Morten Schak Nielsen

Morten Schak Nielsen

Associate Professor


  1. 2019
  2. Published

    Acute intramyocardial lipid accumulation in rats does not slow cardiac conduction per se. / Jensen, Christa F; Bartels, Emil D; Braunstein, Thomas H; Nielsen, Lars B; Holstein-Rathlou, Niels-Henrik; Axelsen, Lene N; Nielsen, Morten Schak.

    In: Physiological Reports, Vol. 7, No. 7, e14049, 04.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Modulating cardiac conduction during metabolic ischemia with perfusate sodium and calcium in guinea pig hearts. / George, Sharon A; Hoeker, Gregory; Calhoun, Patrick J; Entz, Michael; Raisch, Tristan B; King, D Ryan; Khan, Momina; Baker, Chandra; Gourdie, Robert G; Smyth, James W; Nielsen, Morten S; Poelzing, Steven.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 316, No. 4, 01.02.2019, p. H849-H861.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2018
  5. Published

    Uremia increases QRS duration after β-adrenergic stimulation in mice. / Thomsen, Morten B.; Nielsen, Morten S.; Aarup, Annemarie; Bisgaard, Line S.; Pedersen, Tanja X.

    In: Physiological Reports, Vol. 6, No. 13, e13720, 01.07.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Protein⁻Protein Interactions with Connexin 43: Regulation and Function. / Sorgen, Paul L; Trease, Andrew J; Spagnol, Gaelle; Delmar, Mario; Nielsen, Morten S.

    In: International Journal of Molecular Sciences, Vol. 19, No. 5, 1428, 10.05.2018.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Connexins and Disease. / Delmar, Mario; Laird, Dale W; Naus, Christian C; Nielsen, Morten S; Verselis, Vytautas K; White, Thomas W.

    In: Cold Spring Harbor perspectives in biology, Vol. 10, No. 9, a029348, 2018, p. 1-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Genetically modified animals as tools to personalize the study of arrhythmia mechanisms and treatment. / Cerrone, Marina; Nielsen, Morten Schak; Delmar, Mario.

    ESC CardioMed. ed. / A. John Camm; Thomas F. Lüscher; Gerald Maurer; Patrick W. Serruys. 3. ed. Oxford University Press, 2018.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    Probenecid inhibits α-adrenergic receptor-mediated vasoconstriction in the human leg vasculature. / Nyberg, Michael Permin; Piil, Peter Bergmann; Kiehn, Oliver Thistrup; Maagaard, Christian; Jørgensen, Tue Sparholt; Egelund, Jon; Isakson, Brant E; Nielsen, Morten Schak; Gliemann, Lasse; Hellsten, Ylva.

    In: Hypertension, Vol. 71, No. 1, 2018, p. 151-159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2017
  11. Published

    Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome. / Thorsen, Kasper; Dam, Vibeke S.; Kjaer-Sorensen, Kasper; Pedersen, Lisbeth N.; Skeberdis, V. Arvydas; Jurevicius, Jonas; Treinys, Rimantas; Petersen, Ida M. B. S.; Nielsen, Morten S.; Oxvig, Claus; Morth, J. Preben; Matchkov, Vladimir V.; Aalkjaer, Christian; Bundgaard, Henning; Jensen, Henrik K.

    In: Nature Communications, Vol. 8, 1696, 22.11.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Connexin Hemichannels in Astrocytes : An Assessment of Controversies Regarding Their Functional Characteristics. / Nielsen, Brian Skriver; Hansen, Daniel Bloch; Ransom, Bruce R.; Nielsen, Morten Schak; MacAulay, Nanna.

    In: Neurochemical Research, Vol. 42, No. 9, 09.2017, p. 2537–2550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Astrocytic connexin hemichannels are regulated by PKC phosphorylation in an isoform-specific manner. / MacAulay, N.; Alstrom, J. S.; Hansen, D. B.; Nielsen, M. S.

    In: Glia, Vol. 65, No. S1, S17-01, 2017, p. E64-E64.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Permeant-specific gating of connexin 30 hemichannels. / Nielsen, Brian Skriver; Alstrom, Jette Skov; Nicholson, Bruce; Nielsen, Morten Schak; Macaulay, Nanna.

    In: Journal of Biological Chemistry, Vol. 292, No. 49, 2017, p. 19999-20009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    T-type Ca(2+) channels and Autoregulation of Local Blood Flow. / Jensen, Lars Jørn; Nielsen, Morten Schak; Salomonsson, Max; Sørensen, Charlotte Mehlin.

