Anders A. Jensen

Anders A. Jensen

Professor


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1 - 100 out of 182Page size: 100
  1. 2023
  2. Published

    Discovery of a Novel Class of Benzimidazole-Based Nicotinic Acetylcholine Receptor Modulators: Positive and Negative Modulation Arising from Overlapping Allosteric Sites

    Zhou, L., Dau, V. & Jensen, Anders A., 2023, In: Journal of Medicinal Chemistry. 66, 17, p. 12586–12601

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Evolutionary conservation of Zinc-Activated Channel (ZAC) functionality in mammals: a range of mammalian ZACs assemble into cell surface-expressed functional receptors

    Jensen, Anders A., 2023, In: Frontiers in Molecular Biosciences. 10, 11 p., 1265429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Identification of 5-HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library

    Yao, R., Jensen, Anders A., Bryce-Rogers, H. P., Schultz-Knudsen, Katrine, Zhou, L., Hovendal, N. P., Pedersen, H., Kubus, M., Ulven, Trond & Laraia, L., 2023, In: Journal of Medicinal Chemistry. 66, 16, p. 11536-11554

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist

    Marcher, Emil, Nykodemová, J., Harpsøe, Kasper, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2023, In: ACS Medicinal Chemistry Letters. 14, 3, p. 319–325

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Ligand selectivity hotspots in serotonin GPCRs

    Simon, Ícaro Ariel, Bjørn-Yoshimoto, Walden, Harpsøe, Kasper, Iliadis, S., Svensson, B., Jensen, Anders A. & Gloriam, David E., 2023, In: Trends in Pharmacological Sciences. 44, 12, p. 978-990

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats

    Kiilerich, K. F., Lorenz, J., Scharff, M. B., Speth, N., Brandt, T. G., Czurylo, J., Xiong, M., Jessen, N. S., Casado-Sainz, A., Shalgunov, Vladimir, Kjærby, Celia, Satała, G., Bojarski, A. J., Jensen, Anders A., Herth, Matthias Manfred, Cumming, P., Overgaard, A. & Palner, M., 2023, In: Molecular Psychiatry. 28, 9, p. 3829-3841

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists

    Pottie, E., Poulie, Christian Bernard Matthijs, Simon, Ícaro Ariel, Harpsøe, Kasper, D’Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Kristensen, Jesper Langgaard & Stove, C. P., 2023, In: ACS Chemical Neuroscience. 14, 15, p. 2727–2742

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

    Alexander, S. P. H., Mathie, A. A., Peters, J. A., Veale, E. L., Striessnig, J., Kelly, E., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Aldrich, R. W., Attali, B., Baggetta, A. M., Becirovic, E., Biel, M., Bill, R. M., Caceres, A. I., Catterall, W. A., Conner, A. C., Davies, P. & 53 others, De Clerq, K., Delling, M., Di Virgilio, F., Falzoni, S., Fenske, S., Fortuny-Gomez, A., Fountain, S., George, C., Goldstein, S. A. N., Grimm, C., Grissmer, S., Ha, K., Hammelmann, V., Hanukoglu, I., Hu, M., Ijzerman, A. P., Jabba, S. V., Jarvis, M., Jensen, Anders A., Jordt, S. E., Kaczmarek, L. K., Kellenberger, S., Kennedy, C., King, B., Kitchen, P., Liu, Q., Lynch, J. W., Meades, J., Mehlfeld, V., Nicke, A., Offermanns, S., Perez-Reyes, E., Plant, L. D., Rash, L., Ren, D., Salman, M. M., Sieghart, W., Sivilotti, L. G., Smart, T. G., Snutch, T. P., Tian, J., Trimmer, J. S., Van den Eynde, C., Vriens, J., Wei, A. D., Winn, B. T., Wulff, H., Xu, H., Yang, F., Fang, W., Yue, L., Zhang, X. & Zhu, M., 2023, In: British Journal of Pharmacology. 180 , Suppl 2, p. S145-S222

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2022
  12. Published

    Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

    Chałupnik, P., Vialko, A., Pickering, Darryl S, Hinkkanen, M., Donbosco, S., Møller, T. C., Jensen, Anders A., Nielsen, Birgitte, Bay, Yasmin, Kristensen, Anders Skov, Johansen, Tommy Nørskov, Łątka, K., Bajda, M. & Szymańska, E., 2022, In: International Journal of Molecular Sciences. 23, 15, 16 p., 8797.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists

