Thue W. Schwartz

Thue W. Schwartz

Professor

  • Schwartz Group

    Blegdamsvej 3B, 2200 København N, Maersk Tower, Building: 07-6-85

  • Nutrient and Metabolite Sensing

    Blegdamsvej 3B, Building: 07-6-85

    2200 København N

    Denmark


  1. 2016
  2. Published

    Opposite Regulation of Ghrelin and Glucagon-like Peptide-1 by Metabolite G-Protein-Coupled Receptors. / Engelstoft, M S; Schwartz, T W.

    In: Trends in Endocrinology and Metabolism, Vol. 27, No. 9, 09.2016, p. 665-675.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism. / Grunddal, Kaare Villum; Ratner, Cecilia F; Svendsen, Berit; Sommer, Felix; Engelstoft, Maja S; Madsen, Andreas N; Pedersen, Jens; Nøhr, Mark K; Egerod, Kristoffer L; Nawrocki, Andrea R; Kowalski, Timothy; Howard, Andrew D; Poulsen, Steen Seier; Offermanns, Stefan; Bäckhed, Gert Fredrik; Holst, Jens J; Holst, Birgitte; Schwartz, Thue W.

    In: Endocrinology, Vol. 157, No. 1, en20151600, 01.2016, p. 176-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor. / Hassing, H A; Engelstoft, M S; Sichlau, R M; Madsen, A N; Rehfeld, J F; Pedersen, J; Jones, R M; Holst, J J; Schwartz, T W; Rosenkilde, M M; Hansen, Harald S.

    In: BioFactors, Vol. 42, No. 6, 2016, p. 665-673.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119. / Hassing, Helle A; Fares, Suzan; Larsen, Olav; Pad, Hamideh; Pedersen, Maria Hauge; Jones, Robert M; Schwartz, Thue W; Hansen, Harald S; Rosenkilde, Mette M.

    In: Biochemical Pharmacology, Vol. 119, No. 1, 26.08.2016, p. 66-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    GLP1- and GIP-producing cells rarely overlap and differ by bombesin receptor-2 expression and responsiveness. / Svendsen, Berit; Pais, Ramona; Engelstoft, Maja S; Milev, Nikolay B; Richards, Paul; Christiansen, Charlotte B; Egerod, Kristoffer L; Jensen, Signe Marie; Habib, Abdella M; Gribble, Fiona M; Schwartz, Thue W; Reimann, Frank; Holst, Jens J.

    In: Journal of Endocrinology, Vol. 228, No. 1, 2016, p. 39-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice. / Thieme, V; Jolly, N; Madsen, A N; Bellmann-Sickert, K; Schwartz, T W; Holst, B; Cox, H M; Beck-Sickinger, A G.

    In: British Journal of Pharmacology, Vol. 173, No. 22, 11.2016, p. 3208-3221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population. / Vestmar, Marie A; Galijatovic, Ehm Astrid Andersson; Christensen, Charlotte Riis; Pedersen, Maria Hauge; Glümer, Charlotte; Linneberg, Allan; Witte, Daniel R; Jørgensen, Marit E; Christensen, Cramer; Brandslund, Ivan; Lauritzen, Torsten ; Pedersen, Oluf; Holst, Birgitte; Grarup, Niels; Schwartz, Thue W; Hansen, Torben.

    In: Journal of Medical Genetics, Vol. 53, No. 9, 09.2016, p. 616-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2015
  11. Published

    The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration. / Cornelia Peeters, Miriam; Fokkelman, Michiel; Boogaard, Bob; Egerod, Kristoffer L; van de Water, Bob; IJzerman, Ad P; Schwartz, Thue W.

    In: Cellular Signalling, Vol. 27, No. 12, 12.2015, p. 2579-88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells. / Egerod, Kristoffer L; Engelstoft, Maja S; Lund, Mari L; Grunddal, Kaare V; Zhao, Mirabella; Barir-Jensen, Dominique; Nygaard, Eva B; Petersen, Natalia; Holst, Jens J; Schwartz, Thue W.

    In: Endocrinology, Vol. 156, No. 11, 11.2015, p. 3909-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Research Resource : A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells. / Engelstoft, Maja S; Lund, Mari L; Grunddal, Kaare V; Egerod, Kristoffer L; Osborne-Lawrence, Sherri; Poulsen, Steen Seier; Zigman, Jeffrey M; Schwartz, Thue W.

    In: Molecular endocrinology (Baltimore, Md.), Vol. 29, No. 11, 11.2015, p. 1658-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors. / Hamann, Jörg; Aust, Gabriela; Araç, Demet; Engel, Felix B; Formstone, Caroline; Fredriksson, Robert; Hall, Randy A; Harty, Breanne L; Kirchhoff, Christiane; Knapp, Barbara; Krishnan, Arunkumar; Liebscher, Ines; Lin, Hsi-Hsien; Martinelli, David C; Monk, Kelly R; Cornelia Peeters, Miriam; Piao, Xianhua; Prömel, Simone; Schöneberg, Torsten; Schwartz, Thue W; Singer, Kathleen; Stacey, Martin; Ushkaryov, Yuri A; Vallon, Mario; Wolfrum, Uwe; Wright, Mathew W; Xu, Lei; Langenhan, Tobias; Schiöth, Helgi B.

    In: Pharmacological Reviews, Vol. 67, No. 2, 04.2015, p. 338-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The MicroRNA Repertoire in Enteroendocrine Cells : Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage. / Knudsen, Lina A; Petersen, Natalia; Schwartz, Thue W; Egerod, Kristoffer L.

