Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor

Member of:

  • Clinical Biochemistry


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  1. Published

    Major lipids, apolipoproteins and risk of vascular disease.

    (Tybjaerg-Hansen, A. ). T. E. R. F. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: JAMA - Journal of the American Medical Association. 302, p. 1993-2000 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality

    (Tybjaerg-Hansen, A. ). T. F. S. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: JAMA - Journal of the American Medical Association. 302, 4, p. 412-423 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Measures to assess the prognostic ability of the stratified Cox proportional hazards model

    (Tybjaerg-Hansen, A. ). T. F. S. C. T. C. C. H. S. & Tybjærg-Hansen, Anne, 2009, In: Statistics in Medicine. 28, 3, p. 389-411 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    BODY MASS INDEX AND MORTALITY OVER 3 DECADES

    Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, Sep 2016, In: Atherosclerosis. 252, p. E222-E222 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  5. Published

    Change in Body Mass Index Associated With Lowest Mortality in Denmark, 1976-2013

    Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, 10 May 2016, In: JAMA - Journal of the American Medical Association. 315, 18, p. 1989-1996 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    C-reactive protein and the risk of cancer: a mendelian randomization study

    Allin, K. H., Nordestgaard, Børge, Zacho, J., Tybjærg-Hansen, Anne & Bojesen, Stig Egil, 2010, In: National Cancer Institute. Journal (Print). 102, 3, p. 202-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease

    Argraves, K. M., Sethi, A. A., Gazzolo, P. J., Wilkerson, B. A., Remaley, A. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Yeatts, S. D., Nicholas, K. S., Barth, J. L. & Argraves, W. S., 2011, In: Lipids in Health and Disease. 10, p. 70

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Surfactant Protein-B 121ins2 Heterozygosity, Reduced Pulmonary Function, and Chronic Obstructive Pulmonary Disease in Smokers

    Baekvad-Hansen, M., Dahl, Morten, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 1 Jan 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Two novel mutations in surfactant protein-C, lung function and obstructive lung disease

    Baekvad-Hansen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Dahl, M., 2010, In: Respiratory Medicine. 104, 3, p. 418-425

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Dynamic and Multifaceted Nature of Cardiovascular Disease and Using Genetic Testing to Inform Clinical Care: An International Perspective

    Baudhuin, L. M., De Backer, J., Ingles, J., Milewicz, D. M. & Tybjærg-Hansen, Anne, 2021, In: Clinical Chemistry. 67, 1, p. 33-40 8 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  11. Published

    Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study

    Benfield, T., Ejrnæs, K., Juul, K., Ostergaard, C., Helweg-Larsen, J., Weis, N., Munthe-Fog, L., Kronborg, G., Andersen, M. R., Tybjærg-Hansen, A., Nordestgaard, B. G., Garred, P., Benfield, T., Ejrnaes, K., Juul, K., Andersen, C. Ø., Helweg-Larsen, J., Weis, N. M., Munthe-Fog, L., Kronborg, G. & 4 others, Andersen, M. R., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Garred, Peter, 1 Jan 2010, In: Critical Care (Online Edition). 14, 2, p. R28

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Influence of the factor V Leiden mutation on infectious disease susceptibility and outcome: a population-based study

    Benfield, Thomas, Dahl, M., Nordestgaard, B. G., Tybjærg-Hansen, Anne & Dahl, M., 15 Nov 2005, In: Journal of Infectious Diseases. 192, 10, p. 1851-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Common and Rare Alleles in Apolipoprotein B Contribute to Plasma Levels of LDL Cholesterol in the General Population.

