Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes. / Sparsø, T; Andersen, G; Nielsen, T; Burgdorf, K S; Gjesing, Anette Marianne Prior; Nielsen, A L; Albrechtsen, Anders; Rasmussen, S S; Jørgensen, Torben; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Madsbad, S; Hansen, T; Pedersen, Oluf.

    In: Diabetologia, Vol. 51, No. 1, 2007, p. 70-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation. / Sparsø, T; Andersen, G; Albrechtsen, Anders; Jørgensen, T; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Wasson, J; Permutt, M A; Glaser, B; Madsbad, S; Pedersen, Oluf; Hansen, T.

    In: Diabetologia, Vol. 51, No. 9, 2008, p. 1646-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes (Diabetologia DOI : 10.1007/s00125-007-0865-z). / Sparsø, T.; Andersen, G.; Nielsen, T.; Burgdorf, K. S.; Gjesing, A. P.; Nielsen, A. L.; Albrechtsen, A.; Rasmussen, S. S.; Jørgensen, T.; Borch-Johnsen, K.; Sandbæk, A.; Lauritzen, T.; Madsbad, S.; Hansen, T.; Pedersen, O.

    In: Diabetologia, Vol. 51, No. 2, 01.02.2008.

    Research output: Contribution to journalComment/debateResearchpeer-review

  4. Published

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans. / Sparsø, Thomas; Bonnefond, Amélie; Andersson, Ehm; Bouatia-Naji, Nabila; Holmkvist, Johan; Wegner, Lise; Grarup, Niels; Gjesing, Anette P; Banasik, Karina; Cavalcanti-Proença, Christine; Marchand, Marion; Vaxillaire, Martine; Charpentier, Guillaume; Jarvelin, Marjo-Riitta; Tichet, Jean; Balkau, Beverley; Marre, Michel; Lévy-Marchal, Claire; Faerch, Kristine; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Poulsen, Pernille; Vaag, Allan; Dina, Christian; Hansen, Torben; Pedersen, Oluf; Froguel, Philippe; Sparsø, Thomas; Bonnefond, Amélie; Andersson, Ehm; Bouatia-Naji, Nabila; Holmkvist, Johan; Wegner, Lise; Grarup, Niels; Gjesing, Anette P; Banasik, Karina; Cavalcanti-Proença, Christine; Marchand, Marion; Vaxillaire, Martine; Charpentier, Guillaume; Jarvelin, Marjo-Riitta; Tichet, Jean; Balkau, Beverley; Marre, Michel; Lévy-Marchal, Claire; Faerch, Kristine; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Poulsen, Pernille; Vaag, Allan; Dina, Christian; Hansen, Torben; Pedersen, Oluf; Froguel, Philippe.

    In: Diabetes, Vol. 58, No. 6, 2009, p. 1450-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people. / Sparsø, Thomas; Hussain, Meena S; Andersen, Gitte; Hainerova, Irena; Borch-Johnsen, Knut; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Molecular Genetics and Metabolism, Vol. 90, No. 2, 2007, p. 205-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites. / Sparsø, Thomas; Hussain, Meena Shaheen; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Hansen, Torben; Pedersen, Oluf; Andersen, Gitte.

    In: Molecular Genetics and Metabolism, Vol. 92, No. 3, 2007, p. 278-282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. / Speliotes, Elizabeth K; Willer, Cristen J; Berndt, Sonja I; Monda, Keri L; Thorleifsson, Gudmar; Jackson, Anne U; Allen, Hana Lango; Lindgren, Cecilia M; Luan, Jian'an; Mägi, Reedik; Randall, Joshua C; Vedantam, Sailaja; Winkler, Thomas W; Lu, Qi; Workalemahu, Tsegaselassie; Heid, Iris M; Steinthorsdottir, Valgerdur; Stringham, Heather M; Weedon, Michael N; Wheeler, Eleanor; Wood, Andrew R; Ferreira, Teresa; Weyant, Robert J; Segrè, Ayellet V; Estrada, Karol; Liang, Liming; Nemesh, James; Park, Ju-Hyun; Gustafsson, Stefan; Oskari Kilpeläinen, Tuomas; Yang, Jian; Bouatia-Naji, Nabila; Esko, Tõnu; Feitosa, Mary F; Kutalik, Zoltán; Mangino, Massimo; Raychaudhuri, Soumya; Scherag, Andre; Smith, Albert Vernon; Welch, Ryan; Zhao, Jing Hua; Aben, Katja K; Absher, Devin M; Amin, Najaf; Dixon, Anna L; Gjesing, Anette P; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; MAGIC.

