Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2008
  2. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation. / Sparsø, T; Andersen, G; Albrechtsen, Anders; Jørgensen, T; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Wasson, J; Permutt, M A; Glaser, B; Madsbad, S; Pedersen, Oluf; Hansen, T.

    In: Diabetologia, Vol. 51, No. 9, 2008, p. 1646-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes (Diabetologia DOI : 10.1007/s00125-007-0865-z). / Sparsø, T.; Andersen, G.; Nielsen, T.; Burgdorf, K. S.; Gjesing, A. P.; Nielsen, A. L.; Albrechtsen, A.; Rasmussen, S. S.; Jørgensen, T.; Borch-Johnsen, K.; Sandbæk, A.; Lauritzen, T.; Madsbad, S.; Hansen, T.; Pedersen, O.

    In: Diabetologia, Vol. 51, No. 2, 01.02.2008.

    Research output: Contribution to journalComment/debateResearchpeer-review

  4. Published

    A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study. / Staiger, Harald; Stancáková, Alena; Zilinskaite, Jone; Vänttinen, Markku; Hansen, Torben; Marini, Maria Adelaide; Hammarstedt, Ann; Jansson, Per-Anders; Sesti, Giorgio; Smith, Ulf; Pedersen, Oluf; Laakso, Markku; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich.

    In: Diabetes, Vol. 57, No. 2, 2008, p. 514-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. / Stancáková, Alena; Pihlajamäki, Jussi; Kuusisto, Johanna; Stefan, Norbert; Fritsche, Andreas; Häring, Hans; Andreozzi, Francesco; Succurro, Elena; Sesti, Giorgio; Boesgaard, Trine Welløv; Hansen, Torben; Pedersen, Oluf; Jansson, Per Anders; Hammarstedt, Ann; Smith, Ulf; Laakso, Markku; EUGENE2 Consortium.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 5, 2008, p. 1924-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. / Unoki, Hiroyuki; Takahashi, Atsushi; Kawaguchi, Takahisa; Hara, Kazuo; Horikoshi, Momoko; Andersen, Gitte; Ng, Daniel P K; Holmkvist, Johan; Borch-Johnsen, Knut; Jørgensen, Torben; Sandbæk, Annelli; Lauritzen, Torsten; Hansen, Torben; Nurbaya, Siti; Tsunoda, Tatsuhiko; Kubo, Michiaki; Babazono, Tetsuya; Hirose, Hiroshi; Hayashi, Matsuhiko; Iwamoto, Yasuhiko; Kashiwagi, Atsunori; Kaku, Kohei; Kawamori, Ryuzo; Tai, E Shyong; Pedersen, Oluf; Kamatani, Naoyuki; Kadowaki, Takashi; Kikkawa, Ryuichi; Nakamura, Yusuke; Maeda, Shiro.

    In: Nature Genetics, Vol. 40, No. 9, 2008, p. 1098-1102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals. / Vimaleswaran, Karani Santhanakrishnan; Luan, Jian'an; Andersen, Gitte; Muller, Y Li; Wheeler, Eleanor; Brito, Ema C; O'Rahilly, Stephen; Pedersen, Oluf; Baier, Leslie J; Knowler, William C; Barroso, Inês; Wareham, Nicholas J; Loos, Ruth J F; Franks, Paul W.

    In: Journal of Applied Physiology, Vol. 105, No. 4, 2008, p. 1352-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins. / Wegner, Lise; Hussain, Meena S; Pilgaard, Kasper; Hansen, Torben; Pedersen, Oluf; Vaag, Allan; Poulsen, Inge Pernille.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 10, 2008, p. 4013-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. / Zeggini, Eleftheria; Scott, Laura J; Saxena, Richa; Voight, Benjamin F; Marchini, Jonathan L; Hu, Tianle; de Bakker, Paul I W; Abecasis, Gonçalo R; Almgren, Peter; Andersen, Gitte; Ardlie, Kristin; Boström, Kristina Bengtsson; Bergman, Richard N; Bonnycastle, Lori L; Borch-Johnsen, Knut; Burtt, Noël P; Chen, Hong; Chines, Peter S; Daly, Mark J; Deodhar, Parimal; Ding, Chia-Jen; Doney, Alex S F; Duren, William L; Elliott, Katherine S; Erdos, Michael R; Frayling, Timothy M; Freathy, Rachel M; Gianniny, Lauren; Grallert, Harald; Grarup, Niels; Groves, Christopher J; Guiducci, Candace; Hansen, Torben; Herder, Christian; Hitman, Graham A; Hughes, Thomas E; Isomaa, Bo; Jackson, Anne U; Jørgensen, Torben; Kong, Augustine; Kubalanza, Kari; Kuruvilla, Finny G; Kuusisto, Johanna; Langenberg, Claudia; Lango, Hana; Lauritzen, Torsten; Li, Yun; Lindgren, Cecilia M; Lyssenko, Valeriya; Wellcome Trust Case Control Consortium ; Pedersen, Oluf.

