Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2017
  2. Published

    Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels. / Mahendran, Yuvaraj; Jonsson, Anna; Have, Christian T; Allin, Kristine H; Witte, Daniel R; Jørgensen, Marit E; Grarup, Niels; Pedersen, Oluf; Kilpeläinen, Tuomas O; Hansen, Torben.

    In: Diabetologia, Vol. 60, No. 5, 10.02.2017, p. 873-878.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Rare and low-frequency coding variants alter human adult height. / Marouli, Eirini; Graff, Mariaelisa; Medina-Gomez, Carolina; Lo, Ken Sin; Wood, Andrew R; Kjaer, Troels R; Fine, Rebecca S; Lu, Yingchang; Schurmann, Claudia; Highland, Heather M; Rüeger, Sina; Thorleifsson, Gudmar; Justice, Anne E; Lamparter, David; Stirrups, Kathleen E; Turcot, Valérie; Young, Kristin L; Winkler, Thomas W; Esko, Tõnu; Karaderi, Tugce; Locke, Adam E; Masca, Nicholas G D; Ng, Maggie C Y; Mudgal, Poorva; Rivas, Manuel A; Vedantam, Sailaja; Mahajan, Anubha; Guo, Xiuqing; Abecasis, Goncalo; Aben, Katja K; Allin, Kristine H; Appel, Emil V.; Bang, Lia E; Benn, Marianne; Bork-Jensen, Jette; Frikke-Schmidt, Ruth; Grarup, Niels; Hansen, Torben; Hollensted, Mette; Jensen, Gorm B; Jørgensen, Marit E; Jørgensen, Torben; Kamstrup, Pia R; Linneberg, Allan; Nielsen, Sune F; Nordestgaard, Børge G; Pedersen, Oluf; Tybjaerg-Hansen, Anne; Vestergaard, Henrik; Pers, Tune H; EPIC-InterAct Consortium.

    In: Nature, Vol. 542, No. 7640, 09.02.2017, p. 186-190.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    PCSK9 genetic variants and risk of type 2 diabetes : a mendelian randomisation study. / Schmidt, Amand F; Swerdlow, Daniel I; Holmes, Michael V; Patel, Riyaz S; Fairhurst-Hunter, Zammy; Lyall, Donald M; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hyppönen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, G Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; Demuth, Juri; Bertram, Lars; Liu, Tian; Coassin, Stefan; Willeit, Johann; Kiechl, Stefan; Willeit, Karin; Mason, Dan; Wright, John; Morris, Richard; Wanamethee, Goya; Whincup, Peter; Ben-Shlomo, Yoav; McLachlan, Stela; Price, Jackie F; Kivimaki, Mika; Welch, Catherine; Sanchez-Galvez, Adelaida; Marques-Vidal, Pedro; Nicolaides, Andrew; Panayiotou, Andrie G; Onland-Moret, N Charlotte; van der Schouw, Yvonne T; Matullo, Giuseppe; Fiorito, Giovanni; Guarrera, Simonetta; Sacerdote, Carlotta; Wareham, Nicholas J; Langenberg, Claudia; Scott, Robert; Grarup, Niels; Pedersen, Oluf; Hansen, Torben; Linneberg, Allan; LifeLines Cohort study group.

    In: The Lancet Diabetes & Endocrinology, Vol. 5, No. 2, 02.2017, p. 97–105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Cohort description : The Danish study of Functional Disorders. / Dantoft, Thomas Meinertz; Ebstrup, Jeanette Frost; Linneberg, Allan; Skovbjerg, Sine; Madsen, Anja Lykke; Mehlsen, Jesper; Brinth, Louise; Eplov, Lene Falgaard; Carstensen, Tina Wisbech; Schroder, Andreas; Fink, Per Klausen; Mortensen, Erik Lykke; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben.

    In: Clinical Epidemiology, Vol. 9, 02.2017, p. 127-139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genetic determinants of serum vitamin B12 and their relation to body mass index. / Allin, Kristine H; Friedrich, Nele; Pietzner, Maik; Grarup, Niels; Thuesen, Betina H; Linneberg, Allan; Pisinger, Charlotta; Hansen, Torben; Pedersen, Oluf; Sandholt, Camilla H.

