Kaare Teilum

Kaare Teilum

Associate Professor


  1. 1999
  2. Published

    Disulfide bond formation and folding of plant peroxidases expressed as inclusion body protein in Escherichia coli thioredoxin reductase negative strains. / Teilum, K; Ostergaard, L; Welinder, K G.

    In: Protein Expression and Purification, Vol. 15, No. 1, 1999, p. 77-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2000
  4. Published

    Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification. / Ostergaard, L; Teilum, K; Mirza, O; Mattsson, O; Petersen, M; Welinder, K G; Mundy, J; Gajhede, M; Henriksen, A.

    In: Plant Molecular Biology, Vol. 44, No. 2, 2000, p. 231-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP. / Teilum, K; Kragelund, B B; Knudsen, J; Poulsen, F M.

    In: Journal of Molecular Biology, Vol. 301, No. 5, 2000, p. 1307-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2001
  7. Published

    Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions. / Henriksen, A; Mirza, O; Indiani, C; Teilum, K; Smulevich, G; Welinder, K G; Gajhede, M.

    In: Protein Science, Vol. 10, No. 1, 2001, p. 108-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2002
  9. Published

    Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing. / Teilum, Kaare; Maki, Kosuke; Kragelund, Birthe B; Poulsen, Flemming M; Roder, Heinrich.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 99, No. 15, 2002, p. 9807-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH. / Thomsen, Jens K; Kragelund, Birthe B; Teilum, Kaare; Knudsen, Jens; Poulsen, Flemming M.

    In: Journal of Molecular Biology, Vol. 318, No. 3, 2002, p. 805-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling. / Teilum, Kaare; Kragelund, Birthe B; Poulsen, Flemming M.

    In: Journal of Molecular Biology, Vol. 324, No. 2, 2002, p. 349-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2004
  13. Published

    Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein. / Lindorff-Larsen, Kresten; Kristjansdottir, Sigridur; Teilum, Kaare; Fieber, Wolfgang; Dobson, Christopher M; Poulsen, Flemming Martin; Vendruscolo, Michele.

    In: Journal of the American Chemical Society, Vol. 126, No. 10, 2004, p. 3291-3219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2005
  15. Published

    Application of Hydrogen Exchange Kinetics to Studies of Protein Folding. / Teilum, Kaare; Kragelund, Birthe Brandt; Poulsen, Flemming Martin.

    Protein Folding Handbook. ed. / Johannes Buchner; Thomas Kiefhaber. Weinheim : Wiley-VCH, 2005. p. 634-672.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles. / Teilum, Kaare; Thormann, Thorsten; Caterer, Nigel R.; Poulsen, Heidi I.; Jensen, Peter H.; Knudsen, Jens; Kragelund, Birthe Brandt; Poulsen, Flemming M.

    In: Proteins - Structure Function and Bioinformatics, Vol. 59, No. 1, 2005, p. 80-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Protein folding: Defining a standard set of experimental conditions and a preliminary kinetic data set of two-state proteins. / Maxwell, Karen L.; Wildes, D.; Zarrine-Afsar, A.; Rivos, Miguel A. De Los Rios; Brown, Andrew G.; Friel, Claire T.; Hedberg, Linda; Horng, Jia-Cherng; Bona, Diana; Miller, Erik J.; Vallée-Bélisle, Alexis; Main, Ewan R. G.; Bemporad, Francesco; Qiu, Linlin; Teilum, Kaare; Vu, Ngoc-Diep; Edwards, Aled M.; Ruczinski, Ingo; Poulsen, Flemming M.; Kragelund, Birthe Brandt; Michnick, Stephen W.; Chiti, Fabrizio; Bai, Yawen; Hagen, Stephen J.; Serrano, Luis; Oliveberg, Mikael; Raleigh, Daniel P.; Stafshede, Pernilla Wittung; Radford, Sheena E.; Jackson, Sophie e.; Sosnick, Tobin R.; Margusee, Susan; Davidson, Alan R.; Plaxco, Kevin W.

    In: Protein Science, Vol. 14, No. 3, 2005, p. 602-616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Solution structure of human prolactin. / Teilum, Kaare; Hoch, Jeffrey C; Goffin, Vincent; Kinet, Sandrina; Martial, Joseph A; Kragelund, Birthe B.

    In: Journal of Molecular Biology, Vol. 351, No. 4, 2005, p. 810-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2006
  20. Biosynthetic 13C labeling of aromatic side chains in proteins for NMR relaxation measurements. / Teilum, Kaare; Brath, Ulrika; Lundström, Patrik; Akke, Mikael.

