Jens Juul Holst
Professor
Integrative Metabolism and Environmental Influences
Blegdamsvej 3B
2200 København N
Denmark
Blegdamsvej 3B
København N København N
Endocrinology and Metabolism
Blegdamsvej 3B, 2200 København N
Juul Holst Group
Blegdamsvej 3B, 2200 København N
- 2009
- Published
Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion. / Müssig, Karsten; Staiger, Harald; Machicao, Fausto; Kirchhoff, Kerstin; Guthoff, Martina; Schäfer, Silke A; Kantartzis, Konstantinos; Silbernagel, Günther; Stefan, Norbert; Holst, Jens J; Gallwitz, Baptist; Häring, Hans-Ulrich; Fritsche, Andreas.
In: Diabetes, Vol. 58, No. 7, 2009, p. 1715-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian rhythms of GIP and GLP1 in glucose-tolerant and in type 2 diabetic patients after biliopancreatic diversion. / Mingrone, G; Nolfe, G; Gissey, G Castagneto; Iaconelli, A; Leccesi, L; Guidone, C; Nanni, G; Holst, Jens Juul.
In: Diabetologia, Vol. 52, No. 5, 2009, p. 873-81.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity. / Høi-Hansen, Thomas; Pedersen-Bjergaard, Ulrik; Andersen, Rikke Due; Kristensen, Peter Lommer; Thomsen, Carsten; Kjaer, Troels; Høgenhaven, Hans; Smed, Annelise; Holst, Jens Juul; Dela, Flemming; Boomsma, Frans; Thorsteinsson, Birger; Høi-Hansen, Thomas; Pedersen-Bjergaard, Ulrik; Andersen, Rikke Due; Kristensen, Peter Lommer; Thomsen, Carsten; Kjaer, Troels; Høgenhaven, Hans; Smed, Annelise; Holst, Jens Juul; Dela, Flemming; Boomsma, Frans; Thorsteinsson, Birger.
In: Journal of the Renin-Angiotensin-Aldosterone System, Vol. 10, No. 4, 2009, p. 216-29.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. / Shang, Quan; Saumoy, Monica; Holst, Jens Juul; Salen, Gerald; Xu, Guorong.
In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 298, No. 3, 2009, p. G419-24.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic GLP-2 is not sufficient to promote jejunal adaptation in a PN-dependent rat model of human short bowel syndrome. / Koopmann, Matthew C; Liu, Xiaowen; Boehler, Christopher J; Murali, Sangita G; Holst, Jens J; Ney, Denise M.
In: Journal of Parenteral and Enteral Nutrition, Vol. 33, No. 6, 2009, p. 629-38; discussion 638-9.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative effect of orally administered sodium butyrate before or after weaning on growth and several indices of gastrointestinal biology of piglets. / Le Gall, Maud; Gallois, Mélanie; Sève, Bernard; Louveau, Isabelle; Holst, Jens J; Oswald, Isabelle P; Lallès, Jean-Paul; Guilloteau, Paul.
In: British Journal of Nutrition, Vol. 102, No. 9, 2009, p. 1285-96.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DPP-4 inhibition – advances in our understanding of diabetes management. / Deacon, Carolyn F.; Holst, Jens Juul.
In: European Endocrinology, Vol. 4, 2009, p. 47-49.Research output: Contribution to journal › Review › Research
- Published
Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man. / Witte, A-B; Grybäck, P; Holst, Jens Juul; Hilsted, L; Hellström, P M; Jacobsson, H; Schmidt, P T.
In: Regulatory Peptides, Vol. 158, No. 1-3, 2009, p. 57-62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein. / Mortensen, Lene S; Hartvigsen, Merete L; Brader, Lea J; Astrup, Arne; Schrezenmeir, Jürgen; Holst, Jens J; Thomsen, Claus; Hermansen, Kjeld.
In: American Journal of Clinical Nutrition, Vol. 90, No. 1, 2009, p. 41-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery. / Guldstrand, M; Ahrén, B; Näslund, E; Holst, Jens Juul; Adamson, U.