    Benn, M., Stene, M., Nordestgaard, B., Jensen, G. B., Steffensen, R., Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1038-45

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Improving prediction of ischemic cardiovascular disease in the general population using apolipoprotein B: the Copenhagen City Heart Study

    Benn, M., Nordestgaard, B., Jensen, G. B., Tybjaerg-Hansen, A., Tybjærg-Hansen, Anne, Benn, M. & Nordestgaard, Børge, 2007, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 3, p. 661-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Common and rare alleles in apolipoprotein B contribute to plasma levels of low-density lipoprotein cholesterol in the general population

    Benn, Marianne, Stene, M. C. A., Nordestgaard, Børge, Jensen, G. B., Steffensen, R. & Tybjærg-Hansen, Anne, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1038-1045 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Impact of glucose on risk of dementia: Mendelian randomisation studies in 115,875 individuals

    Benn, Marianne, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: Diabetologia. 63, p. 1151-1161

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study

    Benn, Marianne, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 24 Apr 2017, In: B M J. 357, 11 p., j1648.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Nonfasting glucose, ischemic heart disease, and myocardial infarction: a Mendelian randomization study

    Benn, M., Tybjærg-Hansen, Anne, McCarthy, M. I., Jensen, G. B., Grande, P. & Nordestgaard, Børge, 2012, In: Journal of the American College of Cardiology. 59, 25, p. 2356-65 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mitochondrial haplogroups: ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population

    Benn, M., Schwartz, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2008, In: Circulation. 117, 19, p. 2492-501 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Polymorphism in APOB associated with increased low-density lipoprotein levels in both genders in the general population

    Benn, M., Nordestgaard, Børge, Jensen, J. S., Grande, P., Sillesen, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 10, p. 5797-803 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis

    Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    High body mass index and cancer risk

    Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study

    Benn, Marianne, Tybjærg-Hansen, Anne, Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Benn, M., 16 Mar 2011, In: National Cancer Institute. Journal (Print). 103, 6, p. 508-19 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 3956-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals

    Benn, Marianne, Marott, S. C. W., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: Cardiovascular Research. 118, 18, p. 3576-3585 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor

    Benn, M., Nordestgaard, Børge, Jensen, J. S., Nilausen, K. S., Meinertz, H. & Tybjærg-Hansen, Anne, 2005, In: Journal of Biological Chemistry. 280, 22, p. 21052-60 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality

    Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3102-3114

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Polymorphisms in apolipoprotein B and risk of ischemic stroke

    Benn, M., Nordestgaard, Børge, Jensen, J. S. & Tybjærg-Hansen, Anne, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 9, p. 3611-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women

    Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses

    Benn, Marianne, Nordestgaard, Børge, Grande, P., Schnohr, P., Tybjærg-Hansen, Anne & Benn, M., 22 Jun 2010, In: Journal of the American College of Cardiology. 55, 25, p. 2833-42 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    European Lipoprotein Club: report of the 31st ELC Annual Conference, Tutzing, 8-11 September 2008

    Bernini, F., Freeman, D., Groen, A., Heeren, J., Kalopissis, A., Kronenberg, F., Lindstedt, K., Parini, P., Schuster, G., Tybjærg-Hansen, Anne, Dij, K. W. V. & Eckardstein, A. V., 2009, In: Atherosclerosis. 205, 1, p. 41-47 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010

    Bernini, F., Fisher, R., Freeman, D., Groen, A., Kalopissis, A., Malle, E., Mulder, M., Niemeier, A., Parini, P., Tybjærg-Hansen, Anne & von Eckardstein, A., 2011, In: Atherosclerosis. 215, 1, p. 249-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011

    Bernini, F., Costet, P., Ehrenborg, E., Fisher, R., Fielding, B., Freeman, D., Groen, A., Malle, E., Mulder, M., Niemeier, A., Tybjærg-Hansen, Anne & von Eckardstein, A., 2012, In: Atherosclerosis. 221, p. 287-93

    Research output: Contribution to journal › Journal article › Research

  35. Published

    Common genetic variation in mc4r does not affect atherosclerotic plaque phenotypes and cardiovascular disease outcomes

    Blauw, L. L., Noordam, R., van der Laan, S. W., Trompet, S., Kooijman, S., van Heemst, D., Jukema, J. W., van Setten, J., de Borst, G. J., Tybjærg-Hansen, Anne, Pasterkamp, G., Berbée, J. F. P. & Rensen, P. C. N., 2021, In: Journal of Clinical Medicine. 10, 5, 12 p., 932.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm

    Bottolo, L., Chadeau-Hyam, M., Hastie, D. I., Zeller, T., Liquet, B., Newcombe, P., Yengo, L., Wild, P. S., Schillert, A., Ziegler, A., Nielsen, S. F., Butterworth, A. S., Ho, W. K., Castagné, R., Munzel, T., Tregouet, D., Falchi, M., Cambien, F., Nordestgaard, B., Fumeron, F. & 7 others, Tybjærg-Hansen, Anne, Froguel, P., Danesh, J., Petretto, E., Blankenberg, S., Tiret, L. & Richardson, S., 2013, In: P L o S Genetics. 9, 8, p. 1-17 17 p., e1003657.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

    Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., Gretarsdottir, S., Badger, S. A., Bradley, D. T., Burnand, K., Child, A. H., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, S., Johnson, A., Sohrabi, S., Smith, A., Thompson, M. M. & 31 others, van Bockxmeer, F. M., Waltham, M., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A. W., Wijmenga, C., de Graaf, J., Kiemeney, L. A., Assimes, T. L., McPherson, R., Folkersen, L. W., Franco-Cereceda, A., Palmen, J., Smith, F. A., Sylvius, N., Wild, J. B., Refstrup, M., Edkins, S., Gwilliam, R., Hunt, S. E., Potter, S., Lindholt, J. S., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Hughes, A. E., Golledge, J., Norman, P. E., van Rij, A. & CARDIoGRAM Consortium, C. C., 2011, In: American Journal of Human Genetics. 89, 5, p. 619-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Genetic variants in SUSD2 are associated with the risk of ischemic heart disease

    Bruikman, C. S., Dalila, N., van Capelleveen, J. C., Kroon, J., Peter, J., Havik, S. R., Willems, M., Huisman, L. C., de Boer, O. J., Hovingh, G. K., Tybjærg-Hansen, Anne & Dallinga-Thie, G. M., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 470-481

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    25-hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants

    Brøndum-Jacobsen, P., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: Journal of Thrombosis and Haemostasis. 11, 3, p. 423-431

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Genomet i kardiologien

    Bundgård, Henning, Diness, Birgitte Rode, Tfelt-Hansen, Jacob, Henriksen, F. L., Eschen, O., Skovby, F., Havndrup, O., Jensen, H. K. & Tybjærg-Hansen, Anne, 2014, In: Ugeskrift for Laeger. 176, 46, 5 p., V06140376.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis

    European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables

    Burgess, S., Thompson, S. G., Thompson, G., Andrews, G., Samani, N. J., Hall-Andersen, A. M., Whincup, P., Morris, R., Lawlor, D. A., Davey Smith, G., Timpson, N., Ebrahim, S., Ben-Shlomo, Y., Brown, M., Ricketts, S., Sandhu, M., Reiner, A., Psaty, B., Lange, L., Cushman, M. & 31 others, Hung, J., Thompson, P., Beilby, J., Warrington, N., Palmer, L. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Zacho, J., Wu, C., Lowe, G., Tzoulaki, I., Perera, M. K., Yamamoto, J. F., Chiodini, B., Franzosi, M., Hankey, G. J., Jamrozik, K., Palmer, L., Rimm, E., Pai, J., Heckbert, S., Bis, J., Anand, S., Engert, J., Collins, R., Clarke, R., Melander, O., Berglund, G., Ladenvall, P., Johansson, L. & CRP CHD Genetics Collaboration, C. C. G. C., 30 May 2010, In: Statistics in Medicine. 29, 12, p. 1298-311 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Surfactant protein-B 121ins2 heterozygosity, reduced pulmonary function, and chronic obstructive pulmonary disease in smokers

    Bækvad-Hansen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Jan 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Surfactant Protein-B 121ins2 Heterozygosity, Reduced Pulmonary Function and COPD in Smokers

    Bækvad-Hansen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study

    Carter, A. R., Borges, M., Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Nordestgaard, Børge & Lawlor, D. A., 2019, In: JAMA Network Open. 2, 3, 14 p., e190305.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