    In: Journal of the American Chemical Society, Vol. 128, No. 8, 2006, p. 2506-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Solution structures of human and porcine beta-microseminoprotein. / Ghasriani, Houman; Teilum, Kaare; Johnsson, Ylva; Fernlund, Per; Drakenberg, Torbjörn.

    In: Journal of Molecular Biology, Vol. 362, No. 3, 2006, p. 502-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein. / Teilum, Kaare; Poulsen, Flemming M; Akke, Mikael.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 103, No. 18, 2006, p. 6877-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein. / Teilum, Kaare; Poulsen, F. M.; Akke, M.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 103, No. 18, 2006, p. 6867-6882.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2007
  25. Fractional 13C enrichment of isolated carbons using [1-13C]- or [2- 13C]-glucose facilitates the accurate measurement of dynamics at backbone Calpha and side-chain methyl positions in proteins. / Lundström, Patrik; Teilum, Kaare; Carstensen, Tommy; Bezsonova, Irina; Wiesner, Silke; Hansen, D Flemming; Religa, Tomasz L; Akke, Mikael; Kay, Lewis E.

    In: Journal of Biomolecular NMR, Vol. 38, No. 3, 2007, p. 199-212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2009
  27. Published

    Functional aspects of protein flexibility. / Teilum, Kaare; Olsen, Johan G; Kragelund, Birthe B.

    In: Cellular and Molecular Life Sciences, Vol. 66, No. 14, 2009, p. 2231-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
    Solution structure of the second Fibronectin type-III module of NCAM2. Rasmussen, Kim Krighaar (Other); Teilum, Kaare (Other); Kulahin, Nikolaj (Other); Clausen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Poulsen, Flemming (Other). 2009.

    Research output: Non-textual formDatasetResearch

  29. Published

    Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization. / Teilum, Kaare; Smith, Melanie H; Schulz, Eike; Christensen, Lea C; Solomentsev, Gleb; Oliveberg, Mikael; Akke, Mikael.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 106, No. 43, 2009, p. 18273-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2010
  31. Published

    Conformational selection in the molten globule state of the nuclear coactivator binding domain of CBP. / Kjærgaard, Magnus; Teilum, Kaare; Poulsen, Flemming M.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 107, No. 28, 2010, p. 12535-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2011
  33. Published

    Millisecond dynamics in glutaredoxin during catalytic turnover is dependent on substrate binding and absent in the resting states. / Jensen, Kristine Steen; Winther, Jakob R; Teilum, Kaare.

    In: Journal of the American Chemical Society, Vol. 133, No. 9, 2011, p. 3034-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Protein stability, flexibility and function. / Teilum, Kaare; Olsen, Johan G; Kragelund, Birthe B.

    In: B B A - Proteins and Proteomics, Vol. 1814, No. 8, 2011, p. 969-76.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides. / Pedersen, Jeppe Trudslev; Teilum, Kaare; Heegaard, Niels H. H. ; Østergaard, Jesper; Adolph, Hans-Werner; Hemmingsen, Lars Bo Stegeager.

    In: Angewandte Chemie International Edition, Vol. 50, No. 11, 2011, p. 2532-2535.

    Research output: Contribution to journalLetterResearchpeer-review

  36. Published

    Remeasuring HEWL pKa values by NMR spectroscopy  : methods, analysis, accuracy, and implications for theoretical pKa calculations. / Webb, Helen; Tynan-Connolly, Barbara Mary; Lee, Gregory M; Farrell, Damien; O'Meara, Fergal; Søndergaard, Chresten R; Teilum, Kaare; Hewage, Chandralal; McIntosh, Lawrence P; Nielsen, Jens Erik.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 79, No. 3, 2011, p. 685-702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2012
  38. Published

    Is a malleable protein necessarily highly dynamic? The hydrophobic core of the nuclear coactivator binding domain is well ordered. / Kjærgaard, Magnus; Poulsen, Flemming Martin; Teilum, Kaare.

    In: Biophysical Journal, Vol. 102, No. 7, 2012, p. 1627-1635.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation : insight from structures of the prolactin receptor. / Dagil, Robert; Knudsen, Maiken J.; Olsen, Johan Gotthardt; O'Shea, Charlotte; Franzmann, Magnus; Goffin, Vincent; Teilum, Kaare; Breinholt, Jens; Kragelund, Birthe Brandt.

    In: Structure, Vol. 20, No. 2, 2012, p. 270-282.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The human selenoprotein VCP-interacting membrane protein (VIMP) is non-globular and harbors a reductase function in an intrinsically disordered region. / Christensen, Lea Cecilie; Jensen, Njal Winther; Lages Lino Vala, Andrea; Kamarauskaite, Jurate; Johansson, Linda Christina; Winther, Jakob R.; Hofmann, Kay; Teilum, Kaare; Ellgaard, Lars.

