Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease: A preliminary study

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Standard

Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease : A preliminary study. / Qayyum, Abbas A; Hasbak, Philip; Larsson, Henrik B W; Christensen, Thomas E; Ghotbi, Adam A; Mathiasen, Anders B; Vejlstrup, Niels G; Kjaer, Andreas; Kastrup, Jens.

In: European Journal of Radiology, Vol. 83, No. 7, 07.2014, p. 1120–1128.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Qayyum, AA, Hasbak, P, Larsson, HBW, Christensen, TE, Ghotbi, AA, Mathiasen, AB, Vejlstrup, NG, Kjaer, A & Kastrup, J 2014, 'Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease: A preliminary study', European Journal of Radiology, vol. 83, no. 7, pp. 1120–1128. https://doi.org/10.1016/j.ejrad.2014.04.004

APA

Qayyum, A. A., Hasbak, P., Larsson, H. B. W., Christensen, T. E., Ghotbi, A. A., Mathiasen, A. B., ... Kastrup, J. (2014). Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease: A preliminary study. European Journal of Radiology, 83(7), 1120–1128. https://doi.org/10.1016/j.ejrad.2014.04.004

Vancouver

Qayyum AA, Hasbak P, Larsson HBW, Christensen TE, Ghotbi AA, Mathiasen AB et al. Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease: A preliminary study. European Journal of Radiology. 2014 Jul;83(7):1120–1128. https://doi.org/10.1016/j.ejrad.2014.04.004

Author

Qayyum, Abbas A ; Hasbak, Philip ; Larsson, Henrik B W ; Christensen, Thomas E ; Ghotbi, Adam A ; Mathiasen, Anders B ; Vejlstrup, Niels G ; Kjaer, Andreas ; Kastrup, Jens. / Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease : A preliminary study. In: European Journal of Radiology. 2014 ; Vol. 83, No. 7. pp. 1120–1128.

Bibtex

@article{f97ee91e5f8d4311936eac5c64942427,
title = "Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease: A preliminary study",
abstract = "INTRODUCTION: Aim was to compare absolute myocardial perfusion using cardiac magnetic resonance imaging (CMRI) based on Tikhonov's procedure of deconvolution and rubidium-82 positron emission tomography (Rb-82 PET).MATERIALS AND METHODS: Fourteen patients with coronary artery stenosis underwent rest and adenosine stress imaging by 1.5-Tesla MR Scanner and a mCT/PET 64-slice Scanner. CMRI were analyzed based on Tikhonov's procedure of deconvolution without specifying an explicit compartment model using our own software. PET images were analyzed using standard clinical software. CMRI and PET data was compared with Spearman's rho and Bland-Altman analysis.RESULTS: CMRI results were strongly and significantly correlated with PET results for the absolute global myocardial perfusion differences (r=0.805, p=0.001) and for global myocardial perfusion reserve (MPR) (r=0.886, p<0.001). At vessel territorial level, CMRI results were also significantly correlated with absolute PET myocardial perfusion differences (r=0.737, p<0.001) and MPR (r=0.818, p<0.001). Each vessel territory had similar strong correlation for absolute myocardial perfusion differences (right coronary artery (RCA): r=0.787, p=0.001; left anterior descending artery (LAD): r=0.796, p=0.001; left circumflex artery (LCX): r=0.880, p<0.001) and for MPR (RCA: r=0.895, p<0.001; LAD: r=0.886, p<0.001; LCX: r=0.886, p<0.001).CONCLUSION: On a global and vessel territorial basis, CMRI-measured absolute myocardial perfusion differences and MPR were strongly and significantly correlated with the Rb-82 PET findings.",
keywords = "Adult, Aged, Blood Flow Velocity, Coronary Artery Disease, Coronary Circulation, Female, Humans, Magnetic Resonance Angiography, Magnetic Resonance Imaging, Cine, Male, Middle Aged, Myocardial Perfusion Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Reproducibility of Results, Rubidium Radioisotopes, Sensitivity and Specificity, Statistics as Topic",
author = "Qayyum, {Abbas A} and Philip Hasbak and Larsson, {Henrik B W} and Christensen, {Thomas E} and Ghotbi, {Adam A} and Mathiasen, {Anders B} and Vejlstrup, {Niels G} and Andreas Kjaer and Jens Kastrup",
note = "Copyright {\circledC} 2014 Elsevier Ireland Ltd. All rights reserved.",
year = "2014",
month = "7",
doi = "10.1016/j.ejrad.2014.04.004",
language = "English",
volume = "83",
pages = "1120–1128",
journal = "European Journal of Radiology",
issn = "0720-048X",
publisher = "Elsevier Ireland Ltd",
number = "7",