In: Diabetes, Obesity and Metabolism, Vol. 11, No. 11, 2009, p. 1027-33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of sodium butyrate supplementation in milk replacer and starter diet on rumen development in calves. / Gorka, P; Kowalski, Z M; Pietrzak, P; Kotunia, A; Kiljanczyk, R; Flaga, J; Holst, Jens Juul; Guilloteau, P; Zabielski, R.
In: Journal of Physiology and Pharmacology, Vol. 60 Suppl 3, 2009, p. 47-53.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of viscosity on appetite and gastro-intestinal hormones. / Zijlstra, Nicolien; Mars, Monica; de Wijk, René A; Westerterp-Plantenga, Margriet S; Holst, Jens Juul; de Graaf, Cees.
In: Physiology & Behavior, Vol. 97, No. 1, 2009, p. 68-75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects. / Hlebowicz, Joanna; Hlebowicz, Anna; Lindstedt, Sandra; Björgell, Ola; Höglund, Peter; Holst, Jens J; Darwiche, Gassan; Almér, Lars-Olof.
In: American Journal of Clinical Nutrition, Vol. 89, No. 3, 2009, p. 815-21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of meal size and composition on incretin, alpha-cell, and beta-cell responses. / Rijkelijkhuizen, Josina M; McQuarrie, Kelly; Girman, Cynthia J; Stein, Peter P; Mari, Andrea; Holst, Jens J; Nijpels, Giel; Dekker, Jacqueline M.
In: Metabolism - Clinical and Experimental, 2009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD. / Henriksen, Dennis B; Alexandersen, Peter; Hartmann, Bolette; Adrian, Charlotte L; Byrjalsen, Inger; Bone, Henry G; Holst, Jens J; Christiansen, Claus.
In: Bone, Vol. 45, No. 5, 2009, p. 833-42.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction. / Holst, Birgitte; Egerod, Kristoffer L; Jin, Chunyu; Petersen, Pia Steen; Østergaard, Mette Viberg; Hald, Jacob; Sprinkel, A M Ejernaes; Størling, Joachim; Mandrup-Poulsen, Thomas; Holst, Jens J; Thams, Peter; Orskov, Cathrine; Wierup, Nils; Sundler, Frank; Madsen, Ole D; Schwartz, Thue W.
In: Endocrinology, Vol. 150, No. 6, 2009, p. 2577-85.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes. / Holst, Jens Juul; Seino, Yutaka.
In: Diabetes Research and Clinical Practice, Vol. 85, No. 1, 2009, p. 1-3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans. / Vollmer, Kirsten; Gardiwal, Husai; Menge, Bjoern A; Goetze, Oliver; Deacon, Carolyn F; Schmidt, Wolfgang E; Holst, Jens Juul; Meier, Juris J.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 4, 2009, p. 1379-85.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoassays for the incretin hormones GIP and GLP-1. / Deacon, Carolyn F; Holst, Jens J.
In: Best Practice & Research: Clinical Endocrinology & Metabolism, Vol. 23, No. 4, 2009, p. 425-32.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired glucose-induced glucagon suppression after partial pancreatectomy. / Schrader, Henning; Menge, Bjoern A; Breuer, Thomas G K; Ritter, Peter R; Uhl, Waldemar; Schmidt, Wolfgang E; Holst, Jens J; Meier, Juris J.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 8, 2009, p. 2857-63.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved tolerance to sequential glucose loading (Staub-Traugott effect): size and mechanisms. / Bonuccelli, Sandra; Muscelli, Elza; Gastaldelli, Amalia; Barsotti, Elisabetta; Astiarraga, Brenno D; Holst, Jens J; Mari, Andrea; Ferrannini, Ele.
In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 297, No. 2, 2009, p. E532-7.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin. / Svendsen, Pernille Fog; Nilas, Lisbeth; Madsbad, Sten; Holst, Jens Juul; Svendsen, Pernille Fog; Nilas, Lisbeth; Madsbad, Sten; Holst, Jens Juul.