    Chapman, M. J., Ginsberg, H. N., Amarenco, P., Andreotti, F., Borén, J., Catapano, A. L., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik, P., Masana, L., Nordestgaard, Børge, Ray, K. K., Reiner, Z., Taskinen, M., Tokgözoglu, L., Tybjærg-Hansen, Anne, Watts, G. F. & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 2011, In: European Heart Journal (English Edition). 32, 11, p. 1345-61 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy

    Christensen, Alex Hørby, Andersen, C. B., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Clinical Genetics. 80, 3, p. 256-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Wide spectrum of desmosomal mutations in Danish patients with arrhythmogenic right ventricular cardiomyopathy

    Christensen, A. H., Benn, M., Bundgaard, H., Tybjærg-Hansen, Anne, Haunsø, Stig & Svendsen, Jesper Hastrup, Nov 2010, In: Journal of Medical Genetics. 47, 11, p. 736-44 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients - disease - causing or innocent bystanders?

    Christensen, A. H., Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, J. H., 2009, In: Cardiology. 115, 2, p. 148-154 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?

    Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S., Svendsen, Jesper Hastrup, Christensen, A. H., Benn, M., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 1 Jan 2010, In: Cardiology. 115, 2, p. 148-54 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Screening of Three Novel Candidate Genes in Arrhythmogenic Right Ventricular Cardiomyopathy

    Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Genetic Testing and Molecular Biomarkers. 15, 4, p. 267-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population

    Christensen, A. H., Kamstrup, P. R., Gandjbakhch, E., Benn, Marianne, Jensen, J. S., Bundgård, Henning, Villard, E. & Tybjærg-Hansen, Anne, May 2016, In: European Journal of Human Genetics. 24, 5, p. 732-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2

    Christiansen, M., Hedley, P. L., Theilade, J., Stoevring, B., Leren, T. P., Eschen, O., Sørensen, K. M., Tybjærg-Hansen, Anne, Ousager, L. B., Pedersen, L. N., Frikke-Schmidt, Ruth, Aidt, F. H., Hansen, M. G., Hansen, J., Bloch Thomsen, P. E., Toft, E., Henriksen, F. L., Bundgård, Henning, Jensen, H. K. & Kanters, Jørgen K., 2014, In: BMC Medical Genetics. 15, 11 p., 31.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles

    Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles

    Christoffersen, C., Benn, M., Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Dahlbäck, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research. 53, 10, p. 2198-204 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Xanthelasmas Predict Risk of Ischemic Heart Disease, Myocardial Infarction, and Overall Death in the General Population

    Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Nordestgaard, Børge, Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 33 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  57. Published

    Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study

    Christoffersen, M., Frikke-Schmidt, R., Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: B M J. 343, p. d5497

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Polygenic risk scores: how much do they add?

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: Current Opinion in Lipidology. 32, 3, p. 157-162 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Visible Age-Related Signs and Risk of Ischemic Heart Disease in the General Population: A Prospective Cohort Study

    Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 4 Mar 2014, In: Circulation Research. 129, 9, p. 990-998 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications

    Christoffersen, M. & Tybjærg-Hansen, Anne, Jan 2016, In: Ageing Research Reviews. 25, p. 24-41 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  61. Published

    Targeting IL-6 in patients at high cardiovascular risk

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: The Lancet. 397, 10289, p. 2025-2027 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  62. Published

    Novel genes in LDL metabolism: a comprehensive overview

    Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Polygenic Risk Scores

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2022, Cardiovascular Risk Assessment in Primary Prevention. Humana Press, p. 429-446 (Contemporary Cardiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  64. Published

    Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses

    Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Mar 2017, In: Experimental Gerontology. 89, p. 69-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function

