Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes. / Flethøj, M.; Schwarzwald, C. C.; Haugaard, M. M.; Carstensen, H.; Kanters, J. K.; Olsen, L. H.; Buhl, R.

In: Journal of Veterinary Internal Medicine, Vol. 30, No. 4, 07.2016, p. 1260-1269.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Flethøj, M, Schwarzwald, CC, Haugaard, MM, Carstensen, H, Kanters, JK, Olsen, LH & Buhl, R 2016, 'Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes', Journal of Veterinary Internal Medicine, vol. 30, no. 4, pp. 1260-1269. https://doi.org/10.1111/jvim.13982

APA

Flethøj, M., Schwarzwald, C. C., Haugaard, M. M., Carstensen, H., Kanters, J. K., Olsen, L. H., & Buhl, R. (2016). Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes. Journal of Veterinary Internal Medicine, 30(4), 1260-1269. https://doi.org/10.1111/jvim.13982

Vancouver

Flethøj M, Schwarzwald CC, Haugaard MM, Carstensen H, Kanters JK, Olsen LH et al. Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes. Journal of Veterinary Internal Medicine. 2016 Jul;30(4):1260-1269. https://doi.org/10.1111/jvim.13982

Author

Flethøj, M. ; Schwarzwald, C. C. ; Haugaard, M. M. ; Carstensen, H. ; Kanters, J. K. ; Olsen, L. H. ; Buhl, R. / Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes. In: Journal of Veterinary Internal Medicine. 2016 ; Vol. 30, No. 4. pp. 1260-1269.

Bibtex

@article{5af5ae35ae554dcea7f846123b08739b,
title = "Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes",
abstract = "Background: Prolonged exercise in human athletes is associated with transient impairment of left ventricular (LV) function, known as cardiac fatigue. Cardiac effects of prolonged exercise in horses remain unknown.Objectives :To investigate the effects of prolonged exercise on LV systolic and diastolic function in horses.Animals: Twenty-six horses competing in 120–160 km endurance rides.Methods: Cross-sectional field study. Echocardiography was performed before and after rides, and the following morning, and included two-dimensional echocardiography, anatomical M-mode, pulsed-wave tissue Doppler imaging, and two-dimensional speckle tracking. Correlation between echocardiographic variables and cardiac troponin I was evaluated.Results: Early diastolic myocardial velocities decreased significantly in longitudinal (baseline: −17.4 ± 2.4cm/s; end of ride: −15.8 ± 3.2cm/s (P = .013); morning after: −15.4 ± 3.0cm/s (P = .0033)) and radial directions (−32.8 ± 3.4cm/s; −28.1 ± 5.8cm/s (P < .001); −26.4 ± 5.5cm/s (P < .001)). Early diastolic strain rates decreased significantly in longitudinal (1.58 ± 0.27s−1; 1.45 ± 0.26s−1 (P = .036); 1.41 ± 0.25s−1 (P = .013)) and circumferential directions (2.43 ± 0.29s−1; 1.96 ± 0.46s−1 (P < .001); 2.11 ± 0.32s−1 (P < .001)). Systolic variables showed ambiguous results. No correlations with serum cardiac troponin I concentrations were evident.Conclusions and Clinical Importance: Prolonged exercise in horses is associated with impaired LV diastolic function. Reduced ventricular filling persisted for 7–21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions. The clinical relevance of cardiac fatigue in horses remains uncertain.",
keywords = "Diastolic function, Echocardiography, Speckle tracking, Tissue Doppler imaging",
author = "M. Fleth{\o}j and Schwarzwald, {C. C.} and Haugaard, {M. M.} and H. Carstensen and Kanters, {J. K.} and Olsen, {L. H.} and R. Buhl",
year = "2016",
month = "7",
doi = "10.1111/jvim.13982",
language = "English",
volume = "30",
pages = "1260--1269",
journal = "Journal of Veterinary Internal Medicine",
issn = "0891-6640",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes

AU - Flethøj, M.

AU - Schwarzwald, C. C.

AU - Haugaard, M. M.

AU - Carstensen, H.

AU - Kanters, J. K.

AU - Olsen, L. H.