    In: Nature Genetics, Vol. 40, No. 5, 2008, p. 638-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2007
  11. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis. / Dahlman, Ingrid; Dicker, Andrea; Jiao, Hong; Kere, Juha; Blomqvist, Lennart; van Harmelen, Vanessa; Hoffstedt, Johan; Borch-Johnsen, Knut; Jorgensen, Torben; Hansen, Torben; Pedersen, Oluf; Laakso, Markku; Arner, Peter.

    In: American Journal of Human Genetics, Vol. 80, No. 6, 2007, p. 1115-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Rosiglitazone monotherapy for type 2 diabetes mellitus-too soon to ADOPT? / Gaede, Peter; Pedersen, Oluf.

    In: Nature clinical practice. Endocrinology & metabolism, Vol. 3, No. 6, 2007, p. 456-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects. / Gjesing, A P; Andersen, G; Albrechtsen, A; Glümer, C; Borch-Johnsen, K; Jørgensen, T; Hansen, T; Pedersen, O.

    In: Diabetic Medicine, Vol. 24, No. 4, 04.2007, p. 392-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects. / Gjesing, A P; Andersen, G; Burgdorf, K S; Borch-Johnsen, K; Jørgensen, T; Hansen, T; Pedersen, O.

    In: Diabetologia, Vol. 50, No. 3, 03.2007, p. 563-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects : validation and extension of genome-wide association studies. / Grarup, Niels; Rose, Chrisian S; Andersson, Ehm A; Andersen, Gitte; Nielsen, Arne L; Albrechtsen, Anders; Clausen, Jesper O; Rasmussen, Signe S; Jørgensen, Torben; Sandbaek, Annelli; Lauritzen, Torsten; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 56, No. 12, 2007, p. 3105-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects. / Grarup, Niels; Andersen, Mette K; Andreasen, Camilla H; Albrechtsen, Anders; Borch-Johnsen, Knut; Jørgensen, Torben; Auwerx, Johan; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 92, No. 1, 2007, p. 363-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. / Gudmundsson, Julius; Sulem, Patrick; Steinthorsdottir, Valgerdur; Bergthorsson, Jon T; Thorleifsson, Gudmar; Manolescu, Andrei; Rafnar, Thorunn; Gudbjartsson, Daniel; Agnarsson, Bjarni A; Baker, Adam; Sigurdsson, Asgeir; Benediktsdottir, Kristrun R; Jakobsdottir, Margret; Blondal, Thorarinn; Stacey, Simon N; Helgason, Agnar; Gunnarsdottir, Steinunn; Olafsdottir, Adalheidur; Kristinsson, Kari T; Birgisdottir, Birgitta; Ghosh, Shyamali; Thorlacius, Steinunn; Magnusdottir, Dana; Stefansdottir, Gerdur; Kristjansson, Kristleifur; Bagger, Yu; Wilensky, Robert L; Reilly, Muredach P; Morris, Andrew D; Kimber, Charlotte H; Adeyemo, Adebowale; Chen, Yuanxiu; Zhou, Jie; So, Wing-Yee; Tong, Peter C Y; Ng, Maggie C Y; Hansen, Torben; Andersen, Gitte; Borch-Johnsen, Knut; Jorgensen, Torben; Tres, Alejandro; Fuertes, Fernando; Ruiz-Echarri, Manuel; Asin, Laura; Saez, Berta; van Boven, Erica; Klaver, Siem; Swinkels, Dorine W; Aben, Katja K; Graif, Theresa; Cashy, John; Suarez, Brian K; van Vierssen Trip, Onco; Frigge, Michael L; Ober, Carole; Hofker, Marten H; Wijmenga, Cisca; Christiansen, Claus; Rader, Daniel J; Palmer, Colin N A; Rotimi, Charles; Chan, Juliana C N; Pedersen, Oluf; Sigurdsson, Gunnar; Benediktsson, Rafn; Jonsson, Eirikur; Einarsson, Gudmundur V; Mayordomo, Jose I; Catalona, William J; Kiemeney, Lambertus A; Barkardottir, Rosa B; Gulcher, Jeffrey R; Thorsteinsdottir, Unnur; Kong, Augustine; Stefansson, Kari.

    In: Nature Genetics, Vol. 39, No. 8, 2007, p. 977-983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Melanocortin 4 receptor mutations in obese Czech children : studies of prevalence, phenotype development, weight reduction response, and functional analysis. / Hainerová, Irena; Larsen, Lesli H; Holst, Birgitte; Finková, Marie; Hainer, Vojtech; Lebl, Jan; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 92, No. 9, 2007, p. 3689-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The BIGTT test : a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance. / Hansen, Torben; Drivsholm, Thomas; Urhammer, Søren A; Palacios, Rene T; Vølund, Aage; Borch-Johnsen, Knut; Pedersen, Oluf.

