Anders Perner

Anders Perner

Clinical Professor

Member of:

  • Anaesthesiology


  1. 2024
  2. Published

    Response

    Sivapalan, P. & Perner, Anders, Feb 2024, In: Chest. 165, 2, p. e59-e60 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    Albumin use in patients with septic shock—Post-hoc analyses of an international randomised fluid trial

    Meyhoff, T. S., Granholm, A., Hjortrup, P. B., Sivapalan, P., Lange, Theis, Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander & Perner, Anders, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 3, p. 372-384 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Effects of IV fluid restriction according to site-specific intensity of standard fluid treatment-protocol

    Sivapalan, P., Kaas-Hansen, Benjamin Skov, Meyhoff, T. S., Hjortrup, P. B., Kjær, M. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, (E-pub ahead of print) In: Acta Anaesthesiologica Scandinavica. 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Effects of sceptical priors on the performance of adaptive clinical trials with binary outcomes

    Granholm, A., Lange, Theis, Harhay, M. O., Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2024, (E-pub ahead of print) In: Pharmaceutical Statistics. 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Furosemide versus placebo for fluid overload in intensive care patients-The randomised GODIF trial second version: Statistical analysis plan

    Wichmann, S., Lange, T., Perner, A., Gluud, C., Itenov, T. S., Berthelsen, R. E., Nebrich, L., Wiis, J., Brøchner, A. C., Nielsen, L. G., Behzadi, M. T., Damgaard, K., Andreasen, A. S., Strand, K., Järvisalo, M., Strøm, T., Eschen, C. T., Vang, M. L., Hildebrandt, T., Andersen, F. H. & 14 others, Sigurdsson, M. I., Thomar, K. M., Thygesen, S. K., Troelsen, T. T., Uusalo, P., Jalkanen, V., Illum, D., Sølling, C., Keus, F., Pfortmueller, C. A., Wahlin, R. R., Ostermann, M., Aneman, A. & Bestle, Morten Heiberg, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 130-136 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Heterogeneity of treatment effect of higher dose dexamethasone by geographic region (Europe vs. India) in patients with COVID-19 and severe hypoxemia – a post hoc evaluation of the COVID STEROID 2 trial

    Tirupakuzhi Vijayaraghavan, B. K., Granholm, A., Munch, M. W., Kjær, M. B. N., Møller, M. H., Perner, A., Myatra, S. N., Jha, V., Jha, V., Jha, V., Hammond, N., Micallef, S., Venkatesh, B., Hammond, N., Lange, T., Munch, M. W., Myatra, S. N., Tirupakuzhi Vijayaraghavan, B. K., Saseedharan, S., Benfield, T. & 31 others, Wahlin, R. R., Rasmussen, B. S., Andreasen, Anne Sofie, Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brøchner, A. C., Bestle, Morten Heiberg, Helleberg, Marie, Michelsen, J., Padmanaban, A., Bose, N., Møller, A., Borawake, K., Kristiansen, Klaus Tjelle, Shukla, U., Chew, M. S., Ulrik, Charlotte Suppli, Kjær, M. B. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Gluud, C., Lange, Theis, Marcussen, Klaus Vennick, Nielsen, H., Jensen, T. S., Perner, Anders & the COVID-STEROID 2 collaborators, T. C. 2. C., 2024, In: The Lancet Regional Health - Southeast Asia. 20, 8 p., 100293.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Long-term cognitive and pulmonary functions following a lower versus a higher oxygenation target in the HOT-ICU and HOT-COVID trials: A protocol update

    Crescioli, E., Riis, J. Ø., Weinreich, U. M., Jensen , Jens-Ulrik Stæhr , Poulsen, L. M., Brøchner, A. C., Lange, Theis, Perner, Anders, Klitgaard, T. L., Schjørring, O. L. & Rasmussen, B. S., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 4, p. 575-578 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium

    Mortensen, C. B., Andersen-Ranberg, N. C., Poulsen, L. M., Granholm, A., Rasmussen, B. S., Kjær, M. B. N., Lange, T., Ebdrup, B. H., Collet, M. O., Andreasen, A. S., Bestle, M. H., Uslu, B., Pedersen, H. S., Nielsen, L. G., Hästbacka, J., Jensen, T. B., Damgaard, K., Sommer, T., Morgen, M., Dey, N. & 6 others, Citerio, G., Estrup, S., Egerod, Ingrid Eugenie, Samuelson, K., Perner, Anders & Mathiesen, Ole, 2024, In: Intensive Care Medicine. 50, p. 103–113 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial

    Nielsen, F. M., Klitgaard, T. L., Siegemund, M., Laake, J. H., Thormar, K. M., Cole, J. M., Aagaard, S. R., Bunzel, A-M. G., Vestergaard, S. R., Langhoff, P. K., Pedersen, C. H., Hejlesen, J. Ø., Abdelhamid, S., Dietz, A., Gebhard, C. E., Zellweger, N., Hollinger, A., Poulsen, L. M., Weihe, S., Andersen-Ranberg, N. C. & 25 others, Pedersen, U. G., Mathiesen, O., Andreasen, Anne Sofie, Brix, H., Thomsen, J. J., Petersen, C. H., Bestle, Morten Heiberg, Wichmann, S., Lund, M. S., Mortensen, K. M., Brand, B. A., Haase, N., Iversen, S. A., Marcussen, Klaus Vennick, Brøchner, A. C., Borup, M., Grøfte, T., Hildebrandt, T., Kjær, M. N., Engstrøm, J., Lange, Theis, Perner, Anders, Schjørring, O. L., Rasmussen, B. S. & HOT-COVID Trial Group, H. T. G., 2024, In: JAMA. 331, 14, p. 1185-1194 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Platelet transfusions in adult thrombocytopenic ICU patients: Protocol for a sub-study of the PLOT-ICU cohort

    Anthon, C. T., Pène, F., Perner, Anders, Azoulay, E., Puxty, K., Van De Louw, A., Chawla, S., Castro, P., Povoa, P., Coelho, L., Metaxa, V., Kochanek, M., Liebregts, T., Kander, T., Sivula, M., Møller, Morten Hylander & Russell, Lene, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 3, p. 434-440 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock—Bayesian analyses of the CLASSIC trial

    Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Kaas-Hansen, Benjamin Skov, Kjær, M. B. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 2, p. 236-246 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2023
  14. Published

