Susan Weng Larsen
Associate Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, Building: 13-5-516
2100 København Ø
- 2019
- Published
Citrem-phosphatidylcholine nano-self-assemblies: solubilization of bupivacaine and its role in triggering a colloidal transition from vesicles to cubosomes and hexosomes. / Prajapati, Rama; Larsen, Susan Weng; Yaghmur, Anan.
In: Physical Chemistry Chemical Physics, Vol. 21, No. 27, 21.07.2019, p. 15142-15150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transport characteristics in a novel in vitro release model for testing the performance of intra-articular injectables. / Mertz, Nina; Ostergaard, Jesper; Yaghmur, Anan; Larsen, Susan Weng.
In: International Journal of Pharmaceutics, Vol. 566, 20.07.2019, p. 445-453.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
UV-vis Imaging of Piroxicam Supersaturation, Precipitation, and Dissolution in a Flow-Through Setup. / Sun, Yu; Chapman, Alex; Larsen, Susan W.; Jensen, Henrik; Petersen, Nickolaj J.; Goodall, David M.; Ostergaard, Jesper.
In: Analytical Chemistry, Vol. 90, No. 11, 05.06.2018, p. 6413-6418.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concomitant monitoring of implant formation and drug release of in situ forming poly (lactide-co-glycolide acid) implants in a hydrogel matrix mimicking the subcutis using UV–vis imaging. / Sun, Yu; Jensen, Henrik; Petersen, Nickolaj J.; Larsen, Susan Weng; Østergaard, Jesper.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 150, 2018, p. 95-106.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Phase separation of in situ forming poly (lactide-co-glycolide acid) implants investigated using a hydrogel-based subcutaneous tissue surrogate and UV-vis imaging. / Sun, Yu; Jensen, Henrik; Petersen, Nickolaj J; Larsen, Susan W; Østergaard, Jesper.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 145, 25.10.2017, p. 682-691.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Long-Acting Diclofenac Ester Prodrugs for Joint Injection : Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension. / Mertz, Nina; Larsen, Susan Weng; Kristensen, Jesper; Østergaard, Jesper; Larsen, Claus.
In: Journal of Pharmaceutical Sciences, Vol. 105, No. 10, 27.07.2016, p. 3079–3087.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics : Implications for Drug Delivery. / Ye, Fengbin; Baldursdottir, Stefania; Hvidt, Søren; Jensen, Henrik; Larsen, Susan W; Yaghmur, Anan; Larsen, Claus ; Østergaard, Jesper.
In: Molecular Pharmaceutics, Vol. 13, No. 3, 07.03.2016, p. 819-28.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Microenvironmental pH measurement during sodium naproxenate dissolution in acidic medium by UV/vis imaging. / Ostergaard, Jesper; Jensen, Henrik; Larsen, Susan W; Larsen, Claus; Lenke, Jim.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 100, 17.08.2014, p. 290-293.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure. / Nilsson, Christa; Ostergaard, Jesper; Larsen, Susan Weng; Larsen, Claus; Urtti, Arto; Yaghmur, Anan.
In: Langmuir : the ACS journal of surfaces and colloids, Vol. 30, No. 22, 10.06.2014, p. 6398-6407.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of Action of Lung Damage Caused by a Nanofilm Spray Product. / Larsen, Søren T.; Dallot, Constantin; Larsen, Susan W; Rose, Fabrice; Poulsen, Steen Seier; Nørgaard, Asger W; Hansen, Jitka S; Sørli, Jorid B; Nielsen, Gunnar D; Foged, Camilla.
In: Toxicological Sciences, Vol. 140, No. 2, 25.05.2014, p. 436-444.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection. / Thing, Mette; Agårdh, Li; Larsen, Susan; Rasmussen, Rune; Pallesen, Jakob; Mertz, Nina; Kristensen, Jesper Langgaard; Hansen, Martin; Ostergaard, Jesper; Larsen, Claus Selch.
In: Journal of Pharmaceutical Sciences, Vol. 103, No. 12, 2014, p. 4021–4029.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications. / Nilsson, Christa; Barrios-Lopez, Brianda; Kallinen, Annukka; Laurinmäki, Pasi; Butcher, Sarah J; Raki, Mari; Weisell, Janne; Bergström, Kim; Larsen, Susan Weng; Ostergaard, Jesper; Larsen, Claus; Urtti, Arto; Airaksinen, Anu J; Yaghmur, Anan.
In: Biomaterials, Vol. 34, No. 33, 07.08.2013, p. 8491-8503.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat. / Thing, Mette; Lu, Yi; Agårdh, Li; Larsen, Claus Selch; Ostergaard, Jesper; He, Wei; Wu, Wei; Larsen, Frank; Larsen, Susan Weng.
In: International Journal of Pharmaceutics, Vol. 451, No. 1-2, 15.07.2013, p. 34-40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of Amino Acid and Dipeptide beta-Naphthylamide Derivatives with Hyaluronic Acid and Human Serum Albumin Studied by Capillary Electrophoresis Frontal Analysis. / Ye, Fengbin; Xie, Yuanyi; Jensen, Henrik; Larsen, Susan Weng; Yaghmur, Anan; Larsen, Claus; Ostergaard, Jesper.