    In: Journal of Biological Chemistry, Vol. 287, No. 31, 2012, p. 26388-26399.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2013
  42. Published

    A Folded Excited State of Ligand-Free Nuclear Coactivator Binding Domain (NCBD) Underlies Plasticity in Ligand Recognition. / Kjaergaard, Magnus; Andersen, Lisbeth; Nielsen, Lau Dalby; Teilum, Kaare.

    In: Biochemistry, Vol. 52, No. 10, 2013, p. 1686-1693.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Protein dielectric constants determined from NMR chemical shift perturbations. / Kukic, Predrag; Farrell, Damien; McIntosh, Lawrence P.; García-Moreno E., Bertrand; Jensen, Kristine Steen; Toleikis, Zigmantas; Teilum, Kaare; Nielsen, Jens Erik.

    In: Journal of the American Chemical Society, Vol. 135, No. 45, 2013, p. 16968–16976.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2014
  45. Published

    Binding of Cu2+ to the islet amyloid polypeptide (IAPP). / Andersen-Usaj, Jacob; Bonde, Amalie C.; Pihl, Jessica; Thomsen, Marie-Louise F.; Shavit, Miki; Pedersen, Jeppe Trudslev; Teilum, Kaare; Thulstrup, Peter Waaben; Hemmingsen, Lars Bo Stegeager.

    In: Journal of Biological Inorganic Chemistry, Vol. 19, No. suppl. 2, P 101, 2014, p. S812.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Helical propensity in an intrinsically disordered protein accelerates ligand binding. / Iesmantavicius, Vytautas; Dogan, Jakob; Jemth, Per; Teilum, Kaare; Kjærgaard, Magnus.

    In: Angewandte Chemie (International ed. in English), Vol. 53, No. 6, 2014, p. 1548-1551.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Islet amyloid polypeptide (IAPP)-Structural effects of Zn2+. / Shavit, Miki; Bonde, Amalie Carnbring; Pihl, Jessica; Thomsen, Marie-Louise F; Pedersen, Jeppe Trudslev; Andersen-Usaj, Jacob; Teilum, Kaare; Hemmingsen, Lars Bo Stegeager; Thulstrup, Peter Waaben.

    In: Journal of Biological Inorganic Chemistry, Vol. 19, No. Suppl. 2, P 102, 2014, p. S813.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  48. Published

    Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection. / Weininger, Ulrich; Brath, Ulrika; Modig, Kristofer; Teilum, Kaare; Akke, Mikael.

    In: Journal of Biomolecular NMR, Vol. 59, No. 1, 2014, p. 23-29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/Discs-Large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands. / Erlendsson, Simon; Rathje, Mette; Heiðarsson, Pétur Orri; Poulsen, Flemming Martin; Madsen, Kenneth Lindegaard; Teilum, Kaare; Gether, Ulrik.

    In: Journal of Biological Chemistry, Vol. 289, No. 36, 2014, p. 25327-25340.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The pKa value and accessibility of cysteine residues are key determinants for protein substrate discrimination by glutaredoxin. / Jensen, Kristine Steen; Pedersen, Jeppe Trudslev; Winther, Jakob R.; Teilum, Kaare.

    In: Biochemistry, Vol. 53, No. 15, 2014, p. 2533-2540.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    pH dependence of amyloid-β-Cu(II) binding and oligomerization kinetics. / Pedersen, Jeppe Trudslev; Borg, Christian B.; Teilum, Kaare; Hemmingsen, Lars Bo Stegeager.

    In: Journal of Biological Inorganic Chemistry, Vol. 19, No. Suppl 2, 2014, p. S755.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  52. Published

    relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data. / Morin, Sebastien; Linnet, Troels Emtekær; Lescanne, Mathilde; Schanda, Paul; Thompson, Gary S.; Tollinger, Martin; Teilum, Kaare; Gagne, Stephane; Marion, Dominique; Griesinger, Christian; Blackledge, Martin; d’Auvergne, Edward J.

    In: Bioinformatics, Vol. 30, No. 15, 2014, p. 2219-2220.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2015
  54. Published

    Aggregation prone amyloid-β⋅CuII Species formed on the millisecond timescale at mildly acidic conditions. / Pedersen, Jeppe Trudslev; Borg, Christian Bernsen; Michaels, Thomas C. T.; Knowles, Tuomas P. J.; Faller, Peter; Teilum, Kaare; Hemmingsen, Lars Bo Stegeager.

