Urinary phthalate concentrations in mothers and their children in Ireland: Results of the DEMOCOPHES human biomonitoring study

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Urinary phthalate concentrations in mothers and their children in Ireland : Results of the DEMOCOPHES human biomonitoring study. / Cullen, Elizabeth; Evans, David; Griffin, Chris; Burke, Padraig; Mannion, Rory; Burns, Damien; Flanagan, Andrew; Kellegher, Ann; Schoeters, Greet; Govarts, Eva; Biot, Pierre; Casteleyn, Ludwine; Castaño, Argelia; Kolossa-Gehring, Marike; Esteban, Marta; Schwedler, Gerda; Koch, Holger M.; Angerer, Jürgen; Knudsen, Lisbeth E.; Joas, Reinhard; Joas, Anke; Dumez, Birgit; Sepai, Ovnair; Exley, Karen; Aerts, Dominique.

In: International Journal of Environmental Research and Public Health, Vol. 14, No. 12, 1456, 12.2017, p. 1-12.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Cullen, E, Evans, D, Griffin, C, Burke, P, Mannion, R, Burns, D, Flanagan, A, Kellegher, A, Schoeters, G, Govarts, E, Biot, P, Casteleyn, L, Castaño, A, Kolossa-Gehring, M, Esteban, M, Schwedler, G, Koch, HM, Angerer, J, Knudsen, LE, Joas, R, Joas, A, Dumez, B, Sepai, O, Exley, K & Aerts, D 2017, 'Urinary phthalate concentrations in mothers and their children in Ireland: Results of the DEMOCOPHES human biomonitoring study', International Journal of Environmental Research and Public Health, vol. 14, no. 12, 1456, pp. 1-12. https://doi.org/10.3390/ijerph14121456

APA

Cullen, E., Evans, D., Griffin, C., Burke, P., Mannion, R., Burns, D., ... Aerts, D. (2017). Urinary phthalate concentrations in mothers and their children in Ireland: Results of the DEMOCOPHES human biomonitoring study. International Journal of Environmental Research and Public Health, 14(12), 1-12. [1456]. https://doi.org/10.3390/ijerph14121456

Vancouver

Cullen E, Evans D, Griffin C, Burke P, Mannion R, Burns D et al. Urinary phthalate concentrations in mothers and their children in Ireland: Results of the DEMOCOPHES human biomonitoring study. International Journal of Environmental Research and Public Health. 2017 Dec;14(12):1-12. 1456. https://doi.org/10.3390/ijerph14121456

Author

Cullen, Elizabeth ; Evans, David ; Griffin, Chris ; Burke, Padraig ; Mannion, Rory ; Burns, Damien ; Flanagan, Andrew ; Kellegher, Ann ; Schoeters, Greet ; Govarts, Eva ; Biot, Pierre ; Casteleyn, Ludwine ; Castaño, Argelia ; Kolossa-Gehring, Marike ; Esteban, Marta ; Schwedler, Gerda ; Koch, Holger M. ; Angerer, Jürgen ; Knudsen, Lisbeth E. ; Joas, Reinhard ; Joas, Anke ; Dumez, Birgit ; Sepai, Ovnair ; Exley, Karen ; Aerts, Dominique. / Urinary phthalate concentrations in mothers and their children in Ireland : Results of the DEMOCOPHES human biomonitoring study. In: International Journal of Environmental Research and Public Health. 2017 ; Vol. 14, No. 12. pp. 1-12.

Bibtex

@article{6b92e179e0f94039b74214abecdc2a16,
title = "Urinary phthalate concentrations in mothers and their children in Ireland: Results of the DEMOCOPHES human biomonitoring study",
abstract = "Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the ‘Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale’ (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.",
keywords = "Endocrine disruptors, Exposure, Human biomonitoring, Phthalates",
author = "Elizabeth Cullen and David Evans and Chris Griffin and Padraig Burke and Rory Mannion and Damien Burns and Andrew Flanagan and Ann Kellegher and Greet Schoeters and Eva Govarts and Pierre Biot and Ludwine Casteleyn and Argelia Casta{\~n}o and Marike Kolossa-Gehring and Marta Esteban and Gerda Schwedler and Koch, {Holger M.} and J{\"u}rgen Angerer and Knudsen, {Lisbeth E.} and Reinhard Joas and Anke Joas and Birgit Dumez and Ovnair Sepai and Karen Exley and Dominique Aerts",
year = "2017",
month = "12",
doi = "10.3390/ijerph14121456",
language = "English",
volume = "14",
pages = "1--12",
journal = "International Journal of Environmental Research and Public Health",
issn = "1661-7827",
publisher = "MDPI AG",
number = "12",

}

RIS

TY - JOUR

T1 - Urinary phthalate concentrations in mothers and their children in Ireland

T2 - Results of the DEMOCOPHES human biomonitoring study

AU - Cullen, Elizabeth

AU - Evans, David

AU - Griffin, Chris

AU - Burke, Padraig

AU - Mannion, Rory

AU - Burns, Damien

AU - Flanagan, Andrew

AU - Kellegher, Ann

AU - Schoeters, Greet

AU - Govarts, Eva

AU - Biot, Pierre

AU - Casteleyn, Ludwine

AU - Castaño, Argelia

AU - Kolossa-Gehring, Marike

AU - Esteban, Marta

AU - Schwedler, Gerda

AU - Koch, Holger M.

AU - Angerer, Jürgen

AU - Knudsen, Lisbeth E.

AU - Joas, Reinhard

AU - Joas, Anke

AU - Dumez, Birgit

AU - Sepai, Ovnair

AU - Exley, Karen

AU - Aerts, Dominique

PY - 2017/12

Y1 - 2017/12

N2 - Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the ‘Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale’ (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.

AB - Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the ‘Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale’ (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.

KW - Endocrine disruptors

KW - Exposure

KW - Human biomonitoring

KW - Phthalates

UR - http://www.scopus.com/inward/record.url?scp=85036533494&partnerID=8YFLogxK

U2 - 10.3390/ijerph14121456

DO - 10.3390/ijerph14121456

M3 - Journal article

VL - 14

SP - 1

EP - 12

JO - International Journal of Environmental Research and Public Health

JF - International Journal of Environmental Research and Public Health

SN - 1661-7827

IS - 12

M1 - 1456

ER -

ID: 188444890