Nikos Hatzakis

Nikos Hatzakis

Associate Professor


  1. 2019
  2. Published

    Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization. / Bech, Esben M.; Kaiser, Anette; Bellmann-Sickert, Kathrin; Nielsen, Søren S.-R.; Sørensen, Kasper K.; Elster, Lisbeth; Hatzakis, Nikos; Pedersen, Søren L.; Beck-Sickinger, Annette G.; Jensen, Knud J.

    In: Molecular Pharmaceutics, Vol. 16, No. 8, 2019, p. 3665-3677.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2018
  4. Published

    Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. / Stella, Stefano; Mesa, Pablo; Thomsen, Johannes; Paul, Bijoya; Alcón, Pablo; Jensen, Simon Bo; Saligram, Bhargav; Moses, Matias Emil; Hatzakis, Nikos S.; Montoya, Guillermo.

    In: Cell, Vol. 175, No. 7, 13.12.2018, p. 1856-1871.e21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength. / Bavishi, Krutika; Li, Darui; Eiersholt, Stine; Hooley, Emma Nicole; Petersen, Troels Christian; Møller, Birger Lindberg; Hatzakis, Nikos; Laursen, Tomas.

    In: Scientific Reports, Vol. 8, 6817, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Functionalized Gold Nanoclusters Identify Highly Reactive Oxygen Species in Living Organisms. / Xie, Yangzhouyun; Xianyu, Yunlei; Wang, Nuoxin; Yan, Zhaoyang; Liu, Yong; Zhu, Kui; Hatzakis, Nikos; Jiang, Xingyu.

    In: Advanced Functional Materials, Vol. 28, No. 14, 1702026, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2017
  8. Published

    Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells. / Rosholm, Kadla R.; Leijnse, Natascha; Mantsiou, Anna; Tkach, Vadym; Pedersen, Søren Ljungberg; Wirth, Volker F.; Oddershede, Lene B.; Jensen, Knud J.; Martinez, Karen L.; Hatzakis, Nikos S.; Bendix, Pól Martin; Callan-Jones, Andrew; Stamou, Dimitrios.

    In: Nature Chemical Biology, Vol. 13, No. 7, 08.05.2017, p. 724-729.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effects of membrane curvature and pH on proton pumping activity of single cytochrome bo3 enzymes. / Li, Mengqiu; Khan, Sanobar; Rong, Honglin; Tuma, Roman; Hatzakis, Nikos; Jeuken, Lars J. C.

    In: Biochimica et Biophysica Acta - Bioenergetics, Vol. 1858, No. 9, 2017, p. 763-770.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment. / Larsen, Jannik B.; Kennard, Celeste; Pedersen, Søren L.; Jensen, Knud J.; Uline, Mark J.; Hatzakis, Nikos S.; Stamou, Dimitrios.

    In: Biophysical Journal, Vol. 113, No. 6, 2017, p. 1269-1279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2016
  12. Published

    Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum. / Laursen, Tomas; Borch-Jensen, Jonas; Baden, Camilla Knudsen; Bavishi, Krutika; Torta, Federico; Martens, Helle Juel; Silvestro, Daniele; Hatzakis, Nikos; Wenk, Markus R; Dafforn, Timothy R; Olsen, Carl Erik; Motawie, Mohammed Saddik; Hamberger, Björn Robert; Møller, Birger Lindberg; Bassard, Jean-Étienne André.

    In: Science (New York, N.Y.), Vol. 354, No. 6314, 2016, p. 890-893.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Direct observation of proton pumping by a eukaryotic P-type ATPase. / Veshaguri, Salome; Christensen, Sune Fang; Kemmer, Gerdi Christine; Ghale, Garima; Møller, Mads Peter; Lohr, Christina; Christensen, Andreas Lauge; Justesen, Bo Højen; Jørgensen, Ida Louise; Schiller, Jürgen; Hatzakis, Nikos; Grabe, Michael; Günther-Pomorski, Thomas; Stamou, Dimitrios.

    In: Science, Vol. 351, No. 6280, 2016, p. 1469-1473.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Links of conformational sampling to functional plasticity and clinical phenotypes by single molecule studies. / Moses, Matias Emil; Thodberg, Sara; Bavishi, Krutika; Eiersholt, Stine; Li, Darui; Stamou, Dimitrios; Møller, Birger Lindberg; Laursen, Tomas; Hatzakis, Nikos.

    In: Biophysical Society. Annual Meeting. Abstracts, Vol. 110, No. 3, 2016, p. 397A.

    Research output: Contribution to journalConference abstract in journalResearch

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