Anne Tybjærg-Hansen
Clinical Professor
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Response to the Letter: Response to "Use of biomarkers to identify new drug targets and to predict risk of cardiometabolic outcomes" by Abasi A., et al
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Feb 2016, In: The Journal of clinical endocrinology and metabolism. 101, 2, p. L22-L23Research output: Contribution to journal › Letter › Research › peer-review
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A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease
Holmes, M. V., Frikke-Schmidt, R., Melis, D., Luben, R., Asselbergs, F. W., Boer, J. M. A., Cooper, J., Palmen, J., Horvat, P., Engmann, J., Li, K-W., Onland-Moret, N. C., Hofker, M. H., Kumari, M., Keating, B. J., Hubacek, J. A., Adamkova, V., Kubinova, R., Bobak, M., Khaw, K-T. & 6 others, , Nov 2014, In: Atherosclerosis. 237, 1, p. 5-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretory Phospholipase A2-IIA and Cardiovascular Disease
Holmes, M. V., Simon, T., Exeter, H. J., Folkersen, L. W., Asselbergs, F. W., Guardiola, M., Cooper, J. A., Palmen, J., Hubacek, J. A., Carruthers, K. F., Horne, B. D., Brunisholz, K. D., Mega, J. L., van Iperen, E. P. A., Li, M., Leusink, M., Trompet, S., Verschuren, J. J. W., Hovingh, G. K., Dehghan, A. & 93 others, , 2013, In: Journal of the American College of Cardiology. 62 , 21, p. 1966–1976 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygosity for R1141X in Abcc6 and Risk of Ischemic Vascular Disease
Hornstrup, L. S., Tybjaerg-Hansen, A., Haase, C. L., Nordestgaard, Børge, Grande, P., Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 38 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy
Hornstrup, L. S., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jun 2013, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 6, p. 1441-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygosity for R1141X in ABCC6 and risk of ischemic vascular disease
Hornstrup, L. S., Tybjærg-Hansen, Anne, Haase, C. L., Nordestgaard, Børge, Sillesen, H., Grande, P. & Frikke-Schmidt, R., 2011, In: Circulation: Cardiovascular Genetics. 4, 5, p. 534-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W. K., Young, R., Paul, D. S., Waite, L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H-H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A. & 36 others, , 2017, In: Nature Genetics. 49, p. 1113-1119Research output: Contribution to journal › Letter › Research › peer-review
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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
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Systematically missing confounders in individual participant data meta-analysis of observational cohort studies
Jackson, D., White, I., Kostis, J. B., Wilson, A. C., Folsom, A. R., Wu, K., Chambless, L., Benderly, M., Goldbourt, U., Willeit, J., Kiechl, S., Yarnell, J. W., Sweetnam, P. M., Elwood, P. C., Cushman, M., Psaty, B. M., Tracy, R. P., Tybjaerg-Hansen, A., Haverkate, F., Maat, M. P. D. & 98 others, , 2009, In: Statistics in Medicine. 28, 8, p. 1218-1237 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease
Johannsen, T. H., Kamstrup, P. R., Andersen, R. V., Jensen, G. B., Sillesen, Henrik, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1264-73 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects
Johannsen, T. H., Frikke-Schmidt, R., Schou, J., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: Journal of the American College of Cardiology. 60, 20, p. 2041-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma YKL-40 and total and disease-specific mortality in the general population
Johansen, Julia Sidenius, Bojesen, Stig Egil, Tybjærg-Hansen, Anne, Mylin, A. K., Price, P. A. & Nordestgaard, Børge, 1 Oct 2010, In: Clinical Chemistry. 56, 10, p. 1580-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Common Genetic Variation in Apoa5, Levels of Triglycerides and Risk of Myocardial Infarction in the General Population
Jorgensen, A. B., Frikke-Schmidt, Ruth, Grande, P., Nordestgaard, Børge, Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 89 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies
Joshi, A. D., Andersson, C., Buch, S., Stender, S., Noordam, R., Weng, L-C., Weeke, P. E., Auer, P. L., Boehm, B., Chen, C., Choi, H., Curhan, G., Denny, J. C., De Vivo, I., Eicher, J. D., Ellinghaus, D., Folsom, A. R., Fuchs, C., Gala, M., Haessler, J. & 35 others, , Aug 2016, In: Gastroenterology. 151, 2, 351 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factor V leiden homozygosity, dyspnea, and reduced pulmonary function.
