Alexander Lund Nielsen

Alexander Lund Nielsen

PhD Student


Publication year:
  1. 2021
  2. E-pub ahead of print

    Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

    Troelsen, Kathrin Sten, Bæk, Michael, Nielsen, Alexander Lund, Madsen, A. S., Rajabi, N. & Olsen, Christian Adam, Feb 2021, In : RSC Chemical Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

    Nielsen, Alexander Lund, Rajabi, N., Kudo, N., Larsen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, Michael, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 14 Jan 2021, In : RSC Chemical Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Covalent inhibition of botulinum neurotoxin A – Exploration of warhead reactivity and function using a bifunctional approach

    Turner, L. D., Nielsen, Alexander Lund, Lin, L., Pellett, S., Sugane, T., Olson, M. E. & Janda, K. D., 2021, p. S72-S73. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  5. 2020
  6. Published

    Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A

    Lin, L., Olson, M. E., Sugane, T., Turner, L. D., Tararina, M. A., Nielsen, Alexander Lund, Kurbanov, E. K., Pellett, S., Johnson, E. A., Cohen, S. M., Allen, K. N. & Janda, K. D., 18 Sep 2020, In : Journal of Medicinal Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Finding the gas pedal on a slow sirtuin

    Nielsen, Alexander Lund & Olsen, Christian Adam, 31 Jan 2020, In : Journal of Biological Chemistry. 295, p. 400-401

    Research output: Contribution to journalLiterature reviewResearchpeer-review

  8. Published

    Dethioacylation by sirtuins 1–3: Considerations for drug design using mechanism-based sirtuin inhibition

    Rajabi, N., Nielsen, Alexander Lund & Olsen, Christian Adam, 2020, In : A C S Medicinal Chemistry Letters. 11, 10, p. 1886-1892

    Research output: Contribution to journalLetterResearchpeer-review

  9. Published

    Neurotrophic effects of vascular endothelial growth factor B and novel mimetic peptides on neurons from the central nervous system

    Dmytriyeva, O., de Diego Ajenjo, Amaia, Larsen, Kathrine Lundø, Hertz, Henrik, Rasmussen, K. K., Christiansen, A. T., Klingelhofer, J., Nielsen, Alexander Lund, Hoeber, J., Kozlova, E. N., Woldbye, David Paul Drucker & Pankratova, Stanislava, 2020, In : ACS Chemical Neuroscience. 11, 9, p. 1270–1282 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Recent achievements in developing selective Gq inhibitors

    Zhang, H., Nielsen, Alexander Lund & Strømgaard, Kristian, 2020, In : Medicinal Research Reviews. 40, 1, p. 135-157

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells

    Nielsen, Alexander Lund, Rajabi, N., Kudo, N., Larsen, Kathrine Lundø, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2020, In : bioRxiv. 26 p.

    Research output: Contribution to journalJournal articleResearch

  12. 2018
  13. Published

    Potent and selective inhibition of sirtuin 2 deacylation

    Nielsen, Alexander Lund, Rajabi, N., Madsen, A. & Olsen, Christian Adam, 19 Aug 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

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