    Poulie, Christian Bernard Matthijs, Pottie, E., Simon, I. A., Harpsøe, Kasper, D’andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Stove, C. P. & Kristensen, Jesper Langgaard, 2022, In: Journal of Medicinal Chemistry. 65, 18, p. 12031–12043

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective

    Zlotos, D. P., Mandour, Y. M. & Jensen, Anders A., 2022, In: Natural Product Reports. 39, 10, p. 1910-1937

    Research output: Contribution to journal › Review › Research › peer-review

  15. 2021
  16. Published

    25CN-NBOH: A selective agonist for in vitro and in vivo investigations of the serotonin 2A receptor

    Marcher, Emil, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2021, In: ChemMedChem. 16, 21, p. 3263-3270

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors

    Zlotos, D. P., Abdelmalek, C. M., Botros, L. S., Banoub, M. M., Mandour, Y. M., Breitinger, U., El Nady, A., Breitinger, H., Sotriffer, C., Villmann, C., Jensen, Anders A. & Holzgrabe, U., 2021, In: Journal of Natural Products. 84, 2, p. 382-394

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes

    Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Discovery and functional characterization of N-(thiazol-2-yl)-benzamide analogs as the first class of selective antagonists of the Zinc-Activated Channel (ZAC)

    Madjroh, Nawid, Mellou, E., Davies, P. A., Söderhielm, P. C. & Jensen, Anders A., 2021, In: Biochemical Pharmacology. 193, 16 p., 114782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Erythrina Alkaloid Analogues as nAChR Antagonists-A Flexible Platform for Leads in Drug Discovery

    Clementson, S., Matheu, S. A., Marcher, Emil, Pedersen, H., Jensen, Anders A., Clausen, Rasmus Prætorius, Vital, P., Glibstrup, E., Jessing, M. & Kristensen, Jesper Langgaard, 2021, In: The Journal of Organic Chemistry. 86, 12, p. 8248-8262

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Probing the molecular basis for signal transduction through the Zinc-Activated Channel (ZAC)

    Madjroh, Nawid, Mellou, E., Æbelø, L., Davies, P. A., Söderhielm, P. C. & Jensen, Anders A., 2021, In: Biochemical Pharmacology. 193, 18 p., 114781.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The concise guide to pharmacology 2021/22: Ion channels

    Alexander, S. P., Mathie, A., Peters, J. A., Veale, E. L., Striessnig, J., Kelly, E., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Southan, C., Davies, J. A., Aldrich, R. W., Attali, B., Baggetta, A. M., Becirovic, E., Biel, M., Bill, R. M., Catterall, W. A., Conner, A. C. & 38 others, Davies, P., Delling, M., Virgilio, F. D., Falzoni, S., Fenske, S., George, C., Goldstein, S. A. N., Grissmer, S., Ha, K., Hammelmann, V., Hanukoglu, I., Jarvis, M., Jensen, Anders A., Kaczmarek, L. K., Kellenberger, S., Kennedy, C., King, B., Kitchen, P., Lynch, J. W., Perez-Reyes, E., Plant, L. D., Rash, L., Ren, D., Salman, M. M., Sivilotti, L. G., Smart, T. G., Snutch, T. P., Tian, J., Trimmer, J. S., Van den Eynde, C., Vriens, J., Wei, A. D., Winn, B. T., Wulff, H., Xu, H., Yue, L., Zhang, X. & Zhu, M., 2021, In: British Journal of Pharmacology. 178 , Suppl. 1, p. S157-S245

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2020
  24. Published

    Pharmacological Characterization of the Zinc-Activated Channel: A Cys-Loop Receptor Gated by Zn2+, Cu2+ and Protons

    Madjroh, Nawid, Jensen, Anders A. & Davies, P. A., 7 Feb 2020, p. 582A-582A.

    Research output: Contribution to conference › Conference abstract for conference › Research

  25. Published

    Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors

    Sandager-Nielsen, K., Ahring, P. K., Klein, J., van Hout, M., Thaneshwaran, S., Brito dos Santos, Altair, Jacobsen, T. A., Amrutkar, D. V., Peters, D., Jensen, Anders A., Kohlmeier, Kristi Anne, Christophersen, P. & Dyhring, T., 2020, In: Biochemical Pharmacology. 174, 13 p., 113786.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Characterization of AN6001, the first positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors

    van Hout, M., Klein, J., Ahring, P. K., Brown, D. T., Thaneshwaran, S., Brito dos Santos, Altair, Jensen, Anders A., Kohlmeier, Kristi Anne, Christophersen, P. & Dyhring, T., 2020, In: Biochemical Pharmacology. 174, 113788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Comparison of biophysical properties of α1β2 and α3β2 GABAA receptors in whole-cell patch-clamp electrophysiological recordings

