Thue W. Schwartz

Thue W. Schwartz

Professor

  • Schwartz Group

    Blegdamsvej 3B, 2200 København N, Maersk Tower, Building: 07-6-85

  • Nutrient and Metabolite Sensing

    Blegdamsvej 3B, Building: 07-6-85

    2200 København N

    Denmark


  1. 2007
  2. Published

    Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer. / Jorgensen, Rasmus; Holliday, Nicholas D; Hansen, Jakob L; Vrecl, Milka; Heding, Anders; Schwartz, Thue W; Elling, Christian E.

    In: Molecular Pharmacology, Vol. 73, No. 2, 2007, p. 349-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s). / Jorgensen, Rasmus; Kubale, Valentina; Vrecl, Milka; Schwartz, Thue W; Elling, Christian E.

    In: Journal of Pharmacology and Experimental Therapeutics, Vol. 322, No. 1, 2007, p. 148-54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3. / Lüttichau, Hans R; Johnsen, Anders H; Jurlander, Jesper; Rosenkilde, Mette M; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 282, No. 24, 2007, p. 17794-805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor. / Rosenkilde, Mette M; Gerlach, Lars-Ole; Hatse, Sigrid; Skerlj, Renato T; Schols, Dominique; Bridger, Gary J; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 282, No. 37, 2007, p. 27354-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Allosteric enhancers, allosteric agonists and ago-allosteric modulators: where do they bind and how do they act? / Schwartz, Thue W; Holst, Birgitte.

    In: TIPS - Trends in Pharmacological Sciences, Vol. 28, No. 8, 2007, p. 366-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2006
  8. Published

    Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation. / Elling, Christian E; Frimurer, Thomas M; Gerlach, Lars-Ole; Jorgensen, Rasmus; Holst, Birgitte; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 281, No. 25, 2006, p. 17337-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    GPR39 signaling is stimulated by zinc ions but not by obestatin. / Holst, Birgitte; Egerod, Kristoffer L; Schild, Enrico; Vickers, Steve P; Cheetham, Sharon; Gerlach, Lars-Ole; Storjohann, Laura; Stidsen, Carsten E; Jones, Rob; Beck-Sickinger, Annette G; Schwartz, Thue W.

    In: Endocrinology, Vol. 148, No. 1, 2006, p. 13-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor. / Holst, Birgitte; Lang, Manja; Brandt, Erik; Bach, Anders; Howard, Andrew; Frimurer, Thomas M; Beck-Sickinger, Annette; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 70, No. 3, 2006, p. 936-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Ghrelin receptor mutations--too little height and too much hunger. / Holst, Birgitte; Schwartz, Thue W.

    In: Journal of Clinical Investigation, Vol. 116, No. 3, 2006, p. 637-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR. / Nygaard, Rie; Nielbo, Steen; Schwartz, Thue W; Poulsen, Flemming M.

    In: Biochemistry, Vol. 45, No. 27, 2006, p. 8350-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    GluVII : 06 - a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors. / Rosenkilde, M.M.; Schwartz, T.W.

    In: Current Topics in Medicinal Chemistry, Vol. 6, No. 13, 2006, p. 1319-1333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI. / Rosenkilde, Mette M; Andersen, Michael B; Nygaard, Rie; Frimurer, Thomas M; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 71, No. 3, 2006, p. 930-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V. / Rosenkilde, Mette M; David, Ralf; Oerlecke, Ilka; Benned-Jensen, Tau; Geumann, Ulf; Beck-Sickinger, Anette G; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 70, No. 6, 2006, p. 1892-901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors. / Rosenkilde, Mette M; Schwartz, Thue W.

    In: Current Topics in Medicinal Chemistry, Vol. 6, No. 13, 2006, p. 1319-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity. / Rosenkilde, Mette M; Benned-Jensen, Tau; Holst, Peter J; Kledal, Thomas N; Lüttichau, Hans R; Larsen, Jørgen K; Christensen, Jan P; Schwartz, Thue W; Andersen, Helene.

    In: Journal of Biological Chemistry, Vol. 281, No. 19, 2006, p. 13199-208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors. / Schwartz, Thue W; Holst, Birgitte.

    In: Journal of Receptors and Signal Transduction, Vol. 26, No. 1-2, 2006, p. 107-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Molecular mechanism of 7TM receptor activation--a global toggle switch model. / Schwartz, Thue W; Frimurer, Thomas M; Holst, Birgitte; Rosenkilde, Mette M; Elling, Christian E.

    In: Annual Review of Pharmacology and Toxicology, Vol. 46, 2006, p. 481-519.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2005
  21. Published

    CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor. / Casarosa, Paola; Waldhoer, Maria; LiWang, Patricia J; Vischer, Henry F; Kledal, Thomas; Timmerman, Henk; Schwartz, Thue W; Smit, Martine J; Leurs, Rob.

    In: Journal of Biological Chemistry, Vol. 280, No. 5, 2005, p. 3275-3285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release. / Hamid, Y H; Vissing, H; Holst, B; Urhammer, S A; Pyke, C; Hansen, S K; Glümer, C; Borch-Johnsen, K; Jørgensen, T; Schwartz, T W; Pedersen, O; Hansen, T.

    In: Diabetic Medicine, Vol. 22, No. 1, 2005, p. 74-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor. / Hatse, Sigrid; Princen, Katrien; De Clercq, Erik; Rosenkilde, Mette M; Schwartz, Thue W; Hernandez-Abad, Pedro E; Skerlj, Renato T; Bridger, Gary J; Schols, Dominique.

    In: Biochemical Pharmacology, Vol. 70, No. 5, 2005, p. 752-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling. / Holst, Birgitte; Brandt, Erik; Bach, Anders; Heding, Anders; Schwartz, Thue W.

    In: Molecular Endocrinology, Vol. 19, No. 9, 2005, p. 2400-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma. / Jensen, Kristian K; Manfra, Denise J; Grisotto, Marcos G; Martin, Andrea P; Vassileva, Galya; Kelley, Kevin; Schwartz, Thue W; Lira, Sergio A.

    In: Journal of Immunology, Vol. 174, No. 6, 2005, p. 3686-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposis sarcoma. / Jensen, Kristian Kirk; Manfra, D.J.; Grisotto, M.G.; Martin, A.P.; Vassileva, G.; Kelley, K.; Schwartz, Thue W.; Lira, Sergio A.

    In: Journal of Immunology, No. Vol. 174, no. 6, 2005, p. 3686-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Characterizaton of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype. / Jorgensen, R.; Martini, Lene; Schwartz, Thue W.; Elling, Christian E.

    In: Molecular Endocrinology, No. Vol. 19, no.3, 2005, p. 812-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype. / Jorgensen, Rasmus; Martini, Lene; Schwartz, Thue W; Elling, Christian E.

    In: Molecular Endocrinology, Vol. 19, No. 3, 2005, p. 812-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11601