Grønnegårdsvej 7, 1870 Frederiksberg C, 1-04
Stellate cells are one of the earliest known neurons to be affected in Alzheimer’s disease (AD) and reside in the layer II of the medial Entorhinal Cortex (EC) near the hippocampus. These stellate cells project to the hippocampus and play a role in spatial memory. Recent researches have shown the first accumulation of Amyloid beta in the EC. Little is known about the reason of the stellate cell being the first cell type affected in the disease. Further research is required to study this unique cell type, which would help to uncover new mechanisms that occur early and lead to new treatments in AD.