In: Chromatographia, Vol. 76, No. 1-2, 01.2013, p. 49-57.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ forming drug delivery systems based on lyotropic liquid crystalline phases : structural characterization and release properties. / Yaghmur, Anan; Rappolt, M.; Larsen, Susan Weng.
In: Journal of Drug Delivery Science and Technology, Vol. 23, No. 4, 2013, p. 325-332.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Medicindepot dannes efter injektion i leddet. / Larsen, Susan Weng; Thing, Mette Agergaard; Østergaard, Jesper; Kristensen, Jesper Langgaard; Hansen, Martin; Larsen, Claus Selch.
In: Lægemiddelforskning, Vol. 2013, 2013, p. 38-40.Research output: Contribution to journal › Journal article › Research
- Published
Physicochemical profiling of drug candidates using capillary-based techniques. / Jensen, Henrik; Larsen, Susan Weng; Larsen, Claus Selch; Østergaard, Jesper.
In: Journal of Drug Delivery Science and Technology, Vol. 23, 2013, p. 333-345.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of in vitro release models in the design of sustained and localized drug delivery systems for subcutaneous and intra-articular administration. / Larsen, Susan Weng; Østergaard, Jesper; Yaghmur, Anan; Jensen, Henrik; Larsen, Claus.
In: Journal of Drug Delivery Science and Technology, Vol. 23, 2013, p. 333-345.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
In vitro release from oil injectabels for intra-articular administration : importance of interfacial area, diffusivity and partitioning. / Thing, Mette Agergaard; Larsen, Claus Selch; Østergaard, Jesper; Jensen, Henrik; Larsen, Susan Weng.
In: European Journal of Pharmaceutical Sciences, Vol. 45, No. 3, 2012, p. 351-357.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions : the effect of lipid composition. / Yaghmur, Anan; Rappolt, Michael; Østergaard, Jesper; Larsen, Claus Selch; Larsen, Susan Weng.
In: Langmuir, Vol. 28, No. 5, 2012, p. 2881-2889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem. / Nilsson, Christa; Edwards, Katarina; Eriksson, Johnny; Larsen, Susan Weng; Østergaard, Jesper; Larsen, Claus Selch; Urtti, Arto; Yaghmur, Anan.
In: Langmuir, Vol. 28, No. 32, 2012, p. 11755-11766.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug release into hydrogel-based subcutaneous surrogates studied by UV imaging. / Ye, Fengbin; Larsen, Susan Weng; Yaghmur, Anan; Jensen, Henrik; Larsen, Claus Selch; Ostergaard, Jesper.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 71, 2012, p. 27-34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis. / Ye, Fengbin; Jensen, Henrik; Larsen, Susan Weng; Yaghmur, Anan; Larsen, Claus Selch; Østergaard, Jesper.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 61, 2012, p. 176-183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of concomitant drug release from oil vehicles using drug-prodrug combinations to achieve sustained balanced analgesia after joint installation. / Thing, Mette; Jensen, Sabrine Smedegaard; Larsen, Claus Selch; Ostergaard, Jesper; Larsen, Susan Weng.
In: International Journal of Pharmaceutics, Vol. 439, No. 1-2, 2012, p. 246-53.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix. / Ye, Fengbin; Larsen, Susan Weng; Yaghmur, Anan; Jensen, Henrik; Larsen, Claus Selch; Østergaard, Jesper.
In: European Journal of Pharmaceutical Sciences, Vol. 46, No. 1-2, 2012, p. 72-78.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging. / Ostergaard, Jesper; Ye, Fengbin; Rantanen, Jukka; Yaghmur, Anan; Larsen, Susan Weng; Larsen, Claus Selch; Jensen, Henrik.
In: Journal of Pharmaceutical Sciences, Vol. 100, No. 8, 08.2011, p. 3405-3410.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time UV imaging of drug diffusion and release from Pluronic F127 hydrogels. / Ye, Fengbin; Yaghmur, Anan; Jensen, Henrik; Larsen, Susan W.; Larsen, Claus; Ostergaard, Jesper.
In: European Journal of Pharmaceutical Sciences, Vol. 43, No. 4, 17.07.2011, p. 236-243.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo characteristics of celecoxib in situ formed suspensions for intra-articular administration. / Larsen, Susan Weng; Frost, Anna Buus; Østergaard, Jesper; Thomsen, Maj Halling; Jacobsen, Stine; Skonberg, Christian; Hansen, Steen Honore'; Jensen, Henrik Michael Elvang; Larsen, Claus Selch.
In: Journal of Pharmaceutical Sciences, Vol. 100, No. 10, 2011, p. 4330-4337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ characterization of lipidic bupivacaine-loaded formulations. / Yaghmur, Anan; Larsen, Susan Weng; Schmitt, Mechthild; Østergaard, Jesper; Larsen, Claus Selch; Jensen, Henrik; Urtti, Arto; Rappolt, Michael .