    Olander, E. R., Janzen , D., Villmann , C. & Jensen, Anders A., 2020, In: P L o S One. 15, 6, 13 p., e0234080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Dark Classics in Chemical Neuroscience: NBOMes

    Poulie, Christian Bernard Matthijs, Jensen, Anders A., Halberstadt, A. & Kristensen, Jesper Langgaard, 2020, In: ACS Chemical Neuroscience. p. 3860–3869 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Design, Synthesis, and Pharmacological Characterization of Heterobivalent Ligands for the Putative 5-HT2A/mGlu2 Receptor Complex

    Poulie, Christian Bernard Matthijs, Liu, N., Jensen, Anders A. & Bunch, Lennart, 2020, In: Journal of Medicinal Chemistry. 63, 17, p. 9928-9949 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    From Methaqualone and Beyond: Structure-Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA Receptors

    Wang, P., Jensen, Anders A. & Bunch, Lennart, 2020, In: ACS Chemical Neuroscience. 11, 24, p. 4362-4375

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay

    Gadgaard, C. & Jensen, Anders A., 2020, In: Biochemical Pharmacology. 175, 13 p., 113870.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Investigation of the 2,5-dimethoxy motif in phenethylamine Serotonin 2A receptor agonists

    Marcher, Emil, Halberstadt, A. L., Klein, A. K., Chatha, M., Jademyr, S., Jensen, Anders A. & Kristensen, Jesper Langgaard, 2020, In: ACS Chemical Neuroscience. 11, p. 1238-1244

    Research output: Contribution to journal › Letter › Research › peer-review

  33. Published

    The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

    Jensen, Anders A., Halberstadt, A. L., Marcher, Emil, Odland, Anna Ulstein, Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner, Hans, Palner, M., Andreasen T., Jesper & Kristensen, Jesper Langgaard, 2020, In: Biochemical Pharmacology. 177, 16 p., 113979.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs)

    Liu, N., Jensen, Anders A. & Bunch, Lennart, 2020, In: ACS Medicinal Chemistry Letters. 11, 11, p. 2212-2220 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2019
  36. Published

    THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

    CGTP Collaborators, C. C., Dec 2019, In: British Journal of Pharmacology. 176, Suppl 1, p. S142-S228

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors

    Zlotos, D. P., Mohsen, A. M. Y., Mandour, Y. M., Marzouk, M. A., Breitinger, U., Villmann, C., Breitinger, H., Sotriffer, C., Jensen, Anders A. & Holzgrabe, U., 6 Aug 2019, In: Journal of Natural Products. 82, p. 2332-2336

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at gamma-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters

    Giraudo, A., Krall, J., Bavo, Francesco, Nielsen, Birgitte, Kongstad, Kenneth Thermann, Rolando, B., De Blasio, R., Gloriam, David E., Löffler, R., Thiesen, L., Harpsøe, Kasper, Frydenvang, Karla Andrea, Boschi, D., Wellendorph, Petrine, Lolli, M. L., Jensen, Anders A. & Frølund, Bente, 27 Jun 2019, In: Journal of Medicinal Chemistry. 62, 12, p. 5797-5809

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters

    Poulie, Christian Bernard Matthijs, Alcaide Lopez, A., Krell-Jørgensen, M. P., Larsen, Y., Astier, E., Bjørn-Yoshimoto, Walden, Yi, F., Syrenne, J. T., Storgaard, M., Nielsen, Birgitte, Frydenvang, Karla Andrea, Jensen, Anders A., Hansen, K. B., Pickering, Darryl S & Bunch, Lennart, 19 Jun 2019, In: A C S Chemical Neuroscience. 10, 6, p. 2989-3007 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites

    Krall, J., Bavo, Francesco, Falk-Petersen, C. B., Jensen, C. H., Nielsen, J. O., Tian, Yongsong, Anglani, V., Kongstad, Kenneth Thermann, Petersen, Louise Piilgaard, Nielsen, Birgitte, Gloriam, David E., Kehler, J., Jensen, Anders A., Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 14 Mar 2019, In: Journal of Medicinal Chemistry. 62, 5, p. 2798-2813

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Developing New 4-PIOL and 4-PHP Analogues for Photoinactivation of γ-Aminobutyric Acid Type A Receptors

