Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor


  1. 2021
  2. Published

    Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

    EADB contributors, E. C., The GR@ACE study group, T. G. S. G., DEGESCO consortium, D. C., IGAP (ADGC, CHARGE, EADI, GERAD), I. (. C. E. G. & PGC-ALZ consortia, P. C., Dec 2021, In: Nature Communications. 12, 1, 16 p., 3417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Elevated Apolipoprotein A1 and HDL Cholesterol Associated with Age-related Macular Degeneration: 2 Population Cohorts

    Nordestgaard, Liv Tybjærg, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 16 Jun 2021, In: The Journal of clinical endocrinology and metabolism. 106, 7, p. e2749-e2758 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Comparison of sixteen serological SARS-CoV-2 immunoassays in sixteen clinical laboratories

    Harritshøj, L. H., Gybel-Brask, M., Afzal, Shoaib, Kamstrup, P. R., Jørgensen, C. S., Thomsen, M. K., Hilsted, Linda, Friis-Hansen, L., Szecsi, P. B., Pedersen, L., Nielsen, L., Hansen, Cecilie Bo, Garred, Peter, Korsholm, T., Mikkelsen, S., Nielsen, K. O., Møller, B. K., Tybjærg-Hansen, Anne, Iversen, Kasper, Nielsen, Pernille Brok, Hasselbalch, Rasmus Bo, Fogh, K., Norsk, Jakob Boesgaard, Kristensen, Jonas Henrik, Schønning, K., Kirkby, N. S., Nielsen, A. C. Y., Landsy, L. H., Loftager, M., Holm, D. K., Nilsson, A. C., Sækmose, S. G., Grum-Schwensen, B., Aagaard, B., Jensen, T. G., Nielsen, D. M., Ullum, Henrik & Dessau, R. B. C., 11 Feb 2021, In: Journal of Clinical Microbiology. 59, 5, e02596-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Association of Low Plasma Transthyretin Concentration with Risk of Heart Failure in the General Population

    Greve, A. M., Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2021, In: JAMA Cardiology. 6, 3, p. 258-266

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Accepted/In press

    Genetic Variants Associated With Increased Plasma Levels of Triglycerides, via Effects on the Lipoprotein Lipase Pathway, Increase Risk of Acute Pancreatitis

    Hansen, S. E. J., Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, (Accepted/In press) In: Clinical Gastroenterology and Hepatology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis

    Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis

    Trinder, M., Wang, Y., Madsen, C. M., Ponomarev, T., Bohunek, L., Daisley, B. A., Kong, H. J., Blauw, L. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Wurfel, M. M., Russell, J. A., Walley, K. R., Rensen, P. C. N., Boyd, J. H. & Brunham, L. R., 2021, In: Circulation. 143, 9, p. 921–934

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Plasma Concentrations of Magnesium and Risk of Dementia: A General Population Study of 102 648 Individuals

    Thomassen, J. Q., Tolstrup, Janne Schurmann, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 6, p. 899-911 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Polygenic risk scores: how much do they add?

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: Current Opinion in Lipidology. 32, 3, p. 157-162 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe

    Hageman, S., Pennells, L., Ojeda, F., Kaptoge, S., Kuulasmaa, K., de Vries, T., Xu, Z., Kee, F., Chung, R., Wood, A., McEvoy, J. W., Veronesi, G., Bolton, T., Dendale, P., Ference, B. A., Halle, M., Timmis, A., Vardas, P., Danesh, J., Graham, I., Salomaa, V., Visseren, F., De Bacquer, D., Blankenberg, S., Dorresteijn, J., Di Angelantonio, E., Achenbach, S., Aleksandrova, K., Amiano, P., Amouyel, P., Andersson, J., Bakker, S. J. L., Costa, R. B. D. P., Beulens, J. W. J., Blaha, M., Bobak, M., Boer, J. M. A., Bonet, C., Bonnet, F., Boutron-Ruault, M., Braaten, T., Brenner, H., Brunner, F., Brunner, E. J., Brunstrom, M., Jørgensen, T., Linneberg, Allan René, Overvad, K., Tjønneland, Anne, Tybjærg-Hansen, Anne, SCORE2 Working Grp, S. W. G. & ESC Cardiovasc Risk Collaboration, E. C. R. C., 2021, In: European Heart Journal. 42, 25, p. 2439-2454 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Targeting IL-6 in patients at high cardiovascular risk