    In: Nature Genetics, Vol. 42, No. 11, 01.11.2010, p. 937-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. / Stacey, Simon N; Sulem, Patrick; Jonasdottir, Aslaug; Masson, Gisli; Gudmundsson, Julius; Gudbjartsson, Daniel F; Magnusson, Olafur T; Gudjonsson, Sigurjon A; Sigurgeirsson, Bardur; Thorisdottir, Kristin; Ragnarsson, Rafn; Benediktsdottir, Kristrun R; Nexø, Bjørn Andersen; Tjønneland, Anne; Overvad, Kim; Rudnai, Peter; Gurzau, Eugene; Koppova, Kvetoslava; Hemminki, Kari; Corredera, Cristina; Fuentelsaz, Victoria; Grasa, Pilar; Navarrete, Sebastian; Fuertes, Fernando; García-Prats, Maria D; Sanambrosio, Enrique; Panadero, Angeles; De Juan, Ana; Garcia, Almudena; Rivera, Fernando; Planelles, Dolores; Soriano, Virtudes; Requena, Celia; Aben, Katja K; van Rossum, Michelle M; Cremers, Ruben G H M; van Oort, Inge M; van Spronsen, Dick-Johan; Schalken, Jack A; Peters, Wilbert H M; Helfand, Brian T; Donovan, Jenny L; Hamdy, Freddie C; Badescu, Daniel; Codreanu, Ovidiu; Banasik, Karina; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; Swedish Low-risk Colorectal Cancer Study Group.

    In: Nature Genetics, Vol. 43, No. 11, 01.01.2011, p. 1098-1103.

    Research output: Contribution to journalLetterResearchpeer-review

  9. Published

    A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study. / Staiger, Harald; Stancáková, Alena; Zilinskaite, Jone; Vänttinen, Markku; Hansen, Torben; Marini, Maria Adelaide; Hammarstedt, Ann; Jansson, Per-Anders; Sesti, Giorgio; Smith, Ulf; Pedersen, Oluf; Laakso, Markku; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich.

    In: Diabetes, Vol. 57, No. 2, 2008, p. 514-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. / Stancáková, Alena; Pihlajamäki, Jussi; Kuusisto, Johanna; Stefan, Norbert; Fritsche, Andreas; Häring, Hans; Andreozzi, Francesco; Succurro, Elena; Sesti, Giorgio; Boesgaard, Trine Welløv; Hansen, Torben; Pedersen, Oluf; Jansson, Per Anders; Hammarstedt, Ann; Smith, Ulf; Laakso, Markku; EUGENE2 Consortium.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 5, 2008, p. 1924-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. / Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Reynisdottir, Inga; Benediktsson, Rafn; Jonsdottir, Thorbjorg; Walters, G Bragi; Styrkarsdottir, Unnur; Gretarsdottir, Solveig; Emilsson, Valur; Ghosh, Shyamali; Baker, Adam; Snorradottir, Steinunn; Bjarnason, Hjordis; Ng, Maggie C Y; Hansen, Torben; Bagger, Yu; Wilensky, Robert L; Reilly, Muredach P; Adeyemo, Adebowale; Chen, Yuanxiu; Zhou, Jie; Gudnason, Vilmundur; Chen, Guanjie; Huang, Hanxia; Lashley, Kerrie; Doumatey, Ayo; So, Wing-Yee; Ma, Ronald C Y; Andersen, Gitte; Borch-Johnsen, Knut; Jorgensen, Torben; van Vliet-Ostaptchouk, Jana V; Hofker, Marten H; Wijmenga, Cisca; Christiansen, Claus; Rader, Daniel J; Rotimi, Charles; Gurney, Mark; Chan, Juliana C N; Pedersen, Oluf; Sigurdsson, Gunnar; Gulcher, Jeffrey R; Thorsteinsdottir, Unnur; Kong, Augustine; Stefansson, Kari.

