In: Neurochemical Research. 39, 3, p. 487-99 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate metabolism in the brain focusing on astrocytes
Schousboe, Arne, Scafidi, S., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & McKenna, M. C., 2014, In: Advances in Neurobiology. 11, p. 13-30 18 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans
Iversen, P., Mouridsen, K., Hansen, M. B., Jensen, S. B., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Ott, P., Vilstrup, H., Keiding, S. & Gjedde, Albert, 2014, In: Frontiers in Neuroscience. 8, p. 353Research output: Contribution to journal › Journal article › peer-review
- Published
The GABA Synapse as a Target for Antiepileptic Drugs: A Historical Overview Focused on GABA Transporters
Schousboe, Arne, Madsen, K. K., Barker-Haliski, M. L. & White, H. S., 2014, In: Neurochemical Research. 39, 10, p. 1980-1987 8 p.Research output: Contribution to journal › Journal article › peer-review
- 2013
- Published
Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA
Schousboe, Arne, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 15 Aug 2013, In: Frontiers in Endocrinology. 4, 102.Research output: Contribution to journal › Journal article › peer-review
- Published
Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures
Dadsetan, S., Kukolj, E., Bak, Lasse Kristoffer, Sørensen, M., Ott, P., Vilstrup, H., Schousboe, Arne, Keiding, S. & Waagepetersen, Helle S., Aug 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 8, p. 1235-41 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry
Müller, M. S., Obel, L. L. F., Waagepetersen, Helle S., Schousboe, Arne & Bak, Lasse Kristoffer, Jun 2013, In: Neurochemical Research. 38, 6, p. 1260-5 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases
Zaganas, I., Pajecka, K., Nielsen, C. W., Schousboe, Arne, Waagepetersen, Helle S. & Plaitakis, A., Jun 2013, In: Metabolic Brain Disease. 28, 2, p. 127-131 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization
Pajecka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, Lasse Kristoffer, Schousboe, Arne, Plaitakis, A. & Waagepetersen, Helle S., 26 Apr 2013, In: Neurochemical Research. 39, 3, p. 487-499Research output: Contribution to journal › Journal article › peer-review
- Published
Selective mGAT2 (BGT-1) GABA Uptake Inhibitor: Design, synthesis and pharmacological characterization
Vogensen, S. B., Jørgensen, L., Madsen, K. K., Borkar, N. N., Wellendorph, Petrine, Skovgaard-Petersen, J., Schousboe, Arne, White, H. S., Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 11 Feb 2013, In: Journal of Medicinal Chemistry. 56, 5, p. 2160-2164 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake
Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., Jan 2013, In: Hepatology. 57, 1, p. 258-65 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Amino acid neurotransmitter synthesis and removal
Schousboe, Arne, Bak, Lasse Kristoffer, Madsen, K. K. & Waagepetersen, Helle S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (eds.). 3. ed. Oxford: Oxford University Press, p. 443-456 14 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Discovery of a subtype-selective of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile
Kragholm, B., Kvist, T., Madsen, K. K., Jørgensen, L., Vogensen, S. B., Schousboe, Arne, Clausen, Rasmus Prætorius, Jensen, Anders A. & Bräuner, Hans, 2013, In: Biochemical Pharmacology. 86, p. 521-528Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamate neurotoxicity related to energy failure
Schousboe, Arne, 2013, Handbook of neurotoxicity. Kostrzewa, R. (ed.). New York: Springer, p. 1299-1310 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Impairment of short term memory in rats with hepatic encephalopathy due to bile duct ligation
Leke, R., Oliveira, D., Forgiarini, L., Escobar, T., Hammes, T., Meyer, F., Silveira, T., Keiding, S. & Schousboe, Arne, 2013, In: Metabolic Brain Disease. 28, 2, p. 187-192 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Interorgan metabolism of ornithine phenylacetate (OP)-A novel strategy for treatment of hyperammonemia
Dadsetan, S., Sørensen, M., Bak, Lasse Kristoffer, Vilstrup, H., Ott, P., Schousboe, Arne, Jalan, R., Keiding, S. & Waagepetersen, Helle S., 2013, In: Biochemical Pharmacology. 85, 1, p. 115-23 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Reply to letter to the editor by Zheng G et al. Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy
Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., 2013, In: Hepatology. 58, 2, p. 833-834Research output: Contribution to journal › Comment/debate › peer-review
- 2012
- Published
Energy Metabolism of the Brain
McKenna, M. C., Dienel, G. A., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 1 Dec 2012, Basic Neurochemistry. Elsevier, p. 200-231 32 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Procedure for calculation of potency and efficacy for ligands acting on Gs- and Gi-coupled receptors
Meier, E., Schousboe, Arne & Belhage, B., Dec 2012, In: Neurochemical Research. 37, 12, p. 2767-2775 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Primary cultures of astrocytes: their value in understanding astrocytes in health and disease
Lange, S. C., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Nov 2012, In: Neurochemical Research. 37, 11, p. 2569-88 20 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level
Obel, L. L. F., Müller, M. S., Walls, Anne Byriel, Sickmann, H. M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2 Mar 2012, In: Frontiers in Neuroenergetics. 4, 15 p.Research output: Contribution to journal › Review › peer-review
- Published
(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction
Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366Research output: Contribution to journal › Journal article › peer-review
- Published
Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation
Kreft, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2012, In: A S N Neuro. 4, 3, p. 187 199 p.Research output: Contribution to journal › Review › peer-review
- Published
Brain energy and ammonia metabolism
Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Vol. 1. p. 129-144 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model
Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2012, In: Neurochemistry International. 60, 3, p. 267-75 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation
Brekke, E., Walls, Anne Byriel, Nørfeldt, L., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Glia. 60, 1, p. 147-58 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of adrenergic agents on intracellular ca(2+) homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity
Obel, L. L. F., Andersen, K. M. H., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurotoxicity Research. 21, 4, p. 405-17 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Glial cells in (patho)physiology
Parpura, V., Heneka, M. T., Montana, V., Oliet, S. H. R., Schousboe, Arne, Haydon, P. G., Stout Jr., R. F., Spray, D. C., Andreas, R., Pannicke, T., Pekny, M., Pekna, M., Zorec, R. & Verkhratsky, A., 2012, In: Journal of Neurochemistry. 121, 1, p. 4-27 24 p.Research output: Contribution to journal › Review › peer-review
- Published
