Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor

Member of:

  • Clinical Biochemistry


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  1. Published

    Major lipids, apolipoproteins and risk of vascular disease.

    (Tybjaerg-Hansen, A. ). T. E. R. F. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: JAMA - Journal of the American Medical Association. 302, p. 1993-2000 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality

    (Tybjaerg-Hansen, A. ). T. F. S. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: JAMA - Journal of the American Medical Association. 302, 4, p. 412-423 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Measures to assess the prognostic ability of the stratified Cox proportional hazards model

    (Tybjaerg-Hansen, A. ). T. F. S. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: Statistics in Medicine. 28, 3, p. 389-411 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    BODY MASS INDEX AND MORTALITY OVER 3 DECADES

    Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, Sep 2016, In: Atherosclerosis. 252, p. E222-E222 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  5. Published

    Change in Body Mass Index Associated With Lowest Mortality in Denmark, 1976-2013

    Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, 10 May 2016, In: JAMA - Journal of the American Medical Association. 315, 18, p. 1989-1996 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    C-reactive protein and the risk of cancer: a mendelian randomization study

    Allin, K. H., Nordestgaard, Børge, Zacho, J., Tybjærg-Hansen, Anne & Bojesen, Stig Egil, 2010, In: National Cancer Institute. Journal (Print). 102, 3, p. 202-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease

    Argraves, K. M., Sethi, A. A., Gazzolo, P. J., Wilkerson, B. A., Remaley, A. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Yeatts, S. D., Nicholas, K. S., Barth, J. L. & Argraves, W. S., 2011, In: Lipids in Health and Disease. 10, p. 70

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Surfactant Protein-B 121ins2 Heterozygosity, Reduced Pulmonary Function, and Chronic Obstructive Pulmonary Disease in Smokers

    Baekvad-Hansen, M., Dahl, Morten, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 1 Jan 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Two novel mutations in surfactant protein-C, lung function and obstructive lung disease

    Baekvad-Hansen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Dahl, M., 2010, In: Respiratory Medicine. 104, 3, p. 418-425

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Dynamic and Multifaceted Nature of Cardiovascular Disease and Using Genetic Testing to Inform Clinical Care: An International Perspective

    Baudhuin, L. M., De Backer, J., Ingles, J., Milewicz, D. M. & Tybjærg-Hansen, Anne, 2021, In: Clinical Chemistry. 67, 1, p. 33-40 8 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  11. Published

    Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study

    Benfield, T., Ejrnæs, K., Juul, K., Ostergaard, C., Helweg-Larsen, J., Weis, N., Munthe-Fog, L., Kronborg, G., Andersen, M. R., Tybjærg-Hansen, A., Nordestgaard, B. G., Garred, P., Benfield, T., Ejrnaes, K., Juul, K., Andersen, C. Ø., Helweg-Larsen, J., Weis, N. M., Munthe-Fog, L., Kronborg, G. & 4 others, Andersen, M. R., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Garred, Peter, 1 Jan 2010, In: Critical Care (Online Edition). 14, 2, p. R28

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Influence of the factor V Leiden mutation on infectious disease susceptibility and outcome: a population-based study

    Benfield, Thomas, Dahl, M., Nordestgaard, B. G., Tybjærg-Hansen, Anne & Dahl, M., 15 Nov 2005, In: Journal of Infectious Diseases. 192, 10, p. 1851-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Common and Rare Alleles in Apolipoprotein B Contribute to Plasma Levels of LDL Cholesterol in the General Population.

    Benn, M., Stene, M., Nordestgaard, B., Jensen, G. B., Steffensen, R., Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1038-45

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Improving prediction of ischemic cardiovascular disease in the general population using apolipoprotein B: the Copenhagen City Heart Study

    Benn, M., Nordestgaard, B., Jensen, G. B., Tybjaerg-Hansen, A., Tybjærg-Hansen, Anne, Benn, M. & Nordestgaard, Børge, 2007, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 3, p. 661-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Common and rare alleles in apolipoprotein B contribute to plasma levels of low-density lipoprotein cholesterol in the general population

    Benn, Marianne, Stene, M. C. A., Nordestgaard, Børge, Jensen, G. B., Steffensen, R. & Tybjærg-Hansen, Anne, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1038-1045 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Impact of glucose on risk of dementia: Mendelian randomisation studies in 115,875 individuals

    Benn, Marianne, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: Diabetologia. 63, p. 1151-1161