    In: Diabetes Care, Vol. 30, No. 2, 2007, p. 257-262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. / Helgason, Agnar; Pálsson, Snaebjörn; Thorleifsson, Gudmar; Grant, Struan F A; Emilsson, Valur; Gunnarsdottir, Steinunn; Adeyemo, Adebowale; Chen, Yuanxiu; Chen, Guanjie; Reynisdottir, Inga; Benediktsson, Rafn; Hinney, Anke; Hansen, Torben; Andersen, Gitte; Borch-Johnsen, Knut; Jorgensen, Torben; Schäfer, Helmut; Faruque, Mezbah; Doumatey, Ayo; Zhou, Jie; Wilensky, Robert L; Reilly, Muredach P; Rader, Daniel J; Bagger, Yu; Christiansen, Claus; Sigurdsson, Gunnar; Hebebrand, Johannes; Pedersen, Oluf; Thorsteinsdottir, Unnur; Gulcher, Jeffrey R; Kong, Augustine; Rotimi, Charles; Stefánsson, Kári.

    In: Nature Genetics, Vol. 39, No. 2, 2007, p. 218-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites. / Jensen, Dorit P; Andersen, Mette K; Hansen, Lars; Eiberg, Hans; Borch-Johnsen, Knut; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Andreasen, Camilla H.

    In: Journal of Molecular Medicine, Vol. 85, No. 5, 2007, p. 445-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy. / Kamiyama, Masumi; Kobayashi, Masaaki; Araki, Shin-ichi; Iida, Aritoshi; Tsunoda, Tatsuhiko; Kawai, Koichi; Imanishi, Masahito; Nomura, Makoto; Babazono, Tetsuya; Iwamoto, Yasuhiko; Kashiwagi, Atsunori; Kaku, Kohei; Kawamori, Ryuzou; Ng, Daniel P K; Hansen, Torben; Gaede, Peter; Pedersen, Oluf; Nakamura, Yusuke; Maeda, Shiro.

    In: Human Genetics, Vol. 122, No. 3-4, 2007, p. 397-407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes. / Larsen, L H; Rose, C S; Sparsø, T; Overgaard, J; Torekov, Signe Sørensen; Grarup, N; Jensen, D P; Albrechtsen, Anders; Andersen, G; Ek, J; Glümer, C; Borch-Johnsen, K; Jørgensen, T; Hansen, T; Pedersen, O.

    In: International Journal of Obesity, Vol. 31, No. 2, 2007, p. 365-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes. / Sparsø, T; Andersen, G; Nielsen, T; Burgdorf, K S; Gjesing, Anette Marianne Prior; Nielsen, A L; Albrechtsen, Anders; Rasmussen, S S; Jørgensen, Torben; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Madsbad, S; Hansen, T; Pedersen, Oluf.

    In: Diabetologia, Vol. 51, No. 1, 2007, p. 70-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people. / Sparsø, Thomas; Hussain, Meena S; Andersen, Gitte; Hainerova, Irena; Borch-Johnsen, Knut; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Molecular Genetics and Metabolism, Vol. 90, No. 2, 2007, p. 205-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites. / Sparsø, Thomas; Hussain, Meena Shaheen; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Hansen, Torben; Pedersen, Oluf; Andersen, Gitte.

    In: Molecular Genetics and Metabolism, Vol. 92, No. 3, 2007, p. 278-282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. / Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Reynisdottir, Inga; Benediktsson, Rafn; Jonsdottir, Thorbjorg; Walters, G Bragi; Styrkarsdottir, Unnur; Gretarsdottir, Solveig; Emilsson, Valur; Ghosh, Shyamali; Baker, Adam; Snorradottir, Steinunn; Bjarnason, Hjordis; Ng, Maggie C Y; Hansen, Torben; Bagger, Yu; Wilensky, Robert L; Reilly, Muredach P; Adeyemo, Adebowale; Chen, Yuanxiu; Zhou, Jie; Gudnason, Vilmundur; Chen, Guanjie; Huang, Hanxia; Lashley, Kerrie; Doumatey, Ayo; So, Wing-Yee; Ma, Ronald C Y; Andersen, Gitte; Borch-Johnsen, Knut; Jorgensen, Torben; van Vliet-Ostaptchouk, Jana V; Hofker, Marten H; Wijmenga, Cisca; Christiansen, Claus; Rader, Daniel J; Rotimi, Charles; Gurney, Mark; Chan, Juliana C N; Pedersen, Oluf; Sigurdsson, Gunnar; Gulcher, Jeffrey R; Thorsteinsdottir, Unnur; Kong, Augustine; Stefansson, Kari.

    In: Nature Genetics, Vol. 39, No. 6, 2007, p. 770-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 919113