    In: European Journal of Epidemiology, Vol. 32, No. 2, 02.2017, p. 125–134.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. / Wood, Andrew R; Jonsson, Anna; Jackson, Anne U; Wang, Tian-Nan; van Leewen, Nienke; Palmer, Nicholette D; Kobes, Sayuko; Deelen, Joris; Boquete-Vilarino, Lorena; Paananen, Jussi; Stančáková, Alena; Boomsma, Dorret I; de Geus, Eco Jc; Eekhoff, Elisabeth Mw; Fritsche, Andreas; Kramer, Mark; Nijpels, Giel; Simonis-Bik, Annemarie M C; van Haeften, Timon W; Mahajan, Anubha; Boehnke, Michael; Bergman, Richard N; Tuomilehto, Jaakko; Collins, Francis S; Mohlke, Karen L; Banasik, Karina; Groves, Christopher J; McCarthy, Mark I; Pearson, Ewan R; Natali, Andrea; Mari, Andrea; Buchanan, Thomas A; Taylor, Kent D; Xiang, Anny H; Gjesing, Anette P; Grarup, Niels; Eiberg, Hans; Pedersen, Oluf; Chen, Yii-Derr; Laakso, Markku; Norris, Jill M; Smith, Ulf; Wagenknecht, Lynne E; Baier, Leslie; Bowden, Donald W; Hansen, Torben; Walker, Mark; Watanabe, Richard M; 't Hart, Leen M; Hanson, Robert L; Frayling, Timothy M.

    In: Diabetes, Vol. 66, No. 8, 2017, p. 2296-2309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents. / Nielsen, Tenna Ruest Haarmark; Appel, Emil Vincent Rosenbaum; Svendstrup, Mathilde; Ohrt, Johanne Dam; Dahl, Maria; Fonvig, Cilius Esmann; Hollensted, Mette; Have, Christian Theil; Kadarmideen, Haja N; Pedersen, Oluf; Hansen, Torben; Holm, Jens-Christian; Grarup, Niels.

    In: PloS one, Vol. 12, No. 3, e0174204, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. / Scott, Robert A; Scott, Laura J; Mägi, Reedik; Marullo, Letizia; Gaulton, Kyle J; Kaakinen, Marika; Pervjakova, Natalia; Pers, Tune H; Johnson, Andrew D; Eicher, John D; Jackson, Anne U; Ferreira, Teresa; Lee, Yeji; Ma, Clement; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Van Zuydam, Natalie R; Mahajan, Anubha; Chen, Han; Almgren, Peter; Voight, Ben F; Grallert, Harald; Müller-Nurasyid, Martina; Ried, Janina S; Rayner, William N; Robertson, Neil; Karssen, Lennart C; van Leeuwen, Elisabeth M; Willems, Sara M; Fuchsberger, Christian; Kwan, Phoenix; Teslovich, Tanya M; Chanda, Pritam; Li, Man; Lu, Yingchang; Dina, Christian; Thuillier, Dorothee; Yengo, Loic; Jiang, Longda; Sparso, Thomas; Kestler, Hans A; Chheda, Himanshu; Eisele, Lewin; Gustafsson, Stefan; Frånberg, Mattias; Strawbridge, Rona J; Benediktsson, Rafn; Hreidarsson, Astradur B; Kong, Augustine; Sigurðsson, Gunnar; Kerrison, Nicola D; Luan, Jian'an; Liang, Liming; Meitinger, Thomas; Roden, Michael; Thorand, Barbara; Esko, Tõnu; Mihailov, Evelin; Fox, Caroline; Liu, Ching-Ti; Rybin, Denis; Isomaa, Bo; Lyssenko, Valeriya; Tuomi, Tiinamaija; Couper, David J; Pankow, James S; Grarup, Niels; Have, Christian T; Jørgensen, Marit E; Jørgensen, Torben; Linneberg, Allan; Cornelis, Marilyn C; van Dam, Rob M; Hunter, David J; Kraft, Peter; Sun, Qi; Edkins, Sarah; Owen, Katharine R; Perry, John Rb; Wood, Andrew R; Zeggini, Eleftheria; Tajes-Fernandes, Juan; Abecasis, Goncalo R; Bonnycastle, Lori L; Chines, Peter S; Stringham, Heather M; Koistinen, Heikki A; Kinnunen, Leena; Sennblad, Bengt; Mühleisen, Thomas W; Nöthen, Markus M; Pechlivanis, Sonali; Baldassarre, Damiano; Gertow, Karl; Humphries, Steve E; Tremoli, Elena; Klopp, Norman; Meyer, Julia; Steinbach, Gerald; Wennauer, Roman; Eriksson, Johan G; Mӓnnistö, Satu; Peltonen, Leena; Tikkanen, Emmi; Charpentier, Guillaume; Eury, Elodie; Lobbens, Stéphane; Gigante, Bruna; Leander, Karin; McLeod, Olga; Bottinger, Erwin P; Gottesman, Omri; Ruderfer, Douglas; Blüher, Matthias; Kovacs, Peter; Tonjes, Anke; Maruthur, Nisa M; Scapoli, Chiara; Erbel, Raimund; Jöckel, Karl-Heinz; Moebus, Susanne; de Faire, Ulf; Hamsten, Anders; Stumvoll, Michael; Deloukas, Panagiotis; Donnelly, Peter J; Frayling, Timothy M; Hattersley, Andrew T; Ripatti, Samuli; Salomaa, Veikko; Pedersen, Nancy L; Boehm, Bernhard O; Bergman, Richard N; Collins, Francis S; Mohlke, Karen L; Tuomilehto, Jaakko; Hansen, Torben; Pedersen, Oluf; Barroso, Inês; Lannfelt, Lars; Ingelsson, Erik; Lind, Lars; Lindgren, Cecilia M; Cauchi, Stephane; Froguel, Philippe; Loos, Ruth Jf; Balkau, Beverley; Boeing, Heiner; Franks, Paul W; Gurrea, Aurelio Barricarte; Palli, Domenico; van der Schouw, Yvonne T; Altshuler, David; Groop, Leif C; Langenberg, Claudia; Wareham, Nicholas J; Sijbrands, Eric; van Duijn, Cornelia M; Florez, Jose C; Meigs, James B; Boerwinkle, Eric; Gieger, Christian; Strauch, Konstantin; Metspalu, Andres; Morris, Andrew D; Palmer, Colin Na; Hu, Frank B; Thorsteinsdottir, Unnur; Stefansson, Kari; Dupuis, Josée; Morris, Andrew P; Boehnke, Michael; McCarthy, Mark I; Prokopenko, Inga.