    Corbin, L. J., White, S. J., Taylor, A. E., Williams, C. M., Taylor, K., Van Den Bosch, M. T., Teasdale, J. E., Jones, M., Bond, M., Harper, M. T., Falk, L., Groom, A., Hazell, G. G. J., Paternoster, L., Munafò, M. R., Nordestgaard, B. G., Tybjærg-Hansen, A., Bojesen, S. E., Relton, C., Min, J. L. & 4 others, Davey Smith, G., Mumford, A. D., Poole, A. W. & Timpson, N. J., 2022, In: Circulation Research. 130, 3, p. 384-400 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    The European heart journal: Leading the fight to reduce the global burden of cardiovascular disease

    Crea, F., Badimon, L., Berry, C., de Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C., Tybjærg-Hansen, Anne & EHJ Editorial Board, E. E. B., 2020, In: European Heart Journal. 41, 33, p. 3113-3116 4 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  67. Published

    The European Heart Journal: fulfilling the mission

    Crea, F., Badimon, L., Berry, C., De Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C. & Tybjærg-Hansen, Anne, 2022, In: European Heart Journal. 43, 23, p. 2181-2184 4 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  68. Published

    Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

    Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nordestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjærg-Hansen, A., Watts, G. F., Averna, M., Boileau, C., Borén, J., Catapano, A. L., Defesche, J. C., Hovingh, G. K., Humphries, S. E., Kovanen, P. T. & 11 others, Masana, L., Pajukanta, P., Parhofer, K. G., Ray, K. K., Stalenhoef, A. F. H., Stroes, E., Taskinen, M., Wiegman, A., Wiklund, O., Chapman, M. J. & European Atherosclerosis Society Consensus Panel on Familial Hypercholesterolaemia, E. A. S. C. P. O. F. H., 21 Aug 2014, In: European Heart Journal. 35, 32, p. 2146-2157 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Molecular diagnosis of intermediate and severe α<inf>1</inf>-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals

    Dahl, Morten, Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, 2001, In: Clinical Chemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    ΔF508 heterozygosity in cystic fibrosis and susceptibility to asthma

    Dahl, Morten, Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 1998, In: Lancet.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Elevated plasma fibrinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary disease

    Dahl, M., Tybjærg-Hansen, Anne, Vestbo, J., Lange, Peter & Nordestgaard, Børge, 15 Sep 2001, In: American Journal of Respiratory and Critical Care Medicine. 164, 6, p. 1008-11 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

    Dahl, Morten, Vestbo, J., Zacho, J., Lange, Peter, Tybjærg-Hansen, Anne & Nordestgaard, B. G., Mar 2011, In: Thorax. 66, 3, p. 197-204

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Beta2-Adrenergic Receptor Polymorphism Associated With Reduced Lung Function In Two Large Populations

    Dahl, Morten, Thomsen, M., Nordestgaard, Børge, Sethi, A. & Tybjærg-Hansen, Anne, May 2011, C22. PATHOBIOLOGY OF COPD: LESSONS FROM INFLAMMATORY MECHANISMS AND GENOMIC STUDIES.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  74. Published

    Nose and blood pressure

    Dahl, M., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Lange, Peter & Vestbo, J., 15 Jan 2004, In: American Journal of Respiratory and Critical Care Medicine. 169, 2, p. 318; author reply 319

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

    Dahl, M., Vestbo, J., Zacho, J., Lange, Peter, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Thorax. 66, 3, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Blood pressure, risk of ischemic cerebrovascular and ischemic heart disease, and longevity in alpha(1)-antitrypsin deficiency: the Copenhagen City Heart Study

    Dahl, M., Tybjærg-Hansen, Anne, Sillesen, Henrik, Jensen, G., Steffensen, R. & Nordestgaard, Børge, 11 Feb 2003, In: Circulation. 107, 5, p. 747-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Risk of ischemic heart and ischemic cerebrovascular disease is not increased in S, Z, and 11478A alpha1-antitrypsin carriers of the Copenhagen City Heart Study

    Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Nov 2003, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 11, p. e55; author reply e55

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Morbiditet og mortalitet hos personer med mannosebindende lektinmangel. Osterbroundersøgelsen

    Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 6 Dec 2004, In: Ugeskrift for Laeger. 166, 50, p. 4606-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Baerere af cystisk fibrose har øget risiko for asthma. Osterbroundersøgelsen