    Mortensen, M., Krall, J., Kongstad, Kenneth Thermann, Brygger, B. M., Lenzi, O., Francotte, P., Sørensen, T. E., Nielsen, Birgitte, Jensen, Anders A., Smart, T. G. & Frølund, Bente, 2019, In: ACS Chemical Neuroscience. 10, 11, p. 4669-4684

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Identification and Structure-Activity Relationship Study of Imidazo[1,2-a]pyridine-3-amines as First Selective Inhibitors of Excitatory Amino Acid Transporter Subtype 3 (EAAT3)

    Wu, P., Bjørn-Yoshimoto, Walden, Staudt, Markus, Jensen, Anders A. & Bunch, Lennart, 2019, In: ACS Chemical Neuroscience. 10, p. 4414-4429

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Modulation of thalamo-cortical activity by the NMDA receptor antagonists ketamine and phencyclidine in the awake freely-moving rat

    Amat-Foraster, M., Celada, P., Richter, U., Jensen, Anders A., Plath, N., Artigas, F. & Herrik, K. F., 2019, In: Neuropharmacology. 158, 14 p., 107745.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool for the Development of Ionotropic Glutamate Receptor Ligands

    Sainas, S., Temperini, P., Farnsworth, J. C., Yi, F., Møllerud, S., Jensen, Anders A., Nielsen, Birgitte, Kastrup, Jette Sandholm Jensen, Hansen, K. B., Boschi, D., Pickering, Darryl S, Clausen, Rasmus Prætorius & Lolli, M., 2019, In: Journal of Medicinal Chemistry. 62, p. 4467-4482

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors

    van Hout, M., Valdes, A., Christensen, S. B., Tran, P. T., Watkins, M., Gajewiak, J., Jensen, Anders A., Olivera, B. M. & McIntosh, J. M., 2019, In: Neuropharmacology. 157, 107691.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2018
  47. Published

    Conformational transitions of the serotonin 5-HT3 receptor

    Polovinkin, L., Hassaine, G., Perot, J., Neumann, E., Jensen, Anders A., Lefebvre, S. N., Corringer, P., Neyton, J., Chipot, C., Dehez, F., Schoehn, G. & Nury, H., Nov 2018, In: Nature. 563, 7730, p. 275-279 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Chemoenzymatic synthesis and pharmacological characterization of functionalized aspartate analogues as novel excitatory amino acid transporter inhibitors

    Fu, H., Zhang, J., Tepper, P. G., Bunch, Lennart, Jensen, Anders A. & Poelarends, G. J., 13 Sep 2018, In: Journal of Medicinal Chemistry. 61, 17, p. 7741-7753

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Probing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABAA receptors

    Söderhielm, P. C., Balle, T., Bak-Nyhus, S., Zhang, M., Hansen, K. M., Ahring, P. K. & Jensen, Anders A., Aug 2018, In: Biochemical Pharmacology. 158, p. 339-358

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

    Peng, Y., McCorvy, J. D., Harpsøe, K., Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajsen, L. F., Huang, X., Wu, Y., Shen, L., Bjørn-Yoshimoto, W. E., Ding, K., Wacker, D., Han, G. W., Cheng, J., Katritch, V., Jensen, A. A. & 6 others, Hanson, M. A., Zhao, S., Gloriam, David E., Roth, B. L., Stevens, R. C. & Liu, Z., 2018, In: Cell. 172, 4, p. 719-730 P719-730.E14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors

    Olander, E. R., Madjroh, Nawid, Bunch, Lennart, Söderhielm, P. C. & Jensen, Anders A., 2018, In: Biochemical Pharmacology. 150, p. 305-319

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts

    Crestey, F., Jensen, Anders A., Soerensen, C., Magnus, C. B., Andreasen T., Jesper, Peters, G. H. J. & Kristensen, Jesper Langgaard, 2018, In: Journal of Medicinal Chemistry. 61, p. 1719-1729

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Functional Properties and Mechanism of Action of PPTQ, an Allosteric Agonist and Low Nanomolar Positive Allosteric Modulator at GABAA Receptors

    Madjroh, Nawid, Olander, E. R., Bundgaard, C., Söderhielm, P. C. & Jensen, Anders A., 2018, In: Biochemical Pharmacology. 147, p. 153-169

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Functional characterization of alpha7 nicotinic acetylcholine and NMDA receptor signaling in SH-SY5Y neuroblastoma cells in an ERK phosphorylation assay