    In: Diabetes, Vol. 66, No. 11, 2017, p. 2888-2902.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion. / Danish Pan Genome Consortium; Sørensen, Lasse Maretty; Petersen, Bent; Sibbesen, Jonas Andreas; Liu, Siyang; Belling, Kirstine G; Have, Christian Theil; Bork-Jensen, Jette; Hansen, Torben; Krogh, Anders; Sørensen, Thorkild I.A.; Pedersen, Oluf Borbye; Rasmussen, Simon; Kristiansen, Karsten; Brunak, Søren.

    In: PLOS Genetics, Vol. 13, No. 8, 2017, p. e1006834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies. / Møllehave, L T; Skaaby, T; Simonsen, K S; Thuesen, B H; Mortensen, Erik Lykke; Sandholt, C H; Pedersen, O; Grarup, N; Hansen, T; Linneberg, A.

    In: European Journal of Clinical Nutrition, Vol. 71, 2017, p. 1054-1060.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Causal relationship between obesity and serum testosterone status in men : A bi-directional mendelian randomization analysis. / Eriksson, Joel; Haring, Robin; Grarup, Niels; Vandenput, Liesbeth; Wallaschofski, Henri; Lorentzen, Erik; Hansen, Torben; Mellström, Dan; Pedersen, Oluf; Nauck, Matthias; Lorentzon, Mattias; Nystrup Husemoen, Lise Lotte; Völzke, Henry; Karlsson, Magnus; Baumeister, Sebastian E; Linneberg, Allan; Ohlsson, Claes.

    In: PloS one, Vol. 12, No. 4, e0176277, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Dairy consumption, systolic blood pressure, and risk of hypertension : Mendelian randomization study. / Ding, Ming; Huang, Tao; Bergholdt, Helle K M; Sørensen, Thorkild I.A.; Linneberg, Allan René; Sandholt, Camilla Helene; Pedersen, Oluf ; Hansen, Torben; Kilpeläinen, Tuomas O; CHARGE Consortium ; Nordestgaard, Børge G; Ellervik, Christina; Qi, Lu; Mendelian Randomization of Dairy Consumption Working Group.