In: Metabolism - Clinical and Experimental, Vol. 58, No. 5, 2009, p. 586-93.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones and diabetes mellitus. / Vilsbøll, Tina; Knop, Filip Krag; Deacon, Carolyn F.; Holst, Jens Juul.
Therapeutic Strategies in Diabetes. ed. / Coen D.A. Stehouwer; Nicolaas Schaper. Oxford : Clinical Publishing, 2009. p. 99-114.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Incretin-based therapy of type 2 diabetes mellitus. / Knop, Filip K; Vilsbøll, Tina; Holst, Jens J.
In: Current Protein and Peptide Science, Vol. 10, No. 1, 2009, p. 46-55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats. / Simonsen, L; Pilgaard, S; Carr, R D; Kanstrup, A B; Holst, Jens Juul; Deacon, C F.
In: Hormone and Metabolic Research, Vol. 41, No. 11, 2009, p. 851-3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsbøll, Tina; Vølund, A; Simonsen, U; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2009, p. 603-608.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kirurgisk behandling af type 2-diabetes. / Olesen, Stine Chabert; Hansen, Dorte Lindqvist; Almdal, Thomas; Bendtsen, Flemming; Nordgaard, Inge; Hvolris, Lisbeth Edvardsen; Holst, Jens J; Naver, Lars; Madsbad, Sten.
In: Ugeskrift for læger, Vol. 171, No. 8, 2009, p. 615-7.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus. / Christensen, Mikkel; Knop, Filip K; Holst, Jens J; Vilsboll, Tina.
In: IDrugs. The Investigational Drugs Journal, Vol. 12, No. 8, 2009, p. 503-13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats. / Simonsen, L; Pilgaard, S; Orskov, C; Hartmann, B; Holst, Jens Juul; Deacon, C F.
In: Diabetes, Obesity and Metabolism, Vol. 11, No. 9, 2009, p. 884-90.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of Gastric Emptying Disturbances in Chronic and Acute Inflammation of the Distal Gastrointestinal Tract. / Keller, Jutta; Beglinger, Christoph; Holst, Jens Juul; Andresen, Viola; Layer, Peter.
In: American Journal of Physiology: Gastrointestinal and Liver Physiology, 2009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutritional effects of the serial transverse enteroplasty procedure in experimental short bowel syndrome. / Kaji, Tatsuru; Tanaka, Hiroaki; Wallace, Laurie E; Kravarusic, Dragan; Holst, Jens Juul; Sigalet, David L.
In: European Journal of Pediatric Surgery. Supplement, Vol. 44, No. 8, 2009, p. 1552-9.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass. / Gelling, Richard W; Vuguin, Patricia M; Du, Xiu Quan; Cui, Lingguang; Rømer, John; Pederson, Raymond A; Leiser, Margarita; Sørensen, Heidi; Holst, Jens J; Fledelius, Christian; Johansen, Peter B; Fleischer, Norman; McIntosh, Christopher H S; Nishimura, Erica; Charron, Maureen J.
In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 297, No. 3, 2009, p. E695-707.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes? / Faerch, K; Borch-Johnsen, K; Holst, Jens Juul; Vaag, A.
In: Diabetologia, Vol. 52, No. 9, 2009, p. 1714-23.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus. / Müssig, Karsten; Staiger, Harald; Machicao, Fausto; Machann, Jürgen; Schick, Fritz; Schäfer, Silke A; Claussen, Claus D; Holst, Jens J; Gallwitz, Baptist; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich.
In: Metabolism - Clinical and Experimental, Vol. 58, No. 12, 2009, p. 1809-11.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus. / Hare, Kristine J; Knop, Filip K; Asmar, Meena; Madsbad, Sten; Deacon, Carolyn F; Holst, Jens J; Vilsbøll, Tina.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 12, 2009, p. 4679-87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat. / Bucinskaite, V; Tolessa, T; Pedersen, J; Rydqvist, B; Zerihun, L; Holst, Jens Juul; Hellström, P M.
In: Neurogastroenterology and Motility, Vol. 21, No. 9, 2009, p. 978-e78.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease. / Nathanson, D; Zethelius, B; Berne, C; Holst, Jens Juul; Sjöholm, A; Nyström, T.