    In: Channels (Austin), Vol. 11, No. 3, 2017, p. 183-195.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Unsupervised Idealization of Ion Channel Recordings by Minimum Description Length : Application to Human PIEZO1-Channels. / Gnanasambandam, Radhakrishnan; Nielsen, Morten S; Nicolai, Christopher; Sachs, Frederick; Hofgaard, Johannes P; Dreyer, Jakob K.

    In: Frontiers in Neuroinformatics, Vol. 11, 31, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2016
  18. Published

    Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43. / Morel, Sandrine; Christoffersen, Christina; Axelsen, Lene N; Montecucco, Fabrizio; Rochemont, Viviane; Frias, Miguel A; Mach, Francois; James, Richard W; Naus, Christian C; Chanson, Marc; Lampe, Paul D; Nielsen, Morten S; Nielsen, Lars B; Kwak, Brenda R.

    In: Cardiovascular Research, Vol. 109, 13.01.2016, p. 385-396.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2015
  20. Published

    Isoform-specific phosphorylation-dependent regulation of connexin hemichannels. / Alstrøm, Jette Skov; Hansen, Daniel Bloch; Nielsen, Morten Schak; MacAulay, Nanna.

    In: Journal of Neurophysiology, Vol. 114, No. 5, 15.11.2015, p. 3014-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium. / Skibsbye, Lasse; Wang, Xiaodong; Axelsen, Lene Nygaard; Bomholtz, Sofia Hammami; Nielsen, Morten Schak; Grunnet, Morten; Bentzen, Bo Hjorth; Jespersen, Thomas.

    In: Journal of Cardiovascular Pharmacology, Vol. 66, No. 2, 08.2015, p. 165-176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis. / Axelsen, Lene Nygaard; Callø, Kirstine; Braunstein, Thomas Hartig; Riemann, Mads; Hofgaard, Johannes Pauli; Liang, Bo; Jensen, Christa Funch; Olsen, Kristine Boisen; Bartels, Emil Daniel; Baandrup, Ulrik; Jespersen, Thomas; Nielsen, Lars Bo; von Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak.

    In: Cardiovascular Diabetology, Vol. 14, 87, 14.07.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Gap junctions-guards of excitability. / Stroemlund, Line Waring; Jensen, Christa Funch; Qvortrup, Klaus; Delmar, Mario; Nielsen, Morten Schak.

    In: Biochemical Society Transactions, Vol. 43, No. 3, 01.06.2015, p. 508-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Protein kinase C-dependent regulation of connexin43 gap junctions and hemichannels. / Alstrøm, Jette Skov; Stroemlund, Line Waring; Nielsen, Morten Schak; MacAulay, Nanna.

    In: Biochemical Society Transactions, Vol. 43, No. 3, 06.2015, p. 519-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sympathetic vasoconstriction takes an unexpected pannexin detour. / Schak Nielsen, Morten.

    In: Science signaling, Vol. 8, No. 364, fs4, 17.02.2015, p. 1-2.

    Research output: Contribution to journalComment/debateResearchpeer-review

  26. 2014
  27. Published

    Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels. / Hansen, Daniel Bloch; Ye, Zu-Cheng; Calloe, Kirstine; Braunstein, Thomas Hartig; Hofgaard, Johannes Pauli; Ransom, Bruce R; Nielsen, Morten Schak; MacAulay, Nanna.

    In: The Journal of Biological Chemistry, Vol. 289, No. 38, 19.09.2014, p. 26058-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Distinct permeation profiles of the connexin 30 and 43 hemichannels. / Hansen, Daniel Bloch; Braunstein, Thomas Hartig; Nielsen, Morten Schak; Macaulay, Nanna.

    In: FEBS letters, Vol. 588, No. 8, 17.04.2014, p. 1446-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2013
  30. Published

    Managing the complexity of communication: regulation of gap junctions by post-translational modification. / Axelsen, Lene Nygaard; Callø, Kirstine; von Holstein-Rathlou, Niels-Henrik; Nielsen, Morten S.

    In: Frontiers in Pharmacology, Vol. 4, 130, 10.2013, p. 1-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats. / Olsen, Kristine Boisen; Axelsen, Lene Nygaard; Braunstein, Thomas Hartig; Sørensen, Charlotte Mehlin; Andersen, Claus B; Ploug, Thorkil; von Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak.

    In: Cardiovascular Diabetology, Vol. 12, 2013, p. 19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2012
  33. Published

    Estimation of the effective intercellular diffusion coefficient in cell monolayers coupled by gap junctions. / Olesen, Niels Erik; Hofgaard, Johannes P; von Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak; Jacobsen, Jens Christian Brings.

    In: European Journal of Pharmaceutical Sciences, Vol. 46, No. 4, 2012, p. 222-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Gap Junctions. / Nielsen, Morten Schak; Axelsen, Lene Nygaard; Sorgen, Paul ; Verma, Vandana; Mario, Delmar; von Holstein-Rathlou, Niels-Henrik.