    Elnagar, M. R., Walls, Anne Byriel, Helal, G. K., Hamada, F. M., Thomsen, M. S. & Jensen, Anders A., 2018, In: European Journal of Pharmacology. 826, p. 106-113

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Profiling of GABAA and GABAB receptor expression in the myometrium of the human uterus

    Söderhielm, P. C., Klein, A. B., Bomholtz, Sofia Hammami & Jensen, Anders A., 2018, In: Life Sciences. 214, p. 145-152

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Temporally dissociable effects of ketamine on neuronal discharge and gamma oscillations in rat thalamo-cortical networks

    Amat-Foraster, M., Jensen, Anders A., Plath, N., Herrik, K. F., Celada, P. & Artigas, F., 2018, In: Neuropharmacology. 137, p. 13-23

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2017
  58. Published

    18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, Anders A., Gillings, N., Lehel, S., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, Apr 2017, In: Organic & Biomolecular Chemistry. 15, p. 4351-4358

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE

    Jepsen, T. H., Glibstrup, E., Crestey, F. L. J., Jensen, Anders A. & Kristensen, Jesper Langgaard, 2017, In: Beilstein Journal of Organic Chemistry. 13, p. 988-994 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist

    Jensen, Anders A., McCorvy, J. D., Petersen, S. L., Bundgaard, C., Liebscher, G., Kenakin, T. P., Bräuner, Hans, Kehler, J. & Kristensen, Jesper Langgaard, 2017, In: Journal of Pharmacology and Experimental Therapeutics. 361, 3, p. 441-453

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Functional characterization of GABAA receptor-mediated modulation of cortical neuron network activity in microelectrode array recordings

    Bader, B. M., Steder, A., Klein, A. B., Frølund, Bente, Schroeder, O. H. U. & Jensen, Anders A., 2017, In: PloS One. 12, 10, 32 p., e0186147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue

    Elnagar, M. R., Walls, Anne Byriel, Helal, G. K., Hamada, F. M., Thomsen, M. S. & Jensen, Anders A., 2017, In: PLOS ONE. 12, 21 p., e0189513.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. 2016
  64. Published

    Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists

    Mohsen, A. M. Y., Mandour, Y. M., Sarukhanyan, E., Breitinger, U., Villmann, C., Banoub, M. M., Breitinger, H., Dandekar, T., Holzgrabe, U., Sotriffer, C., Jensen, Anders A. & Zlotos, D. P., 14 Dec 2016, In: Journal of Natural Products. 79, 12, p. 2997–3005 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of ionotropic glutamate receptor binding pocket

    Tamborini, L., Nicosia, V., Conti, P., Dall'Oglio, F., De Micheli, C., Nielsen, Birgitte, Jensen, Anders A., Pickering, Darryl S & Pinto, A., 1 Dec 2016, In: Tetrahedron. 72, 51, p. 8586-8492 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ1 γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone

    Krall, J., Brygger, B. M., Sigurðardóttir, S. B., Ng, C. K. L., Bundgaard, C., Kehler, J., Nielsen, Birgitte, Bek, T., Jensen, Anders A. & Frølund, Bente, 13 Sep 2016, In: ChemMedChem. 11, 20, p. 2299-2310 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    5-HT2A/5-HT2C receptor pharmacology and intrinsic clearance of N-benzylphenethylamines modified at the primary site of metabolism

    Leth-Petersen, S., Petersen, I. N., Jensen, Anders A., Bundgaard, C., Bæk, M., Kehler, J. & Kristensen, Jesper Langgaard, 26 Aug 2016, In: A C S Chemical Neuroscience. p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    A parallel panning scheme used for selection of a GluA4-specific Fab targeting the ligand-binding domain

    Clausen, Rasmus Prætorius, Mohr, A. Ø., Riise, E., Jensen, Anders A., Gill, A., Madden, D. R., Kastrup, Jette Sandholm Jensen & Skottrup, P. D., 8 Jul 2016, In: International Journal of Biological Macromolecules. 92, p. 779-787 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism

    Chua, H. C., Christensen, E. H. T., Hoestgaard-Jensen, K., Hartiadi, L. Y., Ramzan, I., Jensen, Anders A., Absalom, N. L. & Chebib, M., 23 Jun 2016, In: P L o S One. 11, 6, p. 1-17 17 p., e0157700.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Synthesis and evaluation of 18F-labeled 5-HT2A receptor agonists as PET ligands

