Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects : validation and extension of genome-wide association studies. / Grarup, Niels; Rose, Chrisian S; Andersson, Ehm A; Andersen, Gitte; Nielsen, Arne L; Albrechtsen, Anders; Clausen, Jesper O; Rasmussen, Signe S; Jørgensen, Torben; Sandbaek, Annelli; Lauritzen, Torsten; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 56, No. 12, 2007, p. 3105-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects. / Grarup, Niels; Stender-Petersen, Kirstine L; Andersson, Ehm A; Jørgensen, Torben; Borch-Johnsen, Knut; Sandbæk, Annelli; Lauritzen, Torsten; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 57, No. 4, 2008, p. 1136-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects. / Grarup, Niels; Andreasen, Camilla H; Andersen, Mette K; Albrechtsen, Anders; Sandbaek, Annelli; Lauritzen, Torsten; Borch-Johnsen, Knut; Jørgensen, Torben; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 6, 2008, p. 2294-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population. / Grarup, Niels; Moltke, Ida; Andersen, Mette K.; Bjerregaard, Peter; Larsen, Christina V.L.; Dahl-Petersen, Inger K.; Jørsboe, Emil; Tiwari, Hemant K.; Hopkins, Scarlett E.; Wiener, Howard W.; Boyer, Bert B.; Linneberg, Allan; Pedersen, Oluf; Jørgensen, Marit E.; Albrechtsen, Anders; Hansen, Torben.

    In: Diabetologia, Vol. 61, No. 9, 09.2018, p. 2005–2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet. / Grau, Katrine; Cauchi, Stephane; Holst, Claus; Astrup, Arne; Martinez, J. Alfredo; Saris, Wim H.M.; Blaak, Ellen E; Oppert, Jean-Michel; Arner, Peter; Rössner, Stephan; Macdonald, Ian A.; Klimcakova, Eva; Langin, Dominique; Pedersen, Oluf; Froguel, Philippe; Sørensen, Thorkild I.A.

    In: American Journal of Clinical Nutrition, Vol. 91, No. 2, 2010, p. 472-479.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease. / Gretarsdottir, Solveig; Helgason, Hannes; Helgadottir, Anna; Sigurdsson, Asgeir; Thorleifsson, Gudmar; Magnusdottir, Audur; Oddsson, Asmundur; Steinthorsdottir, Valgerdur; Rafnar, Thorunn; de Graaf, Jacqueline; Daneshpour, Maryam S; Hedayati, Mehdi; Azizi, Fereidoun; Grarup, Niels; Jørgensen, Torben; Vestergaard, Henrik; Hansen, Torben; Eyjolfsson, Gudmundur; Sigurdardottir, Olof; Olafsson, Isleifur; Kiemeney, Lambertus A; Pedersen, Oluf; Sulem, Patrick; Thorgeirsson, Gudmundur; Gudbjartsson, Daniel F; Holm, Hilma; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: P L o S Genetics, Vol. 11, No. 9, e1005379, 09.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. / Gretarsdottir, Solveig; Baas, Annette F; Thorleifsson, Gudmar; Holm, Hilma; den Heijer, Martin; de Vries, Jean-Paul P M; Kranendonk, Steef E; Zeebregts, Clark J A M; van Sterkenburg, Steven M; Geelkerken, Robert H; van Rij, Andre M; Williams, Michael J A; Boll, Albert P M; Kostic, Jelena P; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Walters, G Bragi; Masson, Gisli; Sulem, Patrick; Saemundsdottir, Jona; Mouy, Magali; Magnusson, Kristinn P; Tromp, Gerard; Elmore, James R; Sakalihasan, Natzi; Limet, Raymond; Defraigne, Jean-Olivier; Ferrell, Robert E; Ronkainen, Antti; Ruigrok, Ynte M; Wijmenga, Cisca; Grobbee, Diederick E; Shah, Svati H; Granger, Christopher B; Quyyumi, Arshed A; Vaccarino, Viola; Patel, Riyaz S; Zafari, A Maziar; Levey, Allan I; Austin, Harland; Girelli, Domenico; Pignatti, Pier Franco; Olivieri, Oliviero; Martinelli, Nicola; Malerba, Giovanni; Trabetti, Elisabetta; Becker, Lewis C; Becker, Diane M; Reilly, Muredach P; Rader, Daniel J; Mueller, Thomas; Dieplinger, Benjamin; Haltmayer, Meinhard; Urbonavicius, Sigitas; Lindblad, Bengt; Gottsäter, Anders; Gaetani, Eleonora; Pola, Roberto; Wells, Philip; Rodger, Marc; Forgie, Melissa; Langlois, Nicole; Corral, Javier; Vasquez, Vicente; Fontcuberta, Jordi; España, Francisco; Grarup, Niels; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; Aben, Katja K; de Graaf, Jacqueline; Holewijn, Suzanne; Folkersen, Lasse; Franco-Cereceda, Anders; Eriksson, Per; Collier, David A; Stefansson, Hreinn; Steinthorsdottir, Valgerdur; Rafnar, Thorunn; Valdimarsson, Einar M; Magnadottir, Hulda B; Sveinbjornsdottir, Sigurlaug; Olafsson, Isleifur; Magnusson, Magnus Karl; Palmason, Robert; Haraldsdottir, Vilhelmina; Andersen, Karl; Onundarson, Pall T; Thorgeirsson, Gudmundur; Kiemeney, Lambertus A; Powell, Janet T; Carey, David J; Kuivaniemi, Helena; Lindholt, Jes S.; Jones, Gregory T; Kong, Augustine; Blankensteijn, Jan D; Matthiasson, Stefan E; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 42, No. 8, 01.08.2010, p. 692-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue. / Grunnet, Louise G; Nilsson, Emma; Ling, Charlotte; Hansen, Torben; Pedersen, Oluf; Groop, Leif; Vaag, Allan; Poulsen, Pernille.