    Non-response for health-related quality of life outcomes in ICU patients: A systematic review of the reporting in randomised trials

    Kjær, M. B. N., Madsen, M. B., Meier, N., Granholm, A., Møller, Morten Hylander, Egerod, Ingrid Eugenie & Perner, Anders, Aug 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 842-852 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Abnormal serum levels of magnesium, phosphate, and zinc in ICU patients—Characteristics, management, and outcomes: The WhyTrace cohort study

    Vesterlund, G. K., Thorsen-Meyer, H. C., Møller, Morten Hylander, Brunak, Søren, Strøm, T., Perner, Anders & Kaas-Hansen, Benjamin Skov, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 925-935 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Albumin administration in septic shock-Protocol for post-hoc analyses of data from a multicentre RCT

    Meyhoff, T. S., Granholm, A., Hjortrup, P. B., Sivapalan, P., Lange, Theis, Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 8, p. 1128-1136 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    An overview of methodological considerations regarding adaptive stopping, arm dropping and randomisation in clinical trials

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Schjørring, O. L., Andersen, L. W., Perner, Anders, Jensen, Aksel Karl Georg & Møller, Morten Hylander, 2023, In: Journal of Clinical Epidemiology. 153, p. 45-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Association between days alive without life support/out of hospital and health-related quality of life

    Granholm, A., Schjorring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strom, T., Lange, Theis, Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 762-771 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Associations between enteral nutrition and outcomes in the SUP-ICU trial: Protocol for exploratory post hoc analyses

    Borthwick, M., Granholm, A., Marker, S., Krag, M., Lange, Theis, Wise, M. P., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Wetterslev, J., Perner, Anders, Møller, Morten Hylander & SUP-ICU investigators, S. I., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 481-486 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Atrial Fibrillation (AFIB) in the ICU: Incidence, Risk Factors, and Outcomes: The International AFIB-ICU Cohort Study

    Wetterslev, M., Hylander Møller, M., Granholm, A., Hassager, C., Haase, N., Lange, T., Myatra, S. N., Hästbacka, J., Arabi, Y. M., Shen, J., Cronhjort, M., Lindqvist, E., Aneman, A., Young, P. J., Szczeklik, W., Siegemund, M., Koster, T., Aslam, T. N., Bestle, M. H., Girkov, M. S. & 31 others, Kalvit, K., Mohanty, R., Mascarenhas, J., Pattnaik, M., Vergis, S., Haranath, S. P., Shah, M., Joshi, Z., Wilkman, E., Reinikainen, M., Lehto, P., Jalkanen, V., Pulkkinen, A., An, Y., Wang, G., Huang, L., Huang, B., Liu, W., Gao, H., Dou, L., Li, S., Yang, W., Tegnell, E., Perner, Anders, Poulsen, L. M., Hildebrandt, T., Andreasen, Anne Sofie, Kristiansen, Klaus Tjelle, Mohr, T., Møller, Kirsten & the AFIB-ICU collaborators, T. A. C., 2023, In: Critical Care Medicine. 51, 9, p. 1124-1137 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia

    Blette, B. S., Granholm, A., Li, F., Shankar-Hari, M., Lange, Theis, Munch, M. W., Møller, Morten Hylander, Perner, Anders & Harhay, M. O., 2023, In: Scientific Reports. 13, 1, 10 p., 6570.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Clinical progression, disease severity, and mortality among adults hospitalized with COVID-19 caused by the Omicron and Delta SARS-CoV-2 variants: A population-based, matched cohort study

    Harboe, Z. B., Roed, C., Holler, J. G., Khan, F. I., Abdulrahman, A. N. A., Mulverstedt, S. L., Lindgaard-Jensen, B., Bertelsen, B. B., Søborg, C., Nielsen, T. L., Hansen, L. V., Madsen, B. L., Browatzki, A., Eiberg, M., Bernhard, P. H., Pedersen, E. M. J., Egelund, G. B., Dungu, A. M., Sejdic, A., Mathiesen, I. H. M. & 56 others, Jespersen, N. Z., Petersen, P. T., Nielsen, L., Jepsen, M. P. G., Pedersen, T. I., Eriksson, R., Seitz-Rasmussen, H. E. S., Bestle, Morten Heiberg, Andersen, H., Skram, U., Skøtt, M. R., Altaraihi, S., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Bagge, K., Jørgensen, K. M., Knudsen, M. J. S., Leineweber, T., Schneider, Uffe Vest, Ahlstrom, M. G., Rytter, S., Le Dous, N., Ravn, P., Reiter, N., Podlekareva, D., Knudsen, A., Johnsen, Stine, Kristensen, Lars Erik Vølund, Leding, C., Hertz, B. B., Benfield, Thomas, Kirk, Ole, Holler, J. G., Ostrowski, Sisse Rye, Sigurdsson, S. T., Perner, Anders, Kirkby, N., Pedersen, M. S., Van Wijhe, M., Simonsen, L., Bager, P. M., Krause, T. G., Voldstedlund, M., Christiansen, L. E., Stegger, M., Cohen, A., Fonager, J., Fomsgaard, A., Legarth, R., Rasmussen, M., Gubbels, S., Wohlfahrt, J., Lillebaek, Troels, Johannesen, C. K., Van Wijhe, M. & Fischer, Thea Kølsen, 2023, In: PLoS ONE. 18, 4 , 15 p., e0282806.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Dexmedetomidine for the prevention of delirium in adults admitted to the intensive care unit or post-operative care unit: A systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis

    Maagaard, M., Barbateskovic, M., Andersen-Ranberg, N. C., Kronborg, J. R., Chen, Y. X., Xi, H. H., Perner, Anders & Wetterslev, J., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 382-411 30 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

    the European Society of Intensive Care Medicine Taskforce on ARDS, T. E. S. O. I. C. M. T. O. A., 2023, In: Intensive Care Medicine. 49, 7, p. 727-759 33 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of 12 mg vs. 6 mg dexamethasone on thromboembolism and bleeding in patients with critical COVID-19 - a post hoc analysis of the randomized, blinded COVID STEROID 2 trial