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study

    Benn, Marianne, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 24 Apr 2017, In: B M J. 357, 11 p., j1648.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study

    Benn, M., Tybjærg-Hansen, Anne, McCarthy, M. I., Jensen, G. B., Grande, P. & Nordestgaard, Børge, 2012, In: Journal of the American College of Cardiology. 59, 25, p. 2356-65 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mitochondrial haplogroups: ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population

    Benn, M., Schwartz, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2008, In: Circulation. 117, 19, p. 2492-501 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Polymorphism in APOB associated with increased low-density lipoprotein levels in both genders in the general population

    Benn, M., Nordestgaard, Børge, Jensen, J. S., Grande, P., Sillesen, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 10, p. 5797-803 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis

    Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    High body mass index and cancer risk

    Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study

    Benn, Marianne, Tybjærg-Hansen, Anne, Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Benn, M., 16 Mar 2011, In: National Cancer Institute. Journal (Print). 103, 6, p. 508-19 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 3956-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals

    Benn, Marianne, Marott, S. C. W., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: Cardiovascular Research. 118, 18, p. 3576-3585 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor

    Benn, M., Nordestgaard, Børge, Jensen, J. S., Nilausen, K. S., Meinertz, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Biological Chemistry. 280, 22, p. 21052-60 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality

    Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3102-3114

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Polymorphisms in apolipoprotein B and risk of ischemic stroke

    Benn, M., Nordestgaard, Børge, Jensen, J. S. & Tybjærg-Hansen, Anne, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 9, p. 3611-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women

    Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses

    Benn, Marianne, Nordestgaard, Børge, Grande, P., Schnohr, P., Tybjærg-Hansen, Anne & Benn, M., 22 Jun 2010, In: Journal of the American College of Cardiology. 55, 25, p. 2833-42 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    European Lipoprotein Club: report of the 31st ELC Annual Conference, Tutzing, 8-11 September 2008

    Bernini, F., Freeman, D., Groen, A., Heeren, J., Kalopissis, A., Kronenberg, F., Lindstedt, K., Parini, P., Schuster, G., Tybjærg-Hansen, Anne, Dij, K. W. V. & Eckardstein, A. V., 2009, In: Atherosclerosis. 205, 1, p. 41-47 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010

    Bernini, F., Fisher, R., Freeman, D., Groen, A., Kalopissis, A., Malle, E., Mulder, M., Niemeier, A., Parini, P., Tybjærg-Hansen, Anne & von Eckardstein, A., 2011, In: Atherosclerosis. 215, 1, p. 249-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011

    Bernini, F., Costet, P., Ehrenborg, E., Fisher, R., Fielding, B., Freeman, D., Groen, A., Malle, E., Mulder, M., Niemeier, A., Tybjærg-Hansen, Anne & von Eckardstein, A., 2012, In: Atherosclerosis. 221, p. 287-93

    Research output: Contribution to journal › Journal article › Research

  35. Published

    Common genetic variation in mc4r does not affect atherosclerotic plaque phenotypes and cardiovascular disease outcomes

    Blauw, L. L., Noordam, R., van der Laan, S. W., Trompet, S., Kooijman, S., van Heemst, D., Jukema, J. W., van Setten, J., de Borst, G. J., Tybjærg-Hansen, Anne, Pasterkamp, G., Berbée, J. F. P. & Rensen, P. C. N., 2021, In: Journal of Clinical Medicine. 10, 5, 12 p., 932.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm

    Bottolo, L., Chadeau-Hyam, M., Hastie, D. I., Zeller, T., Liquet, B., Newcombe, P., Yengo, L., Wild, P. S., Schillert, A., Ziegler, A., Nielsen, S. F., Butterworth, A. S., Ho, W. K., Castagné, R., Munzel, T., Tregouet, D., Falchi, M., Cambien, F., Nordestgaard, B., Fumeron, F. & 7 others, Tybjærg-Hansen, Anne, Froguel, P., Danesh, J., Petretto, E., Blankenberg, S., Tiret, L. & Richardson, S., 2013, In: P L o S Genetics. 9, 8, p. 1-17 17 p., e1003657.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

    Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., Gretarsdottir, S., Badger, S. A., Bradley, D. T., Burnand, K., Child, A. H., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, S., Johnson, A., Sohrabi, S., Smith, A., Thompson, M. M. & 31 others, van Bockxmeer, F. M., Waltham, M., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A. W., Wijmenga, C., de Graaf, J., Kiemeney, L. A., Assimes, T. L., McPherson, R., Folkersen, L. W., Franco-Cereceda, A., Palmen, J., Smith, F. A., Sylvius, N., Wild, J. B., Refstrup, M., Edkins, S., Gwilliam, R., Hunt, S. E., Potter, S., Lindholt, J. S., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Hughes, A. E., Golledge, J., Norman, P. E., van Rij, A. & CARDIoGRAM Consortium, C. C., 2011, In: American Journal of Human Genetics. 89, 5, p. 619-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Genetic variants in SUSD2 are associated with the risk of ischemic heart disease

    Bruikman, C. S., Dalila, N., van Capelleveen, J. C., Kroon, J., Peter, J., Havik, S. R., Willems, M., Huisman, L. C., de Boer, O. J., Hovingh, G. K., Tybjærg-Hansen, Anne & Dallinga-Thie, G. M., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 470-481

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    25-hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants

    Brøndum-Jacobsen, P., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: Journal of Thrombosis and Haemostasis. 11, 3, p. 423-431

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Genomet i kardiologien

    Bundgård, Henning, Diness, Birgitte Rode, Tfelt-Hansen, Jacob, Henriksen, F. L., Eschen, O., Skovby, F., Havndrup, O., Jensen, H. K. & Tybjærg-Hansen, Anne, 2014, In: Ugeskrift for Laeger. 176, 46, 5 p., V06140376.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

    European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables

    Burgess, S., Thompson, S. G., Thompson, G., Andrews, G., Samani, N. J., Hall-Andersen, A. M., Whincup, P., Morris, R., Lawlor, D. A., Davey Smith, G., Timpson, N., Ebrahim, S., Ben-Shlomo, Y., Brown, M., Ricketts, S., Sandhu, M., Reiner, A., Psaty, B., Lange, L., Cushman, M. & 31 others, Hung, J., Thompson, P., Beilby, J., Warrington, N., Palmer, L. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Zacho, J., Wu, C., Lowe, G., Tzoulaki, I., Perera, M. K., Yamamoto, J. F., Chiodini, B., Franzosi, M., Hankey, G. J., Jamrozik, K., Palmer, L., Rimm, E., Pai, J., Heckbert, S., Bis, J., Anand, S., Engert, J., Collins, R., Clarke, R., Melander, O., Berglund, G., Ladenvall, P., Johansson, L. & CRP CHD Genetics Collaboration, C. C. G. C., 30 May 2010, In: Statistics in Medicine. 29, 12, p. 1298-311 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Surfactant protein-B 121ins2 heterozygosity, reduced pulmonary function, and chronic obstructive pulmonary disease in smokers

    Bækvad-Hansen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Jan 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Surfactant Protein-B 121ins2 Heterozygosity, Reduced Pulmonary Function and COPD in Smokers

    Bækvad-Hansen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study

    Carter, A. R., Borges, M., Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Nordestgaard, Børge & Lawlor, D. A., 2019, In: JAMA Network Open. 2, 3, 14 p., e190305.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

    Chapman, M. J., Ginsberg, H. N., Amarenco, P., Andreotti, F., Borén, J., Catapano, A. L., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik, P., Masana, L., Nordestgaard, Børge, Ray, K. K., Reiner, Z., Taskinen, M., Tokgözoglu, L., Tybjærg-Hansen, Anne, Watts, G. F. & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 2011, In: European Heart Journal (English Edition). 32, 11, p. 1345-61 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy

    Christensen, Alex Hørby, Andersen, C. B., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Clinical Genetics. 80, 3, p. 256-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Wide spectrum of desmosomal mutations in Danish patients with arrhythmogenic right ventricular cardiomyopathy

    Christensen, A. H., Benn, M., Bundgaard, H., Tybjærg-Hansen, Anne, Haunsø, Stig & Svendsen, Jesper Hastrup, Nov 2010, In: Journal of Medical Genetics. 47, 11, p. 736-44 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients - disease - causing or innocent bystanders?

    Christensen, A. H., Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, J. H., 2009, In: Cardiology. 115, 2, p. 148-154 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?

    Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S., Svendsen, Jesper Hastrup, Christensen, A. H., Benn, M., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 1 Jan 2010, In: Cardiology. 115, 2, p. 148-54 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 924951