}

RIS

TY - JOUR

T1 - Quantification of myocardial perfusion using cardiac magnetic resonance imaging correlates significantly to rubidium-82 positron emission tomography in patients with severe coronary artery disease

T2 - A preliminary study

AU - Qayyum, Abbas A

AU - Hasbak, Philip

AU - Larsson, Henrik B W

AU - Christensen, Thomas E

AU - Ghotbi, Adam A

AU - Mathiasen, Anders B

AU - Vejlstrup, Niels G

AU - Kjaer, Andreas

AU - Kastrup, Jens

N1 - Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

PY - 2014/7

Y1 - 2014/7

N2 - INTRODUCTION: Aim was to compare absolute myocardial perfusion using cardiac magnetic resonance imaging (CMRI) based on Tikhonov's procedure of deconvolution and rubidium-82 positron emission tomography (Rb-82 PET).MATERIALS AND METHODS: Fourteen patients with coronary artery stenosis underwent rest and adenosine stress imaging by 1.5-Tesla MR Scanner and a mCT/PET 64-slice Scanner. CMRI were analyzed based on Tikhonov's procedure of deconvolution without specifying an explicit compartment model using our own software. PET images were analyzed using standard clinical software. CMRI and PET data was compared with Spearman's rho and Bland-Altman analysis.RESULTS: CMRI results were strongly and significantly correlated with PET results for the absolute global myocardial perfusion differences (r=0.805, p=0.001) and for global myocardial perfusion reserve (MPR) (r=0.886, p<0.001). At vessel territorial level, CMRI results were also significantly correlated with absolute PET myocardial perfusion differences (r=0.737, p<0.001) and MPR (r=0.818, p<0.001). Each vessel territory had similar strong correlation for absolute myocardial perfusion differences (right coronary artery (RCA): r=0.787, p=0.001; left anterior descending artery (LAD): r=0.796, p=0.001; left circumflex artery (LCX): r=0.880, p<0.001) and for MPR (RCA: r=0.895, p<0.001; LAD: r=0.886, p<0.001; LCX: r=0.886, p<0.001).CONCLUSION: On a global and vessel territorial basis, CMRI-measured absolute myocardial perfusion differences and MPR were strongly and significantly correlated with the Rb-82 PET findings.

AB - INTRODUCTION: Aim was to compare absolute myocardial perfusion using cardiac magnetic resonance imaging (CMRI) based on Tikhonov's procedure of deconvolution and rubidium-82 positron emission tomography (Rb-82 PET).MATERIALS AND METHODS: Fourteen patients with coronary artery stenosis underwent rest and adenosine stress imaging by 1.5-Tesla MR Scanner and a mCT/PET 64-slice Scanner. CMRI were analyzed based on Tikhonov's procedure of deconvolution without specifying an explicit compartment model using our own software. PET images were analyzed using standard clinical software. CMRI and PET data was compared with Spearman's rho and Bland-Altman analysis.RESULTS: CMRI results were strongly and significantly correlated with PET results for the absolute global myocardial perfusion differences (r=0.805, p=0.001) and for global myocardial perfusion reserve (MPR) (r=0.886, p<0.001). At vessel territorial level, CMRI results were also significantly correlated with absolute PET myocardial perfusion differences (r=0.737, p<0.001) and MPR (r=0.818, p<0.001). Each vessel territory had similar strong correlation for absolute myocardial perfusion differences (right coronary artery (RCA): r=0.787, p=0.001; left anterior descending artery (LAD): r=0.796, p=0.001; left circumflex artery (LCX): r=0.880, p<0.001) and for MPR (RCA: r=0.895, p<0.001; LAD: r=0.886, p<0.001; LCX: r=0.886, p<0.001).CONCLUSION: On a global and vessel territorial basis, CMRI-measured absolute myocardial perfusion differences and MPR were strongly and significantly correlated with the Rb-82 PET findings.

KW - Adult

KW - Aged

KW - Blood Flow Velocity

KW - Coronary Artery Disease

KW - Coronary Circulation

KW - Female

KW - Humans

KW - Magnetic Resonance Angiography

KW - Magnetic Resonance Imaging, Cine

KW - Male

KW - Middle Aged

KW - Myocardial Perfusion Imaging

KW - Positron-Emission Tomography

KW - Radiopharmaceuticals

KW - Reproducibility of Results

KW - Rubidium Radioisotopes

KW - Sensitivity and Specificity

KW - Statistics as Topic

U2 - 10.1016/j.ejrad.2014.04.004

DO - 10.1016/j.ejrad.2014.04.004

M3 - Journal article

VL - 83

SP - 1120

EP - 1128

JO - European Journal of Radiology

JF - European Journal of Radiology

SN - 0720-048X

IS - 7

ER -

ID: 138383999