    Jonmarker, S., Alarcón, F., Litorell, J., Granholm, A., Alm, E. J., Chew, M., Russell, Lene, Weihe, S., Madsen, Emilie, Meier, N., Leistner, J. W., Mårtensson, J., Hollenberg, J., Perner, Anders, Kjær, M. B. N., Munch, M. W., Dahlberg, M., Cronhjort, M. & Wahlin, R. R., 2023, In: Annals of Intensive Care. 13, 1, 10 p., 12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effects of duration of follow-up and lag in data collection on the performance of adaptive clinical trials

    Granholm, A., Lange, Theis, Harhay, M. O., Jensen, Aksel Karl Georg, Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2023, In: Pharmaceutical Statistics. 23, 2, p. 138-150 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effects of magnesium, phosphate, or zinc supplementation in intensive care unit patients—A systematic review and meta-analysis

    Vesterlund, G. K., Jensen, T. S., Ellekjaer, K. L., Møller, Morten Hylander, Thomsen, Thordis & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 3, p. 264-276

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Functional and cognitive rehabilitation interventions during intensive care admission: A protocol for a systematic integrative review

    Collet, Marie Oxenbøll, Laerkner, E., Jensen, J., Egerod, Ingrid Eugenie, Christensen, Jan, Jørgensen, N. K., Kjærgaard, R. S., Olausson, S., Wøien, H., Lange, Theis, Nielsen, A. H., Kjær, M. B. N., Bruun, C. R. L. & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 5, p. 670-674 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Goal-directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A randomised, blinded trial (GODIF trial—First version)

    Wichmann, S., Schønemann-Lund, M., Perner, Anders, Itenov, Theis Skovsgaard, Lange, Theis, Gluud, C., Berthelsen, R. E., Brøchner, A. C., Wiis, J. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 470-478 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Haloperidol for the treatment of delirium in critically ill patients: an updated systematic review with meta-analysis and trial sequential analysis

    Andersen-Ranberg, N. C., Barbateskovic, M., Perner, Anders, Collet, Marie Oxenbøll, Musaeus Poulsen, L., van der Jagt, M., Smit, L., Wetterslev, J., Mathiesen, Ole & Maagaard, M., 2023, In: Critical Care. 27, 1, 14 p., 329.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID–ICU trial

    Andersen-Ranberg, N. C., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M., Citerio, G., Collet, Marie Oxenbøll, Weber, S. O., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2023, In: Intensive Care Medicine. 49, p. 411–420 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Health-related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study

    Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Møller, Morten Hylander, Jensen, Aksel Karl Georg, Larsen, M. E., Cuthbertson, B. H., Perner, Anders & Granholm, A., 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Heterogeneous treatment effects of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia—Post hoc exploratory analyses of the COVID STEROID 2 trial

    Granholm, A., Munch, M. W., Andersen-Ranberg, N., Myatra, S. N., Vijayaraghavan, B. K. T., Venkatesh, B., Jha, V., Wahlin, R. R., Jakob, S. M., Cioccari, L., Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 2, p. 195-205 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Issuing of isotonic crystalloid solutions to Danish public hospitals in 2021—A retrospective nationwide observational study

    Ellekjaer, K. L., Perner, Anders, Bruun Svan, K. & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 2, p. 177-184 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock

    Kjær, M. B. N., Meyhoff, T. S., Sivapalan, P., Granholm, A., Hjortrup, P. B., Madsen, M. B., Møller, M. H., Egerod, I., Wetterslev, J., Lange, T., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Ostermann, M., Gould, D., Cecconi, M., Malbrain, M. L. N. G., Ahlstedt, C., Kiel, L. B. & 41 others, Bestle, Morten Heiberg, Nebrich, L., Hildebrandt, T., Russell, Lene, Vang, M., Rasmussen, M. L., Sølling, C., Brøchner, A. C., Krag, M., Pfortmueller, C., Kriz, M., Siegemund, M., Albano, G., Aagaard, S. R., Bundgaard, H., Crone, V., Wichmann, S., Johnstad, B., Martin, Y. K., Seidel, P., Mårtensson, J., Hollenberg, J., Wistrand, M., Donati, A., Barbara, E., Karvunidis, T., Hollinger, A., Carsetti, A., Lumlertgul, N., Joelsson-Alm, E., Lambiris, N., Aslam, T. N., Friberg, F. F., Vesterlund, G. K., Mortensen, C. B., Vestergaard, S. R., Caspersen, S. F., Jensen, D. B., Borup, M., Rasmussen, B. S. & Perner, Anders, 2023, In: Intensive Care Medicine. 49, p. 820–830 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Long-term outcomes in COVID-19 patients admitted to intensive care in Denmark: A nationwide observational study

    Meier, N., Perner, A., Plovsing, R., Christensen, S., Poulsen, L. M., Brøchner, A. C., Rasmussen, B. S., Helleberg, M., Jensen, J. U. S., Andersen, L. P. K., Siegel, H., Ibsen, M., Jørgensen, V. L., Winding, R., Iversen, S., Pedersen, H. P., Sølling, C., Garcia, R. S., Michelsen, J., Mohr, T. & 16 others, Michagin, G., Espelund, U. S., Bundgaard, H., Kirkegaard, L., Smitt, M., Sigurdsson, S., Buck, D. L., Ribergaard, N., Pedersen, H. S., Toft, M. H., Jonassen, T. B., Mølgaard Nielsen, F., Madsen, E. K., Haberlandt, T. N., Bredahl, L. S. & Haase, N., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 9, p. 1239-1248 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Lower versus higher oxygenation targets in hypoxaemic ICU patients after cardiac arrest

    Crescioli, E., Lass Klitgaard, T., Perner, Anders, Lilleholt Schjørring, O. & Steen Rasmussen, B., 2023, In: Resuscitation. 188, 109838.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Patient and public involvement in contemporary large intensive care trials: A meta-epidemiological study

    Estrup, S., Barot, E., Mortensen, C. B., Anthon, C. T., Crescioli, E., Kjær, M. B. N., Vesterlund, G. K., Bruun, C. R. L., Collet, Marie Oxenbøll, Rasmussen, B. S., Sivapalan, P., Poulsen, L. M., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 3, p. 256-263 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Piperacillin/tazobactam versus carbapenems in patients with severe bacterial infections: A systematic review with meta-analysis

    Munch, M. W., Granholm, A., Jonsson, A. B., Sjövall, F., Helleberg, Marie, Hertz, Frederik Boëtius, Andersen, J. S., Steensen, M., Achiam, Michael Patrick, Perner, Anders & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Platform trials: Platformsforsøg