Impairment of the organization of locomotor and exploratory behaviors in bile duct-ligated rats
Leke, R., de Oliveira, D. L., Mussulini, B. H. M., Pereira, M. S., Kazlauckas, V., Mazzini, G., Hartmann, C. R., Silveira, T. R., Simonsen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Keiding, S., Schousboe, Arne & Portela, L. V., 2012, In: P L o S One. 7, 5, p. e36322Research output: Contribution to journal › Journal article › peer-review
- Published
Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons
Bak, Lasse Kristoffer, Obel, L. L. F., Walls, Anne Byriel, Schousboe, Arne, Faek, S. A. A., Jajo, F. S. & Waagepetersen, Helle S., 2012, In: A S N Neuro. 4, 3, p. 151-160Research output: Contribution to journal › Journal article › peer-review
- Published
Quantitative importance of the pentose phosphate pathway determined by incorporation of 13C from [2-13C]- and [3-13C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons
Brekke, E. M., Walls, Anne Byriel, Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 9, p. 1788-1799 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Studies of brain metabolism: a historical perspective
Schousboe, Arne, 2012, Neural metabolism in vivo. Choi, I-Y. & Gruetter, R. (eds.). New York: Springer Publishing Company, p. 909-920 12 p. (Advances in Neurobiology, Vol. 4).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons
Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Journal of Neuroscience Research. 90, 9, p. 1768-75 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate
Jensen, Dorte Skytt, Klawonn, A. M., Strid, M. H., Pajecka, K., Patruss, Y., Quintana-Cabrera, R., Bolanos, J. P., Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurochemistry International. 61, 4, p. 490-497Research output: Contribution to journal › Journal article › peer-review
- 2011
- Published
Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source
Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Jajo, F. S., Faek, S. A. A. & Waagepetersen, Helle S., 1 Dec 2011, In: Journal of Neuroscience Research. 89, 12, p. 1926-34 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons
Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In: Neurochemistry International. 59, 4, p. 482-8 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects
Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77Research output: Contribution to journal › Journal article › peer-review
- Published
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol
Madsen, K. K., Ebert, B., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 1 Jul 2011, In: Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 214-219Research output: Contribution to journal › Journal article › peer-review
- Published
Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice
Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In: Epilepsy Research. 95, 1-2, p. 70-81Research output: Contribution to journal › Journal article › peer-review
- Published
Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating
Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In: Nature Neuroscience. 14, 6, p. 727-735Research output: Contribution to journal › Journal article › peer-review
- Published
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy
Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine
Leke, R., Bak, Lasse Kristoffer, Anker, M., Melø, T. M., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Apr 2011, In: Neurotoxicity Research. 19, 3, p. 496-510 15 p.Research output: Contribution to journal › Journal article › peer-review
- Published
13C NMR spectroscopy and mass spectrometry analysis of intermediary metabolism in cultured neural cells
Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 18 Mar 2011, Cell Culture Techniques. Aschner, M., Sunol, C. & Bal-Price, A. (eds.). p. 403-415 13 p. (Neuromethods, Vol. 56).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Brain energy and ammonia metabolism
Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2011, Functional molecular imaging in hepatology. Bussum, The Netherlands: Bentham Science Publishers, p. 129-144Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
GABA transport inhibitors and seizure protection: the past and future
Schousboe, Arne, Madsen, K. K. & White, S., 2011, In: Future Medicinal Chemistry. 3, 2, p. 183-187 5 p.Research output: Contribution to journal › Review › peer-review
- Published
Glutamate and glutamine in brain disorders
Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2011, Neurochemical mechanisms in diseases. Blass, J. P. (ed.). New York: Springer Publishing Company, Vol. 1. p. 195-212 (Advances in Neurobiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Hippocampal betaine/GABA transporter mRNA expression is not regulated by inflammation or dehydration post-status epilepticus
Rowley, N. M., Smith, M. D., Lamb, J. G., Schousboe, Arne & White, H. S., 2011, In: Journal of Neurochemistry. 117, 1, p. 82-90Research output: Contribution to journal › Journal article › peer-review
- Published
Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine
Walls, Anne Byriel, Eyjolfsson, E. M., Smeland, O. B., Nilsen, L. H., Schousboe, I., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 494-503 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Simple cellemodeller for kommunikation i hjernen
Schousboe, Arne, Madsen, K. K. & Pickering, Darryl S, 2011, Bioteknologi - en temabog. Gasbjerg, P., Jensen, G. & Sørensen, A. (eds.). Aarhus Danmark: Systime Academic, p. 98-107 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- 2010
- Published
A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures
Suñol, C., Babot, Z., Cristòfol, R., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, Sep 2010, In: Neurochemical Research. 35, 9, p. 1384-1390 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes
Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Bouman, S. D. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. s1, p. 288-289Research output: Contribution to journal › Conference abstract in journal
- Published
Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex
Jensen, Dorte Skytt, Madsen, K. K., Pajecka, K., Schousboe, Arne & Waagepetersen, Helle S., 2010, In: Neurochemical Research. 35, 12, p. 2043-2052 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Functional importance of the astrocytic glycogen-shunt and glycolysis for maintenance of an intact intra/extracellular glutamate gradient
Schousboe, Arne, Sickmann, H. M., Walls, Anne Byriel, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 2010, In: Neurotoxicity Research. 18, 1, p. 94-9 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
GABA-syntese - en vigtig brik for kontrol af epilepsi
Walls, Anne Byriel, Schousboe, Arne & Waagepetersen, Helle S., 2010, In: Lægemiddelforskning. 2010, p. 31-33Research output: Contribution to journal › Journal article
- Published
GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity
Walls, Anne Byriel, Nilsen, L. H., Eyjolfsson, E. M., Vestergaard, H. T., Hansen, S. L., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. 115, 6, p. 1398–1408Research output: Contribution to journal › Journal article › peer-review
- Published
Glial cell biology: neuronal-glial interaction in nutrition and amino-acid-mediated neurotransmission