    In: The BMJ, Vol. 356, j1000, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Estimates of insulin sensitivity and β-cell function in children and adolescents with and without components of the metabolic syndrome. / Frithioff-Bøjsøe, Christine; Trier, Cæcilie; Esmann Fonvig, Cilius; Nissen, Anne; Kloppenborg, Julie Tonsgaard; Mollerup, Pernille Maria; Bjerrum, Poul Jannik; Pedersen, Oluf; Hansen, Torben; Holm, Jens-Christian.

    In: Pediatric Endocrinology, Diabetes and Metabolism, Vol. 23, No. 3, 2017, p. 122-129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans. / Søberg, Susanna; Sandholt, Camilla Helene; Z. Jespersen, Naja ; Toft, Ulla; L. Madsen, Anja ; von Holstein-Rathlou, Stephanie Ø; Grevengoed, Trisha Jean; Christensen, Karl Bang; Bredie, Wender; Potthoff, Matthew J; P. J. Solomon, Thomas; Schéele, Camilla Charlotte; Linneberg, Allan René; Jørgensen, Torben; Pedersen, Oluf Borbye; Hansen, Torben; Gillum, Matthew Paul; Grarup, Niels.

    In: Cell Metabolism, Vol. 25, No. 5, 2017, p. 1045-1053.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function. / Jorgensen, Stine; Have, Christian Theil; Underwood, Christina Rye; Johansen, Lars Dan; Wellendorph, Petrine; Gjesing, Anette Prior; Jorgensen, Christinna V.; Quan, Shi; Rui, Gao; Inoue, Asuka; Linneberg, Allan; Grarup, Niels; Jun, Wang; Pedersen, Oluf; Hansen, Torben; Bräuner-Osborne, Hans.

    In: The Journal of Biological Chemistry, Vol. 292, No. 4, 2017, p. 1524-1534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk. / Hulman, Adam; Simmons, Rebecca Kate; Vistisen, Dorte; Tabák, Adam G; Dekker, Jacqueline M; Alssema, Marjan; Rutters, Femke; Koopman, Anitra D M; Solomon, Thomas P J; Kirwan, John P; Hansen, Torben; Jonsson, Anna Elisabet; Gjesing, Anette Marianne Prior; Eiberg, Hans Rudolf Lytchoff; Astrup, Arne; Pedersen, Oluf Borbye; Sørensen, Thorkild I.A.; Witte, Daniel; Færch, Kristine.

    In: Endocrine, Vol. 55, No. 2, 2017, p. 427-434.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus. / Gjesing, Anette Marianne Prior; Rui, Gao; Lauenborg, Jeannet; Have, Christian Theil; Hollensted, Mette; Andersson, Ehm ; Grarup, Niels; Sun, Jihua; Quan, Shi; Brandslund, Ivan; Damm, Peter; Pedersen, Oluf; Wang, Jun; Hansen, Torben.

    In: Endocrine Research, Vol. 1, No. 6, 2017, p. 681-690.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Higher intake of fish and fat is associated with lower plasma s-adenosylhomocysteine : a cross-sectional study. / Lind, Mads Vendelbo; Lauritzen, Lotte; Pedersen, Oluf Borbye; Vestergaard, Henrik; Stark, Ken D; Hansen, Torben; Ross, Alastair B.; Kristensen, Mette Bredal.

    In: Nutrition Research, Vol. 46, 2017, p. 78-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Investigating the causal effect of smoking on hay fever and asthma : a Mendelian randomization meta-analysis in the CARTA consortium. / Skaaby, Tea; Taylor, Amy E; Jacobsen, Rikke K; Paternoster, Lavinia; Thuesen, Betina H; Ahluwalia, Tarunveer S; Larsen, Sofus C; Zhou, Ang; Wong, Andrew; Gabrielsen, Maiken E; Bjørngaard, Johan H; Flexeder, Claudia; Männistö, Satu; Hardy, Rebecca; Kuh, Diana; Barry, Sarah J; Tang Møllehave, Line; Cerqueira, Charlotte; Friedrich, Nele; Bonten, Tobias N; Noordam, Raymond; Mook-Kanamori, Dennis O; Taube, Christian; Jessen, Leon E; McConnachie, Alex; Sattar, Naveed; Upton, Mark N; McSharry, Charles; Bønnelykke, Klaus; Bisgaard, Hans; Schulz, Holger; Strauch, Konstantin; Meitinger, Thomas; Peters, Annette; Grallert, Harald; Nohr, Ellen A; Kivimaki, Mika; Kumari, Meena; Völker, Uwe; Nauck, Matthias; Völzke, Henry; Power, Chris; Hyppönen, Elina; Hansen, Torben; Jørgensen, Torben; Pedersen, Oluf; Salomaa, Veikko; Grarup, Niels; Langhammer, Arnulf; Romundstad, Pål R; Skorpen, Frank; Kaprio, Jaakko; R Munafò, Marcus; Linneberg, Allan.

