Matthias Mann

Matthias Mann

Research director, professor


  1. 2016
  2. Published

    Proteomics reveals the effects of sustained weight loss on the human plasma proteome. / Geyer, Philipp E; Wewer Albrechtsen, Nicolai J; Tyanova, Stefka; Grassl, Niklas; Iepsen, Eva Pers Winning; Lundgren, Julie; Madsbad, Sten; Holst, Jens J; Torekov, Signe S; Mann, Matthias.

    In: Molecular Systems Biology, Vol. 12, 901, 22.12.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. / Sivadasan, Rajeeve; Hornburg, Daniel; Drepper, Carsten; Frank, Nicolas; Jablonka, Sibylle; Hansel, Anna; Lojewski, Xenia; Sterneckert, Jared; Hermann, Andreas; Shaw, Pamela J; Ince, Paul G; Mann, Matthias; Meissner, Felix; Sendtner, Michael.

    In: Nature Neuroscience, Vol. 19, No. 12, 12.2016, p. 1610-1618.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry. / Bassani-Sternberg, Michal; Bräunlein, Eva; Klar, Richard; Engleitner, Thomas; Sinitcyn, Pavel; Audehm, Stefan; Straub, Melanie; Weber, Julia; Slotta-Huspenina, Julia; Specht, Katja; Martignoni, Marc E; Werner, Angelika; Hein, Rüdiger; H Busch, Dirk; Peschel, Christian; Rad, Roland; Cox, Jürgen; Mann, Matthias; Krackhardt, Angela M.

    In: Nature Communications, Vol. 7, 21.11.2016, p. 13404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. / Sacco, Francesca; Humphrey, Sean J; Cox, Jürgen; Mischnik, Marcel; Schulte, Anke; Klabunde, Thomas; Schäfer, Matthias; Mann, Matthias.

    In: Nature Communications, Vol. 7, 14.11.2016, p. 13250.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. / Hansen, Rebecca Kring; Mund, Andreas; Poulsen, Sara Lund; Sandoval, Maria; Klement, Karolin; Tsouroula, Katerina; Tollenaere, Maxim A X; Räschle, Markus; Soria, Rebeca; Offermanns, Stefan; Worzfeld, Thomas; Grosse, Robert; Brandt, Dominique T; Rozell, Björn; Mann, Matthias; Cole, Francesca; Soutoglou, Evi; Goodarzi, Aaron A; Daniel, Jeremy A; Mailand, Niels; Bekker-Jensen, Simon.

    In: Nature Cell Biology, Vol. 18, No. 12, 07.11.2016, p. 1357–1366.

    Research output: Contribution to journalLetterResearchpeer-review

  7. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1. / Haahr, Peter; Hoffmann, Saskia; Tollenaere, Maxim A X; Ho, Teresa; Toledo Lazaro, Luis Ignacio; Mann, Matthias; Bekker-Jensen, Simon; Räschle, Markus; Mailand, Niels.

    In: Nature Cell Biology, Vol. 18, No. 11, 11.2016, p. 1196–1207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Origins of mass spectrometry-based proteomics. / Mann, Matthias.

    In: Nature Reviews. Molecular Cell Biology, Vol. 17, No. 11, 11.2016, p. 678.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity. / Geiger, Roger; Rieckmann, Jan C; Wolf, Tobias; Basso, Camilla; Feng, Yuehan; Fuhrer, Tobias; Kogadeeva, Maria; Picotti, Paola; Meissner, Felix; Mann, Matthias; Zamboni, Nicola; Sallusto, Federica; Lanzavecchia, Antonio.

    In: Cell, Vol. 167, No. 3, 20.10.2016, p. 829-842.e13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes. / Wierer, Michael; Mann, Matthias.

    In: Human Molecular Genetics, Vol. 25, No. R2, 01.10.2016, p. R106-R114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Mass-spectrometric exploration of proteome structure and function. / Aebersold, Ruedi; Mann, Matthias.

    In: Nature, Vol. 537, No. 7620, 15.09.2016, p. 347-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors. / Kim, Yujin E; Hosp, Fabian; Frottin, Frédéric; Ge, Hui; Mann, Matthias; Hayer-Hartl, Manajit; Hartl, F Ulrich.

    In: Molecular Cell, Vol. 63, No. 6, 15.09.2016, p. 951-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. The Perseus computational platform for comprehensive analysis of (prote)omics data. / Tyanova, Stefka; Temu, Tikira; Sinitcyn, Pavel; Carlson, Arthur; Hein, Marco Y; Geiger, Tamar; Mann, Matthias; Cox, Jürgen.