AU - Buhl, R.

PY - 2016/7

Y1 - 2016/7

N2 - Background: Prolonged exercise in human athletes is associated with transient impairment of left ventricular (LV) function, known as cardiac fatigue. Cardiac effects of prolonged exercise in horses remain unknown.Objectives :To investigate the effects of prolonged exercise on LV systolic and diastolic function in horses.Animals: Twenty-six horses competing in 120–160 km endurance rides.Methods: Cross-sectional field study. Echocardiography was performed before and after rides, and the following morning, and included two-dimensional echocardiography, anatomical M-mode, pulsed-wave tissue Doppler imaging, and two-dimensional speckle tracking. Correlation between echocardiographic variables and cardiac troponin I was evaluated.Results: Early diastolic myocardial velocities decreased significantly in longitudinal (baseline: −17.4 ± 2.4cm/s; end of ride: −15.8 ± 3.2cm/s (P = .013); morning after: −15.4 ± 3.0cm/s (P = .0033)) and radial directions (−32.8 ± 3.4cm/s; −28.1 ± 5.8cm/s (P < .001); −26.4 ± 5.5cm/s (P < .001)). Early diastolic strain rates decreased significantly in longitudinal (1.58 ± 0.27s−1; 1.45 ± 0.26s−1 (P = .036); 1.41 ± 0.25s−1 (P = .013)) and circumferential directions (2.43 ± 0.29s−1; 1.96 ± 0.46s−1 (P < .001); 2.11 ± 0.32s−1 (P < .001)). Systolic variables showed ambiguous results. No correlations with serum cardiac troponin I concentrations were evident.Conclusions and Clinical Importance: Prolonged exercise in horses is associated with impaired LV diastolic function. Reduced ventricular filling persisted for 7–21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions. The clinical relevance of cardiac fatigue in horses remains uncertain.

AB - Background: Prolonged exercise in human athletes is associated with transient impairment of left ventricular (LV) function, known as cardiac fatigue. Cardiac effects of prolonged exercise in horses remain unknown.Objectives :To investigate the effects of prolonged exercise on LV systolic and diastolic function in horses.Animals: Twenty-six horses competing in 120–160 km endurance rides.Methods: Cross-sectional field study. Echocardiography was performed before and after rides, and the following morning, and included two-dimensional echocardiography, anatomical M-mode, pulsed-wave tissue Doppler imaging, and two-dimensional speckle tracking. Correlation between echocardiographic variables and cardiac troponin I was evaluated.Results: Early diastolic myocardial velocities decreased significantly in longitudinal (baseline: −17.4 ± 2.4cm/s; end of ride: −15.8 ± 3.2cm/s (P = .013); morning after: −15.4 ± 3.0cm/s (P = .0033)) and radial directions (−32.8 ± 3.4cm/s; −28.1 ± 5.8cm/s (P < .001); −26.4 ± 5.5cm/s (P < .001)). Early diastolic strain rates decreased significantly in longitudinal (1.58 ± 0.27s−1; 1.45 ± 0.26s−1 (P = .036); 1.41 ± 0.25s−1 (P = .013)) and circumferential directions (2.43 ± 0.29s−1; 1.96 ± 0.46s−1 (P < .001); 2.11 ± 0.32s−1 (P < .001)). Systolic variables showed ambiguous results. No correlations with serum cardiac troponin I concentrations were evident.Conclusions and Clinical Importance: Prolonged exercise in horses is associated with impaired LV diastolic function. Reduced ventricular filling persisted for 7–21 hours despite normalization of biochemical indicators of hydration status, indicating that the observed changes were not entirely related to altered preload conditions. The clinical relevance of cardiac fatigue in horses remains uncertain.

KW - Diastolic function

KW - Echocardiography

KW - Speckle tracking

KW - Tissue Doppler imaging

U2 - 10.1111/jvim.13982

DO - 10.1111/jvim.13982

M3 - Journal article

VL - 30

SP - 1260

EP - 1269

JO - Journal of Veterinary Internal Medicine

JF - Journal of Veterinary Internal Medicine

SN - 0891-6640

IS - 4

ER -

ID: 165574268