Juul, K., Tybjærg-Hansen, A., Lange, P., Vestbo, J., Nordestgaard, B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2005, In: Archives of Internal Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease
Juul, K., Tybjærg-Hansen, A., Marklund, S., Lange, Peter, Nordestgaard, B. G. & Tybjærg-Hansen, Anne, 2006, In: American Journal of Respiratory and Critical Care Medicine. 173, 8, p. 858-64Research output: Contribution to journal › Journal article › Research › peer-review
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Genetisk betinget reduktion i antioxidativ beskyttelse og øget risiko for iskaemisk hjertesygdom--sekundaerpublikation
Juul, K., Tybjærg-Hansen, Anne, Marklund, S., Heegaard, N. H. H., Steffensen, R., Sillesen, H. H., Jensen, G. B. & Nordestgaard, Børge, 2005, In: Ugeskrift for Laeger. 167, 7, p. 767-70 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood–brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals
Juul Rasmussen, I., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2019, In: European Journal of Epidemiology. 34, 6, p. 579-590 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention
Juul Rasmussen, I., Rasmussen, K. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: European Heart Journal. 41, 41, p. 4024-4033 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physical activity in leisure time and at work and risk of dementia: A prospective cohort study of 117,616 individuals
Juul Rasmussen, I., Rasmussen, Katrine Laura, Thomassen, J. Q., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Atherosclerosis. 360, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
Jørgensen, A. B., Frikke-Schmidt, R., West, A. S., Grande, P., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: European Heart Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
Jørgensen, A. B., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jul 2014, In: New England Journal of Medicine. 371, 1, p. 32-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pentanucleotide repeat polymorphism, lipoprotein(a) levels, and risk of ischemic heart disease
Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R. & Nordestgaard, B. G., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3769-3776 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 11 Feb 2014, In: Journal of the American College of Cardiology. 63, 5, p. 470-477 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated lipoprotein(a) and increased risk of myocardial infarction
Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R., Nordestgaard, B. G., Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R. & Nordestgaard, Børge, 2009, In: JAMA - Journal of the American Medical Association. 301, 22, p. 2331-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) and risk of myocardial infarction--genetic epidemiologic evidence of causality
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 87-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme lipoprotein(a) levels and risk of myocardial infarction in the general population: the Copenhagen City Heart Study
Kamstrup, P. R., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2008, In: Circulation. 117, 2, p. 176-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme lipoprotein(a) levels and improved cardiovascular risk prediction
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 19 Mar 2013, In: Journal of the American College of Cardiology. 61, 11, p. 1146-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 7, p. 1732-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein, fibrinogen, and cardiovascular disease prediction
Kaptoge, S., Di Angelantonio, E., Pennells, L., Wood, A. M., White, I. R., Gao, P., Walker, M., Thompson, A., Sarwar, N., Caslake, M., Butterworth, A. S., Amouyel, P., Assmann, G., Bakker, S. J. L., Barr, E. L. M., Barrett-Connor, E., Benjamin, E. J., Björkelund, C., Brenner, H., Brunner, E. & 31 others, , 2012, In: New England Journal of Medicine. 367, 14, p. 1310-20 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism
Karuna, R., Holleboom, A. G., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Georgopoulos, S., van Eck, M., van Berkel, T. J. C., von Eckardstein, A. & Rentsch, K. M., 1 Feb 2011, In: Atherosclerosis. 214, 2, p. 448-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CYP1B1 genotype and risk of cardiovascular disease, pulmonary disease, and cancer in 50,000 individuals
Knudsen, Diljit Kaur, Nordestgaard, B. G., Tybjærg-Hansen, Anne & Bojesen, S. E., 2009, In: Pharmacogenetics and Genomics (Print Edition). 19, 9, p. 685-694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study
Kaur-Knudsen, D., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Journal of Clinical Oncology. 29, 21, p. 2875-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals
Khan, T. A., Shah, T., Prieto, D., Zhang, W., Price, J., Fowkes, G. R., Cooper, J., Talmud, P. J., Humphries, S. E., Sundstrom, J., Hubacek, J. A., Ebrahim, S., Lawlor, D. A., Ben-Shlomo, Y., Abdollahi, M. R., Slooter, A. J. C., Szolnoki, Z., Sandhu, M., Wareham, N., Frikke-Schmidt, R. & 29 others, , 2013, In: International Journal of Epidemiology. 42, 2, p. 475-492 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Estrogen receptor alpha polymorphism and risk of cardiovascular disease, cancer, and hip fracture: cross-sectional, cohort, and case-control studies and a meta-analysis
Kjaergaard, A., Ellervik, C., Tybjaerg-Hansen, A., Axelsson, C., Grønholdt, M., Grande, P., Jensen, G. B., Nordestgaard, B., Tybjærg-Hansen, Anne, Kjaergaard, A. D., Ellervik, Christina, Axelsson, C. K., Grønholdt, M., Grande, P. & Nordestgaard, Børge, 2007, In: Circulation. 115, 7, p. 861-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adherence to dietary guidelines and risk of dementia: a prospective cohort study of 94 184 individuals
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Epidemiology and Psychiatric Sciences. 31, e71.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of diet on ten-year absolute cardiovascular risk in a prospective cohort of 94 321 individuals: A tool for implementation of healthy diets
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: The Lancet Regional Health - Europe. 19, 100419.Research output: Contribution to journal › Journal article › Research › peer-review
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ABCA7 and risk of dementia and vascular disease in the Danish population
Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma high-density lipoprotein cholesterol and risk of dementia: observational and genetic studies
Kjeldsen, E. W., Thomassen, J. Q., Juul Rasmussen, I., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Cardiovascular Research. 118, 5, p. 1330-1343 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated Fibrinogen Levels Associate with Risk of Pulmonary Embolism, but not with Deep Venous Thrombosis
Klovaite, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, M., 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 3, p. 286-93Research output: Contribution to journal › Journal article › Research › peer-review
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Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer
Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 538-540Research output: Contribution to journal › Review › Research › peer-review
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Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 515-537Research output: Contribution to journal › Review › Research › peer-review
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Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 498-514Research output: Contribution to journal › Journal article › Research › peer-review
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Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
Kote-Jarai, Z., Olama, A. A. A., Giles, G. G., Severi, G., Schleutker, J., Weischer, M., Campa, D., Riboli, E., Key, T., Gronberg, H., Hunter, D. J., Kraft, P., Thun, M. J., Ingles, S., Chanock, S., Albanes, D., Hayes, R. B., Neal, D. E., Hamdy, F. C., Donovan, J. L. & 31 others, , 2011, In: Nature Genetics. 43, 8, p. 785-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Kozlitina, J., Smagris, E., Stender, Stefan, Nordestgaard, Børge, Zhou, H. H., Tybjærg-Hansen, Anne, Vogt, T. F., Hobbs, H. H. & Cohen, J. C., Apr 2014, In: Nature Genetics. 46, 4, p. 352-356 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of APOE ε Genotype on Lipoprotein(a) and the Associated Risk of Myocardial Infarction and Aortic Valve Stenosis
Kritharides, L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Kamstrup, P. R. & Afzal, Shoaib, 1 Sep 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 9, p. 3390-3399 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High fat in blood and body and increased risk of clinically diagnosed non-alcoholic fatty liver disease in 105,981 individuals
Kyhl, L. K., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Nielsen, S. F., 2023, In: Atherosclerosis. 376, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: the Copenhagen City Heart Study with 31 years of follow-up
Langsted, A., Freiberg, J. J., Tybjaerg-Hansen, A., Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2011, In: Journal of Internal Medicine. 270, 1, p. 65-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 730-731 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
Research output: Contribution to journal › Journal article › Research › peer-review
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252
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The UK10K project identifies rare variants in health and disease
Research output: Contribution to journal › Journal article › Research › peer-review
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
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