    In: Nature Methods, Vol. 13, No. 9, 09.2016, p. 731-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1. / Ma-Lauer, Yue; Carbajo-Lozoya, Javier; Hein, Marco Y; Müller, Marcel A; Deng, Wen; Lei, Jian; Meyer, Benjamin; Kusov, Yuri; von Brunn, Brigitte; Bairad, Dev Raj; Hünten, Sabine; Drosten, Christian; Hermeking, Heiko; Leonhardt, Heinrich; Mann, Matthias; Hilgenfeld, Rolf; von Brunn, Albrecht.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 35, 30.08.2016, p. E5192-201.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans. / Holdt, Lesca M; Stahringer, Anika; Sass, Kristina; Pichler, Garwin; Kulak, Nils A; Wilfert, Wolfgang; Kohlmaier, Alexander; Herbst, Andreas; Northoff, Bernd H; Nicolaou, Alexandros; Gäbel, Gabor; Beutner, Frank; Scholz, Markus; Thiery, Joachim; Musunuru, Kiran; Krohn, Knut; Mann, Matthias; Teupser, Daniel.

    In: Nature Communications, Vol. 7, 19.08.2016, p. 12429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. HCD Fragmentation of Glycated Peptides. / Keilhauer, Eva C; Geyer, Philipp E; Mann, Matthias.

    In: Journal of Proteome Research, Vol. 15, No. 8, 05.08.2016, p. 2881-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease. / Schamberger, Andrea C; Schiller, Herbert B; Fernandez, Isis E; Sterclova, Martina; Heinzelmann, Katharina; Hennen, Elisabeth; Hatz, Rudolf; Behr, Jürgen; Vašáková, Martina; Mann, Matthias; Eickelberg, Oliver; Staab-Weijnitz, Claudia A.

    In: Scientific Reports, Vol. 6, 20.07.2016, p. 29952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. A Proteomics Approach to the Protein Normalization Problem : Selection of Unvarying Proteins for MS-Based Proteomics and Western Blotting. / Wiśniewski, Jacek R; Mann, Matthias.

    In: Journal of Proteome Research, Vol. 15, No. 7, 01.07.2016, p. 2321-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins. / Guerrera, Diego; Shah, Jimit; Vasileva, Ekaterina; Sluysmans, Sophie; Méan, Isabelle; Jond, Lionel; Poser, Ina; Mann, Matthias; Hyman, Anthony A; Citi, Sandra.

    In: The Journal of Biological Chemistry, Vol. 291, No. 21, 20.05.2016, p. 11016-29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells. / Graham, Bryony; Marcais, Antoine; Dharmalingam, Gopuraja; Carroll, Thomas; Kanellopoulou, Chryssa; Graumann, Johannes; Nesterova, Tatyana B; Bermange, Anna; Brazauskas, Pijus; Xella, Barbara; Kriaucionis, Skirmantas; Higgs, Douglas R; Brockdorff, Neil; Mann, Matthias; Fisher, Amanda G; Merkenschlager, Matthias.

    In: Stem Cell Reports, Vol. 6, No. 5, 10.05.2016, p. 635-642.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Homology-driven assembly of NOn-redundant protEin sequence sets (NOmESS) for mass spectrometry. / Temu, Tikira; Mann, Matthias; Räschle, Markus; Cox, Jürgen.

    In: Bioinformatics (Online), Vol. 32, No. 9, 01.05.2016, p. 1417-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC. / Frey, Felice; Sheahan, Thomas; Finkl, Katja; Stoehr, Gabriele; Mann, Matthias; Benda, Christian; Müller, Jürg.

    In: Genes & Development, Vol. 30, No. 9, 01.05.2016, p. 1116-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Inflammatory signaling in human tuberculosis granulomas is spatially organized. / Marakalala, Mohlopheni J; Raju, Ravikiran M; Sharma, Kirti; Zhang, Yanjia J; Eugenin, Eliseo A; Prideaux, Brendan; Daudelin, Isaac B; Chen, Pei-Yu; Booty, Matthew G; Kim, Jin Hee; Eum, Seok Yong; Via, Laura E; Behar, Samuel M; Barry, Clifton E; Mann, Matthias; Dartois, Véronique; Rubin, Eric J.

    In: Nature Medicine, Vol. 22, No. 5, 05.2016, p. 531-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    The Proteome of Primary Prostate Cancer. / Iglesias-Gato, Diego; Wikström, Pernilla; Tyanova, Stefka; Lavallee, Charlotte; Thysell, Elin; Carlsson, Jessica; Hägglöf, Christina; Cox, Jürgen; Andrén, Ove; Stattin, Pär; Egevad, Lars; Widmark, Anders; Bjartell, Anders; Collins, Colin C; Bergh, Anders; Geiger, Tamar; Mann, Matthias; Flores-Morales, Amilcar.

    In: European Urology, Vol. 69, No. 5, 05.2016, p. 942-952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Ultra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome. / Grassl, Niklas; Kulak, Nils Alexander; Pichler, Garwin; Geyer, Philipp Emanuel; Jung, Jette; Schubert, Sören; Sinitcyn, Pavel; Cox, Juergen; Mann, Matthias.