    In: ChemBioChem, Vol. 16, No. 9, 2015, p. 1293-1297.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Globular and disordered-the non-identical twins in protein-protein interactions. / Teilum, Kaare; Olsen, Johan Gotthardt; Kragelund, Birthe Brandt.

    In: Frontiers in Bioscience, Vol. 2, 40, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering. / Karlsen, Morten L.; Thorsen, Thor S.; Johner, Niklaus; Ammendrup-Johnsen, Ina; Erlendsson, Simon; Tian, Xinsheng; Simonsen, Jens B.; Hoiberg-Nielsen, Rasmus; Christensen, Nikolaj M.; Khelashvili, George; Streicher, Werner; Teilum, Kaare; Vestergaard, Bente; Weinstein, Harel; Gether, Ulrik; Arleth, Lise; Madsen, Kenneth L.

    In: Structure, Vol. 23, No. 7, 07.07.2015, p. 1258-1270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2016
  58. Published

    A soluble, folded protein without charged amino acid residues. / Højgaard, Casper; Kofoed, Christian; Espersen, Roall; Johansson, Kristoffer Enøe; Villa, Mara; Willemoës, Martin; Lindorff-Larsen, Kresten; Teilum, Kaare; Winther, Jakob R.

    In: Biochemistry, Vol. 55, No. 28, 2016, p. 3949–3956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Amyloid-β and α-synuclein decrease the level of metal-catalyzed reactive oxygen species by radical scavenging and redox silencing. / Pedersen, Jeppe Trudslev; Chen, Serene W.; Borg, Christian Bernsen; Ness, Samuel; Bahl, Justyna M.; Heegard, Niels H. H.; Dobson, Christopher M.; Hemmingsen, Lars Bo Stegeager; Cremades, Nunilo; Teilum, Kaare.

    In: Journal of the American Chemical Society, Vol. 138, No. 12, 2016, p. 3966-3969.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Non-uniform sampling of NMR relaxation data. / Schwarz-Linnet, Troels; Teilum, Kaare.

    In: Journal of Biomolecular N M R, Vol. 64, No. 2, 2016, p. 165-173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2017
  62. Published

    Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR. / Erlendsson, Simon; Gotfryd, Kamil; Larsen, Flemming Hofmann; Mortensen, Jonas Sigurd; Geiger, Michel-Andreas; van Rossum, Barth-Jan; Oschkinat, Hartmut; Gether, Ulrik; Teilum, Kaare; Løland, Claus Juul.

    In: eLife, Vol. 6, e19314, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+-Aβ Complex. / Somavarapu, Arun Kumar; Shen, Fei; Teilum, Kaare; Zhang, Jingdong; Mossin, Susanne; Thulstrup, Peter W.; Bjerrum, Morten J.; Tiwari, Manish K.; Szunyogh, Daniel; Søtofte, Peter M.; Kepp, Kasper P.; Hemmingsen, Lars.

    In: Chemistry - A European Journal, Vol. 23, No. 55, 2017, p. 13591-13595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    (S)Pinning down protein interactions by NMR. / Teilum, Kaare; Kunze, Micha Ben Achim; Erlendsson, Simon; Kragelund, Birthe Brandt.

    In: Protein Science, Vol. 26, No. 3, 03.2017, p. 436-451.

    Research output: Contribution to journalReviewResearchpeer-review

  65. Published

    Structure of the competence pilus major pilin ComGC in Streptococcus pneumoniae. / Muschiol, Sandra; Erlendsson, Simon; Aschtgen, Marie-Stephanie; Oliveira, Vitor; Schmieder, Peter; de Lichtenberg, Casper; Teilum, Kaare; Boesen, Thomas; Akbey, Umit; Henriques-Normark, Birgitta.

    In: Journal of Biological Chemistry, Vol. 292, No. 34, 25.08.2017, p. 14134-14146.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness. / Olsen, Johan Gotthardt; Teilum, Kaare; Kragelund, Birthe Brandt.

    In: Cellular and Molecular Life Sciences, Vol. 74, No. 17, 09.2017, p. 3175-3183.

    Research output: Contribution to journalReviewResearchpeer-review

  67. Published

    The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications. / Stiefler-Jensen, Daniel; Schwarz-Linnet, Troels; de Lichtenberg, Casper; Nguyen, Tam T. T. N.; Rand, Kasper Dyrberg; Huang, Li; She, Qunxin; Teilum, Kaare.

    In: Protein Science, Vol. 26, No. 9, 09.2017, p. 1819-1827.

    Research output: Contribution to journalJournal articleResearchpeer-review

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