    In: Nature Genetics, Vol. 39, No. 6, 2007, p. 770-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes. / Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Sulem, Patrick; Helgason, Hannes; Grarup, Niels; Sigurdsson, Asgeir; Helgadottir, Hafdis T; Johannsdottir, Hrefna; Magnusson, Olafur T; Gudjonsson, Sigurjon A; Justesen, Johanne M; Harder, Marie N; Jørgensen, Marit E; Christensen, Cramer; Brandslund, Ivan; Sandbæk, Annelli; Lauritzen, Torsten; Vestergaard, Henrik; Linneberg, Allan; Jørgensen, Torben; Hansen, Torben; Daneshpour, Maryam S; Fallah, Mohammad-Sadegh; Hreidarsson, Astradur B; Sigurdsson, Gunnar; Azizi, Fereidoun; Benediktsson, Rafn; Masson, Gisli; Helgason, Agnar; Kong, Augustine; Gudbjartsson, Daniel F; Pedersen, Oluf; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 46, No. 3, 26.01.2014, p. 294-300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    TFAP2B influences the effect of dietary fat on weight loss under energy restriction. / Stocks, Tanja; Angquist, Lars; Banasik, Karina; Harder, Marie Neergaard; Taylor, Moira A; Hager, Jörg; Arner, Peter; Oppert, Jean-Michel; Martinez, J Alfredo; Polak, Jan; Rousseau, Francis; Langin, Dominique; Rössner, Stephan; Holst, Claus; Macdonald, Ian A; Kamatani, Yoichiro; Pfeiffer, Andreas F H; Kunesova, Marie; Saris, Wim H M; Hansen, Torben; Pedersen, Oluf; Astrup, Arne; Sørensen, Thorkild I.A.

    In: P L o S One, Vol. 7, No. 8, 2012, p. e43212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Blood pressure levels in male carriers of Arg82Cys in CD300LG. / Støy, Julie; Grarup, Niels; Hørlyck, Arne; Ibsen, Liselotte; Rungby, Jørgen; Poulsen, Per Løgstrup; Brandslund, Ivan; Christensen, Cramer; Hansen, Torben; Pedersen, Oluf; Møller, Niels; Kampmann, Ulla.

    In: PLOS ONE, Vol. 9, No. 10, e109646, 2014.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG : a novel genometabolic cross-link between CD300LG and common metabolic phenotypes. / Støy, Julie; Kampmann, Ulla; Mengel, Annette; Magnusson, Nils E; Jessen, Niels; Grarup, Niels; Rungby, Jørgen; Stødkilde-Jørgensen, Hans; Brandslund, Ivan; Christensen, Cramer; Hansen, Torben; Pedersen, Oluf; Møller, Niels.

    In: BMJ open diabetes research & care, Vol. 3, No. 1, e000095, 2015, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants. / Sun, Jihua; Have, Christian Theil; Hollensted, Mette; Grarup, Niels; Linneberg, Allan; Pedersen, Oluf; Nielsen, Jens Steen; Rungby, Jørgen; Christensen, Cramer; Brandslund, Ivan; Kristiansen, Karsten; Jun, Wang; Hansen, Torben; Gjesing, Anette P.