    In: Genome Medicine, Vol. 8, 44, 21.04.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4. / Di Stefano, Bruno; Collombet, Samuel; Jakobsen, Janus Schou; Wierer, Michael; Sardina, Jose Luis; Lackner, Andreas; Stadhouders, Ralph; Segura-Morales, Carolina; Francesconi, Mirko; Limone, Francesco; Mann, Matthias; Porse, Bo; Thieffry, Denis; Graf, Thomas.

    In: Nature Cell Biology, Vol. 18, No. 4, 04.2016, p. 371-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State. / Sacco, Francesca; Silvestri, Alessandra; Posca, Daniela; Pirrò, Stefano; Gherardini, Pier Federico; Castagnoli, Luisa; Mann, Matthias; Cesareni, Gianni.

    In: Cell Systems, Vol. 2, No. 3, 23.03.2016, p. 159-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Plasma Proteome Profiling to Assess Human Health and Disease. / Geyer, Philipp E; Kulak, Nils A; Pichler, Garwin; Holdt, Lesca M; Teupser, Daniel; Mann, Matthias.

    In: Cell Systems, Vol. 2, No. 3, 23.03.2016, p. 185-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins. / Neufeld-Cohen, Adi; Robles, Maria S; Aviram, Rona; Manella, Gal; Adamovich, Yaarit; Ladeuix, Benjamin; Nir, Dana; Rousso-Noori, Liat; Kuperman, Yael; Golik, Marina; Mann, Matthias; Asher, Gad.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 12, 22.03.2016, p. E1673-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Evidence of Extrapancreatic Glucagon Secretion in Man. / Lund, Asger; Bagger, Jonatan I; Wewer Albrechtsen, Nicolai J; Christensen, Mikkel; Grøndahl, Magnus; Hartmann, Bolette; Mathiesen, Elisabeth R; Hansen, Carsten P; Storkholm, Jan H; van Hall, Gerrit; Rehfeld, Jens F; Hornburg, Daniel; Meissner, Felix; Mann, Matthias; Larsen, Steen; Holst, Jens J; Lauritsen, Tina Vilsbøll; Knop, Filip K.

    In: Diabetes, Vol. 65, No. 3, 03.2016, p. 585-597.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. A genome-wide resource for the analysis of protein localisation in Drosophila. / Sarov, Mihail; Barz, Christiane; Jambor, Helena; Hein, Marco Y; Schmied, Christopher; Suchold, Dana; Stender, Bettina; Janosch, Stephan; K J, Vinay Vikas; Krishnan, R T; Krishnamoorthy, Aishwarya; Ferreira, Irene R S; Ejsmont, Radoslaw K; Finkl, Katja; Hasse, Susanne; Kämpfer, Philipp; Plewka, Nicole; Vinis, Elisabeth; Schloissnig, Siegfried; Knust, Elisabeth; Hartenstein, Volker; Mann, Matthias; Ramaswami, Mani; VijayRaghavan, K; Tomancak, Pavel; Schnorrer, Frank.

    In: eLife, Vol. 5, 20.02.2016, p. e12068.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. IKAP : A heuristic framework for inference of kinase activities from Phosphoproteomics data. / Mischnik, Marcel; Sacco, Francesca; Cox, Jürgen; Schneider, Hans-Christoph; Schäfer, Matthias; Hendlich, Manfred; Crowther, Daniel; Mann, Matthias; Klabunde, Thomas.

    In: Bioinformatics (Online), Vol. 32, No. 3, 01.02.2016, p. 424-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases. / Steger, Martin; Tonelli, Francesca; Ito, Genta; Davies, Paul; Trost, Matthias; Vetter, Melanie; Wachter, Stefanie; Lorentzen, Esben; Duddy, Graham; Wilson, Stephen; Baptista, Marco As; Fiske, Brian K; Fell, Matthew J; Morrow, John A; Reith, Alastair D; Alessi, Dario R; Mann, Matthias.

    In: eLife, Vol. 5, 29.01.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA. / Woerner, Andreas C; Frottin, Frédéric; Hornburg, Daniel; Feng, Li R; Meissner, Felix; Patra, Maria; Tatzelt, Jörg; Mann, Matthias; Winklhofer, Konstanze F; Hartl, F Ulrich; Hipp, Mark S.

    In: Science (New York, N.Y.), Vol. 351, No. 6269, 08.01.2016, p. 173-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Proteomic maps of breast cancer subtypes. / Tyanova, Stefka; Albrechtsen, Reidar; Kronqvist, Pauliina; Cox, Juergen; Mann, Matthias; Geiger, Tamar.

    In: Nature Communications, Vol. 7, 10259, 04.01.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. / Hoffmann, Saskia; Smedegaard, Stine; Nakamura, Kyosuke; Mortuza, Gulnahar B; Räschle, Markus; Ibañez de Opakua, Alain; Oka, Yasuyoshi; Feng, Yunpeng; Blanco, Francisco J; Mann, Matthias; Montoya, Guillermo; Groth, Anja; Bekker-Jensen, Simon; Mailand, Niels.

    In: The Journal of Cell Biology, Vol. 212, No. 1, 04.01.2016, p. 63-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5650809