Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor

Member of:

  • Clinical Biochemistry


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  1. Published

    Repositioning of the global epicentre of non-optimal cholesterol

    NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Taddei, C., Zhou, B., Bixby, H., Nordestgaard, Børge, Benn, Marianne, Linneberg, Allan René, Tybjærg-Hansen, Anne, Cisneros, J. Z., Gregg, E. W., Ezzati, M. & Sørensen, Thorkild I.A., 2020, In: Nature. 582, 7810, p. 73-77

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

    EADB contributors, E. C., The GR@ACE study group, T. G. S. G., DEGESCO consortium, D. C., IGAP (ADGC, CHARGE, EADI, GERAD), I. (. C. E. G. & PGC-ALZ consortia, P. C., Dec 2021, In: Nature Communications. 12, 1, 16 p., 3417.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

    Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, Lu, Y., Zhang, W., Imran, A., Abbas, S., Majeed, F., Trindade, K., Qamar, N., Mallick, N. H., Yaqoob, Z., Saghir, T., Rizvi, S. N. H., Memon, A., Rasheed, S. Z., Memon, F., Mehmood, K., Ahmed, N., Qureshi, I. H., Tanveer-Us-Salam, Iqbal, W., Malik, U., Mehra, N., Kuo, J. Z., Sheu, W. H., Guo, X., Hsiung, C. A., Juang, J. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Benn, Marianne, Frikke-Schmidt, Ruth & CHD Exome+ Consortium, C. E. C., Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

    CHD Exome+ Consortium, C. E. C., CARDIoGRAM Exome Consortium, C. E. C. & Global Lipids Genetics Consortium, G. L. G. C., 11 Mar 2016, In: Science (New York, N.Y.). 351, 6278, p. 1166-71 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome

    Zanoni, P., Panteloglou, G., Othman, A., Haas, J. T., Meier, R., Rimbert, A., Futema, M., Khalil, Y. A., Norrelykke, S. F., Rzepiela, A. J., Stoma, S., Stebler, M., Van Dijk, F., Wijers, M., Wolters, J. C., Dalila, N., Huijkman, N. C. A., Smit, M., Gallo, A., Carreau, V. & 26 others, Philippi, A., Rabès, J. P., Boileau, C., Visentin, M., Vonghia, L., Weyler, J., Francque, S., Verrijken, A., Verhaegen, A., Van Gaal, L., Van Der Graaf, A., Van Rosmalen, B. V., Robert, J., Velagapudi, S., Yalcinkaya, M., Keel, M., Radosavljevic, S., Geier, A., Tybjærg-Hansen, Anne, Varret, M., Rohrer, L., Humphries, S. E., Staels, B., Van De Sluis, B., Kuivenhoven, J. A. & Von Eckardstein, A., 2022, In: Circulation Research. 130, 1, p. 80-95 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    C-reactive protein and all-cause mortality--the Copenhagen City Heart Study

    Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Jul 2010, In: European Heart Journal. 31, 13, p. 1624-32 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls

    Zacho, J., Yazdanyar, S., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: International Journal of Cancer. 128, 3, p. 644-52 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    C-reaktivt protein og risiko for iskæmisk hjerte- og cerebrovaskulær sygdom - sekundærpublikation

    Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, Børge, 2009, In: Ugeskrift for læger. 171, p. 1751-1755

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease

    Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2009, In: Scandinavian Journal of Clinical & Laboratory Investigation. 69, 4, p. 442-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts

    Zacho, J., Benfield, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    C-reactive protein and risk of venous thromboembolism in the general population

    Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Aug 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 8, p. 1672-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    C-reaktivt protein og risiko for iskaemisk hjerte- og cerebrovaskulaer sygdom--sekundaerpublikation

    Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 21, p. 1751-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Genetically elevated C-reactive protein and ischemic vascular disease

    Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2008, In: New England Journal of Medicine. 359, 18, p. 1897-1908 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    [C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication]

    Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 21, p. 1751-1755 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Penetrance of NOD2/CARD15 genetic variants in the general population

    Yazdanyar, S., Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 20 Apr 2010, In: C M A J. 182, 7, p. 661-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