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: The Lancet. 397, 10289, p. 2025-2027 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  13. Published

    The Dynamic and Multifaceted Nature of Cardiovascular Disease and Using Genetic Testing to Inform Clinical Care: An International Perspective

    Baudhuin, L. M., De Backer, J., Ingles, J., Milewicz, D. M. & Tybjærg-Hansen, Anne, 2021, In: Clinical Chemistry. 67, 1, p. 33-40 8 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  14. Published

    Triglycerides as a Shared Risk Factor between Dementia and Atherosclerotic Cardiovascular Disease: A Study of 125 727 Individuals

    Nordestgaard, Liv Tybjærg, Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 1, p. 245-255 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2020
  16. Published

    Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study

    Emanuelsson, F., Marott, S., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, Apr 2020, In: Diabetes Care. 43, 4, p. 894-902 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    APOE and dementia – resequencing and genotyping in 105,597 individuals

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2020, In: Alzheimer's and Dementia. 16, 12, p. 1624-1637 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor

    Rimbert, A., Dalila, N., Wolters, J. C., Huijkman, N., Smit, M., Kloosterhuis, N., Riemsma, M., Van Der Veen, Y., Singla, A., Van Dijk, F., Frikke-Schmidt, Ruth, Burstein, E., Tybjærg-Hansen, Anne, Van De Sluis, B. & Kuivenhoven, J. A., 2020, In: European Heart Journal. 41, 9, p. 1040-1053 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Apolipoprotein M and Risk of Type 2 Diabetes

    Hajny, S., Christoffersen, M., Dalila, N., Nielsen, L. B., Tybjærg-Hansen, Anne & Christoffersen, Christina, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 9, p. 3046-3057

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Autosomal recessive hypercholesterolemia in a kindred of Syrian ancestry

    Martinsen, M. H., Klausen, I. C., Tybjærg-Hansen, Anne & Hedegaard, B. S., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 419-424

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Coffee intake protects against symptomatic gallstone disease in the general population: a Mendelian randomization study

    Nordestgaard, A. T., Stender, S., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2020, In: Journal of Internal Medicine. 287, 1, p. 42-53

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population

    Gellert-Kristensen, H., Richardson, T. G., Davey Smith, G., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Hepatology. 72, 3, p. 845-856

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genetic Variation at PPP1R3B Increases Hepatic CT Attenuation and Interacts With Prandial Status on Plasma Glucose

    Seidelin, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Journal of Clinical Endrocrinology and Metabolism. 105, 6, p. 1963–1972

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Genetic variants in SUSD2 are associated with the risk of ischemic heart disease

    Bruikman, C. S., Dalila, N., van Capelleveen, J. C., Kroon, J., Peter, J., Havik, S. R., Willems, M., Huisman, L. C., de Boer, O. J., Hovingh, G. K., Tybjærg-Hansen, Anne & Dallinga-Thie, G. M., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 470-481

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase–Lowering Effect of a HSD17B13 Variant

    Gellert-Kristensen, H., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Hepatology. 71, 1, p. 56-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention

    Juul Rasmussen, I., Rasmussen, K. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: European Heart Journal. 41, 41, p. 4024-4033 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Impact of glucose on risk of dementia: Mendelian randomisation studies in 115,875 individuals

    Benn, Marianne, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: Diabetologia. 63, p. 1151-1161

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Repositioning of the global epicentre of non-optimal cholesterol

    NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Taddei, C., Zhou, B., Bixby, H., Nordestgaard, Børge, Benn, Marianne, Linneberg, Allan René, Tybjærg-Hansen, Anne, Cisneros, J. Z., Gregg, E. W., Ezzati, M. & Sørensen, Thorkild I.A., 2020, In: Nature. 582, 7810, p. 73-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The European heart journal: Leading the fight to reduce the global burden of cardiovascular disease

    Crea, F., Badimon, L., Berry, C., de Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C., Tybjærg-Hansen, Anne & EHJ Editorial Board, E. E. B., 2020, In: European Heart Journal. 41, 33, p. 3113-3116 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  30. 2019
  31. Published

    Plasma levels of apolipoprotein E, APOE genotype, and all-cause and cause-specific mortality in 105949 individuals from a white general population cohort