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 9 Aug 1999, In: Ugeskrift for Laeger. 161, 32, p. 4507-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

    Dahl, M., Vestbo, J., Zacho, J., Lange, Peter, Tybjærg-Hansen, A., Nordestgaard, B. G., Dahl, M., Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Thorax. 66, 3, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Molecular diagnosis of intermediate and severe alpha(1)-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals

    Dahl, M., Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, Jan 2001, In: Clinical Chemistry. 47, 1, p. 56-62 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Late-breaking abstract: Glutathione-S-transferase P1 Ile105Val polymorphism associated with elevated lung function and reduced risk of lung cancer and death in 66,000 individuals

    Dahl, Morten, Norskov, M., Nordestgaard, B. & Tybjærg-Hansen, Anne, Sep 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  83. Published

    Cystic fibrosis ΔF508 heterozygotes, smoking, and reproduction: studies of 9141 individuals from a general population sample

    Dahl, M., Tybjærg-Hansen, Anne, Wittrup, H. H., Lange, Peter & Nordestgaard, Børge, 1998, In: Genomics. 50, 1, p. 89-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion

    Dahl, M., Nordestgaard, Børge, Lange, Peter & Tybjærg-Hansen, Anne, May 2001, In: Journal of Allergy and Clinical Immunology. 107, 5, p. 818-23 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease

    Dahl, M., Vestbo, J., Lange, Peter, Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2007, In: American Journal of Respiratory and Critical Care Medicine. 175, 3, p. 250-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Asthma and COPD in cystic fibrosis intron-8 5T carriers. A population-based study

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 2005, In: Respiratory Research. 6, p. 113

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease

    Dahl, Morten, Vestbo, J., Lange, Peter, Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 1 Feb 2007, In: American Journal of Respiratory and Critical Care Medicine. 175, 3, p. 250-255

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    DeltaF508 heterozygosity in cystic fibrosis and susceptibility to asthma

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 27 Jun 1998, In: Lancet. 351, 9120, p. 1911-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    A population-based study of morbidity and mortality in mannose-binding lectin deficiency

    Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 17 May 2004, In: Journal of Experimental Medicine. 199, 10, p. 1391-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Change in lung function and morbidity from chronic obstructive pulmonary disease in alpha1-antitrypsin MZ heterozygotes: A longitudinal study of the general population

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter, Vestbo, J. & Nordestgaard, Børge, 19 Feb 2002, In: Annals of Internal Medicine. 136, 4, p. 270-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Plasma TSH and cardiovascular disease in the general population: A Mendelian randomization study of 105,224 individuals

    Dalila, N., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: Atherosclerosis. 376, p. 26-33 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

    Dewey, F. E., Gusarova, V., Dunbar, R. L., O'Dushlaine, C. T., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C. V., Bruse, S., Dansky, H. M., Leader, J. B., Murray, M. F., Ritchie, M. D., Kirchner, H. L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N. & 37 others, Murphy, A. J., Hamon, S., Bouzelmat, A., Zhang, R., Shumel, B., Pordy, R., Gipe, D., Herman, G. A., Sheu, W. H., Lee, I., Liang, K., Guo, X., Rotter, J. I., Chen, Y. I., Kraus, W. E., Shah, S. H., Damrauer, S., Small, A., Rader, D. J., Wulff, A. B., Nordestgaard, Børge, Tybjærg-Hansen, Anne, van den Hoek, A. M., Princen, H. M. G., Ledbetter, D. H., Carey, D. J., Overton, J. D., Reid, J. G., Sasiela, W. J., Banerjee, P., Shuldiner, A. R., Borecki, I. B., Teslovich, T. M., Yancopoulos, G. D., Mellis, S. J., Gromada, J. & Baras, A., Jul 2017, In: New England Journal of Medicine. 377, 3, p. 211-221

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Lipid-related markers and cardiovascular disease prediction