    Yang, Y., van der Klaauw, A. A., Zhu, L., Cacciottolo, T. M., He, Y., Stadler, L. K. J., Wang, C., Xu, P., Saito, K., Hinton, A., Yan, X., Keogh, J. M., Henning, E., Banton, M. C., Hendricks, A. E., Bochukova, E. G., Mistry, V., Lawler, K. L., Liao, L., Xu, J. & 306 others, O'Rahilly, S., Tong, Q., Barroso, I., O'Malley, B. W., Farooqi, I. S., Xu, Y., Balasubramanian, S., Clapham, P., Coates, G., Cox, T., Daly, A., Danecek, P., Du, Y., Durbin, R., Edkins, S., Ellis, P., Flicek, P., Guo, X., Guo, X., Huang, L., Jackson, D. K., Joyce, C., Keane, T., Kolb-Kokocinski, A., Langford, C., Li, Y., Liang, J., Lin, H., Liu, R., Maslen, J., McCarthy, S., Muddyman, D., Quail, M. A., Stalker, J., Sun, J., Tian, J., Wang, G., Wang, J., Wang, Y., Wong, K., Zhang, P., Birney, E., Boustred, C., Brion, M., Chen, L., Clement, G., Danecek, P., Smith, G. D., Day, I. N. M., Day-Williams, A., Down, T., Dunham, I., Durbin, R., Evans, D. M., Fatemifar, G., Gaunt, T. R., Geihs, M., Greenwood, C. M. T., Hart, D., Howie, B., Huang, J., Hubbard, T., Hysi, P., Iotchkova, V., Jamshidi, Y., Kemp, J. P., Lachance, G., Lawson, D., Lek, M., Lopes, M., MacArthur, D. G., Marchini, J., Massimo, M., Mathieson, I., McCarthy, S., Memari, Y., Metrustry, S., Min, J. L., Moayyeri, A., Muddyman, D., Northstone, K., Panoutsopoulou, K., Paternoster, L., Perry, J. R. B., Quaye, L., Richards, J. B., Ring, S., Ritchie, G. R. S., Schiffels, S., Shihab, H. A., Shin, S., Small, K. S., Artigas, M. S., Soranzo, N., Southam, L., Spector, T. D., St Pourcain, B., Surdulescu, G., Tachmazidou, I., Timpson, N. J., Tobin, M. D., Valdes, A. M., Visscher, P. M., Wain, L. V., Walter, K., Ward, K., Wilson, S. G., Wong, K., Yang, J., Zeggini, E., Zhang, F., Zheng, H., Anney, R., Ayub, M., Barrett, J. C., Blackwood, D., Bolton, P. F., Breen, G., Collier, D. A., Craddock, N., Crooks, L., Curran, S., Curtis, D., Durbin, R., Gallagher, L., Geschwind, D., Gurling, H., Holmans, P., Lee, I., Lonnqvist, J., McCarthy, S., McGuffin, P., McIntosh, A. M., McKechanie, A. G., McQuillin, A., Morris, J., Muddyman, D., O'Donovan, M. C., Owen, M. J., Palotie, A., Parr, J. R., Paunio, T., Pietilainen, O., Rehnstrom, K., Sharp, S. I., Skuse, D., St Clair, D., Suvisaari, J., Walters, J. T. R., Williams, H. J., Bochukova, E., Bounds, R., Dominiczak, A., Durbin, R., Keogh, J., Marenne, G., McCarthy, S., Morris, A., Muddyman, D., Porteous, D. J., Smith, B. H., Tachmazidou, I., Wheeler, E., Zeggini, E., Al Turki, S., Anderson, C. A., Antony, D., Beales, P., Bentham, J., Bhattacharya, S., Calissano, M., Carss, K., Chatterjee, K., Cirak, S., Cosgrove, C., Durbin, R., Fitzpatrick, D. R., Floyd, J., Foley, A. R., Franklin, C. S., Futema, M., Grozeva, D., Humphries, S. E., Hurles, M. E., McCarthy, S., Mitchison, H. M., Muddyman, D., Muntoni, F., Onoufriadis, A., Parker, V., Payne, F., Plagnol, V., Raymond, F. L., Roberts, N., Savage, D. B., Scambler, P., Schmidts, M., Schoenmakers, N., Semple, R. K., Serra, E., Spasic-Boskovic, O., Stevens, E., van Kogelenberg, M., Vijayarangakannan, P., Walter, K., Williamson, K. A., Wilson, C., Whyte, T., Ciampi, A., Greenwood, C. M. T., Li, R., Metrustry, S., Oualkacha, K., Tachmazidou, I., Xu, C., Zeggini, E., Bobrow, M., Bolton, P. F., Durbin, R., Fitzpatrick, D. R., Griffin, H., Hurles, M. E., Kaye, J., Kennedy, K., Kent, A., Muddyman, D., Muntoni, F., Raymond, F. L., Semple, R. K., Smee, C., Spector, T. D., Timpson, N. J., Charlton, R., Ekong, R., Futema, M., Humphries, S. E., Khawaja, F., Lopes, L. R., Migone, N., Payne, S. J., Plagnol, V., Pollitt, R. C., Povey, S., Ridout, C. K., Robinson, R. L., Scott, R. H., Shaw, A., Syrris, P., Taylor, R., Vandersteen, A. M., Barrett, J. C., Smith, G. D., Durbin, R., Fitzpatrick, D. R., Hurles, M. E., Kaye, J., Kennedy, K., Langford, C., McCarthy, S., Muddyman, D., Owen, M. J., Palotie, A., Richards, J. B., Soranzo, N., Spector, T. D., Stalker, J., Timpson, N. J., Zeggini, E., Amuzu, A., Casas, J. P., Chambers, J. C., Cocca, M., Dedoussis, G., Gambaro, G., Gasparini, P., Gaunt, T. R., Huang, J., Iotchkova, V., Isaacs, A., Johnson, J., Kleber, M. E., Kooner, J. S., Langenberg, C., Luan, J., Malerba, G., Marz, W., Matchan, A., Min, J. L., Morris, R., Nordestgaard, Børge, Benn, Marianne, Ring, S., Scott, R. A., Soranzo, N., Southam, L., Timpson, N. J., Toniolo, D., Traglia, M., Tybjærg-Hansen, Anne, van Duijn, C. M., van Leeuwen, E. M., Varbo, A., Whincup, P., Zaza, G., Zeggini, E. & Zhang, W., 2019, In: Nature Communications. 10, 14 p., 1718.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)