    Herth, Matthias Manfred, Petersen, I. N., Hansen, H. D., Hansen, M., Ettrup, A., Jensen, Anders A., Lehel, S., Dyssegaard, A., Gillings, N., Knudsen, G. M. & Kristensen, Jesper Langgaard, 19 Apr 2016, In: Nuclear Medicine and Biology. 43, 8, p. 455-462 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Beta-Sulfonamido Functionalized Aspartate Analogs as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype-Selectivity Profiles Arising from Subtle Structural Differences

    Hansen, J. C., Bjørn-Yoshimoto, Walden, Bisballe, N., Nielsen, Birgitte, Jensen, Anders A. & Bunch, Lennart, 2016, In: Journal of Medicinal Chemistry. 59, p. 8771-8786 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Acetylcholine

    Jensen, Anders A., 2016, Textbook of drug design and discovery. Strømgaard, K., Krogsgaard-Larsen, P. & Madsen, U. (eds.). 5 ed. Taylor & Francis

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  73. Published

    Bioavailability studies and in vitro profiling of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-102)

    Haym, I., Huynh, Tri Hien Viet, Hansen, S. W., Pedersen, M. H. F., Ruiz, J. A., Erichsen, M. N., Gynther, M., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Eriksen, A. L., Jensen, Anders A. & Bunch, Lennart, 2016, In: ChemMedChem. 11, 4, p. 403-419 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, Anders A., Lehel, S., Gillings, N., Herth, Matthias Manfred, Knudsen, G. M. & Kristensen, Jesper Langgaard, 2016, In: Bioorganic & Medicinal Chemistry. 24, p. 5353-5356 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Copper and protons directly activate the zinc-activated channel

    Trattnig, S. M., Gasiorek, A., Deeb, T. Z., Comenencia Ortiz, E. J., Moss, S. J., Jensen, Anders A. & Davies, P. A., 2016, In: Biochemical Pharmacology. 103, p. 109-117 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 Receptors

    Gasiorek, A., Trattnig, S. M., Ahring, P. K., Kristiansen, Uffe, Frølund, Bente, Frederiksen, K. & Jensen, Anders A., 2016, In: Biochemical Pharmacology. 110-111, p. 92-108 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Identification of a New Class of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors Followed by a Structure-Activity-Relationship Study

    Hansen, S. W., Erichsen, M. N., Fu, B., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Hansen, J. C., Jensen, Anders A. & Bunch, Lennart, 2016, In: Journal of Medicinal Chemistry. 59, 19, p. 8757-8770 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    New insights into the structure-activity-relationship of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitors UCPH-101 and UCPH-102

    Hansen, S. W., Erichsen, M. N., Huynh, Tri Hien Viet, Ruiz, J. A., Haym, I., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Hansen, Jeanette Venla, Storgaard, M., Eriksen, A. L., Jensen, Anders A. & Bunch, Lennart, 2016, In: ChemMedChem. 11, 4, p. 382-402 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

    Wang, S., Larsen, Y., Navarrete, C. V., Jensen, Anders A., Nielsen, Birgitte, Al-Musaed, A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Pickering, Darryl S & Clausen, Rasmus Prætorius, 2016, In: Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. 2015
  81. Published

    Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors

    Petersen, I. N., Crestey, F., Jensen, Anders A., Indurthi, D. C., Pedersen, H., Andreasen T., Jesper, Balle, T. & Kristensen, Jesper Langgaard, 9 Apr 2015, In: A C S Medicinal Chemistry Letters. 6, 4, p. 472-475 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    A multifaceted GABAA receptor modulator: Functional properties and mechanism of action of the sedative-hypnotic and recreational drug methaqualone (Quaalude)

    Hammer, H., Bader, B. M., Ehnert, C., Bundgaard, C., Bunch, Lennart, Hoestgaard-Jensen, K., Schroeder, O. H., Bastlund, J. F., Gramowski-Voß, A. & Jensen, Anders A., 2015, In: Molecular Pharmacology. 88, 2, p. 401-420 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations

    de la Fuente Revenga, M., Balle, T., Jensen, Anders A. & Frølund, Bente, 2015, In: European Journal of Medicinal Chemistry. 102, p. 352-362 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities

    Jensen, Anders A., Fahlke, C., Bjørn-Yoshimoto, Walden & Bunch, Lennart, 2015, In: Current Opinion in Pharmacology. 20, p. 116-123 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane.

