Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor


  1. 2018
  2. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P., Flannick, J., Grarup, Niels, Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, S., Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, Marianne, Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, Ruth, Gjesing, Anette Marianne Prior, Grarup, Niels, Hansen, Torben, Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, Allan René, Pedersen, Oluf Borbye, Pers, Tune H, drb459, drb459, Nordestgaard, Børge, Tybjærg-Hansen, Anne, Varbo, A., CHD Exome+ Consortium, C. E. C., EPIC-CVD Consortium, E. C., ExomeBP Consortium, E. C., Global Lipids Genetics Consortium, G. L. G. C., GoT2D Genes Consortium, G. G. C., EPIC-InterAct Consortium, E. C., INTERVAL Study, I. S., ReproGen Consortium, R. C., T2D-Genes Consortium, T. C., The MAGIC Investigators, T. M. I., Understanding Society Scientific Group, U. S. S. G., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    ABCA7 and risk of dementia and vascular disease in the Danish population

    Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals

    Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Advances in lipid-lowering therapy through gene-silencing technologies

    Nordestgaard, Børge, Nicholls, S. J., Langsted, A., Ray, K. K. & Tybjærg-Hansen, Anne, 2018, In: Nature Reviews Cardiology. 15, p. 261-272

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

    European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

    Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W. J., Small, A., Kwee, L. C., Dwivedi, O. P., Prasad, R. B., Bruse, S., Lopez, A. E., Penn, J., Marcketta, A., Leader, J. B., Still, C. D., Kirchner, H. L., Mirshahi, U. L., Wardeh, A. H., Hartle, C. M., Habegger, L., Fetterolf, S. N., Tusie-Luna, T., Morris, A. P., Holm, H., Steinthorsdottir, V., Sulem, P., Thorsteinsdottir, U., Rotter, J. I., Chuang, L. M., Damrauer, S., Birtwell, D., Brummett, C. M., Khera, A. V., Natarajan, P., Orho-Melander, M., Flannick, J., Lotta, L. A., Willer, C. J., Holmen, O. L., Ritchie, M. D., Ledbetter, D. H., Murphy, A. J., Borecki, I. B., Reid, J. G., Overton, J. D., Hansson, O., Groop, L., Shah, S. H., Kraus, W. E., Rader, D. J., Chen, Y. D. I., Hveem, K., Wareham, N. J., Kathiresan, S., Melander, O., Stefansson, K., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Abecasis, G. R., Altshuler, D., Florez, J. C., Boehnke, M., McCarthy, M. I., Yancopoulos, G. D., Carey, D. J., Shuldiner, A. R., Baras, A., Dewey, F. E. & Gromada, J., 2018, In: Nature Communications. 9, 1, 2252.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease

    Qayyum, F., Lauridsen, B. K., Frikke-Schmidt, Ruth, Kofoed, K. F., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 22, p. 2106-2116 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease: Mendelian randomization and meta-analysis of 279 013 individuals

    Lauridsen, B. K., Stender, S., zwp671, zwp671, Kofoed, K. F., Køber, Lars Valeur, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 5, p. 385-393 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans

    Oldoni, F., van Capelleveen, J. C., Dalila, N., Wolters, J. C., Heeren, J., Sinke, R. J., Hui, D. Y., Dallinga-Thie, G. M., Frikke-Schmidt, Ruth, Hovingh, K. G., van de Sluis, B., Tybjærg-Hansen, Anne & Kuivenhoven, J. A., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 7, p. 1440-1453 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