    Perner, A., Kjær, M. B. N., Thorsen-Meyer, H. C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. R., Jensen, A. K., Lange, T., Albertsen, T., Pedersen, C. D., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., Rasmussen, B. S., Schjørring, O. L., Maagaard, M. & 2 others, Møller, Morten Hylander & Granholm, A., 2023, In: Ugeskrift for Laeger. 185, 41, 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Protocol for a systematic review and meta-analysis assessing conservative versus liberal intravenous fluid administration in patients with sepsis or septic shock at risk of fluid overload

    Bharwani, A., Pérez, M. L., Englesakis, M., Meyhoff, T. S., Perner, Anders, Sivapalan, P. & Wilcox, M. E., 2023, In: BMJ Open. 13, 5, 4 p., e069601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Real-world causal evidence for planned predictive enrichment in critical care trials: A scoping review

    Kaas-Hansen, Benjamin Skov, Granholm, A., Sivapalan, P., Anthon, C. T., Schjørring, O. L., Maagaard, M., Kjaer, M. N., Mølgaard, J., Ellekjaer, K. L., Fagerberg, S. K., Lange, Theis, Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 16-25 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Routine Versus On-Demand Blood Sampling in Critically Ill Patients: A Systematic Review∗

    Hjortso, C. J. S., Møller, Morten Hylander, Perner, Anders & Brochner, A. C., 2023, In: Critical Care Medicine. 51, 6, p. 717-730 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)

    Anthon, C. T., Pène, F., Perner, A., Azoulay, E., Puxty, K., Van De Louw, A., Barratt-Due, A., Chawla, S., Castro, P., Póvoa, P., Coelho, L., Metaxa, V., Kochanek, M., Liebregts, T., Kander, T., Hästbacka, J., Andreasen, J. B., Péju, E., Nielsen, L. B., Hvas, C. L. & 101 others, Dufranc, E., Canet, E., Lundqvist, L., Wright, C. J., Schmidt, J., Uhel, F., Ait-Oufella, H., Krag, M., Cos Badia, E., Díaz-Lagares, C., Menat, S., Voiriot, G., Clausen, N. E., Lorentzen, K., Kvåle, R., Hildebrandt, T., Holten, A. R., Strand, K., Tzalavras, A., Bestle, Morten Heiberg, Klepstad, P., Fernandez, S., Vimpere, D., Costa, C., Graça, C., Lueck, C., Juhl, C. S., Costa, C., Bådstøløkken, P. M., Miranda, T., Lêdo, L. S. A., Sousa Torres, J. C., Granholm, A., Møller, Morten Hylander, Russell, Lene, Khalil, A., Yehia, A., Salem, H., Farahat, H., Sudevan, M., Biggart, M., Fatima, N., Elkhonezy, M., Bunzel, A. M., Siegumfeldt, R. M., Vestergaard, S. R., Pelle, J., Lê, M. P., Vigneron, C., Bertrix, M., Cirera, P., Laghlam, D., Bredin, S., Marin, N., Toppenberg, M., Benelli, B., Seguin, A., Garret, C., Guillotin, F., Blonz, G., Lascarrou, J. B., Lemarie, J., Desmedt, L., Agbakou, M., Carpentier, M., Martin, M., Benkalfate, N., Zambon, O., Decamps, P., Wilquin, P. L., Benguerfi, S., Gardner, J., Remor, N., Carr, S., Yang, G., Gernez, C., Thiry, I., Missri, L., Denneborg, M. K. G., Brown, K., Casares, V., Sivula, M., Lappi, E., Pettilä, L., Heinonen, J., Saario, M., Mecheri, M. K., Elabbadi, A., Desnos, C., Lafarge, A., Mghirbi, O., Sjøbø, B., Christoffersen, C., Bestle, F. H., Lemos, C., Gonçalves, C. V., Jacinto, N. M. B., Anselmo, M. P., Hoeper, M. M., Hoff, M. & Simões Freire, P. M., 2023, In: Intensive Care Medicine. 49, 11, p. 1327-1338 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Thromboembolic and bleeding events in ICU patients with COVID-19: A nationwide, observational study

    Russell, L., Weihe, S., Madsen, E. K., Hvas, C. L., Leistner, J. W., Michelsen, J., Brøchner, A. C., Bastiansen, A., Mølgaard Nielsen, F., Meier, N., Andreasen, A. S., Ribergaard, NE., Rasmussen, B. S., Sølling, C. G., Buck, D. L., Bundgaard, H., Pedersen, H. S., Darfelt, I. S., Poulsen, L. M., Ibsen, M. & 9 others, Plovsing, Ronni Thermann Reitz, Sigurdsson, S. T., Iversen, S., Hildebrandt, T., Mohr, T., Espelund, U. S., Jørgensen, Vibeke Renée Lind, Haase, N. & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 1, p. 76-85 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Munch, M. W., Harhay, M. O., Zampieri, F. G., Perner, Anders, Møller, Morten Hylander & Jensen, Aksel Karl Georg, 2023, In: BMC Medical Research Methodology. 23, 1, 12 p., 139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Use of prokinetic agents in hospitalised adult patients: a scoping review

    Crone, V., Møller, Morten Hylander, Bækgaard, E. S., Perner, Anders, Bytzer, Peter, Alhazzani, W. & Krag, M., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 5, p. 588-598

    Research output: Contribution to journalReviewResearchpeer-review

  48. 2022
  49. Published

    Causal inference for planning randomised critical care trials: protocol for a scoping review

    Kaas-Hansen, Benjamin Skov, Granholm, A., Anthon, C. T., Kjær, M. N., Sivapalan, P., Maagaard, M., Schjørring, O. L., Fagerberg, S. K., Ellekjær, K. L., Mølgaard, J., Ekstrøm, Claus Thorn, Møller, Morten Hylander & Perner, Anders, Oct 2022, In: Acta Anaesthesiologica Scandinavica. 66, 10, p. 1274–1278 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published
  51. Published

    Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients (REFACED Sepsis)-protocol for a multicenter, randomized, clinical, proof-of-concept trial

    Jessen, M. K., Andersen, L. W., Thomsen, M. H., Kristensen, P., Hayeri, W., Hassel, R. E., Perner, Anders, Petersen, J. A. K. & Kirkegaard, H., 29 Mar 2022, In: Pilot and Feasibility Studies. 8, 1, 8 p., 75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries

    Chew, M. S., Kattainen, S., Haase, N., Buanes, E. A., Kristinsdottir, L. B., Hofsø, K., Laake, J. H., Kvåle, R., Hästbacka, J., Reinikainen, M., Bendel, S., Varpula, T., Walther, S., Perner, Anders, Flaatten, H. K. & Sigurdsson, M. I., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 56-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Acetate- versus lactate-buffered crystalloid solutions: A systematic review with meta-analysis and trial sequential analysis

    Ellekjaer, K. L., Perner, Anders, Sivapalan, P. & Møller, Morten Hylander, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 7, p. 782-794

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    Agents intervening against delirium in the intensive care unit trial — Protocol for a secondary Bayesian analysis

    Andersen-Ranberg, N., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M. P. G., Citerio, G., Oxenbøll-Collet, M., Weber, S., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. B. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 7, p. 898-903

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Changes over time in characteristics, resource use and outcomes among ICU patients with COVID-19—A nationwide, observational study in Denmark

    Haase, N., Plovsing, R., Christensen, S., Poulsen, L. M., Brøchner, A. C., Rasmussen, B. S., Helleberg, M., Jensen, J. U. S., Andersen, L. P. K., Siegel, H., Ibsen, M., Jørgensen, V. L., Winding, R., Iversen, S., Pedersen, H. P., Madsen, J., Sølling, C., Garcia, R. S., Michelsen, J., Mohr, T. & 19 others, Michagin, G., Espelund, U. S., Bundgaard, H., Kirkegaard, L., Smitt, M., Buck, D. L., Ribergaard, N. E., Pedersen, H. S., Christensen, B. V., Nielsen, L. P., Clapp, E., Jonassen, T. B., Weihe, S., la Cour, K., Nielsen, F. M., Madsen, E. K., Haberlandt, T. N., Meier, N. & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 8, p. 987-995 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Choice of priors: how much scepticism is appropriate?

    Granholm, A., Munch, M. W., Møller, Morten Hylander, Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, p. 372–373 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  57. Published

    Conservative vs. liberal fluid therapy in septic shock - Protocol for secondary Bayesian analyses of the CLASSIC trial

    Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Møller, Morten Hylander, Perner, Anders & Granholm, A., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 6, p. 767-771 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Design considerations in clinical trials with adaptive stopping, arm-dropping and randomisation

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, T., Schjorring, O., Andersen, L., Perner, Anders, Jensen, A. & Møller, M., 2022, p. S88-S89. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  59. Published

    Development of a core outcome set for general intensive care unit patients - A protocol

    Kjær, M. N., Granholm, A., Vesterlund, G. K., Estrup, S., Sivapalan, P., Bruun, C. R. L., Mortensen, C. B., Poulsen, L. M., Møller, Morten Hylander, Christensen, S., Strøm, T., Laerkner, E., Brøchner, A. C., Rasmussen, B. S., Vestergaard, S. R., Barot, E., Madsen, M. B., Egerod, Ingrid Eugenie, Perner, Anders & Collet, M. O., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 3, p. 415-424 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Development of a core outcome set for general intensive care unit patients - Need for a broader context - Author's reply

    Kjær, M. N., Granholm, A., Perner, Anders & Collet, M. O., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 541-542 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  61. Published

    Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial

    Granholm, A., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Kjaer, M-B. N., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Moller, M. H., Benfield, T., Venkatesh, B., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, V. & 26 others, Kristiansen, Klaus Tjelle, Ulrik, Charlotte Suppli, Jorgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brochner, A. C., Strom, T., Moller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Wamberg, C. A., Gluud, C., Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, p. 45–55 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Dexamethasone and Number of Days Alive Without Life Support in Adults with COVID-19 and Severe Hypoxemia - Reply

    Munch, M. W., Granholm, A. & Perner, Anders, 2022, In: JAMA - Journal of the American Medical Association. 327, 7, p. 683 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  63. Published

    Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data

    Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, A. B., Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Goal directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A trial protocol for a randomised, blinded trial (GODIF trial)

    Wichmann, S., Itenov, T. S., Berthelsen, R. E., Lange, T., Perner, A., Gluud, C., Lawson-Smith, P., Nebrich, L., Wiis, J., Brøchner, A. C., Hildebrandt, T., Behzadi, M. T., Strand, K., Andersen, F. H., Strøm, T., Järvisalo, M., Damgaard, K. A. J., Vang, M. L., Wahlin, R. R., Sigurdsson, M. I. & 4 others, Thormar, K. M., Ostermann, M., Keus, F. & Bestle, Morten Heiberg, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 9, p. 1138-1145 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Haloperidol for the Treatment of Delirium in ICU Patients

    Andersen-Ranberg, N. C., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Haestbacka, J., Morgan, M., Citerio, G., Caballero, J., Lange, T., Kjaer, M-B. N., Ebdrup, B. H., Engstrom, J., Olsen, M. H., Oxenboll Collet, M., Mortensen, C. B., Weber, S-O., Andreasen, A. S., Bestle, M. H., Uslu, B. & 28 others, Scharling Pedersen, H., Gramstrup Nielsen, L., Toft Boesen, H. C., Jensen, J. V., Nebrich, L., La Cour, K., Laigaard, J., Haurum, C., Olesen, M. W., Overgaard-Steensen, C., Westergaard, B., Brand, B. A., Kingo Vesterlund, G., Thornberg Kyhnauv, P., Mikkelsen, V. S., Hyttel-Sorensen, S., de Haas, I., Aagaard, S. R., Nielsen, L. O., Eriksen, A. S., Rasmussen, B. S., Brix, H., Hildebrandt, T., Schonemann-Lund, M., Fjeldsoe-Nielsen, H., Kuivalainen, A., Mathiesen, Ole & AID ICU Trial Grp, 2022, In: New England Journal of Medicine. 387, 20, p. 2425-2435 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Health-related quality of life and days alive without life support or out of hospital: protocol

    Granholm, A., Schjørring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strøm, T., Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 2, p. 295-301 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Higher versus lower oxygenation targets in COVID-19 patients with severe hypoxaemia (HOT-COVID) trial: Protocol for a secondary Bayesian analysis