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 1 Sep 2019, In: European Heart Journal. 40, 33, p. 2813-2824 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study

    Emanuelsson, F., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Sep 2019, In: Journal of the American College of Cardiology. 74, 11, p. 1465-1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Identification and Replication of Six Loci Associated With Gallstone Disease

    Gellert-Kristensen, H., Dalila, N., Fallgaard Nielsen, S., Grønne Nordestgaard, B., Tybjærg-Hansen, Anne & Stender, S., Aug 2019, In: Hepatology. 70, 2, p. 597-609 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality

    Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3102-3114

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Blood–brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals

    Juul Rasmussen, I., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2019, In: European Journal of Epidemiology. 34, 6, p. 579-590 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Causal Associations in Type 2 Diabetes Development

    Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 4, p. 1313-1324

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study

    Carter, A. R., Borges, M., Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Nordestgaard, Børge & Lawlor, D. A., 2019, In: JAMA Network Open. 2, 3, 14 p., e190305.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies

    Pennells, L., Kaptoge, S., Wood, A., Sweeting, M., Zhao, X., White, I., Burgess, S., Willeit, P., Bolton, T., Moons, K. G. M., van der Schouw, Y. T., Selmer, R., Khaw, K., Gudnason, V., Assmann, G., Amouyel, P., Salomaa, V., Kivimaki, M., Nordestgaard, Børge, Blaha, M. J., Kuller, L. H., Brenner, H., Gillum, R. F., Meisinger, C., Ford, I., Knuiman, M. W., Rosengren, A., Lawlor, D. A., Volzke, H., Cooper, C., Ibanez, A. M., Casiglia, E., Kauhanen, J., Cooper, J. A., Rodriguez, B., Sundstrom, J., Barrett-Connor, E., Dankner, R., Nietert, P. J., Davidson, K. W., Wallace, R. B., Blazer, D. G., Bjorkelund, C., Donfrancesco, C., Krumholz, H. M., Nissinen, A., Davis, B. R., Coady, S., Whincup, P. H., Jørgensen, T., Ducimetiere, P., Trevisan, M., Engstrom, G., Crespo, C. J., Meade, T., Visser, M., Kromhout, D., Kiechl, S., Daimon, M., Price, J. F., de la Camara, A. G., Jukema, J. W., Lamarche, B., Onat, A., Simons, L. A., Kavousi, M., Ben-Shlomo, Y., Gallacher, J., Dekker, J. M., Arima, H., Shara, N., Tipping, R., Roussel, R., Brunner, E. J., Koenig, W., Sakurai, M., Pavlovic, J., Gansevoort, R. T., Nagel, D., Goldbourt, U., Barr, E. L. M., Palmieri, L., Njølstad, I., Sato, S., Verschuren, W. M. M., Varghese, C. V., Graham, I., Onuma, O., Greenland, P., Woodward, M., Ezzati, M., Psaty, B. M., Sattar, N., Jackson, R., Ridker, P. M., Cook, N., D'Agostino, R. B. ,. S., Thompson, S. G., Danesh, J., Di Angelantonio, E., Tipping, R. W., Simpson, L. M., Pressel, S. L., Couper, D. J., Nambi, V., Matsushita, K., Folsom, A. R., Shaw, J. E., Magliano, D. J., Zimmet, P. Z., Knuiman, M. W., Whincup, P. H., Wannamethee, S. G., Willeit, J., Santer, P., Egger, G., Casas, J. P., Amuzu, A., Ben-Shlomo, Y., Gallacher, J., Tikhonoff, V., Casiglia, E., Sutherland, S. E., Nietert, P. J., Cushman, M., Psaty, B. M., Sogaard, A. J., Haheim, L. L., Ariansen, I., Tybjærg-Hansen, Anne, Jensen, G. B., Schnohr, P., Giampaoli, S., Vanuzzo, D., Panico, S., Palmieri, L., Balkau, B., Bonnet, F., Marre, M., de la Camara, A. G., Herrera, M. A. R., Friedlander, Y., McCallum, J., McLachlan, S., Guralnik, J., Phillips, C. L., Guralnik, J., Khaw, K., Wareham, N., Schottker, B., Saum, K., Holleczek, B., Nissinen, A., Tolonen, H., Giampaoli, S., Donfrancesco, C., Jousilahti, P., Harald, K., D'Agostino, R. B. ,. S., Massaro, J. M., Pencina, M., Vasan, R., Massaro, J. M., Pencina, M., Vasan, R., Kayama, T., Kato, T., Oizumi, T., Jespersen, J., Møller, L., Bladbjerg, E. M., Chetrit, A., Rosengren, A., Wilhelmsen, L., Bjorkelund, C., Lissner, L., Nagel, D., Dennison, E., Kiyohara, Y., Ninomiya, T., Doi, Y., Rodriguez, B., Nijpels, G., Stehouwer, C. D. A., Sato, S., Kazumasa, Y., Iso, H., Goldbourt, U., Salomaa, V., Vartiainen, E., Kurl, S., Tuomainen, T., Salonen, J. T., Visser, M., Deeg, D. J. H., Meade, T., Nilsson, P. M., Hedblad, B., Melander, O., De Boer, I. H., DeFilippis, A. P., Verschuren, W. M. M., Sattar, N., Watt, G., Meisinger, C., Koenig, W., Verschuren, M., Rosengren, A., Kuller, L. H., Tverdal, A., Gillum, R. F., Cooper, J. A., Kirkland, S., Shimbo, D., Shaffer, J., Sato, S., Kazumasa, Y., Iso, H., Ducimetiere, P., Bakker, S. J. L., van der Harst, P., Hillege, H. L., Crespo, C. J., Amouyel, P., Dallongeville, J., Assmann, G., Schulte, H., Trompet, S., Smit, R. A. J., Stott, D. J., van der Schouw, Y. T., Despres, J., Cantin, B., Dagenais, G. R., Laughlin, G., Wingard, D., Khaw, K., Trevisan, M., Aspelund, T., Eiriksdottir, G., Gudmundsson, E. F., Ikram, A., van Rooij, F. J. A., Franco, O. H., Rueda-Ochoa, O. L., Muka, T., Glisic, M., Tunstall-Pedoe, H., Volzke, H., Howard, B. V., Zhang, Y., Jolly, S., Gallacher, J., Davey-Smith, G., Can, G., Yuksel, H., Nakagawa, H., Morikawa, Y., Miura, K., Njølstad, I., Ingelsson, M., Giedraitis, V., Ridker, P. M., Gaziano, J. M., Kivimaki, M., Shipley, M., Brunner, E. J., Arndt, V., Brenner, H., Cook, N., Ridker, P. M., Ford, I., Sattar, N., Ibanez, A. M. & Geleijnse, J. M., 2019, In: European Heart Journal. 40, 7, p. 621-631 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text

    Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 498-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review

    Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 515-537

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement

    Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 538-540

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Residual vascular risk in diabetes: Will the SPPARM alpha concept hold the key?

    Fruchart, J. C., Santos, R. D., Yamashita, S., Libby, P., International Atherosclerosis Society/R3i Foundation Consensus Panel, I. A. S. F. C. P., Fruchart, J., Santos, R. D., Yamashita, S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Watts, G. F., Yokote, K. & Zambon, A., 2019, In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 13, 4, p. 2723-2725

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

    Yang, Y., van der Klaauw, A. A., Zhu, L., Cacciottolo, T. M., He, Y., Stadler, L. K. J., Wang, C., Xu, P., Saito, K., Hinton, A., Yan, X., Keogh, J. M., Henning, E., Banton, M. C., Hendricks, A. E., Bochukova, E. G., Mistry, V., Lawler, K. L., Liao, L., Xu, J., O'Rahilly, S., Tong, Q., Barroso, I., O'Malley, B. W., Farooqi, I. S., Xu, Y., Balasubramanian, S., Clapham, P., Coates, G., Cox, T., Daly, A., Danecek, P., Du, Y., Durbin, R., Edkins, S., Ellis, P., Flicek, P., Guo, X., Guo, X., Huang, L., Jackson, D. K., Joyce, C., Keane, T., Kolb-Kokocinski, A., Langford, C., Li, Y., Liang, J., Lin, H., Liu, R., Maslen, J., McCarthy, S., Muddyman, D., Quail, M. A., Stalker, J., Sun, J., Tian, J., Wang, G., Wang, J., Wang, Y., Wong, K., Zhang, P., Birney, E., Boustred, C., Brion, M., Chen, L., Clement, G., Danecek, P., Smith, G. D., Day, I. N. M., Day-Williams, A., Down, T., Dunham, I., Durbin, R., Evans, D. M., Fatemifar, G., Gaunt, T. R., Geihs, M., Greenwood, C. M. T., Hart, D., Howie, B., Huang, J., Hubbard, T., Hysi, P., Iotchkova, V., Jamshidi, Y., Kemp, J. P., Lachance, G., Lawson, D., Lek, M., Lopes, M., MacArthur, D. G., Marchini, J., Massimo, M., Mathieson, I., McCarthy, S., Memari, Y., Metrustry, S., Min, J. L., Moayyeri, A., Muddyman, D., Northstone, K., Panoutsopoulou, K., Paternoster, L., Perry, J. R. B., Quaye, L., Richards, J. B., Ring, S., Ritchie, G. R. S., Schiffels, S., Shihab, H. A., Shin, S., Small, K. S., Artigas, M. S., Soranzo, N., Southam, L., Spector, T. D., St