    Di Angelantonio, E., Gao, P., Pennells, L., Kaptoge, S., Caslake, M., Thompson, A., Butterworth, A. S., Sarwar, N., Wormser, D., Saleheen, D., Ballantyne, C. M., Psaty, B. M., Sundström, J., Ridker, P. M., Nagel, D., Gillum, R. F., Ford, I., Ducimetiere, P., Kiechl, S., Koenig, W. & 31 others, Dullaart, R. P. F., Assmann, G., D'Agostino, R. B., Dagenais, G. R., Cooper, J. A., Kromhout, D., Onat, A., Tipping, R. W., Gómez-de-la-Cámara, A., Rosengren, A., Sutherland, S. E., Gallacher, J., Fowkes, F. G. R., Casiglia, E., Hofman, A., Salomaa, V., Barrett-Connor, E., Clarke, R., Brunner, E., Jukema, J. W., Simons, L. A., Sandhu, M., Wareham, N. J., Khaw, K., Kauhanen, J., Salonen, J. T., Howard, W. J., Nordestgaard, Børge, Wood, A. M., Emerging Risk Factors Collaboration, E. R. F. C. & Tybjærg-Hansen, Anne, 2012, In: J A M A: The Journal of the American Medical Association. 307, 23, p. 2499-506 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

    Do, R., Stitziel, N. O., Won, H-H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., Lange, L. A., Peloso, G. M., Auer, P. L., Girelli, D., Martinelli, N., Farlow, D. N., DePristo, M. A., Roberts, R. & 31 others, Stewart, A. F. R., Saleheen, D., Danesh, J., Epstein, S. E., Sivapalaratnam, S., Hovingh, G. K., Kastelein, J. J., Samani, N. J., Schunkert, H., Erdmann, J., Shah, S. H., Kraus, W. E., Davies, R., Nikpay, M., Johansen, C. T., Wang, J., Hegele, R. A., Hechter, E., Marz, W., Kleber, M. E., Huang, J., Johnson, A. D., Li, M., Burke, G. L., Gross, M., Liu, Y., Assimes, T. L., Heiss, G., Lange, E. M., Tybjærg-Hansen, Anne & NHLBI Exome Sequencing Project, N. E. S. P., 5 Feb 2015, In: Nature. 518, 7537, p. 102-6, 4 unpag. pages 9 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  95. Published

    Risk of cancer by ATM missense mutations in the general population

    Dombernowsky, S. L., Weischer, M., Allin, K. H., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Oncology. 26, 18, p. 3057-62 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Missense polymorphisms in BRCA1 and BRCA2 and risk of breast and ovarian cancer

    Dombernowsky, S. L., Weischer, M., Freiberg, J. J., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2009, In: Cancer Epidemiology, Biomarkers & Prevention. 18, 8, p. 2339-42 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Modifications to the Patient Rule-Induction Method that utilize non-additive combinations of genetic and environmental effects to define partitions that predict ischemic heart disease

    Dyson, G., Frikke-Schmidt, Ruth, Nordestgaard, B. G., Tybjærg-Hansen, Anne & Sing, C. F., 2009, In: Genetic Epidemiology. 33, 4, p. 317-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Blood Chimerism in Dizygotic Monochorionic Twins During 5 Years Observation

    Dziegiel, Morten Hanefeld, Hansen, M. H., Haedersdal, S., Barrett, A. N., Rieneck, K., Main, Katharina Maria, Tybjærg-Hansen, Anne & Clausen, F. B., 2017, In: American Journal of Transplantation. 17, 10, p. 2728-2732

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Risk of cancer by transferrin saturation levels and haemochromatosis genotype: population-based study and meta-analysis

    Ellervik, Christina, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Ellervik, Christina, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Internal Medicine. 271, 1, p. 51-63 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Haemochromatosis genotype and iron overload: association with hypertension and left ventricular hypertrophy

    Ellervik, Christina, Tybjærg-Hansen, Anne, Appleyard, M., Ibsen, H. & Nordestgaard, Børge, 1 Sep 2010, In: Journal of Internal Medicine. 268, 3, p. 252-64 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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