    Bach, T. B., Jensen, Anders A., Petersen, J. G., Sørensen, T. E., Volpe, S. D., Liu, J., Blaazer, A. R., van Muijlwijk-Koezen, J. E., Balle, T. & Frølund, Bente, 2015, In: European Journal of Medicinal Chemistry. 102, p. 425-444 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Functional characterization of the 1,5-benzodiazepine clobazam and its major active metabolite N-desmethylclobazam at human GABAA receptors expressed in Xenopus laevis oocytes

    Hammer, H., Ebert, B., Jensen, H. S. & Jensen, Anders A., 2015, In: P L o S One. 10, p. 1-21 21 p., e0120239.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Identification of the first highly selective inhibitor of human GABA transporter GAT3

    Damgaard, M., Al-Khawaja, A., Vogensen, S. B., Jurik, A., Sijm, M., Lie, M., Bæk, M. I., Rosenthal, E., Jensen, Anders A., Ecker, G. F., Frølund, Bente, Wellendorph, Petrine & Clausen, Rasmus Prætorius, 2015, In: A C S Chemical Neuroscience. 6, p. 1591-1599 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Targeting α4β2 nAChRs in CNS disorders: Perspectives on positive allosteric modulation as a therapeutic approach

    Grupe, M., Grunnet, M., Bastlund, J. F. & Jensen, Anders A., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 3, p. 187-200 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The metabolic impact of β-hydroxybutyrate on neurotransmission: Reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity

    Lund, Trine Meldgaard, Ploug, K. B., Iversen, A., Jensen, Anders A. & Jansen-Olesen, I., 2015, In: Journal of Neurochemistry. 132, 5, p. 520-531 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. 2014
  92. Published

    5-(Piperidin-4-yl)-3-Hydroxypyrazole: A Novel Scaffold for Probing the Orthosteric γ-Aminobutyric Acid Type A Receptor Binding Site

    Krall, J., Kongstad, Kenneth Thermann, Nielsen, Birgitte, Sørensen, T. E., Balle, T., Jensen, Anders A. & Frølund, Bente, 2014, In: ChemMedChem. 9, 11, p. 2475-2485 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    GABAB receptor phosphorylation regulates KCTD12-induced K+ current desensitization

    Adelfinger, L., Turecek, R., Ivankova, K., Jensen, Anders A., Moss, S. J., Gassmann, M. & Bettler, B., 2014, In: Biochemical Pharmacology. 91, 3, p. 369-379 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Novel aza-analogous ergoline derived scaffolds as potent serotonin 5-HT6 and dopamine D2 receptor ligands

    Krogsgaard-Larsen, N., Jensen, Anders A., Schrøder, T. J., Christoffersen, C. T. & Kehler, J., 2014, In: Journal of Medicinal Chemistry. 57, 13, p. 5823-5828 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Pharmacological characterisation of α6β4* nicotinic acetylcholine receptors assembled from three different α6/α3 subunit chimeras in tsA201 cells

    Jensen, A. B., Hoestgaard-Jensen, K. & Jensen, Anders A., 2014, In: European Journal of Pharmacology. 740, p. 703-713 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Probing for improved potency and in vivo bioavailability of excitatory amino acid transporter subtype 1 inhibitors UCPH-101 and UCPH-102: Design, synthesis and pharmacological evaluation of substituted 7-biphenyl analogs

    Erichsen, M. N., Hansen, J., Artacho Ruiz, J., Demmer, C. S., Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Jensen, Anders A. & Bunch, Lennart, 2014, In: Neurochemical Research. 39, 10, p. 1964-1979 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Probing α4βδ GABAA Receptor Heterogeneity: Differential Regional Effects of a Functionally Selective α4β1δ/α4β3δ Receptor Agonist on Tonic and Phasic Inhibition in Rat Brain

    Hoestgaard-Jensen, K., Dalby, N. O., Krall, J., Hammer, H., Krogsgaard-Larsen, Povl, Frølund, Bente & Jensen, Anders A., 2014, In: Journal of Neuroscience. 34, 49, p. 16256-16272 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle-type nAChRs, and the allosteric binding site of muscarinic M2 receptors

    Zlotos, D. P., Tränkle, C., Holzgrabe, U., Gündisch, D. & Jensen, Anders A., 2014, In: Journal of Natural Products. 77, 9, p. 2006-2013 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Structure-activity relationships of strychnine analogues at glycine receptors