    In: Scientific Reports, Vol. 7, No. 1, 2224, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Predicting glycated hemoglobin levels in the non-diabetic general population : Development and validation of the DIRECT-DETECT prediction model - a DIRECT study. / Rauh, Simone P; Heymans, Martijn W; Koopman, Anitra D M; Nijpels, Giel; Stehouwer, Coen D; Thorand, Barbara; Rathmann, Wolfgang; Meisinger, Christa; Peters, Annette; de Las Heras Gala, Tonia; Glümer, C; Pedersen, Oluf; Cederberg, Henna; Kuusisto, Johanna; Laakso, Markku; Pearson, Ewan R; Franks, Paul W; Rutters, Femke; Dekker, Jacqueline M.

    In: PLOS ONE, Vol. 12, No. 2, e0171816, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. / Li, Man; Li, Yong; Weeks, Olivia; Mijatovic, Vladan; Teumer, Alexander; Huffman, Jennifer E; Tromp, Gerard; Fuchsberger, Christian; Gorski, Mathias; Lyytikäinen, Leo-Pekka; Nutile, Teresa; Sedaghat, Sanaz; Sorice, Rossella; Tin, Adrienne; Yang, Qiong; Ahluwalia, Tarunveer S; Arking, Dan E; Bihlmeyer, Nathan A; Böger, Carsten A; Carroll, Robert J; Chasman, Daniel I; Cornelis, Marilyn C; Dehghan, Abbas; Faul, Jessica D; Feitosa, Mary F; Gambaro, Giovanni; Gasparini, Paolo; Giulianini, Franco; Heid, Iris; Huang, Jinyan; Imboden, Medea; Jackson, Anne U; Jeff, Janina; Jhun, Min A; Katz, Ronit; Kifley, Annette; Kilpeläinen, Tuomas O; Kumar, Ashish; Laakso, Markku; Li-Gao, Ruifang; Lohman, Kurt; Lu, Yingchang; Mägi, Reedik; Bork-Jensen, Jette; Glümer, Charlotte; Grarup, Niels; Husemoen, Lise Lotte N; Jørgensen, Torben; Linneberg, Allan; Pedersen, Oluf; CHARGE Glycemic-T2D Working Group,.

    In: Journal of the American Society of Nephrology, Vol. 28, No. 3, 2017, p. 981-994.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The effect of metformin on a healthy human gut microbiota. / Nielsen, T.; Bryrup, T.; Thomsen, C.W.; Hansen, T. H.; Kern, T.; Allin, K. H.; Jørgensen, N.R.; Vestergaard, H.; Hansen, T.; Pedersen, O.

    In: Diabetologia, Vol. 60, No. Suppl. 1, 241, 2017, p. S113.

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes. / Sørensen, Anne-Sofie; Kjær, Laura Kofoed; Petersen, Kasper Meidahl; Henriksen, Trine; Cejvanovic, Vanja; Pedersen, Oluf; Hansen, Torben; Christensen, Cramer Kjeldahl; Brandslund, Ivan; Poulsen, Henrik Enghusen.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 77, No. 4, 2017, p. 253-258.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts. / Friedrich, Nele; Pietzner, Maik; Cannet, Claire; Thuesen, Betina H; Hansen, Torben; Wallaschofski, Henri; Grarup, Niels; Skaaby, Tea; Budde, Kathrin; Pedersen, Oluf; Nauck, Matthias; Linneberg, Allan.

    In: PLOS ONE, Vol. 12, No. 3, e0173078, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 919113