    In: Comprehensive Physiology, Vol. 2, 2012, p. 1981-2035.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Lateralized gap junctions in pulmonary hypertension - lost but not alone. / Nielsen, Morten Schak.

    In: Heart Rhythm, Vol. 9, No. 7, 2012, p. 1141-1142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2011
  37. Published

    Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions. / Mollerup, Sarah; Hofgaard, Johannes Pauli; Braunstein, Thomas Hartig; Kjenseth, A; Leithe, E; Rivedal, E; von Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak.

    In: Cell Communication & Adhesion (Print Edition), Vol. 18, No. 4, 21.09.2011, p. 57-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Angiotensin II does not acutely regulate conduction velocity in rat atrial tissue. / Olsen, Kristine B; Braunstein, Thomas H; Sørensen, Charlotte M; Axelsen, Lene Nygaard; Holstein-Rathlou, Niels-Henrik; Nielsen, Morten S.

    In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement, Vol. 71, No. 6, 06.07.2011, p. 492.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling. / Bonde, Marie Mi; Olsen, Kristine Boisen; Erikstrup, Niels; Speerschneider, Tobias; Lyngsø, Christina; Haunsø, Stig; Nielsen, Morten Schak; Sheikh, Søren Paludan; Hansen, Jakob Lerche.

    In: Regulatory Peptides, Vol. 167, No. 1, 2011, p. 21-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2010
  41. Published

    Connexin mimetic peptides fail to inhibit vascular conducted calcium responses in renal arterioles (American Journal of Physiology - Regulatory Integrative and Comparative Physiology (2008) 295, (R840-R847) DOI:10.1152/ajpregu.00491.2007). / Sorensen, Charlotte Mehlin; Salomonsson, Max; Braunstein, Thomas Hartig; Nielsen, Morten Schak; Holstein-Rathlou, Niels Henrik.

    In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology, Vol. 298, No. 1, 01.01.2010.

    Research output: Contribution to journalComment/debateResearchpeer-review

  42. 2009
  43. Published

    Myocyte-fibroblast interactions--risky connections. / Nielsen, Morten Schak.

    In: Heart Rhythm, Vol. 6, No. 11, 2009, p. 1650-1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Phosphorylation of connexin43 on serine 306 regulates electrical coupling. / Procida, Kristina; Jørgensen, Lone; Schmitt, Nicole; Delmar, Mario; Taffet, Steven M; Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak; Braunstein, Thomas Hartig.

    In: Heart Rhythm, Vol. 6, No. 11, 2009, p. 1632-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Quantification of gap junctional intercellular communication based on digital image analysis. / Hofgaard, Johannes P; Mollerup, Sarah; Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 297, No. 2, 2009, p. R243-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2008
  47. Published

    Connexin mimetic peptides fail to inhibit vascular conducted calcium responses in renal arterioles. / Sørensen, Charlotte Mehlin; Salomonsson, Max; Braunstein, Thomas Hartig; Nielsen, Morten Schak; Holstein-Rathlou, N.-H.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 295, No. 3, 2008, p. R840-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes. / Hofgaard, Johannes P; Banach, Kathrin; Mollerup, Sarah; Jørgensen, Helene Korvenius; Olesen, Søren Peter; Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak.

    In: Pflügers Archiv: European Journal of Physiology, Vol. 457, No. 2, 2008, p. 303-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    RXP-E: a connexin43-binding peptide that prevents action potential propagation block. / Lewandowski, Rebecca; Procida, Kristina; Vaidyanathan, Ravi; Coombs, Wanda; Jalife, José; Nielsen, Morten S; Taffet, Steven M; Delmar, Mario.

    In: Circulation Research, Vol. 103, No. 5, 2008, p. 519-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Synopsis of the International Gap Junction Conference in Elsinore, Denmark August 5-9, 2007. / Willecke, Klaus; Nielsen, Morten Schak.

    In: Cell Communication & Adhesion (Print Edition), Vol. 14, No. 6, 2008, p. 251-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2007
  52. Published

    Increasing gap junctional coupling: a tool for dissecting the role of gap junctions. / Axelsen, Lene Nygaard; Haugan, Ketil; Stahlhut, Martin; Kjølbye, Anne-Louise; Hennan, James K; Petersen, Jørgen Søberg; Nielsen, Morten Schak; Holstein-Rathlou, N.-H.

    In: Journal of Membrane Biology, Vol. 216, No. 1, 2007, p. 23-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    KCNQ channels are involved in the regulatory volume decrease response in primary neonatal rat cardiomyocytes. / Calloe, Kirstine; Nielsen, Morten Schak; Grunnet, Morten; Schmitt, Nicole; Jorgensen, Nanna Koschmieder.