    In: Diabetes, 2009, p. 2402-2408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609. / Grunnet, Louise Groth; Brøns, Charlotte; Jacobsen, Stine; Nilsson, Emma; Astrup, Arne; Hansen, Torben; Pedersen, Oluf; Poulsen, Pernille; Quistorff, Bjørn; Vaag, Allan.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2009, p. 596-602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Increased recovery rates of phosphocreatine (PCr) and inorganic phosphate (Pi) after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in carriers of the fat mass and obesity-associated FTO genotypes. / Grunnet, Louise Groth; Brøns, Charlotte; Jacobsen, Stine; Nielsen, Emma; Astrup, Arne; Hansen, Torben; Pedersen, Oluf; Poulsen, Pernille; Quistorff, Bjørn; Vaag, Allan.

    In: Diabetes, Vol. 57, No. Suppl. 1, 2008, p. A329.

    Research output: Contribution to journalConference abstract in journalResearch

  11. Published

    Many sequence variants affecting diversity of adult human height. / Gudbjartsson, Daniel F; Walters, G Bragi; Thorleifsson, Gudmar; Stefansson, Hreinn; Halldorsson, Bjarni V; Zusmanovich, Pasha; Sulem, Patrick; Thorlacius, Steinunn; Gylfason, Arnaldur; Steinberg, Stacy; Helgadottir, Anna; Ingason, Andres; Steinthorsdottir, Valgerdur; Olafsdottir, Elinborg J; Olafsdottir, Gudridur H; Jonsson, Thorvaldur; Borch-Johnsen, Knut; Hansen, Torben; Andersen, Gitte; Jørgensen, Torben; Pedersen, Oluf; Aben, Katja K; Witjes, J Alfred; Swinkels, Dorine W; den Heijer, Martin; Franke, Barbara; Verbeek, Andre L M; Becker, Diane M; Yanek, Lisa R; Becker, Lewis C; Tryggvadottir, Laufey; Rafnar, Thorunn; Gulcher, Jeffrey; Kiemeney, Lambertus A; Kong, Augustine; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 40, No. 5, 2008, p. 609-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. / Gudmundsson, Julius; Sulem, Patrick; Steinthorsdottir, Valgerdur; Bergthorsson, Jon T; Thorleifsson, Gudmar; Manolescu, Andrei; Rafnar, Thorunn; Gudbjartsson, Daniel; Agnarsson, Bjarni A; Baker, Adam; Sigurdsson, Asgeir; Benediktsdottir, Kristrun R; Jakobsdottir, Margret; Blondal, Thorarinn; Stacey, Simon N; Helgason, Agnar; Gunnarsdottir, Steinunn; Olafsdottir, Adalheidur; Kristinsson, Kari T; Birgisdottir, Birgitta; Ghosh, Shyamali; Thorlacius, Steinunn; Magnusdottir, Dana; Stefansdottir, Gerdur; Kristjansson, Kristleifur; Bagger, Yu; Wilensky, Robert L; Reilly, Muredach P; Morris, Andrew D; Kimber, Charlotte H; Adeyemo, Adebowale; Chen, Yuanxiu; Zhou, Jie; So, Wing-Yee; Tong, Peter C Y; Ng, Maggie C Y; Hansen, Torben; Andersen, Gitte; Borch-Johnsen, Knut; Jorgensen, Torben; Tres, Alejandro; Fuertes, Fernando; Ruiz-Echarri, Manuel; Asin, Laura; Saez, Berta; van Boven, Erica; Klaver, Siem; Swinkels, Dorine W; Aben, Katja K; Graif, Theresa; Cashy, John; Suarez, Brian K; van Vierssen Trip, Onco; Frigge, Michael L; Ober, Carole; Hofker, Marten H; Wijmenga, Cisca; Christiansen, Claus; Rader, Daniel J; Palmer, Colin N A; Rotimi, Charles; Chan, Juliana C N; Pedersen, Oluf; Sigurdsson, Gunnar; Benediktsson, Rafn; Jonsson, Eirikur; Einarsson, Gudmundur V; Mayordomo, Jose I; Catalona, William J; Kiemeney, Lambertus A; Barkardottir, Rosa B; Gulcher, Jeffrey R; Thorsteinsdottir, Unnur; Kong, Augustine; Stefansson, Kari.