Pourcain, B., Surdulescu, G., Tachmazidou, I., Timpson, N. J., Tobin, M. D., Valdes, A. M., Visscher, P. M., Wain, L. V., Walter, K., Ward, K., Wilson, S. G., Wong, K., Yang, J., Zeggini, E., Zhang, F., Zheng, H., Anney, R., Ayub, M., Barrett, J. C., Blackwood, D., Bolton, P. F., Breen, G., Collier, D. A., Craddock, N., Crooks, L., Curran, S., Curtis, D., Durbin, R., Gallagher, L., Geschwind, D., Gurling, H., Holmans, P., Lee, I., Lonnqvist, J., McCarthy, S., McGuffin, P., McIntosh, A. M., McKechanie, A. G., McQuillin, A., Morris, J., Muddyman, D., O'Donovan, M. C., Owen, M. J., Palotie, A., Parr, J. R., Paunio, T., Pietilainen, O., Rehnstrom, K., Sharp, S. I., Skuse, D., St Clair, D., Suvisaari, J., Walters, J. T. R., Williams, H. J., Bochukova, E., Bounds, R., Dominiczak, A., Durbin, R., Keogh, J., Marenne, G., McCarthy, S., Morris, A., Muddyman, D., Porteous, D. J., Smith, B. H., Tachmazidou, I., Wheeler, E., Zeggini, E., Al Turki, S., Anderson, C. A., Antony, D., Beales, P., Bentham, J., Bhattacharya, S., Calissano, M., Carss, K., Chatterjee, K., Cirak, S., Cosgrove, C., Durbin, R., Fitzpatrick, D. R., Floyd, J., Foley, A. R., Franklin, C. S., Futema, M., Grozeva, D., Humphries, S. E., Hurles, M. E., McCarthy, S., Mitchison, H. M., Muddyman, D., Muntoni, F., Onoufriadis, A., Parker, V., Payne, F., Plagnol, V., Raymond, F. L., Roberts, N., Savage, D. B., Scambler, P., Schmidts, M., Schoenmakers, N., Semple, R. K., Serra, E., Spasic-Boskovic, O., Stevens, E., van Kogelenberg, M., Vijayarangakannan, P., Walter, K., Williamson, K. A., Wilson, C., Whyte, T., Ciampi, A., Greenwood, C. M. T., Li, R., Metrustry, S., Oualkacha, K., Tachmazidou, I., Xu, C., Zeggini, E., Bobrow, M., Bolton, P. F., Durbin, R., Fitzpatrick, D. R., Griffin, H., Hurles, M. E., Kaye, J., Kennedy, K., Kent, A., Muddyman, D., Muntoni, F., Raymond, F. L., Semple, R. K., Smee, C., Spector, T. D., Timpson, N. J., Charlton, R., Ekong, R., Futema, M., Humphries, S. E., Khawaja, F., Lopes, L. R., Migone, N., Payne, S. J., Plagnol, V., Pollitt, R. C., Povey, S., Ridout, C. K., Robinson, R. L., Scott, R. H., Shaw, A., Syrris, P., Taylor, R., Vandersteen, A. M., Barrett, J. C., Smith, G. D., Durbin, R., Fitzpatrick, D. R., Hurles, M. E., Kaye, J., Kennedy, K., Langford, C., McCarthy, S., Muddyman, D., Owen, M. J., Palotie, A., Richards, J. B., Soranzo, N., Spector, T. D., Stalker, J., Timpson, N. J., Zeggini, E., Amuzu, A., Casas, J. P., Chambers, J. C., Cocca, M., Dedoussis, G., Gambaro, G., Gasparini, P., Gaunt, T. R., Huang, J., Iotchkova, V., Isaacs, A., Johnson, J., Kleber, M. E., Kooner, J. S., Langenberg, C., Luan, J., Malerba, G., Marz, W., Matchan, A., Min, J. L., Morris, R., Nordestgaard, Børge, Benn, Marianne, Ring, S., Scott, R. A., Soranzo, N., Southam, L., Timpson, N. J., Toniolo, D., Traglia, M., Tybjærg-Hansen, Anne, van Duijn, C. M., van Leeuwen, E. M., Varbo, A., Whincup, P., Zaza, G., Zeggini, E. & Zhang, W., 2019, In: Nature Communications. 10, 14 p., 1718.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