    In: PLoS ONE, Vol. 14, No. 8, e0220805, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Metagenomic species profiling using universal phylogenetic marker genes. / Sunagawa, Shinichi; Mende, Daniel R.; Zeller, Georg; Izquierdo-Carrasco, Fernando; Berger, Simon A.; Kultima, Jens Roat; Coelho, Luis Pedro; Arumugam, Manimozhiyan; Tap, Julien; Nielsen, Henrik Bjørn; Rasmussen, Simon; Brunak, Søren; Pedersen, Oluf Borbye; Guarner, Francisco; de Vos, Willem M; Wang, Jun; Li, Junhua; Doré, Joël; Ehrlich, S Dusko; Stamatakis, Alexandros; Bork, Peer.

    In: Nature Methods, Vol. 10, No. 12, 2013, p. 1196-1199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. / Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P; Manning, Alisa K; Grarup, Niels; Sim, Xueling; Barnes, Daniel R; Witkowska, Kate; Staley, James R; Tragante, Vinicius; Tukiainen, Taru; Yaghootkar, Hanieh; Masca, Nicholas; Freitag, Daniel F; Ferreira, Teresa; Giannakopoulou, Olga; Tinker, Andrew; Harakalova, Magdalena; Mihailov, Evelin; Liu, Chunyu; Kraja, Aldi T; Nielsen, Sune Fallgaard; Rasheed, Asif; Samuel, Maria; Zhao, Wei; Bonnycastle, Lori L; Jackson, Anne U; Narisu, Narisu; Swift, Amy J; Southam, Lorraine; Marten, Jonathan; Huyghe, Jeroen R; Stančáková, Alena; Fava, Cristiano; Ohlsson, Therese; Matchan, Angela; Stirrups, Kathleen E; Bork-Jensen, Jette; Gjesing, Anette P; Kontto, Jukka; Perola, Markus; Shaw-Hawkins, Susan; Havulinna, Aki S; Husemoen, Lise L; Linneberg, Allan; Hansen, Torben; Pedersen, Oluf; Nordestgaard, Børge Grønne; CHARGE-Heart Failure Consortium.

    In: Nature Genetics, Vol. 48, No. 10, 12.09.2016, p. 1151-1161.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis. / Sustarsic, Elahu G; Ma, Tao; Lynes, Matthew D; Larsen, Michael; Karavaeva, Iuliia; Havelund, Jesper F; Nielsen, Carsten H; Jedrychowski, Mark P; Moreno-Torres, Marta; Lundh, Morten; Plucinska, Kaja; Jespersen, Naja Z; Grevengoed, Trisha J; Kramar, Barbara; Peics, Julia; Hansen, Jakob B; Shamsi, Farnaz; Forss, Isabel; Neess, Ditte; Keipert, Susanne; Wang, Jianing; Stohlmann, Katharina; Brandslund, Ivan; Christensen, Cramer; Jørgensen, Marit E; Linneberg, Allan; Pedersen, Oluf; Kiebish, Michael A; Qvortrup, Klaus; Han, Xianlin; Pedersen, Bente Klarlund; Jastroch, Martin; Mandrup, Susanne; Kjær, Andreas; Gygi, Steven P; Hansen, Torben; Gillum, Matthew P; Grarup, Niels; Emanuelli, Brice; Nielsen, Søren; Scheele, Camilla; Tseng, Yu-Hua; Færgeman, Nils J; Gerhart-Hines, Zachary.

    In: Cell Metabolism, Vol. 28, No. 1, 2018, p. 159-174.e11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic risk scores link body fat distribution with specific cardiometabolic profiles. / Svendstrup, Mathilde; Sandholt, Camilla H; Andersson Galijatovic, Ehm Astrid; Linneberg, Allan; Jørgensen, Torben; Sørensen, Thorkild I A; Pedersen, Oluf; Grarup, Niels; Hansen, Torben; Vestergaard, Henrik.

    In: Obesity, Vol. 24, No. 8, 08.2016, p. 1778-1785.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Prospective studies exploring the possible impact of an ID3 polymorphism on changes in obesity measures. / Svendstrup, Mathilde; Appel, Emil V.R.; Sandholt, Camilla H.; Ahluwalia, Tarunveer S.; Ängquist, Lars H.; Thuesen, Betina H.; Jørgensen, Marit E.; Pedersen, Oluf; Grarup, Niels; Hansen, Torben; Sørensen, Thorkild I.A.; Vestergaard, Henrik.