    Mohsen, A. M. Y., Heller, E., Holzgrabe, U., Jensen, Anders A. & Zlotos, D. P., 2014, In: Chemistry & Biodiversity. 11, 8, p. 1256-1262 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Synthesis and pharmacological evaluation of 6-aminonicotinic acid analogues as novel γ-aminobutyric acidA receptor agonists

    Petersen, J. G., Sørensen, T. E., Damgaard, M., Nielsen, Birgitte, Jensen, Anders A., Balle, T., Bergmann, R. & Frølund, Bente, 2014, In: European Journal of Medicinal Chemistry. 84, p. 404-416 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Synthesis and pharmacological evaluation of DHβE analogs as neuronal nicotinic acetylcholine receptor antagonists

    Jepsen, T. H., Jensen, Anders A., Lund, M. H., Glibstrup, E. & Kristensen, Jesper Langgaard, 2014, In: A C S Medicinal Chemistry Letters. 5, 7, p. 766-770 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Synthesis of (3-hydroxy-pyrazolin-5-yl)glycine based ligands interacting with ionotropic glutamate receptors

    Pinto, A., Tamborini, L., Mastronardi, F., Ettari, R., Safoz, Y., Bunch, Lennart, Nielsen, Birgitte, Jensen, Anders A., De Micheli, C. & Conti, P., 2014, In: European Journal of Medicinal Chemistry. 75, p. 151-158 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. 2013
  104. Published

    The orthosteric GABAA receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors

    Hoestgaard-Jensen, K., O'Connor, R. M., Dalby, N. O., Simonsen, C., Finger, B. C., Golubeva, A., Hammer, H., Bergmann, M. L., Kristiansen, Uffe, Krogsgaard-Larsen, Povl, Bräuner, Hans, Ebert, B., Frølund, Bente, Cryan, J. F. & Jensen, Anders A., Oct 2013, In: British Journal of Pharmacology. 170, 4, p. 919-32 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Exploring the orthosteric binding site of the γ-aminobutyric acid type A receptor using 4-(piperidin-4-yl)-1-hydroxypyrazoles 3- or 5-imidazolyl substituted: design, synthesis, and pharmacological evaluation

    Krall, J., Jensen, C. H., Sørensen, T. E., Nielsen, Birgitte, Jensen, Anders A., Sander, T., Balle, T. & Frølund, Bente, 15 Jul 2013, In: Journal of Medicinal Chemistry. 56, 16, p. 6536−6540 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Design, synthesis, and pharmacological characterization of N- and O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: novel 5-HT(2A)/5-HT(2C) receptor agonists with pro-cognitive properties

    Jensen, Anders A., Plath, N., Pedersen, M. H. F., Isberg, V., Krall, J., Wellendorph, Petrine, Stensbøl, T. B., Gloriam, David E., Krogsgaard-Larsen, Povl & Frølund, Bente, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1211-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. Published

    Allosteric modulation of an excitatory amino acid transporter: The subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain

    Abrahamsen, B., Schneider, N., Erichsen, M. N., Huynh, Tri Hien Viet, Fahlke, C., Bunch, Lennart & Jensen, Anders A., 2013, In: Journal of Neuroscience. 33, 3, p. 1068-1087

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters

    Assaf, Z., Larsen, A. P., Venskutonyte, R., Han, L., Abrahamsen, B., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Jensen, Anders A., Pickering, Darryl S, Frydenvang, Karla Andrea, Gefflaut, T. & Bunch, Lennart, 2013, In: Journal of Medicinal Chemistry. 56, 4, p. 1614-1628

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Design, synthesis and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists

    Crestey, F., Jensen, Anders A., Borch, M., Andreasen T., Jesper, Andersen, J., Balle, T. & Kristensen, Jesper Langgaard, 2013, In: Journal of Medicinal Chemistry. 56, 23, p. 9673-9682

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Discovery of a subtype-selective of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

    Kragholm, B., Kvist, T., Madsen, K. K., Jørgensen, L., Vogensen, S. B., Schousboe, Arne, Clausen, Rasmus Prætorius, Jensen, Anders A. & Bräuner, Hans, 2013, In: Biochemical Pharmacology. 86, p. 521-528

    Research output: Contribution to journal › Journal article › Research › peer-review

  111. Published

    Elucidation of molecular impediments in the α6 subunit for in vitro expression of functional α6β4* nicotinic acetylcholine receptors

    Jensen, A. B., Hoestgaard-Jensen, K. & Jensen, Anders A., 2013, In: Journal of Biological Chemistry. 288, 47, p. 33708-33721

    Research output: Contribution to journal › Journal article › Research › peer-review

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