    Yang, X., Sethi, A. A., Yanek, L. R., Knapper, C., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Becker, D. M., Mathias, R. A., Remaley, A. T. & Becker, L. C., Oct 2016, In: Circulation: Cardiovascular Genetics. 9, 5, p. 408-418 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease: A Note on Mendelian Randomization Studies

    Würtz, P., Kangas, A. J., Soininen, P., Lehtimäki, T., Kähönen, M., Viikari, J. S., Raitakari, O. T., Järvelin, M., Davey Smith, G., Ala-Korpela, M., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2013, In: Journal of the American College of Cardiology. 62, 20, p. 1906-8 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals

    Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies

    Wormser, D., Kaptoge, S., Di Angelantonio, E., Wood, A. M., Pennells, L., Thompson, A., Sarwar, N., Kizer, J. R., Lawlor, D. A., Nordestgaard, B. G., Ridker, P., Salomaa, V., Stevens, J., Woodward, M., Sattar, N., Collins, R., Thompson, S. G., Whitlock, G., Danesh, J., Emerging Risk Factors Collaboration & 2 others, Tybjærg-Hansen, Anne & Frikke-Schmidt, R., 2011, In: Lancet. 377, 9771, p. 1085-95 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Combined analysis of six lipoprotein lipase genetic variants on triglycerides, high-density lipoprotein, and ischemic heart disease: cross-sectional, prospective, and case-control studies from the Copenhagen City Heart Study

    Wittrup, H. H., Andersen, R. V., Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 4, p. 1438-45 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Combined analysis of six lipoprotein lipase genetic variants on triglycerides, high-density lipoprotein, and ischemic heart disease: cross-sectional, prospective, and case-control studies from the Copenhagen City Heart Study.

    Wittrup, H., Andersen, R., Tybjærg-Hansen, A., Jensen, G. B., Nordestgaard, B. & Tybjærg-Hansen, Anne, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 4, p. 1438-45

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

    Wiegman, A., Gidding, S. S., Watts, G. F., Chapman, M. J., Ginsberg, H. N., Cuchel, M., Ose, L., Averna, M., Boileau, C., Borén, J., Bruckert, E., Catapano, A. L., Defesche, J. C., Descamps, O. S., Hegele, R. A., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Kuivenhoven, J. A., Masana, L. & 13 others, Nordestgaard, Børge, Pajukanta, P., Parhofer, K. G., Raal, F. J., Ray, K. K., Santos, R. D., Stalenhoef, A. F. H., Steinhagen-Thiessen, E., Stroes, E. S., Taskinen, M., Tybjærg-Hansen, Anne, Wiklund, O. & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2425-37 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

    Wensley, F., Gao, P., Burgess, S., Kaptoge, S., Di Angelantonio, E., Shah, T., Engert, J. C., Clarke, R., Davey-Smith, G., Nordestgaard, B. G., Saleheen, D., Samani, N. J., Sandhu, M., Anand, S., Pepys, M. B., Smeeth, L., Whittaker, J., Casas, J. P., Thompson, S. G., Hingorani, A. D. & 3 others, Danesh, J., C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC), C. R. P. C. H. D. G. C. (. & Tybjærg-Hansen, Anne, 2011, In: B M J. 342, p. d548

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls

    Weischer, M., Bojesen, Stig Egil, Ellervik, C., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Oncology. 26, 4, p. 542-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 924951