    In: Nature Genetics, Vol. 39, No. 8, 2007, p. 977-983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility. / Guigas, B; de Leeuw van Weenen, J E; van Leeuwen, N; Simonis-Bik, A M; van Haeften, T W; Nijpels, G; Houwing-Duistermaat, J J; Beekman, M; Deelen, J; Havekes, L M; Penninx, B W J H; Vogelzangs, N; van 't Riet, E; Dehghan, A; Hofman, A; Witteman, J C; Uitterlinden, A G; Grarup, Niels; Jørgensen, Torben; Witte, D R; Lauritzen, T; Hansen, Torben; Pedersen, O; Hottenga, J; Romijn, J A; Diamant, M; Kramer, M H H; Heine, R J; Willemsen, G; Dekker, J M; Eekhoff, E M; Pijl, H; de Geus, E J; Slagboom, P E; 't Hart, L M.

    In: Diabetic Medicine, Vol. 31, No. 8, 08.2014, p. 1001-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C. / Gutiérrez-Aguilar, Ruth; Froguel, Philippe; Hamid, Yasmin H; Benmezroua, Yamina; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, Torben; Pedersen, Oluf; Neve, Bernadette.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 8, 2008, p. 3128-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Functional SOCS1 polymorphisms are associated with variation in obesity in whites. / Gylvin, T; Ek, J; Nolsøe, R.; Albrechtsen, A.; Andersen, G; Bergholdt, R.; Brorsson, C; Bang-Berthelsen, C. H.; Hansen, T.; Karlsen, A. E.; Billestrup, N; Borch-Johnsen, K; Jørgensen, Torben; Pedersen, Oluf; Mandrup-Poulsen, T; Nerup, J.; Pociot, Flemming Michael.

    In: Diabetes, Obesity and Metabolism, Vol. 11, No. 3, 2009, p. 196-203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A cost analysis of intensified vs conventional multifactorial therapy in individuals with type 2 diabetes : a post hoc analysis of the Steno-2 study. / Gæde, Joachim; Oellgaard, Jens; Ibsen, Rikke; Gæde, Peter; Nortoft, Emil; Parving, Hans-Henrik; Kjellberg, Jakob; Pedersen, Oluf.

    In: Diabetologia, Vol. 62, No. 1, 2019, p. 147-155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences. / Gæde, Joachim; Nielsen, Trine; Madsen, Mia L; Toft, Ulla; Jørgensen, Torben; Overvad, Kim; Tjønneland, Anne; Hansen, Torben; Allin, Kristine H; Pedersen, Oluf.

    In: Nutrition Journal, Vol. 17, No. 1, 91, 06.10.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria : 21 years follow-up on the Steno-2 randomised trial. / Gæde, Peter; Øllgaard, Jens Christian; Carstensen, Bendix; Rossing, Peter; Lund-Andersen, Henrik; Parving, Hans-Henrik; Pedersen, Oluf.

    In: Diabetologia, Vol. 59, No. 11, 11.2016, p. 2298-2307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Beneficial impact of intensified multifactorial intervention on risk of stroke: outcome of 21 years of follow-up in the randomised Steno-2 Study. / Gæde, Peter; Oellgaard, Jens; Kruuse, Christina; Rossing, Peter; Parving, Hans-Henrik; Pedersen, Oluf.

    In: Diabetologia, Vol. 62, No. 9, 2019, p. 1575-1580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Association between neuromedin U gene variants and overweight and obesity. / Hainerová, Irena; Torekov, Signe S; Ek, Jakob; Finková, Marie; Borch-Johnsen, Knut; Jørgensen, Torben; Madsen, Ole D; Lebl, Jan; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 91, No. 12, 2006, p. 5057-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Melanocortin 4 receptor mutations in obese Czech children : studies of prevalence, phenotype development, weight reduction response, and functional analysis. / Hainerová, Irena; Larsen, Lesli H; Holst, Birgitte; Finková, Marie; Hainer, Vojtech; Lebl, Jan; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 92, No. 9, 2007, p. 3689-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites. / Hamid, Yasmin H; Urhammer, Søren A; Jensen, Dorit P; Glümer, Charlotte; Borch-Johnsen, Knut; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 53, No. 12, 2004, p. 3342-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM. / Hansen, L; Arden, K C; Rasmussen, S B; Viars, C S; Vestergaard, H; Hansen, T; Møller, A M; Woodgett, J R; Pedersen, O.

    In: Diabetologia, Vol. 40, No. 8, 08.1997, p. 940-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus. / Hansen, L; Jensen, J N; Ekstrøm, C T; Vestergaard, H; Hansen, T; Pedersen, O; Vestergaard, Henrik.

    In: Diabetologia, Vol. 44, No. 2, 02.2001, p. 237-240.

    Research output: Contribution to journalJournal articleResearchpeer-review

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