    Vallejo-Vaz, A. J., Marco, M. D., Stevens, C. A. T., Akram, A., Freiberger, T., Hovingh, G. K., Kastelein, J. J. P., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar Salinas, C. A., Al-Khnifsawi, M., Alkindi, F. A., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A., Ashavaid, T. F., Binder, C. J., Bogsrud, M. P., Bourbon, M., Bruckert, E., Chlebus, K., Corral, P., Descamps, O., Durst, R., Ezhov, M., Fras, Z., Genest, J., Groselj, U., Harada-Shiba, M., Kayikçioglu, M., Lalic, K., Lam, C. S. P., Latkovskis, G., Laufs, U., Liberopoulos, E., Lin, J., Maher, V., Majano, N., Marais, D., März, W., Mirrakhimov, E., Miserez, A. R., Mitchenko, O., Nawawi, H. M., Nordestgaard, Børge, Paragh, G., Petrulioniene, Z., Pojskic, B., Postadzhiyan, A., Reda, A., Reiner, Ž., Sadoh, W. E., Sahebkar, A., Shehab, A., Shek, A. B., Stoll, M., Su, T. C., Subramaniam, T., Susekov, A. V., Symeonides, P., Tilney, M., Tomlinson, B., Truong, T. H., Tselepis, A. D., Tybjærg-Hansen, Anne, Vázquez-Cárdenas, A., Viigimaa, M., Vohnout, B., Widén, E., Yamashita, S., Banach, M., Gaita, D., Jiang, L., Nilsson, L., Santos, L. E., Schunkert, H., Tokgözoğlu, L., Car, J., Catapano, A. L., Ray, K. K., Schreier, L., Pang, J., Dieplinger, H., Hanauer-Mader, G., Desutter, J., Langlois, M., Mertens, A., Rietzschel, E., Wallemacq, C., Isakovic, D., Dzankovic, A. M., Obralija, J., Pojskic, L., Sisic, I., Stimjanin, E., Torlak, V. A., Jannes, C. E., Krieger, J. E., Pereira, A. C., Ruel, I., Asenjo, S., Cuevas, A., Pećin, I., Miltiadous, G., Panayiotou, A. G., Vrablik, M., Benn, Marianne, Heinsar, S., Béliard, S., Gouni-Berthold, I., Hengstenberg, W., Julius, U., Kassner, U., Klose, G., König, C., König, W., Otte, B., Parhofer, K., Schatz, U., Schmidt, N., Steinhagen-Thiessen, E., Vogt, A., Antza, C., Athyros, V., Bilianou, E., Boufidou, A., Chrousos, G., Elisaf, M., Garoufi, A., Katsiki, N., Kolovou, G., Kotsis, V., Rallidis, L., Rizos, C., Skalidis, E., Skoumas, I., Tziomalos, K., Shawney, J. P. S., Abbaszadegan, M. R., Aminzadeh, M., Hosseini, S., Mobini, M., Vakili, R., Zaeri, H., Agar, R., Boran, G., Colwell, N., Crowley, V., Durkin, M., Griffin, D., Kelly, M., Rakovac-Tisdall, A., Bitzur, R., Cohen, H., Eliav, O., Ellis, A., Gavish, D., Harats, D., Henkin, Y., Knobler, H., Leavit, L., Leitersdorf, E., Schurr, D., Shpitzen, S., Szalat, A., Arca, M., Averna, M., Bertolini, S., Calandra, S., Tarugi, P., Erglis, A., Gilis, D., Nesterovics, G., Saripo, V., Upena-Roze, A., Elbitar, S., Jambart, S., Khoury, P. E., Gargalskaite, U., Kutkiene, S., Al-Khateeb, A., An, C. Y., Ismail, Z., Kasim, S., Ibrahim, K. S., Radzi, A. B. M., Kasim, N. A., Nor, N. S. M., Ramli, A. S., Razak, S. A., Muid, S., Rosman, A., Sanusi, A. R., Razman, A. Z., Nazli, S. A., Kek, T. L., Azzopardi, C., Aguilar Salinas, C. A., Galán, G., Rubinstein, A., Magaña-Torres, M. T., Martagon, A., Mehta, R., Wittekoek, M. E., Isara, A. R., Obaseki, D. E., Ohenhen, O. A., Holven, K. B., Gruchała, M., Baranowska, M., Borowiec-Wolny, J., Gilis-Malinowska, N., Michalska-Grzonkowska, A., Pajkowski, M., Parczewska, A., Romanowska-Kocejko, M., Stróżyk, A., Żarczyńska-Buchowiecka, M., Kleinschmidt, M., Alves, A. C., Medeiros, A. M., Ershova, A., Korneva, V., Kuznetsova, T., Malyshev, P., Meshkov, A., Rozhkova, T., Popovic, L., Lukac, S. S., Stosic, L., Rasulic, I., Lalic, N. M., Chua, T. S. J., Ting, S. P. L., Raslova, K., Battelino, T., Cevc, M., Jug, B., Kovac, J., Podkrajsek, K. T., Sustar, U., Trontelj, K. J., Marais, D., Isla, L. P. D., Martin, F. J., Charng, M. J., Chen, P. L., Kayikçioglu, M., Dell’oca, N., Fernández, G., Ressia, A., Reyes, X., Zelarayan, M., Alieva, R. B., Hoshimov, S. U., Nizamov, U. I., Kurbanov, R. D., Lima-Martínez, M. M., Nguyen, M. N. T., Do, D. L., Kim, N. T., Le, T. T. & Le, H. A., 2018, In: Atherosclerosis. 277, p. 234-255 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride

    Stender, S., Smagris, E., Lauridsen, B. K., Kofoed, K. F., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Pennacchio, L. A., Dickel, D. E., Cohen, J. C. & Hobbs, H. H., 2018, In: Hepatology. 67, 6, p. 2182-2195 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Response to: liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease

    Stender, S. & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 36, p. 3399

    Research output: Contribution to journalComment/debateResearchpeer-review

  17. Published

    U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies

    Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 14, p. 1181-1190 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 924951