    Mølgaard Nielsen, F., Lass Klitgaard, T., Granholm, A., Lange, Theis, Perner, Anders, Lilleholt Schjørring, O. & Steen Rasmussen, B., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 3, p. 408-414

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method

    Nasa, P., Azoulay, E., Chakrabarti, A., Divatia, J. V., Jain, R., Rodrigues, C., Rosenthal, V. D., Alhazzani, W., Arabi, Y. M., Bakker, J., Bassetti, M., De Waele, J., Dimopoulos, G., Du, B., Einav, S., Evans, L., Finfer, S., Guérin, C., Hammond, N. E., Jaber, S. & 23 others, Kleinpell, R. M., Koh, Y., Kollef, M., Levy, M. M., Machado, F. R., Mancebo, J., Martin-Loeches, I., Mer, M., Niederman, M. S., Pelosi, P., Perner, Anders, Peter, J. V., Phua, J., Piquilloud, L., Pletz, M. W., Rhodes, A., Schultz, M. J., Singer, M., Timsit, J. F., Venkatesh, B., Vincent, J. L., Welte, T. & Myatra, S. N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e74-e87

    Research output: Contribution to journalReviewResearchpeer-review

  69. Published

    Interactions in clinical trials: Protocol and statistical analysis plan for an explorative study of four randomized ICU trials on use of pantoprazole, oxygenation targets, haloperidol and intravenous fluids

    Schjørring, O. L., Lange, Theis, Krag, M., Andersen-Ranberg, N. C., Meyhoff, T. S., Marker, S., Klitgaard, T. L., Estrup, S., Møller, Morten Hylander, Rasmussen, B. S., Poulsen, L. M. & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 156-162 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Long-term cognitive and functional status in Danish ICU patients with COVID-19

    Weihe, S., Mortensen, C. B., Haase, N., Andersen, L. P. K., Mohr, T., Siegel, H., Ibsen, M., Jørgensen, V. R. L., Buck, D. L., Pedersen, H. B. S., Pedersen, H. P., Iversen, S., Ribergaard, N., Rasmussen, B. S., Winding, R., Espelund, U. S., Bundgaard, H., Sølling, C. G., Christensen, S., Garcia, R. S. & 7 others, Brøchner, A. C., Michelsen, J., Michagin, G., Kirkegaard, L., Perner, Anders, Mathiesen, Ole & Poulsen, L. M., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 8, p. 978-986 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Long-term cognitive and pulmonary functions following a lower versus a higher oxygenation target in the HOT-ICU trial: protocol and statistical analysis plan

    Crescioli, E., Riis, J., Weinreich, U. M., Jensen , Jens-Ulrik Stæhr , Poulsen, L. M., Brøchner, A. C., Lange, Theis, Perner, Anders, Klitgaard, T. L., Schjørring, O. L. & Rasmussen, B. S., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 2, p. 282-287 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Long-term mortality and health-related quality of life in the COVID STEROID trial

    Munch, M. W., Granholm, A., Kjær, M. N., Aksnes, T. S., Sølling, C. G., Christensen, S. & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 543-545 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  73. Published

    Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia

    Crescioli, E., Klitgaard, T. L., Poulsen, L. M., Brand, B. A., Siegemund, M., Grøfte, T., Keus, F., Pedersen, U. G., Bäcklund, M., Karttunen, J., Morgan, M., Ciubotariu, A., Bunzel, A-M. G., Vestergaard, S. R., Jensen, N. M., Jensen, T. S., Kjær, M-B. N., Jensen, A. K. G., Lange, T., Wetterslev, J. & 3 others, Perner, Anders, Schjørring, O. L. & Rasmussen, B. S., 2022, In: Intensive Care Medicine. 48, 6, p. 714–722 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia

    Granholm, A., Kjær, M-B. N., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Møller, M. H., Benfield, T., Venkatesh, B., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, V. & 29 others, Kristiansen, Klaus Tjelle, Ulrik, Charlotte Suppli, Jørgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brochner, A. C., Strøm, T., Møller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Wamberg, C. A., Bose, N., Shah, M. S., Darfelt, I. S., Gluud, C., Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, 5, p. 580–589 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Loop diuretics in adult intensive care patients with fluid overload: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

    Wichmann, S., Barbateskovic, M., Liang, N., Itenov, Theis Skovsgaard, Berthelsen, R. E., Lindschou, J., Perner, Anders, Gluud, C. & Bestle, Morten Heiberg, 2022, In: Annals of Intensive Care. 12, 1, 16 p., 52.

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    Lower versus higher oxygenation targets in critically ill patients with severe hypoxaemia: secondary Bayesian analysis to explore heterogeneous treatment effects in the Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU) trial

    Klitgaard, T. L., Schjørring, O. L., Lange, Theis, Møller, Morten Hylander, Perner, Anders, Rasmussen, B. S. & Granholm, A., 2022, In: British Journal of Anaesthesia. 128, 1, p. 55-64 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Oxygenation targets in ICU patients with COVID-19: a post-hoc sub-group analysis of the HOT-ICU trial

    Rasmussen, B. S., Klitgaard, T. L., Perner, A., Brand, B. A., Hildebrandt, T., Siegemund, M., Hollinger, A., Aagaard, S. R., Bestle, M. H., Marcussen, K. V., Brøchner, A. C., Sølling, C. G., Poulsen, L. M., Laake, J. H., Aslam, T. N., Bäcklund, M., Okkonen, M., Morgan, M., Sharman, M., Lange, T. & 2 others, Wetterslev, J. & Schjørring, O. L., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 76-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review

    Granholm, A., Anthon, C. T., Kjær, M. N., Maagaard, M., Kaas-Hansen, Benjamin Skov, Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2022, In: Critical Care Medicine. 50, 10, p. e759-e771 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  79. Published

    Platelet transfusions and thrombocytopenia in intensive care units: Protocol for an international inception cohort study (PLOT-ICU)

    Anthon, C. T., Pène, F., Perner, Anders, Azoulay, E., Puxty, K., Van De Louw, A., Barratt-Due, A., Chawla, S., Castro, P., Povoa, P., Coelho, L., Metaxa, V., Munshi, L., Kochanek, M., Liebregts, T., Kander, T., Hästbacka, J., Møller, Morten Hylander, Russell, Lene & PLOT-ICU Investigators and the Nine-I Study Group, P. I. A. T. N. S. G., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 9, p. 1146-1155 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Prophylactic platelet transfusions versus no prophylaxis in hospitalized patients with thrombocytopenia: A systematic review with meta‐analysis