Schousboe, Arne & Waagepetersen, Helle S., 2010, The newborn brain: Neuroscience and clinical applications. Lagercrantz, H., Hanson, M. A., Ment, L. R. & Peebles, D. M. (eds.). 2 ed. Cambridge: Cambridge University Press, p. 121-128Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs
Madsen, K. K., White, H. S. & Schousboe, Arne, 2010, In: Pharmacology & Therapeutics. 125, 3, p. 394-401Research output: Contribution to journal › Journal article › peer-review
- Published
Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis
Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 8, p. 1527-37 10 p.Research output: Contribution to journal › Journal article › peer-review
- 2009
- Published
Erratum: Demonstration of neuron-glia transfer of precursors for gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex (Neurochem Res (2008) 33:26292635;DOI 10.1007/s11064-008-9814-6)
Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 1 Dec 2009, In: Neurochemical Research. 34, 12, 1 p.Research output: Contribution to journal › Comment/debate › peer-review
- Published
Aspartate-glutamate homeostasis in cerebellar neurons changes when shifting from glucose to beta-hydroxybutyrate as substrate
Lund, Trine Meldgaard, Clausen, M., Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 291-291Research output: Contribution to journal › Conference abstract in journal
- Published
Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons
Lund, Trine Meldgaard, Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 110, 1, p. 80-91 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Functional significance of brain glycogen in sustaining glutamatergic neurotransmission
Sickmann, H. M., Walls, Anne Byriel, Schousboe, Arne, Bouman, S. D. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 80-86 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
GABA synthesis from ß-hydroxybutyrate and glucose is differentially affected by neuronal activity in cultured GABAergic neurons
Lund, Trine Meldgaard, Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s2, p. 95Research output: Contribution to journal › Conference abstract in journal
- Published
GAD65 is essential for the maintenance of GABA homeostasis
Smeland, O., Walls, A. B., Eyolfsson, E. M., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2009, In: Journal of Neurochemistry. p. 51-51Research output: Contribution to journal › Conference abstract in journal
- Published
GAD65 is essential for the maintenance of GABA homeostasis
Walls, A. B., Eyolfsson, E. M., Sonnewald, U., Vestergaard, H. T., Hansen, S. L., Schousboe, I. E., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 292-292Research output: Contribution to journal › Conference abstract in journal
- Published
Gamma-aminobutyric acid (GABA)
Schousboe, Arne & Waagepetersen, Helle S., 2009, Encyclopedia of neuroscience. Squire, L. R. (ed.). Academic Press, Vol. 4. p. 511-515Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Glial glutamate and GABA metabolism
Waagepetersen, Helle S. & Schousboe, Arne, 2009, Encyclopedia of neuroscience. Squire, L. R. (ed.). Academic Press, Vol. 4. p. 789-792Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Glial modulation of excitability via glutamate and GABA transporters
Schousboe, Arne & White, H. S., 2009, Encyclopedia of basic epilepsy research. Schwartzkroin, P. A. (ed.). Academic Press, Vol. 1. p. 397-401Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Glutamate uptake triggers transporter-mediated GABA release from astrocytes
Héja, L., Barabás, P., Nyitrai, G., Kékesi, K. A., Lasztóczi, B., Toke, O., Tárkányi, G., Madsen, K. K., Schousboe, Arne, Dobolyi, Á., Palkovits, M. & Kardos, J., 2009, In: PLoS ONE. 4, 9, p. e7153-e7153Research output: Contribution to journal › Journal article › peer-review
- Published
Impact of the malate-aspartate shuttle in glutamate neurotransmission
Waagepetersen, Helle S., Bak, Lasse Kristoffer, Lund, Trine Meldgaard, Walls, A. B., Sonnewald, U. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. s1, p. 9Research output: Contribution to journal › Conference abstract in journal
- Published
Knockdown of GDH indicates its potential impact in sustaining glutamate homeostasis and neurotransmission
Klawonn, A. M., Bolanos, J. P., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. s2, p. 105Research output: Contribution to journal › Conference abstract in journal
- Published
Low Cerebral Oxygen Consumption and Blood Flow in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy
Iversen, P., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Vafaee, M. S., Borghammer, P., Mouridsen, K., Jensen, S. B., Vilstrup, H., Schousboe, Arne, Ott, P., Gjedde, Albert & Keiding, S., 2009, In: Gastroenterology. 136, 3, p. 863-871Research output: Contribution to journal › Journal article › peer-review
- Published
Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia
Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Metabolic Brain Disease. 24, 1, p. 135-145Research output: Contribution to journal › Journal article › peer-review
- Published
Metabolic profiles of the brains of Zucker Diabetic Fatty, Zucker Obese and Sprague-Dawley rats and the involvement of glycogen metabolism
Sickmann, H. M., Bouman, S. D., Schousboe, Arne, Tracey, W. R. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 293-293Research output: Contribution to journal › Conference abstract in journal
- Published
Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels
Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne, Ring, A., Sonnewald, U. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 87-93 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Neuronal metabolism in GAD65 knockout mice is compromised and not susceptible to kainic acid
Walls, A. B., Eyjolfsson, E. M., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. Suppl. 2, p. 123Research output: Contribution to journal › Conference abstract in journal
- Published
Prenatal stress effect on glutamate metabolism, evaluated with mass espectroscopy-liquid cromatography
Adrover, E., Katunar, M. R., Waagepetersen, Helle S., Schousboe, Arne & Antonelli, M. C., 2009, In: Journal of Neurochemistry. Suppl. 2, p. 172-172Research output: Contribution to journal › Conference abstract in journal
- Published
Reduced cerebral blood flow and oxygen consumption in cirrhosis patients with acute hepatic encephalopathy
Keiding, S., Iversen, P., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Gjedde, A., Schousboe, Arne & Vilstrup, H., 2009, In: Journal of Neurochemistry. s1, p. 269-270Research output: Contribution to journal › Conference abstract in journal
- Published
Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents
Walls, Anne Byriel, Heimbürger, C., Bouman, S., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Neuroscience. 158, 1, p. 284-292Research output: Contribution to journal › Journal article › peer-review
- Published
Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs
Madsen, K. K., Clausen, Rasmus Prætorius, Larsson, O. M., Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 139-44Research output: Contribution to journal › Journal article › peer-review
- 2008
- Published