In: Diabetologia, Vol. 53, No. 2, 2009, p. 277-80.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remission af type 2-diabetes efter gastric bypass-kirurgi : et medicinsk mysterium? / Jacobsen, Siv; Hansen, Dorte Lindqvist; Worm, Dorte; Madsbad, Sten; Hvolris, Lisbeth Edvardsen; Naver, Lars Peter Skat; Holst, Jens Juul.
In: Behandlerbladet, 2009, p. 20-29.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens J.
In: Advances in Therapy, Vol. 26, No. 5, 2009, p. 488-99.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. / Patti, Mary-Elizabeth; Houten, Sander M; Bianco, Antonio C; Bernier, Raquel; Larsen, P Reed; Holst, Jens J; Badman, Michael K; Maratos-Flier, Eleftheria; Mun, Edward C; Pihlajamaki, Jussi; Auwerx, Johan; Goldfine, Allison B.
In: Obesity, Vol. 17, No. 9, 2009, p. 1671-7.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short bowel patients treated for two years with glucagon-like Peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function. / Jeppesen, P B; Lund, P; Gottschalck, I B; Nielsen, H B; Holst, Jens Juul; Mortensen, J; Poulsen, S S; Quistorff, B; Mortensen, P B.
In: Gastroenterology Research and Practice, Vol. 2009, 2009, p. 616054.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short bowel patients treated for two years with glucagon-like peptide 2 (GLP-2): compliance, safety, and effects on quality of life. / Jeppesen, P B; Lund, P; Gottschalck, I B; Nielsen, H B; Holst, Jens Juul; Mortensen, J; Poulsen, S S; Quistorff, Bjørn; Mortensen, P B.
In: Gastroenterology Research and Practice, Vol. 2009, 2009, p. 425759.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets. / Vidarsdottir, Solrun; Roelfsema, Ferdinand; Streefland, Trea; Holst, Jens J; Rehfeld, Jens F; Pijl, Hanno.
In: European Journal of Endocrinology, Vol. 162, No. 1, 2009, p. 75-83.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs. / Bosch, Guido; Verbrugghe, Adronie; Hesta, Myriam; Holst, Jens J; van der Poel, Antonius F B; Janssens, Geert P J; Hendriks, Wouter H.
In: British Journal of Nutrition, Vol. 102, No. 2, 2009, p. 318-25.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The spectrum of antidiabetic actions of GLP-1 in patients with diabetes. / Vilsbøll, Tina; Holst, Jens J; Knop, Filip K.
In: Best Practice & Research: Clinical Endocrinology & Metabolism, Vol. 23, No. 4, 2009, p. 453-62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists. / Hansen, K B; Knop, F K; Holst, Jens Juul; Vilsbøll, T.
In: International Journal of Clinical Practice, Vol. 63, No. 8, 2009, p. 1154-60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial. / Aaboe, K.; Knop, F.K.; Vilsbøll, Tina; Deacon, Carolyn F.; Holst, Jens Juul; Madsbad, S.; Krarup, T.
In: Diabetologia, 2009, p. 748.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Whey protein potentiates the intestinotrophic action of glucagon-like peptide-2 in parenterally fed rats. / Liu, Xiaowen; Murali, Sangita G; Holst, Jens J; Ney, Denise M.
In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 297, No. 5, 2009, p. R1554-62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone secretion in women with polycystic ovary syndrome : roles of obesity, insulin sensitivity, and treatment with metformin. / Svendsen, Pernille Fog; Nilas, Lisbeth; Madsbad, Sten; Holst, Jens Juul.
In: Metabolism, Vol. 58, No. 5, 05.2009, p. 586-93.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects : A H2 15O positron emission tomographic study. / Bie-Olsen, Lise G; Kjaer, Troels W; Pedersen-Bjergaard, Ulrik; Lonsdale, Markus N; Holst, Jens Juul; Law, Ian; Thorsteinsson, Birger.
In: Journal of Neuroscience Research, Vol. 87, No. 8, 06.2009, p. 1922-1928.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
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