    Anthon, C. T., Granholm, A., Sivapalan, P., Zellweger, N., Pène, F., Puxty, K., Perner, Anders, Møller, Morten Hylander & Russell, Lene, 2022, In: Transfusion. 62, 10, p. 2117-2136

    Research output: Contribution to journalReviewResearchpeer-review

  81. Published

    Prostacyclin in Mechanically Ventilated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized, Clinical Trial

    Johansson, P. I., Søe-Jensen, P., Bestle, Morten Heiberg, Clausen, N. E., Kristiansen, Klaus Tjelle, Lange, Theis, Stensballe, J. & Perner, Anders, 2022, In: American Journal of Respiratory and Critical Care Medicine. 205, 3, p. 324-329 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Public versus patient health preferences: Protocol for a study to elicit EQ-5D-5L health state valuations for patients who have survived a stay in intensive care

    Halling, C. M. B., Gudex, C., Perner, Anders, Jensen, C. E. & Gyrd-Hansen, D., 2022, In: BMJ Open. 12, 5, e058500.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Randomised clinical trials in critical care: past, present and future

    Granholm, A., Alhazzani, W., Derde, L. P. G., Angus, D. C., Zampieri, F. G., Hammond, N. E., Sweeney, R. M., Myatra, S. N., Azoulay, E., Rowan, K., Young, P. J., Perner, Anders & Møller, Morten Hylander, 2022, In: Intensive Care Medicine. 48, 2, p. 164-178

    Research output: Contribution to journalReviewResearchpeer-review

  84. Published

    Restriction of Intravenous Fluid in ICU Patients with Septic Shock

    Meyhoff, T. S., Hjortrup, P. B., Wetterslev, J., Sivapalan, P., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M., Pettila, V., Møller, M. H., Kjaer, M-B. N., Lange, T., Overgaard-Steensen, C., Brand, B. A., Winther-Olesen, M., White, J. O., Quist, L. & 48 others, Westergaard, B., Jonsson, A. B., Hjortso, C. J. S., Meier, N., Jensen, T. S., Engstrom, J., Nebrich, L., Andersen-Ranberg, N. C., Jensen, J. V., Joseph, N. A., Poulsen, L. M., Herlov, L. S., Solling, C. G., Pedersen, S. K., Knudsen, K. K., Straarup, T. S., Vang, M. L., Bundgaard, H., Rasmussen, B. S., Aagaard, S. R., Hildebrandt, T., Russell, Lene, Bestle, Morten Heiberg, Schonemann-Lund, M., Brochner, A. C., Elvander, C. F., Hoffmann, S. K. L., Rasmussen, M. L., Martin, Y. K., Friberg, F. F., Seter, H., Aslam, T. N., Adnoy, S., Seidel, P., Strand, K., Johnstad, B., Joelsson-Alm, E., Christensen, J., Ahlstedt, C., Pfortmueller, C. A., Siegemund, M., Greco, M., Radej, J., Kriz, M., Gould, D. W., Rowan, K. M., Mouncey, P. R. & Perner, Anders, 2022, In: New England Journal of Medicine. 386, p. 2459-2470 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Restriction of Intravenous Fluid in ICU Patients with Septic Shock. Reply

    Meyhoff, T. S., Sivapalan, P. & Perner, Anders, 2022, In: The New England Journal of Medicine. 387, 9, p. 857 1 p.

    Research output: Contribution to journalComment/debateResearch

  86. Published

    Restrictive fluids versus standard care in adults with sepsis in the emergency department (REFACED): A multicenter, randomized feasibility trial

    Jessen, M. K., Andersen, L. W., Thomsen, M. H., Kristensen, P., Hayeri, W., Hassel, R. E., Messerschmidt, T. G., Sølling, C. G., Perner, Anders, Petersen, J. A. K. & Kirkegaard, H., 2022, In: Academic Emergency Medicine. 29, 10, p. 1172-1184 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    The effect of prostacyclin infusion on markers of endothelial activation and damage in mechanically ventilated patients with SARS-CoV-2 infection

    Vigstedt, M., Søe-Jensen, P., Bestle, Morten Heiberg, Clausen, N. E., Kristiansen, Klaus Tjelle, Lange, Theis, Stensballe, J., Perner, Anders & Jo­hans­son, Pär In­ge­mar , 2022, In: Journal of Critical Care. 69, 154010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial

    Halling, C. M. B., Møller, Morten Hylander, Marker, S., Krag, M., Kjellberg, J., Perner, Anders & Gyrd-Hansen, D., 2022, In: Intensive Care Medicine. 48, 4, p. 426-434

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Transfusion practice in the bleeding critically ill: An international online survey—The TRACE-2 survey

    de Bruin, S., Eggermont, D., van Bruggen, R., de Korte, D., Scheeren, T. W. L., Bakker, J., Vlaar, A. P. J., Abbasciano, R. G., Antonelli, M., Aubron, C., van Baarle, F. E. H. P., Cecconi, M., Dionne, J. C., Duranteau, J., Gyatt, G., Hunt, B. J., Juffermans, N. P., Lance, M., Meier, J., Muller, M. C. A. & 8 others, Murphy, G. J., Nielsen, N., Oczkowski, S. J., Perner, Anders, Raasveld, S. J., Schöchel, H., Wijnberge, M. & Cardiovascular Dynamics Section and Transfusion Task Force of the ESICM, C. D. S. A. T. T. F. O. T. E., 2022, In: Transfusion. 62, 2, p. 324-335 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Treatments of new-onset atrial fibrillation in critically ill patients: a systematic review with meta-analysis

    Wetterslev, M., Karlsen, Anders, Granholm, A., Haase, N., Hassager, Christian, Møller, Morten Hylander & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 432-446 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published

    Use of prokinetic agents in hospitalised adult patients: Protocol for a scoping review

    Crone, V., Møller, Morten Hylander, Perner, Anders, Alhazzani, W. & Krag, M., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 8, p. 1024-1026

    Research output: Contribution to journalReviewResearchpeer-review

  92. 2021
  93. Published

    Using machine learning for predicting intensive care unit resource use during the COVID-19 pandemic in Denmark