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. Structure-activity relationships and identification of potent and selective iGluR5 modulators
Butini, S., Pickering, Darryl S, Morelli, E., Coccone, S. S., Trotta, F., De Angelis, M., Guarino, E., Fiorini, I., Campiani, G., Novellino, E., Schousboe, Arne, Christensen, J. K. & Gemma, S., 2008, In: Journal of Medicinal Chemistry. 51, 20, p. 6614-8Research output: Contribution to journal › Journal article › peer-review
- Published
Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity
Walls, Anne Byriel, Sickmann, H. M., Brown, A., Bouman, S. D., Ransom, B., Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Journal of Neurochemistry. 105, p. 1462-1470Research output: Contribution to journal › Journal article › peer-review
- Published
Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex
Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635Research output: Contribution to journal › Journal article › peer-review
- Published
GABA Neurotransmission: An overview
Schousboe, Arne & Waagepetersen, Helle S., 2008, Handbook of Neurochemistry and Molecular Neurobiology: Neurotransmitter Systems. Vizi, E. S. (ed.). The Netherlands: Springer Publishing Company, p. 213-226Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
GABA-transportører: håb om bedre epilepsibehandling
Madsen, K. K., Clausen, Rasmus Prætorius, Larsson, O. M. & Schousboe, Arne, 2008, In: Lægemiddelforskning. p. 22-24Research output: Contribution to journal › Journal article
- Published
Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)
Smith, M. D., Saunders, G. W., Clausen, Rasmus Prætorius, Frølund, Bente, Krogsgaard-Larsen, Povl, Larsson, O. M., Schousboe, Arne, Wilcox, K. S. & White, H. S., 2008, In: Epilepsy Research. 79, 1, p. 6-13Research output: Contribution to journal › Journal article › peer-review
- Published
- Published
Metabolism of [1,6-13C]glucose and [U-13C]glutamine and depolarization induced GABA release in superfused mouse cerebral cortical mini-slices
Waagepetersen, Helle S., Døring, S. & Schousboe, Arne, 2008, In: Neurochemical Research. 33, 8, p. 1610-1617Research output: Contribution to journal › Journal article › peer-review
- Published
Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix
Bak, Lasse Kristoffer, Zieminska, E., Waagepetersen, Helle S., Schousboe, Arne & Albrecht, J., 2008, In: Neurochemical Research. 33, 2, p. 273-278Research output: Contribution to journal › Journal article › peer-review
- Published
Pharmacological manipulation of extrasynaptic GABA transporters: implications for epilepsy management
Madsen, K. K., Ebert, B., Larsson, O. M., Clausen, Rasmus Prætorius, Schousboe, Arne & White, H. S., 2008, In: Epilepsia. Suppl. 7, p. 347Research output: Contribution to journal › Conference abstract in journal
- Published
Regulation of excitation by GABA neurotransmission: Focus on metabolism and transport
Madsen, K. K., Larsson, O. M. & Schousboe, Arne, 2008, In: Results and Problems in Cell Differentiation. 44, p. 201-221Research output: Contribution to journal › Journal article › peer-review
- Published
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency
Beich-Frandsen, M., Pickering, Darryl S, Mirza, Osman Asghar, Johansen, Tommy Nørskov, Greenwood, J., Vestergaard, Bente, Schousboe, Arne, Gajhede, Michael, Liljefors, T. & Kastrup, Jette Sandholm Jensen, 2008, In: Journal of Medicinal Chemistry. 51, 5, p. 1459-63Research output: Contribution to journal › Journal article › peer-review
- Published
The micro-architecture of the cerebral cortex: Functional neuroimaging models and metabolism
Riera, J. J., Schousboe, Arne, Waagepetersen, Helle S., Howarth, C. & Hyder, F., 2008, In: NeuroImage. 40, 4, p. 1436-1459Research output: Contribution to journal › Review
- 2007
- Published
Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate
Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., Dec 2007, In: Neurotoxicity Research. 12, 4, p. 263-8 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Actions of toxins on cerebral metabolism at cellular level
Sonnewald, U., Syversen, T., Schousboe, Arne, Waagepetersen, Helle S. & Aschner, M., 2007, Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes. Lajtha, A., Gibson, G. E. & Dienel, G. A. (eds.). 3rd. ed. ed. Berlin: Springer, Vol. 3. p. 569-585Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure
Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neuroscience Research. 86, p. 3465-3470Research output: Contribution to journal › Journal article › peer-review
- Published
Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes
Bak, Lasse Kristoffer, Waagepetersen, Helle S., Melø, T. M., Schousboe, Arne & Sonnewald, U., 2007, In: Neurochemical Research. 32, p. 671-680Research output: Contribution to journal › Journal article › peer-review
- Published
Energy substrates to support glutamatergic and GABAergic synaptic function: Role of glycogen, glucose and lactate
Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., 2007, In: Neurotoxicity Research. 12, 4, p. 263-268Research output: Contribution to journal › Journal article › peer-review
- Published
Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes
Jørgensen, L., van Beek, J., Lund, S., Schousboe, Arne & Badolo, L., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 181-189Research output: Contribution to journal › Journal article › peer-review
- Published
Functional and pharmacological aspects of GABA transporters
Madsen, K., White, H. S., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O. M., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2007, Handbook of nerochemistry and molecular neurobiology: Neural membranes and transport. Lajtha, A. & Reith, M. E. A. (eds.). 3rd. ed. Berlin: Springer, Vol. 3. p. 285-304Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
GABA transporter localization to lipid raft membrane microdomains in neurons and astrocytes
Madsen, K. K., Pickering, Darryl S, Hansen, G. H., Danielsen, E. M., Larsson, O. M. & Schousboe, Arne, 2007, In: Journal of Neurochemistry. 102, s1, p. 46Research output: Contribution to journal › Conference abstract in journal
- Published
GABA: Homeostatic and pharmacological aspects
Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Progress in Brain Research. 160, p. 9-19Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamine in the central nervous system: function and dysfunction
Albrecht, J., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 2007, In: Frontiers in Bioscience. 12, p. 332-343Research output: Contribution to journal › Journal article › peer-review
- Published
Glutamine, glutamate and GABA: metabolic aspects
Waagepetersen, Helle S., Sonnerwald, U. & Schousboe, Arne, 2007, Handbook of neurochemistry and molecular neurobiology: amino acids and peptides in the nervous system. Lajtha, A., Oja, S. S., Schousboe, A. & Saransaari, P. (eds.). 3rd. ed. Berlin: Springer, p. 1-21Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
One third of glycolytic activity in astrocytes depends on the operation of the glycogen shunt
Walls, Anne Byriel, Heimbürger, C. M., Sickmann, H. M., Bouman, S. D., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 119Research output: Contribution to journal › Conference abstract in journal
- Published
Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid
Hald, H., Naur, P., Pickering, Darryl S, Sprogøe, D., Madsen, Ulf, Timmermann, D. B., Ahring, P. K., Liljefors, T., Schousboe, Arne, Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In: Journal of Biological Chemistry. 282, 35, p. 25726-25736Research output: Contribution to journal › Journal article › peer-review
- Published
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes
Johansen, M. L., Bak, Lasse Kristoffer, Schousboe, Arne, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Gjedde, A., Ott, P. & Waagepetersen, Helle S., 2007, In: Neurochemistry International. 50, p. 1042-1051Research output: Contribution to journal › Journal article › peer-review
- Published
The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex
Lovatt, D., Sonnewald, U., Waagepetersen, Helle S., Schousboe, Arne, He, W., Lin, J. H., Han, X., Takano, T., Wang, S., Sim, F. J., Goldman, S. A. & Nedergaard, M., 2007, In: Journal of Neuroscience. 27, 45, p. 12255-12266Research output: Contribution to journal › Journal article › peer-review
- Published
ß-hydroxybutyrate and glucose metabolism is differently affected by neuronal activity
Lund, Trine Meldgaard, Clausen, M., Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 116Research output: Contribution to journal › Conference abstract in journal
- 2006
- Published
Structure-Activity Relationship and Pharmacology of γ-Aminobutyric Acid (GABA) Transport Inhibitors
Clausen, Rasmus Prætorius, Madsen, K., Larsson, O. M., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 1 Dec 2006, GABA. Enna, S. J. (ed.). p. 265-284 20 p. (Advances in Pharmacology, Vol. 54).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons
Bak, Lasse Kristoffer, Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., Oct 2006, In: Journal of Cerebral Blood Flow and Metabolism. 26, 10, p. 1285-97 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer
Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., Aug 2006, In: Journal of Neurochemistry. 98, 3, p. 641-53 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Neurotransmitter transporters: molecular function of important drug targets
Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, Arne, Jul 2006, In: Trends in Pharmacological Sciences. 27, 7, p. 375-83 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools
Sonnewald, U., Kortner, T. M., Qu, H., Olstad, E., Suñol, C., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 7 Mar 2006, In: Neurochemistry International. 48, 6-7, p. 572-8 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A novel selective γ-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS
Frølund, Bente, Clausen, Rasmus Prætorius, Larsson, O. M., Schousboe, Arne, Krogsgaard-Larsen, Povl & White, H. S., 2006, In: Neurochemistry International. 48, p. 637–642Research output: Contribution to journal › Journal article › peer-review
- Published
Effect of topiramate and dBcAMP on expression of the glutamate transporters GLAST and GLT-1 in astrocytes cultured separately, or together with neurons
Poulsen, C. F., Schousboe, E. I., Sarup, A., White, H. S. & Schousboe, Arne, 2006, In: Neurochemistry International. 48, Sp. Iss. SI 6-7, p. 657-661 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Functional and Pharmacological Aspects of GABA Transporters
Madsen, K., White, S. H., Clausen, Rasmus Prætorius, Larsson, O. M., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2006, Handbook of Neurochemistry and Molecular neurobiology. p. 1-17Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Structure-Activity Relationships of Selective GABA Uptake Inhibitors
Høg, S., Greenwood, J., Madsen, K. B., Larsson, O. M., Frølund, Bente, Schousboe, Arne, Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 2006, In: Current Topics in Medicinal Chemistry. 6, 17, p. 1861–1882Research output: Contribution to journal › Journal article › peer-review
- Published
Structure–Activity Relationship and Pharmacology of γ‐Aminobutyric Acid Transport Inhibitor
Clausen, Rasmus Prætorius, Madsen, K., Larsson, O. M., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2006, GABA. Enna, S. (ed.). Vol. 54. p. 265–284 (Advances in Pharmacology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209
Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In: Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.Research output: Contribution to journal › Journal article › peer-review
- 2005
- Published
Design, synthesis, and characterisation of selective GABA transport inhibitors
Clausen, Rasmus Prætorius, Moltzen, E., Perregaard, J., Lenz, S., Sanchez, S., Frølund, Bente, Bolvig, T., Sarup, A., Larsson, O., White, H., Schousboe, Arne & Krogsgaard-Larsen, Povl, Aug 2005, In: Journal of Neurochemistry. 94, p. 150-150Research output: Contribution to journal › Conference abstract in journal
- Published
Effect of tiagabine and EF1502 on phenytoin-resistant spontaneous bursts in the entorhinal cortex of slices from kainic acid-treated rats
Smith-Yockman, M., Saunders, G., Wilcox, K., Larsson, O., Clausen, Rasmus Prætorius, Frølund, Bente, Schousboe, Arne & White, H., Aug 2005, In: Journal of Neurochemistry. 94, p. 256-256Research output: Contribution to journal › Conference abstract in journal
- Published
Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter
Brown, A. M., Sickmann, H. M., Fosgerau, K., Lund, Trine Meldgaard, Schousboe, Arne, Waagepetersen, Helle S. & Ransom, B. R., 2005, In: Journal of Neuroscience Research. 79, 1-2, p. 74-80 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Differential effects of two GABA transport inhibitors, tiagabine and EF-1502, on phenytoin-resistant spontaneous bursting in the entorhinal cortex of slices from kainic acid treated rats
Smith-Yockman, M., Saunders, G., Wilcox, K., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O., Schousboe, Arne & White, H., 2005, In: Epilepsia. 46, p. 188-188Research output: Contribution to journal › Conference abstract in journal
- Published
Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP
Nielsen, B. B., Pickering, Darryl S, Greenwood, J. R., Brehm, L., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: FEBS Journal. 272, 7, p. 1639-48 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
First Demonstration of a Functional Role for CNS Betaine/GABA Transporter (mGAT2) Based on Synergistic Anticonvulsant Action Among Inhibitors of mGAT1 and mGAT2
White, S., Watson, W. P., Hansen, S. L., Slough, S., Perregård, J., Sarup, A., Bolvig, T., Petersen, G., Larsson, O. M., Clausen, Rasmus Prætorius, Frølund, Bente, Falch, E., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2005, In: The Journal of Pharmacology and Experimental Therapeutics. 312, p. 866–874Research output: Contribution to journal › Journal article › peer-review
- Published
Lipid raft localization of GABA A receptor and Na+, K+-ATPase in discrete microdomain clusters in rat cerebellar granule cells
Dalskov, S., Immerdal, L., Niels-Christiansen, L. W., Hansen, Gert Helge, Schousboe, Arne & Danielsen, E. M., 2005, In: Neurochemistry International. 46, 6, p. 489-99 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino- 4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues
Clausen, Rasmus Prætorius, Moltzen, E. K., Perregaard, J., Lenz, S., Sanchez, C., Falch, E., Frølund, Bente, Bolvig, T., Sarup, A., Larsson, O. M., Schousboe, Arne & Krogsgaard-Larsen, Povl, 2005, In: Bioorganic & Medicinal Chemistry. 13, p. 895–908Research output: Contribution to journal › Journal article › peer-review
- Published
Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2
Frandsen, A., Pickering, Darryl S, Vestergaard, Bente, Kasper, C., Nielsen, B. B., Greenwood, J. R., Campiani, G., Fattorusso, C., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: Molecular Pharmacology. 67, 3, p. 703-13 10 p.Research output: Contribution to journal › Journal article › peer-review
- 2004
- Published
Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures
Bak, Lasse Kristoffer, Sickmann, H. M., Schousboe, Arne & Waagepetersen, Helle S., 4 Dec 2004, In: Journal of Neuroscience Research. 79, 1-2, p. 88-96 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission
Schousboe, Arne, Sarup, A., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Larsson, O. M., Sep 2004, In: Neurochemistry International. 45, 4, p. 521-7 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of astrocytes in depolarization-coupled release of glutamate in cerebellar cultures
Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, Jan 2004, In: Neurochemical Research. 29, 1, p. 257-65 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1
Lund, Trine Meldgaard, Christensen, E., Kristensen, Anders Skov, Schousboe, Arne & Lund, Allan Meldgaard, 2004, In: Journal of Neuroscience Research. 77, 1, p. 143-7 5 p.Research output: Contribution to journal › Journal article › peer-review
- 2003
- Published
Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using DL-threo-beta-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and cytoplasmic pools
Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 14 May 2003, In: Neurochemistry International. 43, 4-5, p. 417-24 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)
Bjerrum, E. J., Kristensen, Anders Skov, Pickering, D. S., Greenwood, J. R., Nielsen, Birgitte, Liljefors, T., Schousboe, Arne, Bräuner, Hans, Madsen, Ulf & Pickering, Darryl S, 2003, In: Journal of Medicinal Chemistry. 46, 11, p. 2246-9 3 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazol (exo-THPO) and its N-substituted analogs on GABA transport in cultured neurons and astrocytes and by the four cloned mouse GABA transporters
sarup, A., Larsson, O. M., Bolvig, T., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2003, In: Neurochemistry International. 43, p. 445–451Research output: Contribution to journal › Journal article › peer-review
- 2002
- Published
Point mutation in the first transmembrane region of the β2 subunit of the γ-aminobutyric acid type A receptor alters desensitization kinetics of γ-aminobutyric acid- and anesthetic-induced channel gating
Christine Engblom, A., Carlson, B. X., Olsen, R. W., Schousboe, Arne & Kristiansen, Uffe, 17 May 2002, In: Journal of Biological Chemistry. 277, 20, p. 17438-17447 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Correlation between Anticonvulsant Activity and Inhibitory Action on Glial -Aminobutyric Acid Uptake of the Highly Selective Mouse -Aminobutyric Acid Transporter 1 Inhibitor 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and Its N-Alkylated Analogs
White, S., Sarup, A., Bolvig, T., Petersen, G., Nelson, N., Pickering, Darryl S, Larsson, O. M., Frølund, Bente, Falch, E., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2002, In: Journal of Pharmacology and Experimental Therapeutics. 302, p. 636–644Research output: Contribution to journal › Journal article › peer-review
- 2001
- Published
Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties
Campiani, G., Morelli, E., Nacci, V., Fattorusso, C., Ramunno, A., Novellino, E., Greenwood, J., Liljefors, T., Griffiths, R., Sinclair, C., Reavy, H., Kristensen, A. S., Pickering, Darryl S, Schousboe, Arne, Cagnotto, A., Fumagalli, E., Mennini, T. & Pickering, Darryl S, 2001, In: Journal of Medicinal Chemistry. 44, 26, p. 4501-4 3 p.Research output: Contribution to journal › Journal article › peer-review
Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization
Banke, T. G., Greenwood, J. R., Christensen, J. K., Liljefors, T., Traynelis, S. F., Schousboe, Arne, Pickering, D. S. & Pickering, D., 2001, In: Journal of Neuroscience. 21, 9, p. 3052-62 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons
Timmermann, D. B., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 2001, In: International Journal of Developmental Neuroscience. 19, 1, p. 1-10 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Molecular determinants of desensitization and assembly of the chimeric GABA(A) receptor subunits (alpha1/gamma2) and (gamma2/alpha1) in combinations with beta2 and gamma2
Elster, L., Kristiansen, Uffe, Pickering, Darryl S, Olsen, R. W. & Schousboe, Arne, 2001, In: Neurochemistry International. 38, 7, p. 581-92 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons
Jensen, J. B., Lund, Trine Meldgaard, Timmermann, D. B., Schousboe, Arne & Pickering, Darryl S, 2001, In: Journal of Neuroscience Research. 65, 3, p. 267-277 11 p.Research output: Contribution to journal › Journal article › peer-review
- 2000
- Published
Determination of the phospholipid precursor of anandamide and other N- acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons
Hansen, H. H., Schousboe, Arne, Hansen, Harald S. & Hansen, S. H., 1 Jan 2000, In: Journal of Neurochemistry. 75, 2, p. 861-871 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A single glycine residue at the entrance to the first membrane-spanning domain of the γ-aminobutyric acid type a receptor β2 subunit affects allosteric sensitivity to GABA and anesthetics
Carlson, B. X., Engblom, A. C., Kristiansen, Uffe, Schousboe, Arne & Olsen, R. W., 2000, In: Molecular Pharmacology. 57, 3, p. 474-484 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Agonist discrimination between AMPA receptor subtypes
Coquelle, T., Christensen, J. K., Banke, T. G., Madsen, U., Schousboe, Arne & Pickering, Darryl S, 2000, In: NeuroReport. 11, 12, p. 2643-8 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Depolarization-induced release of [(3)H]D-aspartate from GABAergic neurons caused by reversal of glutamate transporters
Jensen, J. B., Pickering, Darryl S, Schousboe, Arne & Pickering, Darryl S, 2000, In: International Journal of Developmental Neuroscience. 18, 2-3, p. 309-15 6 p.Research output: Contribution to journal › Journal article › peer-review
- 1999
- Published
Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity
Hansen, Harald S., Moesgaard, B., Hansen, H. H., Schousboe, Arne & Petersen, G., 1 Jan 1999, In: Lipids. 34, 6 SUPPL.Research output: Contribution to journal › Journal article › peer-review
- Published
Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity
Bolvig, T., Larsson, O. M., Pickering, Darryl S, Nelson, N., Falch, E., Krogsgaard-Larsen, Povl, Schousboe, Arne & Pickering, Darryl S, 1999, In: European Journal of Pharmacology. 375, 1-3, p. 367-74 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Differential localization of voltage-gated calcium channels in neurites and somata of cultured neocortical neurons.
