Niels Skotte

Niels Skotte

Postdoc

  • Proteomics Program

    Blegdamsvej 3, 2200 København N, Bygning 6, Building: 06-6-28

    Phone: +45 35 33 22 34

  1. 2019
  2. Published

    Functional Differences between Synaptic Mitochondria from the Striatum and the Cerebral Cortex. / Petersen, Maria Hvidberg; Willert, Cecilie Wennemoes; Andersen, Jens Velde; Waagepetersen, Helle Sønderby; Skotte, Niels Henning; Nørremølle, Anne.

    In: Neuroscience, Vol. 406, 05.2019, p. 432-443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease. / Andersen, Jens V.; Skotte, Niels H.; Aldana, Blanca I.; Nørremølle, Anne; Waagepetersen, Helle S.

    In: Cellular and Molecular Life Sciences, Vol. 76, No. 12, 2019, p. 2449-2461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2018
  5. Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease. / Southwell, Amber L; Kordasiewicz, Holly B; Langbehn, Douglas; Skotte, Niels H.; Parsons, Matthew P; Villanueva, Erika B; Caron, Nicholas S; Østergaard, Michael E; Anderson, Lisa M; Xie, Yuanyun; Cengio, Louisa Dal; Findlay-Black, Hailey; Doty, Crystal N; Fitsimmons, Bethany; Swayze, Eric E; Seth, Punit P; Raymond, Lynn A; Frank Bennett, C; Hayden, Michael R.

    In: Science Translational Medicine, Vol. 10, No. 461, eaar3959, 2018, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Site-specific characterization of endogenous SUMOylation across species and organs. / Hendriks, Ivo A.; Lyon, David; Su, Dan; Skotte, Niels H; Daniel, Jeremy A; Jensen, Lars J.; Nielsen, Michael L.

    In: Nature Communications, Vol. 9, 2456, 2018, p. 1-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published

    A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles. / Southwell, Amber L; Skotte, Niels H; Villanueva, Erika B; Østergaard, Michael E; Gu, Xiaofeng; Kordasiewicz, Holly B; Kay, Chris; Cheung, Daphne; Xie, Yuanyun; Waltl, Sabine; Dal Cengio, Louisa; Findlay-Black, Hailey; Doty, Crystal N; Petoukhov, Eugenia; Iworima, Diepiriye; Slama, Ramy; Ooi, Jolene; Pouladi, Mahmoud A; Yang, X William; Swayze, Eric E; Seth, Punit P; Hayden, Michael R.

    In: Human Molecular Genetics, Vol. 26, No. 6, 15.03.2017, p. 1115-1132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Palmitoylation of caspase-6 by HIP14 regulates its activation. / Skotte, Niels H; Sanders, Shaun S; Singaraja, Roshni R; Ehrnhoefer, Dagmar E; Vaid, Kuljeet; Qiu, Xiaofan; Kannan, Srinivasaragavan; Verma, Chandra; Hayden, Michael R.

    In: Cell Death and Differentiation, Vol. 24, 2017, p. 433-444.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2016
  12. Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD. / Riechers, Sean-Patrick; Butland, Stefanie; Deng, Yu; Skotte, Niels; Ehrnhoefer, Dagmar E; Russ, Jenny; Laine, Jean; Laroche, Melissa; Pouladi, Mahmoud A; Wanker, Erich E; Hayden, Michael R; Graham, Rona K.

    In: Human Molecular Genetics, Vol. 25, No. 8, 15.04.2016, p. 1600-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2015
  14. Huntingtin Haplotypes Provide Prioritized Target Panels for Allele-specific Silencing in Huntington Disease Patients of European Ancestry. / Kay, Chris; Collins, Jennifer A; Skotte, Niels H; Southwell, Amber L; Warby, Simon C; Caron, Nicholas S; Doty, Crystal N; Nguyen, Betty; Griguoli, Annamaria; Ross, Colin J; Squitieri, Ferdinando; Hayden, Michael R.

    In: Molecular Therapy, Vol. 23, No. 11, 11.2015, p. 1759-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2014
  16. In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides. / Southwell, Amber L; Skotte, Niels H; Kordasiewicz, Holly B; Østergaard, Michael E; Watt, Andrew T; Carroll, Jeffrey B; Doty, Crystal N; Villanueva, Erika B; Petoukhov, Eugenia; Vaid, Kuljeet; Xie, Yuanyun; Freier, Susan M; Swayze, Eric E; Seth, Punit P; Bennett, Clarence Frank; Hayden, Michael R.

    In: Molecular Therapy, Vol. 22, No. 12, 12.2014, p. 2093-106.

    Research output: Contribution to journalJournal articleResearchpeer-review

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