    Fruchart, J., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Després, J., Duriez, P., Eckel, R. H., Ezhov, M. V., Farnier, M., Ginsberg, H. N., Hermans, M. P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W., Krempf, M., Lim, S., Lorenzatti, A. J., McPherson, R., Nuñez-Cortes, J. M., Nordestgaard, Børge, Ogawa, H., Packard, C. J., Plutzky, J., Ponte-Negretti, C. I., Pradhan, A., Ray, K. K., Reiner, Ž., Ridker, P. M., Ruscica, M., Sadikot, S., Shimano, H., Sritara, P., Stock, J. K., Su, T., Susekov, A. V., Tartar, A., Taskinen, M., Tenenbaum, A., Tokgözoğlu, L. S., Tomlinson, B., Tybjærg-Hansen, Anne, Valensi, P., Vrablík, M., Wahli, W., Watts, G. F., Yamashita, S., Yokote, K., Zambon, A. & Libby, P., 2019, In: Cardiovascular Diabetology. 18, 20 p., 71.

    Research output: Contribution to journalReviewResearchpeer-review

  45. 2018
  46. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P., Flannick, J., Grarup, Niels, Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, S., Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    ABCA7 and risk of dementia and vascular disease in the Danish population

    Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals

    Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Advances in lipid-lowering therapy through gene-silencing technologies

    Nordestgaard, Børge, Nicholls, S. J., Langsted, A., Ray, K. K. & Tybjærg-Hansen, Anne, 2018, In: Nature Reviews Cardiology. 15, p. 261-272

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

    European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

    Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W. J., Small, A., Kwee, L. C., Dwivedi, O. P., Prasad, R. B., Bruse, S., Lopez, A. E., Penn, J., Marcketta, A., Leader, J. B., Still, C. D., Kirchner, H. L., Mirshahi, U. L., Wardeh, A. H., Hartle, C. M., Habegger, L., Fetterolf, S. N., Tusie-Luna, T., Morris, A. P., Holm, H., Steinthorsdottir, V., Sulem, P., Thorsteinsdottir, U., Rotter, J. I., Chuang, L. M., Damrauer, S., Birtwell, D., Brummett, C. M., Khera, A. V., Natarajan, P., Orho-Melander, M., Flannick, J., Lotta, L. A., Willer, C. J., Holmen, O. L., Ritchie, M. D., Ledbetter, D. H., Murphy, A. J., Borecki, I. B., Reid, J. G., Overton, J. D., Hansson, O., Groop, L., Shah, S. H., Kraus, W. E., Rader, D. J., Chen, Y. D. I., Hveem, K., Wareham, N. J., Kathiresan, S., Melander, O., Stefansson, K., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Abecasis, G. R., Altshuler, D., Florez, J. C., Boehnke, M., McCarthy, M. I., Yancopoulos, G. D., Carey, D. J., Shuldiner, A. R., Baras, A., Dewey, F. E. & Gromada, J., 2018, In: Nature Communications. 9, 1, 2252.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease

    Qayyum, F., Lauridsen, B. K., Frikke-Schmidt, Ruth, Kofoed, Klaus Fuglsang, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 22, p. 2106-2116 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 924951