Timmermann, D., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 1999, In: Journal of Neurochemistry. 73, Suppl, p. 127 1 p.Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Role of desensitization and subunit expression for kainate receptor-mediated neurotoxicity in murine neocortical cultures
Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1999, In: Journal of Neuroscience Research. 55, 2, p. 208-17 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Selective Inhibitors of Glial GABA Uptake: Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues
Falch, E., Frølund, Bente, Perregaard, Sanchez, C., Søkilde, B., Buur, A., Hansen, A., Frydenvang, Karla Andrea, Brehm, L., Bolvig, T., Larsson, O. M., Schousboe, Arne & Krogsgaard-Larsen, Povl, 1999, In: Journal of Medicinal Chemistry. 42, p. 5402–5414Research output: Contribution to journal › Journal article › peer-review
- 1998
- Published
Functional properties of glycine receptors expressed in primary cultures of mouse cerebellar granule cells
Elster, L., Banke, T., Kristiansen, Uffe, Schousboe, Arne & Wahl, P., May 1998, In: Neuroscience. 84, 2, p. 519-28 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization
Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1998, In: Neurochemistry International. 32, 5-6, p. 505-13 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of .....
Bacon, C. L., Berezin, V., Bode, G., Bock, E., Bojic, U., Doherty, P., Edvardsen, K., Ehlers, K., Ellerbeck, U., Julien, P., Kawa, A., Maar, T., Nau, H., Pirovano, R., Regan, C., Schousboe, Arne, Spezia, F., Walsh, F. S. & Williams, E. J., 1998, In: Toxicology in Vitro. 12, p. 101-109Research output: Contribution to journal › Journal article › peer-review
- Published
Development of calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining
Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1998, In: Journal of Neuroscience Research. 54, 2, p. 273-81 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of gamma-aminobutyric acid (GABA) on synaptogenesis and synaptic function
Belhage, B., Hansen, Gert Helge, Elster, L. & Schousboe, Arne, 1998, In: Perspectives of Developmental Neurobiology. 5, 2-3, p. 235-46 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells
Maar, T. E., Lund, Trine Meldgaard, Gegelashvili, G., Hartmann-Petersen, Rasmus, Moran, M. J., Pasantes-Morales, H., Berezin, V., Bock, E. & Schousboe, Arne, 1998, In: Amino Acids. 15, 1, p. 77-88 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Pharmacological properties of homomeric and heteromeric GluR1o and GluR3o receptors
Nielsen, B. S., Banke, T. G., Schousboe, Arne & Pickering, Darryl S, 1998, In: European Journal of Pharmacology. 360, 2-3, p. 227-38 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Spectral components of cytosolic [Ca2+] spiking in neurons
Kardos, J., Szilágyi, N., Juhász, G., Belhage, B. & Schousboe, Arne, 1998, In: NeuroReport. 9, 4, p. 721-4 4 p.Research output: Contribution to journal › Journal article › peer-review
- 1997
- Published
Characterization of glutamate-induced formation of N- acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons
Hansen, Harald S., Lauritzen, Lotte, Strand, A. M., Vinggaard, A. M., Frandsen, Aase & Schousboe, Arne, 1 Aug 1997, In: Journal of Neurochemistry. 69, 2, p. 753-761 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Characterization of microwell cultures of dissociated brain tissue for studies of cell-cell interactions
Maar, T. E., Rønn, L. C. B., Bock, E., Berezin, V., Moran, J., Pasantes-Moralez, H. & Schousboe, Arne, 1997, In: Journal of Neuroscience Research. 47, p. 163-172Research output: Contribution to journal › Journal article › peer-review
Comparison of the agonist binding site of homomeric, heteromeric, and chimeric GluR1(o) and GluR3(o) AMPA receptors
Banke, T. G., Schousboe, Arne, Pickering, D. S. & Pickering, D., 1997, In: Journal of Neuroscience Research. 49, 2, p. 176-85 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Expression of the GABA(A) receptor alpha6 subunit in cultured cerebellar granule cells is developmentally regulated by activation of GABA(A) receptors
Carlson, B. X., Belhage, B., Hansen, Gert Helge, Elster, L., Olsen, R. W. & Schousboe, Arne, 1997, In: Journal of Neuroscience Research. 50, 6, p. 1053-62 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures
Maar, T. E., Ellerbock, U., Bock, E., Nau, H., Schousboe, Arne & Berezin, V., 1997, In: Toxicology. 116, p. 159-168Research output: Contribution to journal › Journal article › peer-review
- Published
The First Immunoglodulin-like NCAM Domain is Invelved in both Double Reciprocal Interaction with the Second Ig-like NCAM Domain and in Heparin Binding
Kiselyov, V. V., Berezin, V., Maar, T., Soroka, V., Edvardsen, K., Schousboe, Arne & Bock, E., 1997, In: Journal of Biological Chemistry. 272, p. 10125-10134Research output: Contribution to journal › Journal article › peer-review
- 1995
- Published
Differential distribution of GABAA receptor subunits in soma and processes of cerebellar granule cells: effects of maturation and a GABA agonist
Elster, L., Hansen, Gert Helge, Belhage, B., Fritschy, J. M., Möhler, H. & Schousboe, Arne, 1995, In: International Journal of Developmental Neuroscience. 13, 5, p. 417-28 11 p.Research output: Contribution to journal › Journal article › peer-review
- 1994
- Published
GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects
Krogsgaard-Larsen, Povl, Frølund, Bente, Jørgensen, Flemming Steen & Schousboe, Arne, 1994, In: Journal of Medicinal Chemistry. 37, 16, p. 2489-505 17 p.Research output: Contribution to journal › Journal article › peer-review
- 1993
- Published
Characterization of NCAM diversity in cultured neurons
Gegelashvili, G., Andersson, A., Schousboe, Arne & Bock, E., 1993, In: FEBS Letters. 324, p. 337-340Research output: Contribution to journal › Journal article › peer-review
