Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells. / Kristoffersen, Ulrik Sloth; Straalman, Kristina; Schmidt, Grethe; Klyver, Helle; Mortensen, Jann; Andersen, Peter Andreas; Chakera, Annette Hougaard; Kjaer, Andreas.

In: International Journal of Hyperthermia, Vol. 25, No. 1, 2009, p. 86-9.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Kristoffersen, US, Straalman, K, Schmidt, G, Klyver, H, Mortensen, J, Andersen, PA, Chakera, AH & Kjaer, A 2009, 'Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells', International Journal of Hyperthermia, vol. 25, no. 1, pp. 86-9. https://doi.org/10.1080/02656730802406145

APA

Kristoffersen, U. S., Straalman, K., Schmidt, G., Klyver, H., Mortensen, J., Andersen, P. A., ... Kjaer, A. (2009). Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells. International Journal of Hyperthermia, 25(1), 86-9. https://doi.org/10.1080/02656730802406145

Vancouver

Kristoffersen US, Straalman K, Schmidt G, Klyver H, Mortensen J, Andersen PA et al. Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells. International Journal of Hyperthermia. 2009;25(1):86-9. https://doi.org/10.1080/02656730802406145

Author

Kristoffersen, Ulrik Sloth ; Straalman, Kristina ; Schmidt, Grethe ; Klyver, Helle ; Mortensen, Jann ; Andersen, Peter Andreas ; Chakera, Annette Hougaard ; Kjaer, Andreas. / Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells. In: International Journal of Hyperthermia. 2009 ; Vol. 25, No. 1. pp. 86-9.

Bibtex

@article{1c3584805ff111dea8de000ea68e967b,
title = "Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells",
abstract = "PURPOSE: Hyperthermic isolated limb perfusion (HILP) is an effective method in the treatment of recurrent melanomas and soft tissue sarcomas. To avoid systemic toxicity, leakage from the limb perfusate into the systemic circulation is real-time monitored by administration of a radioactive agent to the limb circuit. This has made HILP safe for the patient. However, the radiation exposure to the surgical staff has never been measured and could be a limiting factor for the use of HILP. The purpose of the present study was to measure and evaluate the radiation exposure to the surgical staff performing HILP with (99m)Technetium labeled red blood cells. MATERIALS AND METHODS: Thirteen patients had HILP performed in 11 lower limbs and two upper limbs at our inpatient clinic between October 2006 and February 2007. The surgeon and nurse had thermoluminescence dosimetry (TLD) chips attached to the finger pulp and to the ring area of the left fourth finger, as well as an electronic dosimeter attached to the anterior lining of the trousers. The anesthesiologist and perfusion technologist also carried electronic dosimeters. RESULTS: The surgeon had the highest radioactive exposure with an average dose per procedure to the finger pulp of 16.2 microSv, to the ring area of 8.5 microSv, and to the abdominal wall of 4.2 +/- 0.6 microSv. CONCLUSIONS: HILP with (99m)technetium-labeled red blood cells does not constitute a safety risk to the operating team with respect to radioactive exposure. Routine dose monitoring of the staff or special precautions for fertile women are not necessary.",
author = "Kristoffersen, {Ulrik Sloth} and Kristina Straalman and Grethe Schmidt and Helle Klyver and Jann Mortensen and Andersen, {Peter Andreas} and Chakera, {Annette Hougaard} and Andreas Kjaer",
note = "Keywords: Chemotherapy, Cancer, Regional Perfusion; Erythrocytes; Female; Health Personnel; Humans; Neoplasms; Occupational Exposure; Radiometry; Radiopharmaceuticals; Technetium",
year = "2009",
doi = "10.1080/02656730802406145",
language = "English",
volume = "25",
pages = "86--9",
journal = "International Journal of Hyperthermia",
issn = "0265-6736",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - Radiation exposure to surgical staff during hyperthermic isolated limb perfusion with 99m Technetium labeled red blood cells

AU - Kristoffersen, Ulrik Sloth

AU - Straalman, Kristina

AU - Schmidt, Grethe

AU - Klyver, Helle

AU - Mortensen, Jann

AU - Andersen, Peter Andreas

AU - Chakera, Annette Hougaard

AU - Kjaer, Andreas

N1 - Keywords: Chemotherapy, Cancer, Regional Perfusion; Erythrocytes; Female; Health Personnel; Humans; Neoplasms; Occupational Exposure; Radiometry; Radiopharmaceuticals; Technetium

PY - 2009

Y1 - 2009

N2 - PURPOSE: Hyperthermic isolated limb perfusion (HILP) is an effective method in the treatment of recurrent melanomas and soft tissue sarcomas. To avoid systemic toxicity, leakage from the limb perfusate into the systemic circulation is real-time monitored by administration of a radioactive agent to the limb circuit. This has made HILP safe for the patient. However, the radiation exposure to the surgical staff has never been measured and could be a limiting factor for the use of HILP. The purpose of the present study was to measure and evaluate the radiation exposure to the surgical staff performing HILP with (99m)Technetium labeled red blood cells. MATERIALS AND METHODS: Thirteen patients had HILP performed in 11 lower limbs and two upper limbs at our inpatient clinic between October 2006 and February 2007. The surgeon and nurse had thermoluminescence dosimetry (TLD) chips attached to the finger pulp and to the ring area of the left fourth finger, as well as an electronic dosimeter attached to the anterior lining of the trousers. The anesthesiologist and perfusion technologist also carried electronic dosimeters. RESULTS: The surgeon had the highest radioactive exposure with an average dose per procedure to the finger pulp of 16.2 microSv, to the ring area of 8.5 microSv, and to the abdominal wall of 4.2 +/- 0.6 microSv. CONCLUSIONS: HILP with (99m)technetium-labeled red blood cells does not constitute a safety risk to the operating team with respect to radioactive exposure. Routine dose monitoring of the staff or special precautions for fertile women are not necessary.

AB - PURPOSE: Hyperthermic isolated limb perfusion (HILP) is an effective method in the treatment of recurrent melanomas and soft tissue sarcomas. To avoid systemic toxicity, leakage from the limb perfusate into the systemic circulation is real-time monitored by administration of a radioactive agent to the limb circuit. This has made HILP safe for the patient. However, the radiation exposure to the surgical staff has never been measured and could be a limiting factor for the use of HILP. The purpose of the present study was to measure and evaluate the radiation exposure to the surgical staff performing HILP with (99m)Technetium labeled red blood cells. MATERIALS AND METHODS: Thirteen patients had HILP performed in 11 lower limbs and two upper limbs at our inpatient clinic between October 2006 and February 2007. The surgeon and nurse had thermoluminescence dosimetry (TLD) chips attached to the finger pulp and to the ring area of the left fourth finger, as well as an electronic dosimeter attached to the anterior lining of the trousers. The anesthesiologist and perfusion technologist also carried electronic dosimeters. RESULTS: The surgeon had the highest radioactive exposure with an average dose per procedure to the finger pulp of 16.2 microSv, to the ring area of 8.5 microSv, and to the abdominal wall of 4.2 +/- 0.6 microSv. CONCLUSIONS: HILP with (99m)technetium-labeled red blood cells does not constitute a safety risk to the operating team with respect to radioactive exposure. Routine dose monitoring of the staff or special precautions for fertile women are not necessary.

U2 - 10.1080/02656730802406145

DO - 10.1080/02656730802406145

M3 - Journal article

VL - 25

SP - 86

EP - 89

JO - International Journal of Hyperthermia

JF - International Journal of Hyperthermia

SN - 0265-6736

IS - 1

ER -

ID: 12796722