    In: Obesity, Vol. 26, No. 4, 2018, p. 747-754.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans. / Søberg, Susanna; Sandholt, Camilla Helene; Z. Jespersen, Naja ; Toft, Ulla; L. Madsen, Anja ; von Holstein-Rathlou, Stephanie Ø; Grevengoed, Trisha Jean; Christensen, Karl Bang; Bredie, Wender; Potthoff, Matthew J; P. J. Solomon, Thomas; Schéele, Camilla Charlotte; Linneberg, Allan René; Jørgensen, Torben; Pedersen, Oluf Borbye; Hansen, Torben; Gillum, Matthew Paul; Grarup, Niels.

    In: Cell Metabolism, Vol. 25, No. 5, 2017, p. 1045-1053.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes. / Sørensen, Anne-Sofie; Kjær, Laura Kofoed; Petersen, Kasper Meidahl; Henriksen, Trine; Cejvanovic, Vanja; Pedersen, Oluf; Hansen, Torben; Christensen, Cramer Kjeldahl; Brandslund, Ivan; Poulsen, Henrik Enghusen.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 77, No. 4, 2017, p. 253-258.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Sequencing and de novo assembly of 150 genomes from Denmark as a population reference. / Sørensen, Lasse Maretty; Jensen, Jacob Malte; Petersen, Bent; Sibbesen, Jonas Andreas; Liu, Siyang; Villesen, Palle; Skov, Laurits; Belling, Kirstine G; Have, Christian Theil; Izarzugaza, Jose M. G.; Grosjean, Marie; Bork-Jensen, Jette; Grove, Jakob; Als, Thomas D.; Huang, Shujia; Chang, Yuqi; Xu, Ruiqi; Ye, Weijian; Rao, Junhua; Guo, Xiaosen; Sun, Jihua; Cao, Hongzhi; Ye, Chen; van Beusekom, Johan; Espeseth, Thomas; Flindt, Esben; Friborg, Rune M.; Halager, Anders E.; Le Hellard, Stephanie; Hultman, Christina M.; Lescai, Francesco; Li, Shengting; Lund, Ole; Løngren, Peter; Mailund, Thomas; Matey-Hernandez, Maria Luisa; Mors, Ole; Pedersen, Christian N. S.; Sicheritz-Pontén, Thomas; Sullivan, Patrick; Syed, Ali; Westergaard, David; Yadav, Rachita; Li, Ning; Xu, Xun; Hansen, Torben; Krogh, Anders; Bolund, Lars; Sørensen, Thorkild I. A.; Pedersen, Oluf Borbye; Gupta, Ramneek; Rasmussen, Simon; Besenbacher, Søren; Børglum, Anders D.; Wang, Jun; Eiberg, Hans Rudolf Lytchoff; Kristiansen, Karsten; Brunak, Søren; Schierup, Mikkel Heide.

    In: Nature, Vol. 548, No. 7665, 03.08.2017, p. 87-91.

    Research output: Contribution to journalLetterResearchpeer-review

  25. Published

    Genetic polymorphisms and weight loss in obesity : a randomised trial of hypo-energetic high- versus low-fat diets. / Sørensen, Thorkild I.A.; Boutin, Philippe; Taylor, Moira A.; Larsen, Lesli H.; Verdich, Camilla; Petersen, Liselotte; Holst, Claus; Echwald, Søren M.; Dina, Christian; Toubro, Søren; Petersen, Martin; Polak, Jan; Clément, Karine; Martinez, J. Alfredo; Langin, Dominique; Oppert, Jean-Michel; Stich, Vladimir; Macdonald, Ian; Arner, Peter; Saris, Wim H. M.; Pedersen, Oluf; Astrup, Arne; Froguel, Philippe.

    In: PLoS Clinical Trials, Vol. 12, No. 2, 2006, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 919113