    Lorenzen, S. S., Nielsen, Mads, Jimenez-Solem, E., Petersen, Tonny Studsgaard, Perner, Anders, Thorsen-Meyer, H., Igel, Christian & Sillesen, Martin Hylleholt, 23 Sep 2021, In: Scientific Reports. 11, 1, 10 p., 18959.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Cardiac arrhythmias in critically ill patients with coronavirus disease 2019: A retrospective population-based cohort study

    Wetterslev, M., Jacobsen, P. K., Hassager, Christian, Jøns, C., Risum, N., Pehrson, S., Bastiansen, A., Andreasen, Anne Sofie, Tjelle Kristiansen, K., Bestle, Morten Heiberg, Mohr, T., Møller-Sørensen, H. & Perner, Anders, Jul 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 770-777 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Treating critically ill anemic patients with erythropoietin: less is more

    The ESICM Transfusion Guideline Part 1 Task force, T. E. T. G. P. 1. T. F., Feb 2021, In: Intensive Care Medicine. 47, 2, p. 256-257 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  96. Published

    A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock

    Torisson, G., Bruun Madsen, M., Schmidt Davidsen, A., Perner, Anders, Lipman, J., Dulhunty, J. & Sjövall, F., 2021, In: Critical Care Explorations. 3, 5, 10 p., e0383.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions

    Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R., Imberger, G., Jensen, B. T., Jonsson, A. B., Karam, O. & 25 others, Kong, D. Z., Korang, S. K., Koster, G., Lai, B., Liang, N., Lundstrøm, Lars Hyldborg, Marker, S., Meyhoff, T. S., Nielsen, E. E., Nørskov, A. K., Munch, M. W., Risom, E. C., Rygård, S. L., Safi, S., Sethi, N., Sjövall, F., Lauridsen, S. V., van Bakelen, N., Volbeda, M., van der Horst, I. C. C., Gluud, C., Perner, Anders, Møller, Morten Hylander, Keus, E. & Wetterslev, J., 2021, In: Journal of Clinical Epidemiology. 135, p. 29-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Acetate‐ vs lactate‐buffered crystalloid solutions: Protocol for a systematic review with meta‐analysis and trial sequential analysis

    Ellekjaer, K. L., Perner, Anders, Sivapalan, P. & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 123-127 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  99. Published

    COVID-19 versus influenza A/B supeRInfectionS in the IntenSive care unit (CRISIS): Protocol for a Danish nationwide cohort study

    Mikkelsen, V. S., Helleberg, M., Haase, N., Møller, Morten Hylander, Granholm, A., Storgaard, M., Jonsson, A. B., Schønning, Kristian, Reiter, N., Sigurðsson, S. Þ., Voldstedlund, M., Christensen, S. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1345-1350 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Characteristics, interventions, and longer term outcomes of COVID‐19 ICU patients in Denmark—A nationwide, observational study

    Haase, N., Plovsing, R., Christensen, S., Poulsen, L. M., Brøchner, A. C., Rasmussen, B. S., Helleberg, M., Jensen, J. U. S., Andersen, L. P. K., Siegel, H., Ibsen, M., Jørgensen, V., Winding, R., Iversen, S., Pedersen, H. P., Madsen, J., Sølling, C., Garcia, R. S., Michelsen, J., Mohr, T. & 10 others, Mannering, A., Espelund, U. S., Bundgaard, H., Kirkegaard, L., Smitt, M., Buck, D. L., Ribergaard, N., Pedersen, H. S., Christensen, B. V. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 68-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Clinical validation of precision medicine protocols: the last mile is the longest

    Casaer, M. P., De Jong, A. & Perner, Anders, 2021, In: Intensive Care Medicine. 47, p. 80-82 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  102. Published

    Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

    Jimenez-Solem, E., Petersen, T. S., Hansen, C., Hansen, C., Lioma, C., Igel, C., Boomsma, W., Krause, O., Lorenzen, S., Selvan, R., Petersen, J., Nyeland, M. E., Ankarfeldt, M. Z., Virenfeldt, G. M., Winther-Jensen, M., Linneberg, A., Ghazi, M. M., Detlefsen, N., Lauritzen, A. D., Smith, A. G. & 15 others, de Bruijne, Marleen, Ibragimov, Bulat, Petersen, Jens, Lillholm, Martin, Middleton, Jon Anthony, Mogensen, S. H., Thorsen-Meyer, H., Perner, Anders, Helleberg, M., Kaas-Hansen, Benjamin Skov, Bonde, M., Bonde, A., Pai, A., Nielsen, Mads & Sillesen, Martin Hylleholt, 2021, In: Scientific Reports. 11, 1, 12 p., 3246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia The COVID STEROID 2 Randomized Trial

    Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Saseedharan, S., Benfield, T., Wahlin, R. R., Rasmussen, B. S., Andreasen, A. S., Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brochner, A. C., Bestle, M. H., Helleberg, M., Michelsen, J., Padmanaban, A., Bose, N., Møller, A. & 59 others, Borawake, K., Kristiansen, K. T., Shukla, U., Chew, M. S., Dixit, S., Ulrik, Charlotte Suppli, Amin, P. R., Chawla, R., Wamberg, C. A., Shah, M. S., Darfelt, I. S., Jorgensen, V. L., Smitt, M., Granholm, A., Kjær, M. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, A., Cronhjort, M., Jakob, S. M., Gluud, C., Lange, Theis, Kadam, V., Marcussen, Klaus Vennick, Hollenberg, J., Hedman, A., Nielsen, H., Schjorring, O. L., Jensen, M. Q., Leistner, J. W., Jonassen, T. B., Kristensen, C. M., Clapp, E. C., Hjortso, C. J. S., Jensen, T. S., Halstad, L. S., Bak, E. R. B., Zaabalawi, R., Metcalf-Clausen, M., Abdi, S., Hatley, E. V., Aksnes, T. S., Gleipner-Andersen, E., Alarcon, A. F., Yamin, G., Heymowski, A., Berggren, A., La Cour, K., Weihe, S., Pind, A. H., Engstrom, J., Jha, V., Venkatesh, B. & Perner, Anders, 2021, In: J A M A: The Journal of the American Medical Association. 326, 18, p. 1807-1817 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Effect of immunoglobulin G on cytokine response in necrotising soft-tissue infection: A post hoc analysis

    Hedetoft, M., Madsen, M. B., Perner, Anders, Garred, Peter & Hyldegaard, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1293-1299 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 920990