    In: Endocrinology, Vol. 156, No. 11, 11.2015, p. 3971-83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1. / Manfra, Ornella; Van Craenenbroeck, Kathleen; Skieterska, Kamila; Frimurer, Thomas; Schwartz, Thue W.; Levy, Finn Olav; Andressen, Kjetil Wessel.

    In: A C S Chemical Neuroscience, Vol. 6, No. 7, 07.2015, p. 1206–1218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Ghrelin. / Mueller, T. D.; Nogueiras, R.; Andermann, M. L.; Andrews, Z. B.; Anker, S. D.; Argente, J.; Batterham, R. L.; Benoit, S. C.; Bowers, C. Y.; Broglio, F.; Casanueva, F. F.; D'Alessio, D.; Depoortere, I.; Geliebter, A.; Ghigo, E.; Cole, P. A.; Cowley, M.; Cummings, D. E.; Dagher, A.; Diano, S.; Dickson, S. L.; Dieguez, C.; Granata, R.; Grill, H. J.; Grove, K.; Habegger, K. M.; Heppner, K.; Heiman, M. L.; Holsen, L.; Holst, B.; Inui, A.; Jansson, J. O.; Kirchner, H.; Korbonits, M.; Laferrere, B.; LeRoux, C. W.; Lopez, M.; Morin, S.; Nakazato, M.; Nass, R.; Perez-Tilve, D.; Pfluger, P. T.; Schwartz, T. W.; Seeley, R. J.; Sleeman, M.; Sun, Y.; Sussel, L.; Tong, J.; Thorner, M. O.; van der Lely, A. J.; van der Ploeg, L. H. T.; Zigman, J. M.; Kojima, M.; Kangawa, K.; Smith, R. G.; Horvath, T.; Tschoep, M. H.

    In: Molecular Metabolism, Vol. 4, No. 6, 06.2015, p. 437-460.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening. / Norn, Christoffer; Pedersen, Maria Hauge; Engelstoft, Maja S.; Kim, Sun Hee; Lehmann, Juerg; Jones, Robert M.; Schwartz, Thue W.; Frimurer, Thomas M.

    In: Structure, Vol. 23, No. 12, 2015, p. 2377-2386.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia. / Nøhr, Mark Klitgaard; Egerod, K L; Christiansen, S H; Gille, A; Offermanns, S; Schwartz, Thue W.; Møller, M.

    In: Neuroscience, Vol. 290, 02.04.2015, p. 126-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics. / Park, Minyoung; Sivertsen, Bjørn Behrens; Els-Heindl, Sylvia; Huber, Thomas; Holst, Birgitte; Beck-Sickinger, Annette G.; Schwartz, Thue W.; Sakmar, Thomas P.

    In: Chemistry & Biology, Vol. 22, No. 11, 19.11.2015, p. 1431-1436.

    Research output: Contribution to journalLetterResearchpeer-review

  21. Published

    GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo. / Pedersen, Maria Hauge; Bentsen, Marie Aare; Husted, Anna S; Ekberg, Jeppe P; Wright, Michael J; Di Salvo, Jerry; Weinglass, Adam B; Engelstoft, Maja Storm; Madsen, Andreas N; Lückmann, Michael; Miller, Michael W; Trujillo, Maria E; Frimurer, Thomas M; Holst, Birgitte; Howard, Andrew D; Schwartz, Thue W.

    In: Molecular Metabolism, Vol. 4, No. 1, 01.2015, p. 3-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network. / Valentin-Hansen, Louise; Frimurer, Thomas M; Mokrosinski, Jacek; Holliday, Nicholas D; Schwartz, Thue W.

    In: The Journal of Biological Chemistry, Vol. 290, No. 40, 02.10.2015, p. 24495-508.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system : new aspects on Alzheimer's disease. / Ádori, Csaba; Glück, Laura; Barde, Swapnali; Yoshitake, Takashi; Kovacs, Gabor G; Mulder, Jan; Maglóczky, Zsófia; Havas, László; Bölcskei, Kata; Mitsios, Nicholas; Uhlén, Mathias; Szolcsányi, János; Kehr, Jan; Rönnbäck, Annica; Schwartz, Thue; Rehfeld, Jens F; Harkany, Tibor; Palkovits, Miklós; Schulz, Stefan; Hökfelt, Tomas.

    In: Acta Neuropathologica, Vol. 129, No. 4, 04.2015, p. 541-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2014
  25. Published

    Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119. / Engelstoft, Maja Storm; Norn, C; Pedersen, Maria Hauge; Holliday, N D; Elster, L; Lehmann, J; Jones, R M; Frimurer, T M; Schwartz, T W.

    In: British Journal of Pharmacology, Vol. 171, No. 24, 12.2014, p. 5774-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo. / Panaro, Brandon L; Tough, Iain R; Engelstoft, Maja S; Matthews, Robert T; Digby, Gregory J; Møller, Cathrine L; Svendsen, Berit; Gribble, Fiona; Reimann, Frank; Holst, Jens Juul; Holst, Birgitte; Schwartz, Thue W; Cox, Helen M; Cone, Roger D.

    In: Cell Metabolism, Vol. 20, No. 6, 02.12.2014, p. 1018-29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure and appetite in overweight men. / Schmidt, Julie Berg; Gregersen, Nikolaj Ture; Pedersen, Sue D; Arentoft, Johanne L; Ritz, Christian; Schwartz, Thue W.; Holst, Jens Juul; Astrup, Arne; Sjödin, Anders Mikael.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 306, No. 11, 2014, p. E1248-E1256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors. / Tian, He; Naganathan, Saranga; Kazmi, Manija A; Schwartz, Thue W.; Sakmar, Thomas P; Huber, Thomas.

    In: ChemBioChem, Vol. 15, No. 12, 18.08.2014, p. 1820-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11601