Thue W. Schwartz

Thue W. Schwartz

Professor

  • NNF Center for Basic Metabolic Research

  • Schwartz Group

    Blegdamsvej 3B, 2200 København N, Maersk Tower, Building: 07-6-85


  1. Published

    7TM receptorer - fra lugtesans og nye hormoner til HIV-infektion. / Schwartz, Thue W.

    In: Ugeskrift for læger, No. 159, 1997, p. 1239-1245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin. / Egerod, Kristoffer L; Engelstoft, Maja S; Grunddal, Kaare V; Nøhr, Mark K; Secher, Anna; Sakata, Ichiro; Pedersen, Jens; Windeløv, Johanne A; Füchtbauer, Ernst-Martin; Olsen, Jørgen; Sundler, Frank; Christensen, Jan P; Wierup, Nils; Olsen, Jesper V; Holst, Jens J; Zigman, Jeffrey M; Poulsen, Steen S; Schwartz, Thue W.

    In: Endocrinology, Vol. 153, No. 12, 01.12.2012, p. 5782-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A broadspectrum chemokine antagonist encoded by Karposis sarcoma associated herpes virus. / Kledal, Thomas N.; Rosenkilde, Mette Marie; Coulin, F.; Simmons, G.; Johnsen, A.H.; Alouani, S.; Schwartz, Thue W.; Poucer, C.A.; Lüttichau, H.R.; Gerstoft, J.; Clapham, P.R.; Clark-Lewis, I.; Wells, T.N.C.

    In: Kexue (Shanghai), No. 277, 1997, p. 1656-1659.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors. / Holst, Birgitte; Nygaard, Rie; Hansen, Louise Valentin; Bach, Anders; Engelstoft, Maja S; Petersen, Pia S; Frimurer, Thomas M; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 285, No. 6, 2010, p. 3973-85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A gut feeling for obesity: 7TM sensors on enteroendocrine cells. / Engelstoft, Maja Storm; Egerod, Kristoffer L; Holst, Birgitte; Schwartz, Thue W.

    In: Cell Metabolism, Vol. 8, No. 6, 2008, p. 447-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum. / Lüttichau, Hans Rudolf; J., Stine; Boesen, Thomas Peter; Johnsen, A.H.; Chantry, D.; Gerstoft, J.; Schwartz, Thue W.

    In: Journal of Experimental Medicine, No. 191, no. 1, 2000, p. 171-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6. / Lüttichau, Hans R; Clark-Lewis, Ian; Jensen, Peter Østrup; Moser, Claus; Gerstoft, Jan; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 278, No. Vol. 278 (13), 2003, p. 10928-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP). / Heydorn, Arne; Søndergaard, Birgitte P; Ersbøll, Bjarne; Holst, Birgitte; Nielsen, Finn Cilius; Haft, Carol Renfrew; Whistler, Jennifer; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 279, No. 52, 2004, p. 54291-303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39. / Storjohann, Laura; Holst, Birgitte; Schwartz, Thue W.

    In: Biochemistry, Vol. 47, No. 35, 2008, p. 9198-207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. / Hatse, Sigrid; Princen, Katrien; De Clercq, Erik; Rosenkilde, Mette M; Schwartz, Thue W; Hernandez-Abad, Pedro E; Skerlj, Renato T; Bridger, Gary J; Schols, Dominique.

    In: Biochemical Pharmacology, Vol. 70, No. 5, 2005, p. 752-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI. / Rosenkilde, Mette M; Andersen, Michael B; Nygaard, Rie; Frimurer, Thomas M; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 71, No. 3, 2006, p. 930-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors. / Schwartz, Thue W; Holst, Birgitte.

    In: Journal of Receptors and Signal Transduction, Vol. 26, No. 1-2, 2006, p. 107-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74. / Rosenkilde, M M; Kledal, T N; Bräuner-Osborne, Hans; Schwartz, T W.

    In: Journal of Biological Chemistry, Vol. 274, No. 2, 08.01.1999, p. 956-961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Allosteric enhancers, allosteric agonists and ago-allosteric modulators: where do they bind and how do they act? / Schwartz, Thue W; Holst, Birgitte.

    In: TIPS - Trends in Pharmacological Sciences, Vol. 28, No. 8, 2007, p. 366-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor. / Els, Sylvia; Schild, Enrico; Petersen, Pia Steen; Kilian, Tom-Marten; Mokrosinski, Jacek; Frimurer, Thomas M; Chollet, Constance; Schwartz, Thue W; Holst, Birgitte; Beck-Sickinger, Annette G.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 17, 13.09.2012, p. 7437-49.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    An enteroendocrine full package solution. / Schwartz, Thue W; Holst, Birgitte.

    In: Cell Metabolism, Vol. 11, No. 6, 2010, p. 445-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network. / Valentin-Hansen, Louise; Frimurer, Thomas M; Mokrosinski, Jacek; Holliday, Nicholas D; Schwartz, Thue W.

    In: The Journal of Biological Chemistry, Vol. 290, No. 40, 02.10.2015, p. 24495-508.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119. / Hassing, Helle A; Fares, Suzan; Larsen, Olav; Pad, Hamideh; Pedersen, Maria Hauge; Jones, Robert M; Schwartz, Thue W; Hansen, Harald S; Rosenkilde, Mette M.

    In: Biochemical Pharmacology, Vol. 119, No. 1, 26.08.2016, p. 66-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bidirectional GPR119 agonism requires peptide YY and glucose for activity in mouse and human colon mucosa. / Tough, Iain R; Forbes, Sarah; Herzog, Herbert; Jones, Robert M; Schwartz, Thue W; Cox, Helen M.

    In: Endocrinology, Vol. 159, No. 4, 19.02.2018, p. 1704-1717.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists. / Larson, D.L.; Jones, R.M.; Hjorth, Siv A.; Schwartz, Thue W.; Portoghese, P.S.

    In: Journal of Medicinal Chemistry, No. 43, no. 8, 2000, p. 1573-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics. / Park, Minyoung; Sivertsen, Bjørn Behrens; Els-Heindl, Sylvia; Huber, Thomas; Holst, Birgitte; Beck-Sickinger, Annette G.; Schwartz, Thue W.; Sakmar, Thomas P.

    In: Chemistry & Biology, Vol. 22, No. 11, 19.11.2015, p. 1431-1436.

    Research output: Contribution to journalLetterResearchpeer-review

  22. Published

    Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors. / Tian, He; Naganathan, Saranga; Kazmi, Manija A; Schwartz, Thue W.; Sakmar, Thomas P; Huber, Thomas.

    In: ChemBioChem, Vol. 15, No. 12, 18.08.2014, p. 1820-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    C-terminal KDEL-modified cystatin C is retained in transfected CHO cells. / Johansen, Teit Eliot; Vogel, Charlotte Katrine; Schwartz, Thue W.

    In: Biochemical and Biophysical Research Communications, Vol. 172, No. 3, 1990, p. 1384-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor. / Casarosa, Paola; Waldhoer, Maria; LiWang, Patricia J; Vischer, Henry F; Kledal, Thomas; Timmerman, Henk; Schwartz, Thue W; Smit, Martine J; Leurs, Rob.

    In: Journal of Biological Chemistry, Vol. 280, No. 5, 2005, p. 3275-3285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection. / Klasse, P.J.; Rosenkilde, Mette Marie; Signoret, N.; Pelchen-Matthews, A.; Schwartz, Thue W.; Marsh, M.

    In: Journal of Virology, No. 73, no. 9, 1999, p. 7453-7466.

    Research output: Contribution to journalJournal articleResearchpeer-review

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