- Published
Cyclic AMP regulates NCAM expression and phosphorylation in cultures mouse astrocytes
Gegelashvili, G., Andersson, A., Schousboe, Arne & Bock, E., 1993, In: European Journal of Cell Biology. 62, p. 343-351Research output: Contribution to journal › Journal article › peer-review
- Published
Depletion of polyamines prevents the neurotrophic activity of the GABA-agonist THIP in cultured rat cerebellar granule cells
Abraham, J. H., Hansen, Gert Helge, Seiler, N. & Schousboe, Arne, 1993, In: Neurochemical Research. 18, 2, p. 153-8 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA
Belhage, B., Hansen, Gert Helge & Schousboe, Arne, 1993, In: Neuroscience. 54, 4, p. 1019-34 15 p.Research output: Contribution to journal › Journal article › peer-review
- 1992
- Published
Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes
Wahl, P., Nielsen, Birgitte, Krogsgaard-Larsen, Povl, Hansen, J. J., Schousboe, Arne & Miledi, R., Nov 1992, In: Journal of Neuroscience Research. 33, 3, p. 392-7 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
3H-D-aspartate release from cerebellar granule neurons is differentially regulated by glutamate- and K(+)-stimulation
Belhage, B., Rehder, V., Hansen, Gert Helge, Kater, S. B. & Schousboe, Arne, 1992, In: Journal of Neuroscience Research. 33, 3, p. 436-44 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
First direct electron microscopic visualization of a tight spatial coupling between GABAA-receptors and voltage-sensitive calcium channels
Hansen, Gert Helge, Belhage, B. & Schousboe, Arne, 1992, In: Neuroscience Letters. 137, 1, p. 14-8 4 p.Research output: Contribution to journal › Journal article › peer-review
- 1991
- Published
Effect of phenylsuccinate on potassium- and ischemia-induced release of glutamate in rat hippocampus monitored by microdialysis
Christensen, T., Bruhn, T., Diemer, N. H. & Schousboe, Arne, 16 Dec 1991, In: Neuroscience Letters. 134, 1, p. 71-74 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Effect of a GABA agonist on the expression and distribution of GABAA receptors in the plasma membrane of cultured cerebellar granule cells: an immunocytochemical study
Hansen, Gert Helge, Belhage, B. & Schousboe, Arne, 1991, In: Neuroscience Letters. 124, 2, p. 162-5 3 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Light and electron microscopic localization of GABAA-receptors on cultured cerebellar granule cells and astrocytes using immunohistochemical techniques
Hansen, Gert Helge, Hösli, E., Belhage, B., Schousboe, Arne & Hösli, L., 1991, In: Neurochemical Research. 16, 3, p. 341-6 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons
Ehrhart-Bornstein, M., Treiman, M., Hansen, Gert Helge, Schousboe, Arne, Thorn, N. A. & Frandsen, A., 1991, In: International Journal of Developmental Neuroscience. 9, 5, p. 463-71 8 p.Research output: Contribution to journal › Journal article › peer-review
- 1990
- Published
Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells
Belhage, B., Hansen, Gert Helge, Meier, E. & Schousboe, Arne, 1990, In: Journal of Neurochemistry. 55, 4, p. 1107-13 6 p.Research output: Contribution to journal › Journal article › peer-review
- Published
GABA agonist induced changes in ultrastructure and GABA receptor expression in cerebellar granule cells is linked to hyperpolarization of the neurons
Belhage, B., Hansen, Gert Helge & Schousboe, Arne, 1990, In: International Journal of Developmental Neuroscience. 8, 4, p. 473-9 7 p.Research output: Contribution to journal › Journal article › peer-review
- 1988
- Published
GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development
Belhage, B., Hansen, Gert Helge, Schousboe, Arne & Meier, E., 1988, In: International Journal of Developmental Neuroscience. 6, 2, p. 125-8 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Gamma-aminobutyric acid agonist-induced alterations in the ultrastructure of cultured cerebellar granule cells is restricted to early development
Hansen, Gert Helge, Belhage, B., Schousboe, Arne & Meier, E., 1988, In: Journal of Neurochemistry. 51, 1, p. 243-5 3 p.Research output: Contribution to journal › Journal article › peer-review
- 1987
- Published
Temporal development of GABA agonist induced alterations in ultrastructure and GABA receptor expression in cultured cerebellar granule cells
Hansen, Gert Helge, Belhage, B., Schousboe, Arne & Meier, E., 1987, In: International Journal of Developmental Neuroscience. 5, 3, p. 263-9 7 p.Research output: Contribution to journal › Journal article › peer-review
- 1985
- Published
Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids
Schousboe, Arne, Drejer, J., Hansen, Gert Helge & Meier, E., 1985, In: Developmental Neuroscience. 7, 5-6, p. 252-62 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
THE TROPHIC EFFECT OF GABA ON CEREBELLAR GRANULE CELLS IS MEDIATED BY GABA-RECEPTORS
Meier, E., Hansen, Gert Helge & Schousboe, Arne, 1985, In: International Journal of Developmental Neuroscience. 3, 4, p. 401-407 7 p.Research output: Contribution to journal › Journal article › peer-review
- 1984
- Published
GABA INFLUENCES THE ULTRASTRUCTURE COMPOSITION OF CEREBELLAR GRANULE CELLS DURING DEVELOPMENT IN CULTURE
Hansen, Gert Helge, Meier, E. & Schousboe, Arne, 1984, In: International Journal of Developmental Neuroscience. 2, 3, p. 247-257 11 p.Research output: Contribution to journal › Journal article › peer-review
ID: 1300836
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Astrocytic pyruvate carboxylation: Status after 35 years
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Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease
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The 13th International Conference on Brain Energy Metabolism: "How Metabolism Dictates Neurotransmission, Function and Behavior"
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