In: Soft Matter, Vol. 7, 2011, p. 8291-8295.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intra-articular injection of morphine to the horse: Establishment of an in vitro-in vivo relationship. / Frost, Anna Buus; Lindegaard, Casper; Larsen, Frank; Østergaard, Jesper; Larsen, Susan Weng; Larsen, Claus Selch.
In: Drug Development and Industrial Pharmacy, Vol. 37, No. 9, 2011, p. 1043-1048.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physicochemical characteristics and in vitro release from oil-based vehicles of peptidomimetics : parenteral depots for intra-articular administration. / Pedersen, Brian Thoning; Østergaard, Jesper; Larsen, Susan Weng; Cornett, Claus; Ankersen, Michael; Larsen, Claus Selch.
In: Drug Development and Industrial Pharmacy, Vol. 37, No. 1, 2011, p. 62-71.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: Administration of sodium diatrizoate to the horse. / Frost, Anna Buus; Larsen, Frank; Østergaard, Jesper; Larsen, Susan Weng; Lindegaard, Casper; Hansen, Helle Rüsz; Larsen, Claus Selch.
In: European Journal of Pharmaceutical Sciences, Vol. 41, 2010, p. 10-15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time UV imaging of nicotin release from transdermal patch. / Østergaard, Jesper; Meng-Lund, Emil; Larsen, Susan Weng; Larsen, Claus Selch; Petersson, Karsten; Lenke, James; Jensen, Henrik.
In: Pharmaceutical Research, Vol. 27, 2010, p. 2614-2623.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse. / Frost, Anna Buus; Larsen, Frank; Larsen, Susan Weng; Østergaard, Jesper; Thomsen, Maj Halling; Stürup, Stefan; Andersen, Pia Haubro; Larsen, Claus Selch.
In: Pharmaceutical Research, Vol. 27, No. 1, 2010, p. 143-150.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Role of in vitro release models in formulation development and quality control of parenteral depots. / Larsen, Claus; Larsen, Susan Weng; Yaghmur, Anan; Ostergaard, Jesper; Jensen, Henrik.
In: Expert Opinion on Drug Delivery, Vol. 6, No. 12, 12.2009, p. 1283-1295.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of low-molecular-weight cationic ligands to chondroitin sulfate as studied by capillary electrophoresis frontal analysis. / Østergaard, Jesper; Jensen, Henrik; Larsen, Susan Weng; Larsen, Claus Richard; Larsen, Claus Selch.
In: Open Analytical Chemistry Journal, Vol. 3, 2009, p. 16-21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Critical factors influencing the In Vivo performance of long-acting liophilic solutions - impact on In Vitro release method design. / Larsen, Susan Weng; Larsen, Claus Selch.
In: The AAPS Journal, Vol. 11, No. 4, 2009, p. 762-770.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of in vitro release models in formulation development and quality control of parenteral depots. / Larsen, Claus Selch; Larsen, Susan Weng; Jensen, Henrik; Yaghmur, Anan; Østergaard, Jesper.
In: Expert Opinion on Drug Delivery, Vol. 6, No. 12, 2009, p. 1283-1295.Research output: Contribution to journal › Review › Research
- 2008
- Published
Assessment of drug release from oil depot formulations using an in vitro model : Potential applicability in accelerated release testing. / Larsen, Susan Weng; Jessen, Marit N. B.; Østergaard, Jesper; Larsen, Claus Selch.
In: Drug Development and Industrial Pharmacy, Vol. 34, No. 3, 2008, p. 297-304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis. / Østergaard, Jesper; Jørgensen, Lene; Thomsen, Anne Engelbrecht; Larsen, Susan Weng; Larsen, Claus Selch; Jensen, Henrik.
In: Electrophoresis, Vol. 29, No. 16, 2008, p. 3320 - 3324.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro assessment of lidocaine release from aqueous and oil solutions and from preformed and in situ formed aqueos and oil suspensions. Parenteral depots for intra-articular administration. / Pedersen, Brian Thoning; Larsen, Susan Weng; Østergaard, Jesper; Larsen, Claus Selch.
In: Drug Delivery, Vol. 15, No. 1, 2008, p. 23-30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intra-articular depot formulation principles : role in the management of postoperative pain and arthritic disorders. / Larsen, Claus Selch; Østergaard, Jesper; Larsen, Susan Weng; Jensen, Henrik; Jacobsen, Stine; Lindegaard, Casper; Andersen, Pia Haubro.
In: Journal of Pharmaceutical Sciences, Vol. 97, No. 11, 2008, p. 4622-4654.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds. / Larsen, Susan Weng; Frost, Anna Buus; Østergaard, Jesper; Marcher, Hermann; Larsen, Claus Selch.
In: European Journal of Pharmaceutical Sciences, Vol. 34, No. 1, 2008, p. 37-44.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model. / Larsen, Susan Weng; Østergaard, Jesper; Poulsen, Sara; Schulz, Bjørn; Larsen, Claus Selch.
In: European Journal of Pharmaceutical Sciences, Vol. 31, No. 3-4, 2007, p. 172-179.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1304281
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Basic characteristics and kinetics of degradation in aqueous buffer of selected diclofenac prodrugs intended for joint injection
Research output: Contribution to conference › Poster › Research › peer-review
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