    In: BBA General Subjects, Vol. 1773, No. 6, 2007, p. 764-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2006
  55. Published

    Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123). / Axelsen, Lene Nygaard; Stahlhut, Martin; Mohammed, Shabaz; Larsen, Bjarne Due; Nielsen, Morten S; Andersen, Søren; Jensen, Ole N; Hennan, James K; Kjølbye, Anne Louise; Holstein-Rathlou, N.-H.

    In: Journal of Molecular and Cellular Cardiology, Vol. 40, No. 6, 2006, p. 790-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Treatment with the gap junction modifier rotigaptide (ZP123) reduces infarct size in rats with chronic myocardial infarction. / Haugan, Ketil; Marcussen, Niels; Kjølbye, Anne Louise; Nielsen, Morten Schak; Hennan, James K; Petersen, Jørgen Søberg.

    In: Journal of Cardiovascular Pharmacology, Vol. 47, No. 2, 2006, p. 236-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2005
  58. Published

    The antiarrhythmic peptide analog ZP123 prevents atrial conduction slowing during metabolic stress. / Haugan, Ketil; Olsen, Kristine Boisen; Hartvig, Line; Petersen, Jørgen Søberg; Hennan, James K; Nielsen, Morten Schak; Holstein-Rathlou, N.-H.

    In: Cardiovascular Electrophysiology, Vol. 16, No. 5, 2005, p. 537-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 2003
  60. Published

    ZP123 increases gap junctional conductance and prevents reentrant ventricular tachycardia during myocardial ischemia in open chest dogs. / Xing, Dezhi; Kjølbye, Anne Louise; Nielsen, Morten S; Petersen, Jørgen S; Harlow, Kenneth W; Martins, James B; Holstein-Rathlou, N.-H.

    In: Cardiovascular Electrophysiology, Vol. 14, No. 5, 2003, p. 510-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2002
  62. Published

    KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current. / Angelo, Kamilla; Jespersen, Thomas; Grunnet, Morten; Nielsen, Morten Schak; Klaerke, Dan A; Olesen, Søren-Peter.

    In: Biophysical Journal, Vol. 83, No. 4, 2002, p. 1997-2006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2001
  64. Published

    Maxi K+ channels co-localised with CFTR in the apical membrane of an exocrine gland acinus: possible involvement in secretion. / Sørensen, Jakob Balslev; Nielsen, Morten Schak; Gudme, Charlotte Nini; Larsen, Erik Hviid; Nielsen, Robert.

    In: Pflügers Archiv: European Journal of Physiology, Vol. 442, 2001, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 1999
  66. Published

    Effect of carbachol and prostaglandin E2 on chloride secretion and signal transduction in the exocrine glands of frog skin (Rana esculenta). / Nielsen, Morten Schak; Nielsen, Robert.

    In: Pflügers Archiv: European Journal of Physiology, No. 438, 1999, p. 732-740.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. 1998
  68. Published

    The K+ channels of colonic crypts and their regulation. / Greger, R.; Hamm, K.; Warth, R.; Nielsen, Morten Schak; Weyand, B.; Ecke, D.; Riedemann, N.; Gerlach, U.; Busch, A. E.; Englert, H. C.; Hropot, M.; Lang, H. J.; Bleich, M.

    In: Korean Journal of Physiology and Pharmacology, Vol. 2, No. 4, 1998, p. 403-409.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The basolateral Ca2+-dependent K+ channel in rat colonic crypt cells. / Nielsen, M.S.; Warth, R.; Bleich, Markus; Weyand, B.; Greger, R.

    In: Pflügers Archiv: European Journal of Physiology, No. 435, 1998, p. 267-272.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. 1995
  71. Published

    Intracelllular calcium and ADH stimulated sodium transport in frog skin. / Bjerregaard, Henning; Nielsen, M.S.; Brodin, Birger.

    In: Pflügers Archiv: European Journal of Physiology, No. 430, 1995, p. R135 (Abstract).

    Research output: Contribution to journalConference abstract in journalResearch

  72. 1994
  73. Published

    K+ is actively secreted in the frog skin gland. / Nielsen, M.S.; Nielsen, Robert.

    In: Acta Physiologica (Print Edition), No. 151, 1994, p. 26A.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. 1993
  75. Published

    Regulation of cellular and paracellular ion fluxes in frog skin glands. / Nielsen, M.S.; Nielsen, Robert.

    Glasgow : XXXII Congress of the International Uni3, 1993. 21 p.

    Research output: Book/ReportBookResearch

ID: 6471