Anders Bach

Anders Bach

Associate Professor


  1. 2022
  2. Published

    Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

    Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo

    Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, Burak, Strømgaard, K., Bach, Anders, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2021
  5. Published

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

    Leurs, U., Klein, Anders Bue, McSpadden, E. D., Griem-Krey, Nane, Solbak, Sara Marie Øie, Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, Stine Juul, Pedersen, Line Brogaard, Larsen, A. S. G., Shehata, Mohamed A., Kelstrup, C. D., Olsen, Jesper Velgaard, Bach, Anders, Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W., Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification of novel fragments binding to the PDZ1-2 domain of PSD-95

    Zang, Jie, Ye, F., Solbak, Sara Marie Øie, Høj, L. J., Zhang, M. & Bach, Anders, 2021, In: ChemMedChem. 16, 6, p. 949-954

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

    Grunddal, K. V., Diep, T. A., Petersen, N., Tough, I. R., Skov, Louise Julie, Liu, Lingzhi, Buijink, J. A., Mende, F., Jin, C., Jepsen, Sara Lind, Sørensen, L. M. E., Achiam, Michael Patrick, Strandby, R. B., Bach, Anders, Hartmann, Bolette, Frimurer, Thomas Michael, Hjorth, Siv Annegrethe, Bouvier, M., Cox, H. & Holst, Birgitte, 2021, In: Molecular Metabolism. 49, 14 p., 101207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery

    Quancard, J., Bach, Anders, Cox, B., Craft, R., Finsinger, D., Guéret, S. M., Hartung, I. V., Laufer, S., Messinger, J., Sbardella, G. & Koolman, H. F., 2021, In: ChemMedChem. 16, 11, p. 1737-1740

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2020
  11. Published

    The dynamics of linear polyubiquitin

    Jussupow, A., Messias, A. C., Stehle, R., Geerlof, A., Solbak, Sara Marie Øie, Paissoni, C., Bach, Anders, Sattler, M. & Camilloni, C., Oct 2020, In: Science Advances. 6, 42, 13 p., eabc3786.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, Gith, Jensen, Kathrine Louise, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, S., Bartling, Christian Reinhard Otto, Ammendrup-Johnsen, I., Pedersen, Sofie E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, Kaare, Arleth, Lise, Sørensen, Andreas Toft, Bach, Anders, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 1304261